CN104641231B - 营养制品和医药产品的基于细胞的质量控制生物测定 - Google Patents

营养制品和医药产品的基于细胞的质量控制生物测定 Download PDF

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Publication number
CN104641231B
CN104641231B CN201380031597.XA CN201380031597A CN104641231B CN 104641231 B CN104641231 B CN 104641231B CN 201380031597 A CN201380031597 A CN 201380031597A CN 104641231 B CN104641231 B CN 104641231B
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sample
accession number
translation initiation
number pta
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CN104641231A (zh
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乔斯·A·霍尔珀林
迈克尔·乌勒
胡赛因·阿克塔斯
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Harvard University
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Harvard University
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5011Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing antineoplastic activity
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/502Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
    • G01N33/5023Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on expression patterns
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0693Tumour cells; Cancer cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/02Food
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Toxicology (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201380031597.XA 2012-07-20 2013-07-22 营养制品和医药产品的基于细胞的质量控制生物测定 Expired - Fee Related CN104641231B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261674180P 2012-07-20 2012-07-20
US61/674,180 2012-07-20
PCT/US2013/051433 WO2014015328A1 (en) 2012-07-20 2013-07-22 Cell based quality control bioassays for nutriceutical and medicinal products

Publications (2)

Publication Number Publication Date
CN104641231A CN104641231A (zh) 2015-05-20
CN104641231B true CN104641231B (zh) 2016-09-07

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CN201380031597.XA Expired - Fee Related CN104641231B (zh) 2012-07-20 2013-07-22 营养制品和医药产品的基于细胞的质量控制生物测定

Country Status (22)

Country Link
US (1) US9952200B2 (https=)
EP (1) EP2820418B1 (https=)
JP (1) JP6200501B2 (https=)
KR (1) KR102136763B1 (https=)
CN (1) CN104641231B (https=)
AU (1) AU2013292266B2 (https=)
CA (1) CA2866175C (https=)
CL (1) CL2014002530A1 (https=)
CO (1) CO7151536A2 (https=)
DK (1) DK2820418T3 (https=)
ES (1) ES2656941T3 (https=)
HU (1) HUE036166T2 (https=)
IN (1) IN2014DN07866A (https=)
MA (1) MA35924B1 (https=)
MX (1) MX356147B (https=)
NO (1) NO2912013T3 (https=)
PE (1) PE20142297A1 (https=)
PL (1) PL2820418T3 (https=)
PT (1) PT2820418T (https=)
RU (1) RU2662358C2 (https=)
WO (1) WO2014015328A1 (https=)
ZA (1) ZA201406653B (https=)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107217087B (zh) * 2016-03-22 2019-12-10 中国石油化工股份有限公司 迅速测量油田污水和成品油中细菌含量的方法
CN115785247B (zh) * 2022-12-22 2025-06-24 中国农业大学 一种猪流行性腹泻病毒抗性相关蛋白质eif2a及其相关生物材料和应用

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US4683195A (en) 1986-01-30 1987-07-28 Cetus Corporation Process for amplifying, detecting, and/or-cloning nucleic acid sequences
US4683202A (en) 1985-03-28 1987-07-28 Cetus Corporation Process for amplifying nucleic acid sequences
US4757141A (en) 1985-08-26 1988-07-12 Applied Biosystems, Incorporated Amino-derivatized phosphite and phosphate linking agents, phosphoramidite precursors, and useful conjugates thereof
US5091519A (en) 1986-05-01 1992-02-25 Amoco Corporation Nucleotide compositions with linking groups
US5151507A (en) 1986-07-02 1992-09-29 E. I. Du Pont De Nemours And Company Alkynylamino-nucleotides
US4843155A (en) 1987-11-19 1989-06-27 Piotr Chomczynski Product and process for isolating RNA
US5066580A (en) 1988-08-31 1991-11-19 Becton Dickinson And Company Xanthene dyes that emit to the red of fluorescein
US5366860A (en) 1989-09-29 1994-11-22 Applied Biosystems, Inc. Spectrally resolvable rhodamine dyes for nucleic acid sequence determination
US5188934A (en) 1989-11-14 1993-02-23 Applied Biosystems, Inc. 4,7-dichlorofluorescein dyes as molecular probes
US5654419A (en) 1994-02-01 1997-08-05 The Regents Of The University Of California Fluorescent labels and their use in separations
US5854033A (en) 1995-11-21 1998-12-29 Yale University Rolling circle replication reporter systems
US5800996A (en) 1996-05-03 1998-09-01 The Perkin Elmer Corporation Energy transfer dyes with enchanced fluorescence
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US6207392B1 (en) 1997-11-25 2001-03-27 The Regents Of The University Of California Semiconductor nanocrystal probes for biological applications and process for making and using such probes
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US6251303B1 (en) 1998-09-18 2001-06-26 Massachusetts Institute Of Technology Water-soluble fluorescent nanocrystals
US6426513B1 (en) 1998-09-18 2002-07-30 Massachusetts Institute Of Technology Water-soluble thiol-capped nanocrystals
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JP4567436B2 (ja) 2001-07-20 2010-10-20 ライフ テクノロジーズ コーポレーション 発光ナノ粒子およびそれらの調製方法
WO2007008221A2 (en) * 2004-08-10 2007-01-18 President And Fellows Of Harvard College DETECTION OF PHOSPHORYLATED eIF2α AS A DIAGNOSTIC TEST FOR EFFICIENCY AND SENSITVITY OF TRANSLATION INITIATION INHIBITORS IN THE TREATMENT OF CANCER AND OTHE R PROLIFERATIVE DISEASES
WO2008008333A2 (en) 2006-07-11 2008-01-17 President And Fellows Of Harvard College Bioassays for quality control of nutriceuticals that inhibit, upregulate or otherwise modulate translation initiation
CA2758546C (en) * 2009-04-17 2019-02-26 President And Fellows Of Harvard College Quality control bioassays for nutriceutical and medicinal products
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CN101671669B (zh) * 2009-08-27 2012-05-02 浙江大学 一种肝癌靶向性基因表达元件ae及其应用

Also Published As

Publication number Publication date
US20150301023A1 (en) 2015-10-22
CA2866175A1 (en) 2014-01-23
AU2013292266A1 (en) 2014-09-25
IN2014DN07866A (https=) 2015-04-24
RU2014136408A (ru) 2016-09-10
PE20142297A1 (es) 2014-12-19
CN104641231A (zh) 2015-05-20
WO2014015328A1 (en) 2014-01-23
US9952200B2 (en) 2018-04-24
DK2820418T3 (en) 2018-02-12
MA35924B1 (fr) 2014-12-01
CA2866175C (en) 2021-04-20
KR20150035496A (ko) 2015-04-06
EP2820418B1 (en) 2017-12-06
ES2656941T3 (es) 2018-03-01
CL2014002530A1 (es) 2015-01-09
JP6200501B2 (ja) 2017-09-20
PL2820418T3 (pl) 2018-05-30
MX356147B (es) 2018-05-15
KR102136763B1 (ko) 2020-08-13
NO2912013T3 (https=) 2018-03-10
EP2820418A1 (en) 2015-01-07
JP2015524269A (ja) 2015-08-24
RU2662358C2 (ru) 2018-07-25
PT2820418T (pt) 2018-02-12
AU2013292266B2 (en) 2019-01-03
MX2014012542A (es) 2014-11-21
CO7151536A2 (es) 2014-12-29
ZA201406653B (en) 2022-05-25
HUE036166T2 (hu) 2018-06-28

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Granted publication date: 20160907