CN104636618A - Radiotherapy treatment planning system - Google Patents
Radiotherapy treatment planning system Download PDFInfo
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- CN104636618A CN104636618A CN201510067495.4A CN201510067495A CN104636618A CN 104636618 A CN104636618 A CN 104636618A CN 201510067495 A CN201510067495 A CN 201510067495A CN 104636618 A CN104636618 A CN 104636618A
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Abstract
A radiotherapy treatment planning system comprises an input unit, a template library, a template matching unit and a radiotherapy treatment plan output unit, wherein the input unit is used for obtaining scanning images of marked tumor parts and primary radiotheraphy treatment planning information of the tumor parts, the template library is suitable for storing a plurality of radiotherapy treatment planning templates, the radiotherapy treatment plan information of different tumor parts is stored in the radiotherapy treatment planning templates, the template matching unit is suitable for selecting the corresponding radiotherapy treatment planning templates from the template library according to the obtained scanning images of the marked tumor parts and the primary radiotheraphy treatment planning information of the tumor parts and selecting the corresponding radiotherapy planning templates from the template library, and the radiotherapy treatment plan output unit is suitable for using the radiotherapy planning information obtained from the radiotherapy planning templates as the radiotherapy planning information of the tumor parts and outputting the radiotherapy planning information. According to the scheme, the configuration efficiency of the radiotherapy treatment scheme can be improved.
Description
Technical field
The present invention relates to medical treatment technical field, particularly relate to a kind of radiotherapy planning system.
Background technology
Radiation therapy utilizes modern high technology computing machine to control advanced ray generation equipment--medical computerized linear accelerator, do not operated on, no pain, damage are little, physique consumes little effective cancer immunotherapies by incident direction, the radioactive area controlling radioactive ray to tumour.Before carrying out radiation therapy, the radiotherapy treatment planning of each patient need be designed on computer workstation, while displaying tumour accepts radiation lethal exposure dosage, control around vital tissue and vitals by x radiation x dosage within the tolerance range of normal structure and organ.
In radiotherapy treatment planning, doctor needs to provide prescription and therapeutic scheme, physics teacher will according to doctor formula, delineate organ and knub position, and total gross tumor volume (Gross Tumor Volume, GTV), the target area such as planned treatment volume (Planning Target Volume, PTV) and clinical target volume (Clinical Target volume, CTV); Then according to therapeutic scheme, create launched field (Beam) and Ziye (Beam segment), check dose volume distribution (Dose-Volume Histogram, DVH), if do not meet prescription target, be optimized and calculate until meet the demands; Then ratify to plan (Approve), preserve whole planning data, in order to treatment.
Therefore, the determination of the radiotherapy planning information of the tumor locus in prior art in radiotherapy treatment planning, needs doctor and physics teacher to do a large amount of work, there is the problem of inefficiency.
Summary of the invention
What the embodiment of the present invention solved is the efficiency of configuration improving radiation treatment plan.
For solving the problem, embodiments provide a kind of radiotherapy planning system, described method comprises:
Input block, is suitable for obtaining the scan image of tumor locus through mark and the preliminary radiotherapy planning information of described tumor locus;
Template base, is suitable for storing multiple radiotherapy planning template, stores the radiotherapy planning information of different tumor locus in multiple described radiotherapy planning template;
Template matches unit, is suitable for, according to the obtained scan image of tumor locus through mark and the preliminary radiotherapy planning information of described tumor locus, choosing corresponding radiotherapy planning template from template base;
Radiotherapy planning output unit, is suitable for the radiotherapy planning information will obtained from described radiotherapy planning template, as described tumor locus radiotherapy planning information and export;
Alternatively, described system also comprises:
Analogue unit, is suitable for the radiotherapy planning information of information according to obtained described tumor locus and described tumor locus, simulates the Patients During Radiotherapy of described tumor locus and result and exports;
Adjustment unit, is suitable for, according to the radiotherapy planning result of obtained described tumor locus, adjusting the information of the radiotherapy planning of described tumor locus.
Alternatively, the radiotherapy planning information of described different tumor locus comprises the information of launched field and Ziye.
Alternatively, described analogue unit comprises:
Segmentation subelement, is suitable for from scan image, be partitioned into described tumor locus and other positions except described tumor locus;
Create subelement, be suitable for the information adopting the tumor locus be partitioned into, create the information of total gross tumor volume, and adopt the information of the radiotherapy planning of described tumor locus, create corresponding launched field and the information of Ziye;
Computation subunit, is suitable for the information adopting the launched field, Ziye and the described total gross tumor volume that create, calculates the information of dose volume distribution;
Result generation unit, is suitable for, according to the information of the dose volume distribution calculated, drawing the information of the radiotherapy planning result of described tumor locus;
Output display subelement, is suitable for the radiotherapy planning result of described tumor locus to carry out output display.
Alternatively, described radiotherapy planning system also comprises storage unit, be suitable for the information of memory point, described point is carry out with original resolution the point that stores in the described tumor locus of mark and the outline line at other positions described, and the curvature of the point stored is greater than default curvature threshold;
Described segmentation subelement comprises interpolation fitting module and segmentation module, wherein:
Described interpolation fitting module, is suitable for carrying out interpolation to stored point, simulates the outline line at described tumor locus and other positions described;
Described segmentation module, is suitable for the outline line according to the described tumor locus simulated and other positions described, splits described tumor locus and other positions described.
Alternatively, described segmentation module is suitable for adopting automatic window width and window level method, according to the outline line at the described tumor locus simulated and other positions described, splits described tumor locus and other positions described.
Compared with prior art, technical scheme of the present invention has following advantage:
Pass through the information of the preliminary radiotherapy planning of obtained tumor locus, corresponding radiotherapy planning template is chosen from template base, because described therapeutic scheme template comprises the information of the radiotherapy planning corresponding with the radiotherapy planning of described tumor locus, can according to the information of the corresponding typical case of the radiotherapy planning of described tumor locus, rapid development goes out the therapeutic scheme of described tumor locus, therefore, the allocative efficiency of tumor locus therapeutic scheme can be improved.
Further, by the information of the expection treatment results of described tumor locus, the radiotherapy planning information of described tumor locus is adjusted, the accuracy of the radiotherapy planning information of determined tumor locus can be improved.
Accompanying drawing explanation
Fig. 1 is the structural representation of a kind of radiotherapy planning system in the embodiment of the present invention;
Fig. 2 is the structural representation of the another kind of radiotherapy planning system in the embodiment of the present invention;
Fig. 3 is the schematic diagram passing through tumor locus and other positions marked of the use in the embodiment of the present invention;
Fig. 4 is the structural representation of the analogue unit in the embodiment of the present invention;
Fig. 5 is the DVH schematic diagram of the radiotherapy planning result of the tumor locus exported in the embodiment of the present invention.
Embodiment
In order to save human resources, raise the efficiency, in the embodiment of the present invention, pass through the information of the preliminary radiotherapy planning of obtained tumor locus, corresponding radiotherapy planning template is chosen from template base, because described therapeutic scheme template comprises the information of the radiotherapy planning corresponding with the radiotherapy planning of described tumor locus, can according to the information of the corresponding typical case of the radiotherapy planning of described tumor locus, rapid development goes out the therapeutic scheme of described tumor locus, the formulation efficiency of tumor locus therapeutic scheme can be improved, save human resources.
For enabling above-mentioned purpose of the present invention, feature and advantage more become apparent, and are described in detail specific embodiments of the invention below in conjunction with accompanying drawing.
Fig. 1 shows the structural representation of a kind of radiotherapy planning system in the embodiment of the present invention.Radiotherapy planning system 100 as shown in Figure 1, can comprise input block 101, template base 102, template matches unit 103 and radiotherapy planning output unit 104.Template matches unit 103 respectively with input block 101, template base 102 and radiotherapy planning output unit 104, wherein: input block 101, be suitable for obtain through mark the scan image of tumor locus and the preliminary radiotherapy planning information of described tumor locus.Template base 102, is suitable for storing multiple radiotherapy planning template, stores the radiotherapy planning information of different tumor locus in multiple described radiotherapy planning template.Template matches unit 103, is suitable for, according to the obtained scan image of tumor locus through mark and the preliminary radiotherapy planning information of described tumor locus, choosing corresponding radiotherapy planning template from template base.Radiotherapy planning output unit 104, is suitable for the radiotherapy planning information will obtained from described radiotherapy planning template, as described tumor locus radiotherapy planning information and export.
In concrete enforcement, the preliminary radiotherapy planning information of the tumor locus that input block 101 obtains can the preliminary radiotherapy planning information formulated of the classification of medical personnel located belonging to tumor locus, such as, 3 dimensional conformal radiation therapy (3D-CRT), static intensity modulating (step-and-shoot), draw fox to treat (Arc), and rotate volume intensity modulated radiation therapy etc.
Below the principle of work of the radiotherapy planning system in the present embodiment is further described in detail:
First, medical personnel located is at CT scan (the Computed Tomograp hy of patient, CT), nuclear magnetic resonance (magnetic resonance, or positron e mission computed tomography (Positron Emission Computed Tomography MR), etc. PET-CT) during impact checks, according to position and the size of priori determination tumor section, and store accordingly after corresponding mark being made to tumor section in scan image, medical personnel located can determine the preliminary radiotherapy planning information of tumor locus according to the position of tumor section and size etc. simultaneously.When needs time, the preliminary radiotherapy planning information of described tumor locus and the scan image of patient are input in the radiotherapy planning system in the embodiment of the present invention by input block 101 by medical personnel located by the image through mark.
The template of the information of the radiotherapy planning of various tumor locus is stored in template base 102, wherein, the information of the radiotherapy planning of the tumor locus stored in template base 102 is carried out classification according to the different therapeutic modality of tumor locus and is stored, by 3 dimensional conformal radiation therapy (3D-CRT), static intensity modulating (step-and-shoot), draw fox to treat (Arc), and rotate volume intensity modulated radiation therapy etc. as one-level index.Certainly, the template in template base 102 can also further segmentation, such as 3D-CRT template, can be subdivided into the template of four launched fields and seven wild templates etc.; ARC template, also can segment not 0 ~ 270 degree rotate forward template and 0 ~ 270 degree of retrograde rotation template etc.
The preliminary radiotherapy planning information of the tumor locus that template matches unit 103 is received by input block 101, just can by the radiotherapy planning template finding the corresponding radiotherapy planning of described tumor locus to match.Such as, when the preliminary radiotherapy planning information that input block 101 receives is 3 dimensional conformal radiation therapy, can one-level index be choose in template under the catalogue of 3 dimensional conformal radiation therapy to choose the radiotherapy planning template of mating most with in the position of described tumor locus, size etc. in template base 102.
Wherein, in template base 102, store energy and quantity that radiotherapy planning template comprises launched field and the Ziye used in radiotherapy planning process, and treat the information such as angle.The initialization of template creates and needs the concrete therapeutic scheme of tumor locus summarize and classify, and extracts committed step and obtains.
Fig. 2 shows the structural representation of the another kind of radiotherapy planning system in the embodiment of the present invention.Radiotherapy planning system 200 as shown in Figure 2, except comprising input block 201, template base 202, template matches unit 203 and radiotherapy planning output unit 204, also can comprise analogue unit 205 and adjustment unit 206, wherein: analogue unit 205 is connected with input block 201, template matches unit 203 and adjustment unit 206 respectively.
In concrete enforcement, analogue unit 205, is suitable for the radiotherapy planning information of information according to obtained described tumor locus and described tumor locus, simulates the Patients During Radiotherapy of described tumor locus and result and exports; Adjustment unit 206, is suitable for, according to the radiotherapy planning result of obtained described tumor locus, adjusting the information of the radiotherapy planning of described tumor locus.
Below the principle of work of the radiotherapy planning system in the present embodiment is further described in detail:
When template matches unit 203 matches corresponding radiotherapy planning template from template base 202, analogue unit 205 just can obtain corresponding radiotherapy planning information from the radiotherapy planning template matched, as the information of launched field, Ziye and treatment angle, obtain the information of the current tumor locus that input block 201 inputs simultaneously, the Patients During Radiotherapy of current tumor locus is emulated, and the radiotherapy planning result simulating the current cancer position drawn is exported in the mode of chart.Therefore, the radiotherapy planning result exported by analogue unit 205, the radiotherapy planning result adopting adjustment unit 206 to be exported by analogue unit 205 and the radiotherapy planning result of expection compare, adjust with the information of the radiotherapy planning to described tumor locus, as adjusted etc. launched field, Ziye and treatment angle, to reach the radiotherapy planning result met the demands.
In concrete enforcement, radiotherapy planning system in the present embodiment also comprises storage unit 207, be suitable for the information of memory point, described point is carry out with original resolution the point that stores in the described tumor locus of mark and the outline line at other positions described, and the curvature of the point stored is greater than default curvature threshold.Shown in Figure 3, the outline line at tumor locus wherein and other positions described is that medical personnel located is gained knowledge according to human dissection and Computer Image Processing method is automatically delineated and drawn.Like this, when storing the outline line of tumor locus and other positions except tumor locus, the information of branch in the middle part of the outline line that only can store tumor locus and other positions except tumor locus, therefore, saves storage resources.
Fig. 4 shows the structural representation of a kind of analogue unit in the embodiment of the present invention.Analogue unit 400 as shown in Figure 4 can comprise: segmentation subelement 401, establishment subelement 402, computation subunit 403, result generation unit 404 and output display subelement 405, wherein: segmentation subelement 401, is suitable for from scan image, be partitioned into described tumor locus and other positions except described tumor locus; Create subelement 402, be suitable for the information adopting the tumor locus be partitioned into, create the information of total gross tumor volume (GTV), and adopt the information of the radiotherapy planning of described tumor locus, create corresponding launched field and the information of Ziye; Computation subunit 403, is suitable for the information adopting the launched field, Ziye and the described total gross tumor volume (GTV) that create, calculates the information of dose volume distribution (DVH); Result generation unit 404, is suitable for, according to the information of the dose volume distribution calculated, drawing the information of the radiotherapy planning result of described tumor locus; Output display subelement 405, is suitable for the radiotherapy planning result of described tumor locus to carry out output display.
In concrete enforcement, in order to other positions outside tumor locus and tumour are split exactly, segmentation subelement 401 in the embodiment of the present invention can also comprise interpolation fitting module 4011 and segmentation module 4012, wherein: interpolation fitting module 4011, the point be suitable for storing in storage unit 207 carries out interpolation, simulates the outline line at described tumor locus and other positions described; Segmentation module 4012, is suitable for the outline line according to the described tumor locus simulated and other positions described, splits described tumor locus and other positions described.Wherein, segmentation module 4012 is suitable for adopting automatic window width and window level method, according to the outline line at the described tumor locus simulated and other positions described, splits described tumor locus and other positions described.
The principle of work of the analogue unit 400 in the present embodiment is:
Interpolation fitting module 4011 in segmentation subelement 401 obtains in the outline line at described tumor locus through marking and other positions described from storage unit carries out with original resolution the point that stores, and interpolation is carried out to the point stored in storage unit, simulate the outline line at described tumor locus and other positions described.Afterwards, segmentation module 4012, according to the outline line at the described tumor locus simulated and other positions described, is split described tumor locus and other positions described.Wherein, described segmentation module 4012, based on image grey level histogram distribution, is found out the separatrix of organ, for the organ that the contrast such as skin and lung is obvious, can be reached reasonable segmentation effect; For the unconspicuous organ of contrast such as heart, prostate etc., automatic window width and window level can be adopted to split, to reduce the appearance of the situation of " leak and divide " and " wrong point ".
After segmentation subelement 401 is partitioned into described tumor locus and other positions except described tumor locus, create the information that subelement 402 adopts the tumor locus be partitioned into, create the information of total gross tumor volume (GTV), and adopt the information of the radiotherapy planning of described tumor locus, create corresponding launched field and the information of Ziye.Then, computation subunit 403 adopts the information of launched field, Ziye and the described total gross tumor volume (GTV) created, and calculates the information of dose volume distribution (DVH).Specifically, computation subunit 403 is using the knub position tentatively determined and size as input parameter, and determining the locus of tumor locus in patient body and size, is the cube of a standard, as the boundary constraint scope of GTV.Then, utilize the edge extracting in Computer Image Processing and image segmentation further, by other organs removing in tumor section, obtain a relatively level and smooth shape like this, as tumor locus.Wherein, tumor center's coordinate (x, y, z) can tentatively be determined according to the position of tumor locus in the position of tumor section.The size of tumor locus is then tumour reference three-dimensional dimension, such as length is respectively 5mm, 5mm and 10mm.
Then, result generation unit 404 is according to the information of dose volume distribution (DVH) calculated, draw the information of the radiotherapy planning result of described tumor locus, and by output display subelement 405, the radiotherapy planning result of described tumor locus is carried out output display.Refer to Fig. 4, the analogue unit 205 that wherein output display subelement 405 exports simulates the information of the radiotherapy planning result of the described tumor locus drawn.
One of ordinary skill in the art will appreciate that all or part of step in the various methods of above-described embodiment is that the hardware that can carry out instruction relevant by program has come, this program can be stored in computer-readable recording medium, and storage medium can comprise: ROM, RAM, disk or CD etc.
Done detailed introduction to the method and system of the embodiment of the present invention above, the present invention is not limited to this.Any those skilled in the art, without departing from the spirit and scope of the present invention, all can make various changes or modifications, and therefore protection scope of the present invention should be as the criterion with claim limited range.
Claims (6)
1. a radiotherapy planning system, is characterized in that, comprising:
Input block, is suitable for obtaining the scan image of tumor locus through mark and the preliminary radiotherapy planning information of described tumor locus;
Template base, is suitable for storing multiple radiotherapy planning template, stores the radiotherapy planning information of different tumor locus in multiple described radiotherapy planning template;
Template matches unit, is suitable for, according to the obtained scan image of tumor locus through mark and the preliminary radiotherapy planning information of described tumor locus, choosing corresponding radiotherapy planning template from template base;
Radiotherapy planning output unit, is suitable for the radiotherapy planning information will obtained from described radiotherapy planning template, as described tumor locus radiotherapy planning information and export.
2. radiotherapy planning system according to claim 1, is characterized in that, also comprise:
Analogue unit, is suitable for the radiotherapy planning information of information according to obtained described tumor locus and described tumor locus, simulates the Patients During Radiotherapy of described tumor locus and result and exports;
Adjustment unit, is suitable for, according to the radiotherapy planning result of obtained described tumor locus, adjusting the information of the radiotherapy planning of described tumor locus.
3. radiotherapy planning system according to claim 1 and 2, is characterized in that, the radiotherapy planning information of described different tumor locus comprises the information of launched field and Ziye.
4. radiotherapy planning system according to claim 3, is characterized in that, described analogue unit comprises:
Segmentation subelement, is suitable for from scan image, be partitioned into described tumor locus and other positions except described tumor locus;
Create subelement, be suitable for the information adopting the tumor locus be partitioned into, create the information of total gross tumor volume, and adopt the information of the radiotherapy planning of described tumor locus, create corresponding launched field and the information of Ziye;
Computation subunit, is suitable for the information adopting the launched field, Ziye and the described total gross tumor volume that create, calculates the information of dose volume distribution;
Result generation unit, is suitable for, according to the information of the dose volume distribution calculated, drawing the information of the radiotherapy planning result of described tumor locus;
Output display subelement, is suitable for the radiotherapy planning result of described tumor locus to carry out output display.
5. radiotherapy planning system according to claim 4, it is characterized in that, described radiotherapy planning system also comprises storage unit, be suitable for the information of memory point, described point is carry out with original resolution the point that stores in the described tumor locus of mark and the outline line at other positions described, and the curvature of the point stored is greater than default curvature threshold;
Described segmentation subelement comprises interpolation fitting module and segmentation module, wherein:
Described interpolation fitting module, is suitable for carrying out interpolation to stored point, simulates the outline line at described tumor locus and other positions described;
Described segmentation module, is suitable for the outline line according to the described tumor locus simulated and other positions described, splits described tumor locus and other positions described.
6. radiotherapy planning system according to claim 5, it is characterized in that, described segmentation module is suitable for adopting automatic window width and window level method, according to the outline line at the described tumor locus simulated and other positions described, splits described tumor locus and other positions described.
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| CN107229830A (en) * | 2017-06-01 | 2017-10-03 | 上海联影医疗科技有限公司 | Radiotherapy planning system and its task executing method |
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| CN108922589A (en) * | 2018-06-28 | 2018-11-30 | 上海联影医疗科技有限公司 | A kind of radiotherapy planning display system and storage medium |
| CN109276819A (en) * | 2017-07-20 | 2019-01-29 | 株式会社东芝 | Information processing unit, information processing system and storage medium |
| CN111803104A (en) * | 2020-07-20 | 2020-10-23 | 上海市第六人民医院 | Medical image display method, medium and electronic equipment |
| WO2021143019A1 (en) * | 2020-01-14 | 2021-07-22 | 平安科技（深圳）有限公司 | Image search method and apparatus based on artificial intelligence, device, and medium |
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107229830A (en) * | 2017-06-01 | 2017-10-03 | 上海联影医疗科技有限公司 | Radiotherapy planning system and its task executing method |
| CN109276819A (en) * | 2017-07-20 | 2019-01-29 | 株式会社东芝 | Information processing unit, information processing system and storage medium |
| CN108744313A (en) * | 2018-06-25 | 2018-11-06 | 西安大医数码科技有限公司 | Radiotherapy planning planing method, radiotherapy planning system and radiotherapy system |
| CN108922589A (en) * | 2018-06-28 | 2018-11-30 | 上海联影医疗科技有限公司 | A kind of radiotherapy planning display system and storage medium |
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| WO2021143019A1 (en) * | 2020-01-14 | 2021-07-22 | 平安科技（深圳）有限公司 | Image search method and apparatus based on artificial intelligence, device, and medium |
| CN111803104A (en) * | 2020-07-20 | 2020-10-23 | 上海市第六人民医院 | Medical image display method, medium and electronic equipment |
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