CN108922589B - Radiotherapy plan display system and storage medium - Google Patents
Radiotherapy plan display system and storage medium Download PDFInfo
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- CN108922589B CN108922589B CN201810691565.7A CN201810691565A CN108922589B CN 108922589 B CN108922589 B CN 108922589B CN 201810691565 A CN201810691565 A CN 201810691565A CN 108922589 B CN108922589 B CN 108922589B
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Abstract
The embodiment of the invention discloses a radiotherapy plan display system and a storage medium. The system comprises: the data acquisition device is used for acquiring an original image sequence distributed at a first time and original radiotherapy plan execution control point data distributed at a second time; the fusion device is used for executing control point data according to the original image sequence and the original radiotherapy plan, determining a target image sequence and a target dose distribution sequence, and fusing the target image sequence and the target dose distribution sequence to obtain a plan display image sequence; the display device is used for displaying the planned display image sequence. Through the technical scheme, the target dose distribution sequence of plan radiotherapy corresponding to each time point of the radiotherapy plan is displayed in the image sequence corresponding to the time point before the radiotherapy plan is executed, and the information of each intermediate plan link of the radiotherapy plan is displayed in a more intuitive, more accurate and detailed mode, so that powerful data support is provided for a treating physician to adjust the radiotherapy plan.
Description
Technical Field
The embodiment of the invention relates to a medical image processing technology, in particular to a radiotherapy plan display system and a storage medium.
Background
Radiation therapy (abbreviated as radiotherapy) is an effective treatment method for tumor and cancer, and before radiotherapy is performed on a patient, a treating physician usually makes a radiotherapy plan suitable for the patient, which roughly comprises the following steps: and acquiring a three-dimensional image of a body part corresponding to a diseased organ of a patient, and making a radiotherapy plan based on the three-dimensional image.
In order to understand the treatment effect of the planned radiotherapy plan before the radiotherapy plan is executed, the cumulative dose distribution corresponding to the whole radiotherapy plan is usually displayed in the three-dimensional image or the four-dimensional image of the patient in the radiotherapy planning system. However, the conventional display method of the radiotherapy plan can only make the treating physician know the final treatment effect of the whole radiotherapy plan, but cannot know more detailed treatment condition of the radiotherapy plan.
Disclosure of Invention
Embodiments of the present invention provide a radiotherapy plan display system and a storage medium, so as to display the treatment effect of a radiotherapy plan more intuitively and in detail, thereby providing a more accurate and detailed radiotherapy plan information for a treating physician.
In a first aspect, an embodiment of the present invention provides a radiotherapy plan display system, including:
the data acquisition device is used for acquiring an original image sequence distributed at a first time and original radiotherapy plan execution control point data distributed at a second time, wherein the original image sequence and the original radiotherapy plan execution control point data correspond to the same object;
the fusion device is used for executing control point data according to the original image sequence and the original radiotherapy plan, determining a target image sequence and a target dose distribution sequence, and fusing the target image sequence and the target dose distribution sequence to obtain a plan display image sequence;
and the display device is used for displaying the planned display image sequence.
In a second aspect, embodiments of the present invention also provide a storage medium containing computer-executable instructions, which when executed by a computer processor, are configured to perform operations comprising:
acquiring an original image sequence distributed at a first time and original radiotherapy plan execution control point data distributed at a second time, wherein the original image sequence and the original radiotherapy plan execution control point data correspond to the same object;
executing control point data according to the original image sequence and the original radiotherapy plan, determining a target image sequence and a target dose distribution sequence, and fusing the target image sequence and the target dose distribution sequence to obtain a plan display image sequence;
and displaying the planned display image sequence.
In the embodiment of the invention, an original image sequence distributed along with time and original radiotherapy plan execution control point data distributed along with time of the same object are obtained through a data acquisition device in a radiotherapy plan display system; the fusion device executes control point data according to the original image sequence and the original radiotherapy plan, determines a target image sequence and a target dose distribution sequence, and fuses the target image sequence and the target dose distribution sequence to obtain a plan display image sequence; the display device displays the planned display image sequence. Before the radiotherapy plan is executed, the target dose distribution sequence of plan radiotherapy corresponding to each time point of the radiotherapy plan is displayed in the image sequence corresponding to the time point, and the information of each intermediate plan link of the radiotherapy plan is displayed in a more intuitive, more accurate and detailed mode, so that powerful data support is provided for a treating physician to adjust the radiotherapy plan.
Drawings
Fig. 1 is a schematic structural diagram of a radiotherapy plan display system according to a first embodiment of the present invention;
fig. 2 is a schematic structural diagram of a radiotherapy plan display system in the second embodiment of the present invention.
Detailed Description
The present invention will be described in further detail with reference to the accompanying drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not limiting of the invention. It should be further noted that, for the convenience of description, only some of the structures related to the present invention are shown in the drawings, not all of the structures.
The radiotherapy plan display system provided by the embodiment of the invention is suitable for making a radiotherapy plan for a patient, and before the radiotherapy plan is executed, the predictive radiotherapy results corresponding to each intermediate link in the radiotherapy plan are displayed, and the radiotherapy plan display system is particularly suitable for a thoracoabdominal focus treatment scene. In the embodiments of the present invention, the focus of the chest and abdomen will be described as an example.
In the process of performing Computed Tomography (CT) scanning or Magnetic Resonance (MR) scanning on a patient with a thoracoabdominal lesion, the respiratory motion of the patient may cause the spatial position of each tissue organ and tumor in the body to change, so that the acquired CT image or MR image of the thoracoabdominal lesion may not reflect the actual position of all the tissue organs and tumors during the treatment process. Then, the radiotherapy plan based on the CT image or MR image may be biased to be unfavorable for the subsequent radiotherapy. Therefore, in the embodiment of the present invention, a series of patient image data (i.e., an original image sequence, which is a plurality of patient images arranged in time sequence and may be referred to as a four-dimensional image because of having time information) within a certain time period before radiotherapy is acquired, and the original image sequence can reflect the position change of organs and tumors caused by respiratory movement of a patient. Then, according to each time point, the predictive radiotherapy result (such as dose distribution, also called as planning radiotherapy result) of the intermediate link of the formulated radiotherapy plan is displayed in the corresponding patient image. Therefore, the treating physician can more intuitively observe the real-time change process of the formulated radiotherapy plan in the simulated treatment process, and data support is provided for the formulated more accurate radiotherapy plan.
Example one
Fig. 1 is a schematic structural diagram of a radiotherapy plan display system provided in this embodiment, and in this embodiment, a radiotherapy plan display system 100 is provided, where the radiotherapy plan display system 100 includes: the data acquisition device 110, the fusion device 120 and the display device 130 are in communication connection with each other, wherein the data acquisition device 110 is used for acquiring an original image sequence distributed at a first time and original radiotherapy plan execution control point data distributed at a second time, and the original image sequence and the original radiotherapy plan execution control point data correspond to the same object; a fusion device 120, configured to execute control point data according to the original image sequence and the original radiotherapy plan acquired by the data acquisition device 110, determine a target image sequence and a target dose distribution sequence, and fuse the target image sequence and the target dose distribution sequence to obtain a plan display image sequence; and the display device 130 is used for displaying the planned display image sequence acquired by the fusion device.
The communication connection may be through a wire or through a bus, which may include one or more of several types of bus structures, such as a data bus, a control bus, an expansion bus, or a local bus using any of a variety of bus structures. By way of example, such architectures include, but are not limited to, Industry Standard Architecture (ISA) bus, micro-channel architecture (MAC) bus, enhanced ISA bus, Video Electronics Standards Association (VESA) local bus, and Peripheral Component Interconnect (PCI) bus. The first time distribution refers to the distribution of each time point in the original image sequence. The second time distribution refers to the distribution of each time point in the control point data for executing the original radiotherapy plan. The time points in the first time distribution and the second time distribution may be the same or different.
The radiotherapy plan execution control point data is control data for controlling the radiotherapy apparatus to execute a radiotherapy plan, and may be data such as a rotation angle of a treatment head of the radiotherapy apparatus, a shape formed by a multi-leaf grating (multi-leaf grating shape), a shape formed by a tungsten gate (tungsten gate shape), a radiation jump number, and a radiation dose rate. The original radiotherapy plan execution control point data refers to radiotherapy plan execution control point data obtained when the radiotherapy plan is made. Illustratively, the data obtaining means 110 comprises an original control point data obtaining module for: determining preset control point data of a radiotherapy plan according to a plan image corresponding to the object; and acquiring the data of the control point of the execution of the original radiotherapy plan based on a track generation algorithm according to the preset control point data. Wherein, the object refers to the radiation object of radiotherapy planning, i.e. patient or patient. The planning image refers to an image of a patient for planning radiotherapy, such as a CT image or an MR image, which may be a three-dimensional image or a four-dimensional image. The preset control point data refers to control point data set in a primarily formulated radiotherapy plan. The trajectory generation algorithm may also be referred to as a control point conversion algorithm or a motion fitting algorithm, which is an algorithm for performing constraint-based fitting on preset control point data to obtain control point data corresponding to a smooth therapeutic head motion trajectory. That is, the original control point data obtaining module first obtains preset control point data preset when a radiotherapy plan is made according to a plan image of a patient, and generates original radiotherapy plan execution control point data by using the preset control point data as basic data and applying a trajectory generation algorithm so as to obtain control point data with higher accuracy and higher data intensity. For example, the preset control point data are radiation control data with treatment head rotation angles of 10 °, 25 °, 40 ° and 60 °, respectively, and a plurality of control point data with rotation angles of 1 ° at a more dense interval are obtained from the preset control point data, and the plurality of control point data with rotation angles of 1 ° perform control point data for the original radiotherapy plan.
The target image sequence refers to an image sequence for performing a fusion operation, wherein each image corresponds to a time point corresponding to the fusion operation (i.e., a fusion time point). The target dose distribution sequence refers to a dose distribution sequence for performing a fusion operation, wherein each dose distribution corresponds to a fusion time point corresponding to the fusion operation. The dose distribution at each fusion time point needs to be determined from the planning image and the radiotherapy plan execution control point data corresponding to the fusion time point. The plan display image is an image for displaying a radiotherapy plan result at a certain fusion time point. The planned display video sequence is a plurality of planned display videos arranged at a plurality of fusion time points. The fusion time point is the trigger time for displaying the radiotherapy plan, namely, when a certain fusion time point is reached, the radiotherapy plan corresponding to the fusion time point is displayed. Therefore, the fusion time point is the time mark for acquiring the target image sequence and the target radiotherapy plan execution control point data. The fusion time point may be determined according to the time information in the first time distribution and the second time distribution, for example, each time point in the time distribution with smaller time granularity in the first time distribution and the second time distribution, or each time point in the time distribution corresponding to the data with higher data precision in the original image sequence and the original radiotherapy plan execution control point data; the fusion time point may also be a plurality of time points set by the user according to the user's own needs, for example, each time point is determined by the user according to the intermediate link information of the radiotherapy plan that the user needs to know.
Specifically, since the radiotherapy plan display system provided by the embodiment of the present invention is used for performing more intuitive stage display on the planned treatment effect, when the radiotherapy plan display system 100 operates, the necessary basic data for generating the plan display image sequence, that is, the original image sequence for carrying the planned treatment result (i.e., dose distribution) and the original radiotherapy plan execution control point data for determining the planned radiotherapy result, are first acquired by the data acquisition device 110. The original image sequence may be obtained by performing a radiation scan on the patient for a predetermined period of time, and the original radiotherapy plan execution control point data may be obtained by preparing a radiotherapy plan based on the planning image of the patient. After acquiring the required basic data, the data acquisition device 110 transmits the original image sequence and the original radiotherapy plan execution control point data to the fusion device 120. The fusion device 120 determines a target image sequence and target radiotherapy plan execution control point data corresponding to each other at each time point according to the received original image sequence and original radiotherapy plan execution control point data, and then determines a corresponding target dose distribution sequence from the target radiotherapy plan execution control point data and the patient plan image. Then, the target image sequence and the target dose distribution sequence are fused according to the corresponding time points to obtain a planning display image sequence which can be displayed in the radiotherapy plan, and the planning display image sequence is transmitted to the display device 130. The display device 130 displays the planned display image sequence in accordance with the display request. It should be noted that the display format here may be a two-dimensional or three-dimensional display format. In the case of a two-dimensional display, the fusion process is to fuse the target dose distribution into the target image in the form of two-dimensional slices. If the target image sequence is in a three-dimensional display form, fusing each two-dimensional slice image in the target image sequence with the corresponding two-dimensional slice dose distribution in the target dose distribution in the fusion process to obtain a plurality of two-dimensional fusion results; and obtaining a three-dimensional fusion result through three-dimensional reconstruction according to the plurality of two-dimensional fusion results, and displaying the three-dimensional fusion result.
Illustratively, the fusion device 120 includes: a fusion time point determining module 121, configured to determine a current fusion time point; a target image determining module 122, configured to determine, according to the original image sequence, a current target image corresponding to the current fusion time point determined by the fusion time point determining module 121; a target dose distribution determining module 123, configured to execute the control point data according to the original radiotherapy plan, and determine a current target dose distribution corresponding to the current fusion time point determined by the fusion time point determining module 121; a fusion module 124, configured to fuse the current target image determined by the target image determining module 122 and the current target dose distribution determined by the target dose distribution determining module 123, and obtain a current planned display image corresponding to the current fusion time point determined by the fusion time point determining module 121; and the loop module 125 is configured to update the next fusion time point to the current fusion time point after the current planned display image is obtained, and trigger the execution of the target image determination module 122 and the target dose distribution determination module 123 until the current fusion time point is the last fusion time point.
The current fusion time point is a fusion time point at which the planned display video generation processing is being performed. The current target image is a patient image corresponding to the current fusion time point, and may be an image directly obtained from the original image sequence, or an image obtained by performing setting processing such as preprocessing or interpolation on at least one image in the original image sequence. The current target dose distribution is a dose distribution corresponding to the current fusion time point, which may be a dose distribution at a single time point or an accumulated dose distribution at a plurality of time points before the current fusion time point. The current planned display image is the planned display image corresponding to the current fusion time point.
The process of acquiring the planned display image sequence by the fusion device 120 is cyclically operated according to a single fusion time point. In specific implementation, the fusion time point determining module 121 selects one fusion time point from the multiple fusion time points as a starting time point of the fusion operation, where the selected fusion time point is a current fusion time point, and then sends the current fusion time point to the target image determining module 122 and the target dose distribution determining module 123. The target image determining module 122 obtains a current target image from the original image sequence according to the obtained current fusion time point, and sends the current target image to the fusion module 124. The target dose distribution determining module 123 determines radiotherapy plan execution control point data corresponding to the current fusion time point (i.e., current target radiotherapy plan execution control point data) from the original radiotherapy plan execution control point data according to the obtained current fusion time point. Then, according to the data of the control point executed by the current target radiotherapy plan and the plan image corresponding to the current fusion time point according to which the radiotherapy plan is formulated, the current target dose distribution is determined, and the current target dose distribution is sent to the fusion module 124. The fusion module 124 fuses the received current target image and the current target dose distribution to superimpose the current target dose distribution on the current target image, so as to obtain a current plan display image, and triggers the execution of the loop module 125. The loop module 125 determines a next fusion time point after the current fusion time point from the plurality of fusion time points as a new current fusion time point, and triggers the target image determination module 122, the target dose distribution determination module 123 and the subsequent modules to execute. And circularly triggering and executing each module according to the process until the current fusion time point is the last fusion time point, and finishing the execution of each subsequent module, wherein the acquired plurality of current plan display images are arranged according to the plurality of fusion time points, so that the plan display image sequence is formed. Therefore, the information of each intermediate plan link of the radiotherapy plan can be acquired more automatically, and the application convenience of the radiotherapy plan display system is improved.
According to the technical scheme of the embodiment, an original image sequence distributed along with time and original radiotherapy plan execution control point data distributed along with time of the same object are obtained through a data acquisition device in a radiotherapy plan display system; the fusion device executes control point data according to the original image sequence and the original radiotherapy plan, determines a target image sequence and a target dose distribution sequence, and fuses the target image sequence and the target dose distribution sequence to obtain a plan display image sequence; the display device displays a sequence of planned display images. Before the radiotherapy plan is executed, the target dose distribution sequence of plan radiotherapy corresponding to each time point of the radiotherapy plan is displayed in the image sequence corresponding to the time point, and the information of each intermediate plan link of the radiotherapy plan is displayed in a more intuitive, more accurate and detailed mode, so that powerful data support is provided for a treating physician to adjust the radiotherapy plan.
Example two
Fig. 2 is a schematic structural diagram of a radiotherapy plan display system provided in this embodiment, which is based on the first embodiment and is not repeated in this embodiment for explaining the same or corresponding devices and terms as those in the first embodiment.
Referring to fig. 2, on the basis of the first embodiment, the target image determining module 122 in the present embodiment includes: a first time point querying unit 1221, configured to query whether there is a current fusion time point in the first time distribution; a first image obtaining unit 1222, configured to obtain, when a current fusion time point exists in the first time distribution, an image corresponding to the current fusion time point in the original image sequence as a current target image; the second image obtaining unit 1223 is configured to, when the current fusion time point does not exist in the first time distribution, interpolate to obtain a current target image according to the current fusion time point and the original image sequence.
Specifically, when the target image determining module 122 acquires the current target image, the first time point querying unit 1221 is triggered to be executed first, so as to determine whether the current fusion time point exists in the first time distribution corresponding to the original image sequence. If the first time point query unit 1221 determines that the current fusion time point exists in the first time distribution, indicating that the current target image exists in the original image sequence, the first image obtaining unit 1222 may be directly triggered to determine the image data corresponding to the current fusion time point in the original image sequence as the current target image. If the first time point query unit 1221 determines that the current fusion time point does not exist in the first time distribution, which indicates that the current target image does not exist in the original image sequence, the second image acquisition unit 1223 needs to be triggered to perform image interpolation according to the current fusion time point and the original image sequence to obtain the current target image.
Exemplarily, the second image acquisition unit 1223 is specifically configured to: respectively acquiring a first image corresponding to a first time point before the current fusion time point and a second image corresponding to a second time point after the current fusion time point from the original image sequence; determining an image characteristic change trend according to the first image and the second image; and taking the image characteristic change trend as an image interpolation constraint, and interpolating the first image and the second image according to the first time point, the current fusion time point and the second time point to obtain the current target image.
The first time point and the second time point refer to a previous fusion time point and a subsequent fusion time point which are closest to the current fusion time point in the first time distribution, respectively. The first image is an image corresponding to the first time point in the original image sequence. The second image is an image corresponding to the second time point in the original image sequence. The image characteristic variation trend refers to a variation trend of the same image characteristic between two images, for example, in two chest CT images, the position of a part of an organ in the two images is changed due to respiratory motion of a patient, or a tumor in the image after radiotherapy is smaller than that in the image before radiotherapy, and the position variation direction or the tumor reduction trend is the image characteristic variation trend.
Specifically, when the second image obtaining unit 1223 interpolates images in the original image sequence to obtain the current target image, two images required for interpolation need to be obtained first, and the process is as follows: first, determining two fusion time points, namely a first time point and a second time point, which are the two fusion time points before and after the first time distribution and are closest to the current fusion time point, and then respectively acquiring a first image and a second image corresponding to the first time point and the second time point in an original image sequence.
Then, the second image obtaining unit 1223 interpolates the first image and the second image according to the first time point, the current fusion time point, the second time point, the first image and the second image, and obtains a current target image. Namely, the first time point, the current fusion time point and the second time point are utilized to determine the numerical value interpolation proportion during image interpolation, and the interpolation proportion is utilized to interpolate the first image and the second image to obtain the current target image. Therefore, the current target image can be obtained by utilizing the front image and the rear image, and the precision of the current target image is improved. The process specifically comprises the following steps: the second image obtaining unit 1223 obtains an image feature variation trend between the two images according to the first image and the second image. And then, taking the image characteristic change trend as an interpolation constraint condition of subsequent image interpolation, and carrying out constrained interpolation on the first image and the second image by utilizing the interpolation proportion determined by the first time point, the current fusion time point and the second time point to obtain the current target image. Therefore, a more accurate interpolation result can be obtained, so that the image of the patient bearing the plan radiotherapy result is more accurate, and the display precision of the radiotherapy plan is further improved.
On the basis of the above technical solution, the target dose distribution determining module 123 in this embodiment includes: a target control point data determining unit 1231, configured to determine, according to the original radiotherapy plan execution control point data, current target radiotherapy plan execution control point data corresponding to the current fusion time point; a target dose distribution determining unit 1232, configured to execute the control point data and the planning image according to the target radiotherapy plan, and determine a current target dose distribution.
Specifically, when determining the current target dose distribution, the target dose distribution determining module 123 triggers the execution target control point data determining unit 1231 to execute the control point data according to the original radiotherapy plan, and acquire the execution control point data of the current target radiotherapy plan. This is because the dose distribution is calculated from the radiotherapy plan execution control point data and the plan image, and if the second time distribution does not have the current fusion time point, the original radiotherapy plan execution control point data needs to be interpolated to obtain the current target radiotherapy plan execution control point data. And then triggering the execution target dose distribution determining unit 1232 to calculate the current target dose distribution according to the data of the current target radiotherapy plan execution control point and the plan image, so as to obtain a more accurate dose distribution result.
Illustratively, the target control point data determining unit 1231 includes: a second time point query subunit, configured to query whether there is a current fusion time point in the second time distribution; a first control point data obtaining subunit, configured to, when a current fusion time point exists in the second time distribution, obtain radiotherapy plan execution control point data corresponding to the current fusion time point in the original radiotherapy plan execution control point data, as current target radiotherapy plan execution control point data; and the second control point data acquisition subunit is used for executing the control point data according to the current fusion time point and the original radiotherapy plan when the current fusion time point does not exist in the second time distribution, and interpolating to acquire the current target radiotherapy plan execution control point data.
Specifically, when obtaining the data of the control point executed by the current target radiotherapy plan, the target control point data determining unit 1231 triggers the second time point query subunit to be executed first, so as to determine whether the current fusion time point exists in the second time distribution corresponding to the data of the control point executed by the original radiotherapy plan. If the second time point query subunit determines that the current fusion time point exists in the second time distribution, it indicates that the current target radiotherapy plan execution control point data exists in the original radiotherapy plan execution control point data, and the first control point data acquisition subunit can be directly triggered to execute, so as to determine the radiotherapy plan execution control point data corresponding to the current fusion time point in the original radiotherapy plan execution control point data as the current target radiotherapy plan execution control point data. If the second time point query subunit determines that the current fusion time point does not exist in the second time distribution, the second time point query subunit indicates that the current target radiotherapy plan execution control point data does not exist in the original radiotherapy plan execution control point data, and the second control point data acquisition subunit needs to be triggered to execute, so that the interpolation of the radiotherapy plan execution control point data is performed according to the current fusion time point and the original radiotherapy plan execution control point data, and the current target radiotherapy plan execution control point data is acquired.
Further, the second control point data obtaining subunit is specifically configured to: respectively acquiring first radiotherapy plan execution control point data corresponding to a third time point before the current fusion time point and second radiotherapy plan execution control point data corresponding to a fourth time point after the current fusion time point from the original radiotherapy plan execution control point data; and interpolating the data of the first radiotherapy plan execution control point and the data of the second radiotherapy plan execution control point according to the third time point, the current fusion time point and the fourth time point to obtain data of the current target radiotherapy plan execution control point.
The third time point and the fourth time point respectively refer to a previous fusion time point and a subsequent fusion time point which are closest to the current fusion time point in the second time distribution.
Specifically, when the second control point data obtaining subunit interpolates the radiotherapy plan execution control point data to obtain the current target radiotherapy plan execution control point data, first determining two fusion time points, namely a third time point and a fourth time point, before and after the second time distribution is closest to the current fusion time point, and then obtaining first radiotherapy plan execution control point data and second radiotherapy plan execution control point data corresponding to the third time point and the fourth time point in the original radiotherapy plan execution control point data respectively. And then, determining a numerical value interpolation proportion when the radiotherapy plan executes the interpolation of the control point data by using the third time point, the current fusion time point and the fourth time point, and interpolating the first radiotherapy plan execution control point data and the second radiotherapy plan execution control point data by using the numerical value interpolation proportion to obtain the current target radiotherapy plan execution control point data. Therefore, the data of the control point for executing the current target radiotherapy plan can be obtained by utilizing the data of the front control point and the back control point, and the precision of the data of the control point for executing the current target radiotherapy plan is improved, so that the precision of dose distribution is further improved, and the precision of radiotherapy plan display is further improved.
Exemplarily, the target dose distribution determining unit 1232 is specifically configured to: and when the planning image is a four-dimensional planning image, determining the current target dose distribution according to the control point data executed by the current target radiotherapy plan and the planning image corresponding to the current fusion time point in the four-dimensional planning image.
Specifically, as before, the determination of the dose distribution requires the planning image as the calculated reference image. If the planning image is a three-dimensional image, the three-dimensional image is used as a reference image no matter whether the current fusion time point corresponding to the data of the execution control point of the current target radiotherapy plan corresponds to the time point of the three-dimensional image. When the planning image is a four-dimensional image, the calculation of the current target dose distribution needs to determine a three-dimensional image from the four-dimensional image, which is closer to the current fusion time point, and then calculate the dose distribution by using the three-dimensional image as a reference image. In this way a more accurate dose distribution can be obtained.
Further, the target dose distribution determining unit 1232 is specifically configured to: and determining the current target dose distribution according to the treatment head rotation angle, the multi-leaf grating shape, the tungsten gate shape, the treatment bed position, the radiation jump number and the radiation dose rate in the plan image and the execution control point data of the current target radiotherapy plan. Specifically, the determination process of the current target dose distribution is performed by using the plan image and the current target radiotherapy plan execution control point data, and more specifically, the condition that the radiation is radiated to the plan image is simulated by using the treatment head rotation angle, the multi-leaf grating shape, the tungsten gate shape, the treatment couch position, the radiation jump number and the radiation dose rate in the current target radiotherapy plan execution control point data as radiation simulation conditions, so as to obtain the current target dose distribution.
Exemplarily, the target dose distribution determining unit 1232 is specifically configured to: if the current target dose distribution is the accumulated dose distribution of the planned radiation corresponding to the current fusion time point, determining the current dose distribution of the planned radiation corresponding to the current fusion time point according to the treatment head rotation angle, the multi-leaf grating shape, the tungsten gate shape, the treatment couch position, the radiation jump number and the radiation dose rate in the execution control point data of the planned image and the current target radiotherapy plan; and determining a cumulative dose distribution as a current target dose distribution according to the current dose distribution and at least one historical dose distribution of planned radiation corresponding to at least one historical fusion time point before the current fusion time point.
Wherein the historical fusing time point is a fusing time point at which time points are arranged before the current fusing time point. The historical dose distribution is the dose distribution corresponding to the current dose distribution, the current dose distribution is the dose distribution corresponding to the current fusion time point, and the historical dose distribution is the dose distribution corresponding to the historical fusion time point. The cumulative dose distribution is the cumulative result of the dose distributions corresponding to the plurality of single time points.
Specifically, in the radiotherapy plan, for a fusion time point, there is corresponding radiotherapy plan execution control point data, and according to the radiotherapy plan execution control point data, the radiation dose intensity distribution (abbreviated as dose distribution) of the planned radiation in the patient body can be calculated in advance. That is, each fusion time point in the radiotherapy plan has its corresponding dose distribution of the planned radiation. For the current fusion time point, the target dose distribution determining unit 1232 calculates the current dose distribution according to the treatment head rotation angle, the multi-leaf grating shape, the tungsten gate shape, the treatment couch position, the radiation jump number of the linear accelerator, and the radiation dose rate in the current target radiotherapy plan execution control point data. Likewise, the target dose distribution determining unit 1232 is also a historical dose distribution calculated one by one through the above-described procedure. And then accumulating the current dose distribution and a plurality of historical dose distributions corresponding to a plurality of historical fusion time points respectively to obtain the cumulative dose distribution of the planned radiation corresponding to the current pre-fusion time point. Therefore, a relatively accurate predictive treatment result of the radiotherapy plan can be obtained, and the accuracy of radiotherapy plan display can be further improved.
According to the technical scheme of the embodiment, a first fusion time point query unit is arranged in a target image determining module to query whether a current fusion time point exists in first time distribution; when the current fusion time point exists in the first time distribution, the first image acquisition unit acquires an image corresponding to the current fusion time point in the original image sequence as a current target image; and when the current fusion time point does not exist in the first time distribution, the second image acquisition unit interpolates and acquires the current target image according to the current fusion time point and the original image sequence. The method can obtain more accurate current target images and improve the accuracy of the current target images in the radiotherapy plan display process. Determining the data of the control point executed by the current target radiotherapy plan corresponding to the current fusion time point by setting a target control point data determining unit in a target dose distribution determining module according to the data of the control point executed by the original radiotherapy plan; the target dose distribution determining unit determines the current target dose distribution according to the control point data and the plan image executed by the target radiotherapy plan. More accurate current target dose distribution can be obtained, and therefore the accuracy of the display of the phased radiotherapy plan is further improved.
The following is an embodiment of a storage medium provided by an embodiment of the present invention, and the method operations performed by the storage medium belong to the same inventive concept as the operations performed by the radiotherapy plan display system in the above embodiments, and reference may be made to the embodiment of the radiotherapy plan display system in the embodiments of the storage medium for details that are not described in detail.
EXAMPLE III
The present embodiments provide a storage medium containing computer executable instructions which, when executed by a computer processor, are operable to perform a radiotherapy plan display method, the method comprising:
acquiring an original image sequence distributed at a first time and original radiotherapy plan execution control point data distributed at a second time, wherein the original image sequence and the original radiotherapy plan execution control point data correspond to the same object;
executing control point data according to the original image sequence and the original radiotherapy plan, determining a target image sequence and a target dose distribution sequence, and fusing the target image sequence and the target dose distribution sequence to obtain a plan display image sequence;
the display plans to display the image sequence.
Optionally, executing the control point data according to the original image sequence and the original radiotherapy plan, determining a target image sequence and a target dose distribution sequence, and fusing the target image sequence and the target dose distribution sequence to obtain a plan display image sequence includes:
determining a current fusion time point;
determining a current target image corresponding to the current fusion time point according to the original image sequence;
executing control point data according to an original radiotherapy plan, and determining current target dose distribution corresponding to a current fusion time point;
fusing the current target image and the current target dose distribution to obtain a current plan display image corresponding to the current fusion time point;
and updating the next fusion time point to the current fusion time point, and returning to execute the step of determining the current target image corresponding to the current fusion time point according to the original image sequence until the current fusion time point is the last fusion time point.
Optionally, determining, according to the original image sequence, a current target image corresponding to the current fusion time point includes:
inquiring whether a current fusion time point exists in the first time distribution;
if so, acquiring an image corresponding to the current fusion time point in the original image sequence as a current target image;
if not, interpolating to obtain the current target image according to the current fusion time point and the original image sequence.
Further, the obtaining of the current target image by interpolation according to the current fusion time point and the original image sequence includes:
respectively acquiring a first image corresponding to a first time point before the current fusion time point and a second image corresponding to a second time point after the current fusion time point from the original image sequence;
determining an image characteristic change trend according to the first image and the second image;
and taking the image characteristic change trend as an image interpolation constraint, and interpolating the first image and the second image according to the first time point, the current fusion time point and the second time point to obtain the current target image.
Optionally, executing the control point data according to the original radiotherapy plan, and determining the current target dose distribution corresponding to the current fusion time point includes:
determining the data of the control point of the execution of the current target radiotherapy plan corresponding to the current fusion time point according to the data of the control point of the execution of the original radiotherapy plan;
and executing the control point data and the plan image according to the target radiotherapy plan, and determining the current target dose distribution.
Wherein, according to the original radiotherapy plan execution control point data, determining the current target radiotherapy plan execution control point data corresponding to the current fusion time point comprises:
inquiring whether a current fusion time point exists in the second time distribution;
if so, acquiring radiotherapy plan execution control point data corresponding to the current fusion time point in the original radiotherapy plan execution control point data as current target radiotherapy plan execution control point data;
if not, the data of the control point executed by the current target radiotherapy plan is obtained through interpolation according to the current fusion time point and the data of the control point executed by the original radiotherapy plan.
Further, the step of obtaining the data of the control point executed by the current target radiotherapy plan through interpolation according to the data of the control point executed by the current fusion time point and the original radiotherapy plan comprises the following steps:
respectively acquiring first radiotherapy plan execution control point data corresponding to a third time point before the current fusion time point and second radiotherapy plan execution control point data corresponding to a fourth time point after the current fusion time point from the original radiotherapy plan execution control point data;
and interpolating the data of the first radiotherapy plan execution control point and the data of the second radiotherapy plan execution control point according to the third time point, the current fusion time point and the fourth time point to obtain data of the current target radiotherapy plan execution control point.
Optionally, executing the control point data and the planning image according to the target radiotherapy plan, and determining the current target dose distribution includes:
and when the planning image is a four-dimensional planning image, determining the current target dose distribution according to the control point data executed by the current target radiotherapy plan and the planning image corresponding to the current fusion time point in the four-dimensional planning image.
Optionally, executing the control point data and the planning image according to the target radiotherapy plan, and determining the current target dose distribution includes:
and determining the current target dose distribution according to the treatment head rotation angle, the multi-leaf grating shape, the tungsten gate shape, the treatment bed position, the radiation jump number and the radiation dose rate in the plan image and the execution control point data of the current target radiotherapy plan.
Optionally, when the current target dose distribution is an accumulated dose distribution of the planned radiation corresponding to the current fusion time point, executing the control point data and the planned image according to the target radiotherapy plan, and determining the current target dose distribution includes:
determining the current dose distribution of the planned radiation corresponding to the current fusion time point according to the treatment head rotation angle, the multi-leaf grating shape, the tungsten gate shape, the treatment couch position, the radiation jump number and the radiation dose rate in the execution control point data of the planned image and the current target radiotherapy plan;
and determining a cumulative dose distribution as a current target dose distribution according to the current dose distribution and at least one historical dose distribution of planned radiation corresponding to at least one historical fusion time point before the current fusion time point.
Computer storage media for embodiments of the invention may employ any combination of one or more computer-readable media. The computer readable medium may be a computer readable signal medium or a computer readable storage medium. A computer readable storage medium may be, for example, but not limited to, an electronic, magnetic, optical, electromagnetic, infrared, or semiconductor system, apparatus, or device, or any combination of the foregoing. More specific examples (a non-exhaustive list) of the computer readable storage medium would include the following: an electrical connection having one or more wires, a portable computer diskette, a hard disk, a Random Access Memory (RAM), a read-only memory (ROM), an erasable programmable read-only memory (EPROM or flash memory), an optical fiber, a portable compact disc read-only memory (CD-ROM), an optical storage device, a magnetic storage device, or any suitable combination of the foregoing. In the context of this document, a computer readable storage medium may be any tangible medium that can contain, or store a program for use by or in connection with an instruction execution system, apparatus, or device.
A computer readable signal medium may include a propagated data signal with computer readable program code embodied therein, for example, in baseband or as part of a carrier wave. Such a propagated data signal may take many forms, including, but not limited to, electro-magnetic, optical, or any suitable combination thereof. A computer readable signal medium may also be any computer readable medium that is not a computer readable storage medium and that can communicate, propagate, or transport a program for use by or in connection with an instruction execution system, apparatus, or device.
Program code embodied on a computer readable medium may be transmitted using any appropriate medium, including but not limited to wireless, wireline, optical fiber cable, RF, etc., or any suitable combination of the foregoing.
Computer program code for carrying out operations for aspects of the present invention may be written in any combination of one or more programming languages, including an object oriented programming language such as Java, Smalltalk, C + + or the like and conventional procedural programming languages, such as the "C" programming language or similar programming languages. The program code may execute entirely on the user's computer, partly on the user's computer, as a stand-alone software package, partly on the user's computer and partly on a remote computer or entirely on the remote computer or server. In the case of a remote computer, the remote computer may be connected to the user's computer through any type of network, including a Local Area Network (LAN) or a Wide Area Network (WAN), or the connection may be made to an external computer (for example, through the Internet using an Internet service provider).
It is to be noted that the foregoing is only illustrative of the preferred embodiments of the present invention and the technical principles employed. It will be understood by those skilled in the art that the present invention is not limited to the particular embodiments described herein, but is capable of various obvious changes, rearrangements and substitutions as will now become apparent to those skilled in the art without departing from the scope of the invention. Therefore, although the present invention has been described in greater detail by the above embodiments, the present invention is not limited to the above embodiments, and may include other equivalent embodiments without departing from the spirit of the present invention, and the scope of the present invention is determined by the scope of the appended claims.
Claims (11)
1. A radiotherapy plan display system, comprising:
the data acquisition device is used for acquiring an original image sequence distributed at a first time and original radiotherapy plan execution control point data distributed at a second time, wherein the original image sequence and the original radiotherapy plan execution control point data correspond to the same object;
the fusion device is used for determining a target image sequence according to the original image sequence, determining a target dose distribution sequence according to the original radiotherapy plan execution control point data, and fusing the target image sequence and the target dose distribution sequence to obtain a plan display image sequence, wherein the fusion device comprises a target image determination module, a target dose distribution determination module and a fusion module;
and the display device is used for displaying the planned display image sequence.
2. The system of claim 1, wherein the fusion device further comprises: a fusion time point determination module and a loop module, wherein,
the fusion time point determining module is used for determining the current fusion time point;
the target image determining module is used for determining a current target image corresponding to the current fusion time point according to the original image sequence;
the target dose distribution determining module is used for executing control point data according to the original radiotherapy plan and determining the current target dose distribution corresponding to the current fusion time point;
the fusion module is used for fusing the current target image and the current target dose distribution to obtain a current plan display image corresponding to the current fusion time point;
and the circulation module is used for updating the next fusion time point to the current fusion time point after the current plan display image is obtained, and triggering the execution of the target image determining module and the target dose distribution determining module until the current fusion time point is the last fusion time point.
3. The system of claim 2, wherein the target image determination module comprises:
a first time point query unit, configured to query whether the current fusion time point exists in the first time distribution;
a first image obtaining unit, configured to obtain, when the current fusion time point exists in the first time distribution, an image corresponding to the current fusion time point in the original image sequence as the current target image;
and a second image obtaining unit, configured to, when the current fusion time point does not exist in the first time distribution, interpolate to obtain the current target image according to the current fusion time point and the original image sequence.
4. The system of claim 3, wherein the second image acquisition unit is specifically configured to:
respectively acquiring a first image corresponding to a first time point before the current fusion time point and a second image corresponding to a second time point after the current fusion time point from the original image sequence;
determining an image characteristic change trend according to the first image and the second image;
and taking the image characteristic change trend as an image interpolation constraint, and interpolating the first image and the second image according to the first time point, the current fusion time point and the second time point to obtain the current target image.
5. The system of claim 2, wherein the target dose distribution determination module comprises:
the target control point data determining unit is used for determining the data of the current target radiotherapy plan execution control point corresponding to the current fusion time point according to the data of the original radiotherapy plan execution control point;
and the target dose distribution determining unit is used for executing the control point data and the plan image according to the current target radiotherapy plan and determining the current target dose distribution.
6. The system according to claim 5, wherein the target control point data determining unit comprises:
a second time point query subunit, configured to query whether the current fusion time point exists in the second time distribution;
a first control point data obtaining subunit, configured to, when the current fusion time point exists in the second time distribution, obtain radiotherapy plan execution control point data corresponding to the current fusion time point in the original radiotherapy plan execution control point data, as the current target radiotherapy plan execution control point data;
and a second control point data obtaining subunit, configured to, when the current fusion time point does not exist in the second time distribution, perform control point data according to the current fusion time point and the original radiotherapy plan, and perform interpolation to obtain the control point data for executing the current target radiotherapy plan.
7. The system according to claim 6, wherein the second control point data obtaining subunit is specifically configured to:
respectively acquiring first radiotherapy plan execution control point data corresponding to a third time point before the current fusion time point and second radiotherapy plan execution control point data corresponding to a fourth time point after the current fusion time point from the original radiotherapy plan execution control point data;
and interpolating the first radiotherapy plan execution control point data and the second radiotherapy plan execution control point data according to the third time point, the current fusion time point and the fourth time point to obtain the current target radiotherapy plan execution control point data.
8. The system according to claim 5, wherein the target dose distribution determining unit is specifically configured to:
and when the planning image is a four-dimensional planning image, determining the current target dose distribution according to the data of the current target radiotherapy plan execution control point and the planning image corresponding to the current fusion time point in the four-dimensional planning image.
9. The system according to claim 5 or 8, wherein the target dose distribution determining unit is specifically configured to:
and determining the current target dose distribution according to the treatment head rotation angle, the multi-leaf grating shape, the tungsten gate shape, the treatment couch position, the radiation jump number and the radiation dose rate in the plan image and the current target radiotherapy plan execution control point data.
10. The system according to claim 9, wherein the target dose distribution determining unit is specifically configured to:
if the current target dose distribution is the accumulated dose distribution of the planned radiation corresponding to the current fusion time point, determining the current dose distribution of the planned radiation corresponding to the current fusion time point according to the treatment head rotation angle, the multi-leaf grating shape, the tungsten gate shape, the treatment couch position, the radiation jump number and the radiation dose rate in the execution control point data of the planned image and the current target radiotherapy plan;
and determining the cumulative dose distribution as the current target dose distribution according to the current dose distribution and at least one historical dose distribution of planned radiation corresponding to at least one historical fusion time point before the current fusion time point.
11. A storage medium containing computer-executable instructions, which when executed by a computer processor, are configured to perform operations comprising:
acquiring an original image sequence distributed at a first time and original radiotherapy plan execution control point data distributed at a second time, wherein the original image sequence and the original radiotherapy plan execution control point data correspond to the same object;
determining a target image sequence according to the original image sequence, determining a target dose distribution sequence according to the original radiotherapy plan execution control point data, and fusing the target image sequence and the target dose distribution sequence to obtain a plan display image sequence;
and displaying the planned display image sequence.
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