CN104622505A - Ultrasonic detecting system and method for intracranial blood flow - Google Patents
Ultrasonic detecting system and method for intracranial blood flow Download PDFInfo
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Abstract
The invention provides an ultrasonic detecting system for intracranial blood flow. The system comprises a probe, a transmitting and receiving control module, a time gain wavelength amplifier, a wave velocity synthesis module and a signal processing module, wherein the probe comprises a plurality of ultrasonic transducer array elements, and the size of the probe is in accordance with the size of a skull; the transmitting and receiving control module controls the ultrasonic transducer array elements of the probe to transmit ultrasonic pulses into the patient skull, receive ultrasonic echo waves generated by the ultrasonic pulses, and transform the ultrasonic echo waves into electrical signals; the time gain wavelength amplifier is used for amplifying the electrical signals generated by the ultrasonic transducer array elements; the wave velocity synthesis module is used for processing the electrical signals which are amplified by the time gain wavelength amplifier and forming synthesized signals; the signal processing module is used for processing the synthesized signals generated by the wave velocity synthesis module and generating processing results. The invention further provides an ultrasonic detecting method for the intracranial blood flow, and the method enables an operator to easily capture Doppler frequency spectrum and enables intracranial blood flow detecting to be more straightforward.
Description
Technical field
The present invention relates to blood flow detection field, be specifically related to a kind of ultrasonic intracranial blood flow detection system and method.
Background technology
To analysis, intracranial vessel inspection judges that the health of people has vital effect, but the entrant sound of skull directly affects detection successful.Especially, intracranial vessel inspection is generally by probe being placed on Nie's window or neck occipital bone macropore place, makes acoustic beam pass Nie's window or Foramen magnum to detect intracranial vessel.
As non-invasive, economical, simple and easy to do, reproducible inspection method, transcranial doppler blood flow analysis instrument TCD is widely used clinical, has the advantage that Real-time and Dynamic evaluates blood stream rheology.But Transcranial Doppler analyzer generally selects single array element probe to carry out the imaging of Doppler's spectrogram, accurately can not locate intracranial vessel.Meanwhile, move towards information owing to cannot obtain blood vessel, the angle between supersonic speed and blood vessel move towards cannot be determined, causes corresponding Doppler measurement speed to there is certain error.
DCFI CDFI can well overcome the above problems, it completes Detection and diagnosis to blood vessel by DCFI technology, it both can observe hemodynamic change that is narrow or occlusive disease generation, can observe again pathological changes causes Endovascular blood flow full abnormal, and cerebral tissue architectural feature.
But current CDFI pops one's head in stock size comparatively greatly, and detecting head surface well can not agree with skull, thus affects imaging effect.In addition, the penetrance of CDFI probe is lower than TCD probe, thus affects the accuracy of intracranial vessel detection.
Being not difficult to find out, also there is certain defect in prior art.
Summary of the invention
The invention provides a kind of ultrasonic intracranial blood flow detection system and method, not only can improve the effect of DCFI, the accuracy that intracranial vessel detects can also be improved.
For achieving the above object, the invention provides a kind of ultrasonic intracranial blood flow detection system, comprising:
Probe, described probe comprises multiple ultrasonic transducer array element, and size and the skull of described probe agree with;
Launch and accept control module, described launch and accept control module controls described multiple ultrasonic transducer array elements of described probe and launches ultrasonic pulse to intracranial, receive ultrasonic echo that described ultrasonic pulse produces and convert described ultrasonic echo to the signal of telecommunication;
Time gain wavelength amplifier, amplifies for the signal of telecommunication generated described multiple ultrasonic transducer array element;
Velocity of wave synthesis module, for processing the signal of telecommunication after amplifying through described time gain wavelength amplifier, and forms composite signal;
Signal processing module, processes for the composite signal generated described velocity of wave synthesis module, and generating process result;
Display module, for showing the result that described signal processing module generates.
Present invention also offers a kind of method adopting described ultrasonic intracranial blood flow detection system to carry out ultrasonic intracranial blood flow detection, comprising:
Launch ultrasonic pulse;
Receive the ultrasonic echo that described ultrasonic pulse is given birth to, and convert described ultrasonic echo to the signal of telecommunication;
The described signal of telecommunication is amplified;
The signal of telecommunication after amplifying is processed, forms composite signal;
Described composite signal is processed, and generating process result;
Generated result is shown.
The present invention proposes a kind of ultrasonic intracranial blood vessel detection system and method, by adopting a kind of undersized low frequency phased array probe, can solve the problem that DCFI probe agrees with skull, improve the penetrance of DCFI and spectral imaging, and then improve imaging effect.First the present invention processes ultrasound echo signal, forms composite signal, then carries out multi task process to composite signal, improve the accuracy of spectrum measurement, make operator more easily catch Doppler frequency spectrum, make the blood flow detection of intracranial more simple and clear.
Accompanying drawing explanation
Fig. 1 is the structured flowchart of the embodiment of a kind of ultrasonic intracranial blood flow detection system provided by the invention;
Fig. 2 is the structured flowchart of B signal processing submodule in Fig. 1;
Fig. 3 is the structured flowchart of Color signal processing submodule in Fig. 1;
Fig. 4 is the structured flowchart of PW signal processing submodule in Fig. 1;
Fig. 5 is the flow chart of the embodiment of a kind of ultrasonic intracranial blood flow detection method provided by the invention;
Fig. 6 is the first processing mode flow chart of composite signal in the embodiment of a kind of ultrasonic intracranial blood flow detection method provided by the invention;
Fig. 7 is the second processing mode flow chart of composite signal in the embodiment of a kind of ultrasonic intracranial blood flow detection method provided by the invention;
Fig. 8 is the third processing mode flow chart of composite signal in the embodiment of a kind of ultrasonic intracranial blood flow detection method provided by the invention.
Detailed description of the invention
For making the object of the embodiment of the present invention, technical scheme and advantage clearly, below in conjunction with the embodiment of the present invention, the technical scheme in the embodiment of the present invention is clearly and completely described.It should be noted that, in accompanying drawing or description, similar or identical element uses identical Reference numeral.
The embodiment of the present invention proposes a kind of ultrasonic intracranial blood flow detection system and method, by adopting a kind of undersized low frequency phased array probe, can solve the problem that DCFI probe agrees with skull, improve the penetrance of DCFI and spectral imaging, and then improve imaging effect.First the present invention processes ultrasound echo signal, forms composite signal, then carries out multi task process to composite signal, improve the accuracy of spectrum measurement, make operator more easily catch Doppler frequency spectrum, make the blood flow detection of intracranial more simple and clear.
Below ultrasonic intracranial blood flow detection system is described further:
A kind of ultrasonic intracranial blood flow detection system, as shown in Figure 1, comprising:
Probe, this probe comprises multiple ultrasonic transducer array element, these ultrasonic transducer array elements can be launched ultrasonic pulse (ultrasound wave) to scanning target (such as, patient's intracranial) and receive the ultrasonic echo of scanning target reflection, and convert ultrasonic echo to the signal of telecommunication.
In embodiments of the invention, size and the skull of this probe agree with.Here, the size of said probe and skull " agree with " refer to probe size and skull on the size in various holes adapt thus the ultrasound wave that the ultrasonic transducer array element of popping one's head in is launched can to spread into skull inner and can not be stopped by skull.
Such as, in an embodiment, the size of probe can be agreed with the Foramen magnum of skull or Nie's window, and the size of the size of namely popping one's head in and the Foramen magnum of skull or Nie's window adapts thus the ultrasound wave that the ultrasonic transducer array element of popping one's head in is launched can rush across Foramen magnum or Nie's window spreads into skull inside and can not be stopped by skull.Easy understand, in embodiments of the invention, the size of probe also can be agree with any other the size being suitable for allowing ultrasound wave spread into the hole of intracranial by it of skull.
It should be noted that, the present embodiment preferred probes is low frequency phased array probe, and relative to conventional art, the present embodiment devises a less mid frequency of size phased array probe on the low side, the Breadth Maximum of popping one's head in the present embodiment is 12mm, and its mid frequency is lower than 2.5MHz.Small size can more easily and Foramen magnum or Nie's window agree with, thus obtain better detection perform.This probe global shape can be rectangle or polygon or ellipse.
Launch and accept control module (also referred to as transmitting/receiving control module), this launch and accept control module controls multiple ultrasonic transducer array elements of probe and launches ultrasonic pulse to intracranial, receive ultrasonic echo (namely by the tissue of intracranial or organic reflex or back scattered ultrasonic echo) that ultrasonic pulse produces and convert these ultrasonic echos to the signal of telecommunication.Running parameter and the working condition such as the ultrasonic transducer array element that the shape of ultrasonic pulse that this launch and accept control module controls to launch, time delay and participating in is launched.
Time gain wavelength amplifier, amplifies for the signal of telecommunication generated described ultrasonic transducer.It should be noted that, the described signal of telecommunication amplifies through described time gain wavelength amplifier, to compensate the ultrasonic attenuation under different depth.
Velocity of wave synthesis module, for processing the signal of telecommunication after amplifying through described time gain wavelength amplifier, and forms composite signal.It should be noted that, described velocity of wave synthesis module the concrete effect that plays be: adjust the time delay of each array element ultrasonic echo and apodization carried out to it, to improve the signal to noise ratio of current reception ultrasound echo signal.
Signal processing module, processes for the composite signal generated described velocity of wave synthesis module, and generating process result.
Display module, for showing the result that described signal processing module generates.
As preferably, described signal processing module comprises: B signal processing submodule, for processing described composite signal, and generates black white image data; Color(is colored) signal processing submodule, for processing described composite signal, and generate color blood-stream image data; PW signal processing submodule, for processing described composite signal, and generates doppler spectrum data.
It should be noted that, as preferably, as shown in Figure 2, described B signal processing submodule comprises:
Quadrature demodulation unit, for being decomposed by described composite signal, and generates decomposition result; Detection unit, processes for the decomposition result generated described quadrature demodulation unit, and obtains image envelope information; Image envelope processing unit, for carrying out logarithmic compression and image procossing to described image envelope information, and generates black white image data.
As preferably, as shown in Figure 3, described Color signal processing submodule comprises:
Quadrature demodulation unit, for being decomposed by described composite signal, and generates decomposition result; Wall filtering unit, carries out wall filtering process for the decomposition result generated by described quadrature demodulation unit, the strong organization ultrasonic echo-signal namely in decomposition result described in filtering, and generating process result; Blood flow parameter acquiring unit, obtains blood flow parameter for the result generated according to wall filtering unit, and as preferably, described blood flow parameter includes but not limited to blood flow rate, variance and energy; Blood flow post-processing unit, for processing described blood flow parameter, the present embodiment preferably adopts and carries out the relevant and smooth operation of frame etc. to improve blood flow form to described blood flow parameter, and generates color blood-stream image data.
As preferably, as shown in Figure 4, described PW signal processing submodule comprises:
Quadrature demodulation unit, for being decomposed by described composite signal, and generates decomposition result.
Range gating unit, carries out range gating for the decomposition result generated by described quadrature demodulation unit, and generates range gating result.It should be noted that, I, Q two-way component after described quadrature demodulation unit decomposition needs respectively through range gating, and namely cumulative within the specific time period, this accumulation interval section and pulse Doppler transmitted pulse are all selected according to practical situation by operator.
Wall filtering unit, carries out wall filtering process for the range gating result generated by described range gating unit, and generating process result; It should be noted that, described wall filtering unit is that employing high pass filter carries out wall filtering process to described range gating result, and it can the clutter that caused by static or microinching tissue of filtering.
Power spectrum acquiring unit, for obtaining the power spectrum of the result that described wall filtering unit generates; It should be noted that, I, Q two-way component after described wall filtering cell processing, consists predominantly of the kinetic echo of erythrocyte, is sent to power spectrum acquiring unit, as preferably, described power spectrum acquiring unit generally adopts fast fourier transform to carry out rated output spectrum.
Spectrum compression unit, the power spectrum for obtaining described power spectrum acquiring unit carries out compression process, and generates doppler spectrum data.It should be noted that, because the power spectrum dynamic range calculated is too large, the power spectrum at every turn calculated needs through overcompression process, to be compressed to gray scale indication range.What the last Doppler frequency spectrum figure shown on display module represented is certain moment, certain speed, i.e. the power spectral intensity of certain frequency shift (FS).
As preferably, described PW signal processing submodule comprises further:
Spectrum envelope detecting unit, analyzes for the result generated described spectrum compression unit, and generates doppler spectrum data.As preferably, the data analysis after the doppler spectrum data that described spectrum envelope detecting unit generates described spectrum compression unit, with from motion tracking peak velocity and average speed over time, and shows in real time on Doppler frequency spectrum figure.
As preferably, described PW signal processing submodule comprises further:
Sound processing unit, processes for the result generated by described wall filtering processing unit, and obtains voice data; D/A module, for carrying out conversion process to described voice data, and obtains conversion process result; Speaker, for receiving and playing the conversion process result of described D/A unit.Described I, Q two paths of data after wall filtering can also be sent to acoustic processing module, to form positive blood flow and inverse blood flow two-way voice data, and after D/A module converts, is sent to speaker respectively, produces forward and inverse blood flow sound.
As preferably, the present embodiment additionally provides a kind of method adopting described ultrasonic intracranial blood flow detection system to carry out ultrasonic intracranial blood flow detection, and as shown in Figure 5, it comprises:
Launch ultrasonic pulse; It should be noted that, generation ultrasonic pulse herein, also comprise the shape of control ultrasonic pulse, time delay and participate in the array element of transmitting.
Receive the ultrasonic echo that described ultrasonic pulse is given birth to, and convert described ultrasonic echo to the signal of telecommunication.
The described signal of telecommunication is amplified; The object that the described signal of telecommunication amplifies is: compensate the ultrasonic attenuation under different depth.
The signal of telecommunication after amplifying is processed, forms composite signal; Namely adjust the time delay of each array element ultrasonic echo and apodization is carried out to it, to improve the signal to noise ratio of current reception ultrasound echo signal.
Described composite signal is processed, and generating process result.
Generated result is shown.
As preferably, to " described composite signal processes, and generating process result ", specifically described composite signal is carried out three kinds of process:
As shown in Figure 6, the first processing mode is:
Described composite signal is decomposed, and generates decomposition result; Described decomposition result is processed, and obtains image envelope information; Logarithmic compression and image procossing are carried out to described image envelope information, and generates black white image data.
As shown in Figure 7, the second processing mode is:
Described composite signal is decomposed, and generates decomposition result.Described decomposition result is carried out wall filtering process, and generating process result; Namely the strong organization ultrasonic echo-signal in decomposition result described in filtering.According to the result generated to obtain blood flow parameter; As preferably, described blood flow parameter includes but not limited to blood flow rate, variance and energy.Process described blood flow parameter, the present embodiment preferably adopts and carries out the relevant and smooth operation of frame etc. to improve blood flow form to described blood flow parameter, and generates color blood-stream image data.
As shown in Figure 8, the third processing mode is:
Described composite signal is decomposed, and generates decomposition result.Generated decomposition result is carried out range gating, and generates range gating result; I, Q two-way component after decomposing needs respectively through range gating, and namely cumulative within the specific time period, this accumulation interval section and pulse Doppler transmitted pulse are all selected according to practical situation by operator.Described range gating result is carried out wall filtering process, and generating process result; The present embodiment preferably adopts a high pass filter to carry out wall filtering process to described range gating result, and it can the clutter that caused by static or microinching tissue of filtering.The power spectrum of the result generated after obtaining described wall filtering process; As preferably, fast fourier transform is generally adopted to carry out rated output spectrum.Compression process is carried out to obtained power spectrum, and generates doppler spectrum data; Because the power spectrum dynamic range calculated is too large, the power spectrum at every turn calculated needs through overcompression process, to be compressed to gray scale indication range.What the Doppler frequency spectrum figure finally shown represented is certain moment, certain speed, i.e. the power spectral intensity of certain frequency shift (FS).
As preferably, the third processing mode described also comprises:
The result generated after result compression process is analyzed, and generates doppler spectrum data; In order to from motion tracking peak velocity and average speed over time, and show in real time on Doppler frequency spectrum figure.
As preferably, the third processing mode described also comprises:
The result generated after wall filtering process is processed, and obtains voice data; Described voice data carries out conversion process, and obtains conversion process result; Speaker is used to receive and play the conversion process result of described D/A unit.Described I, Q two paths of data after wall filtering can also be sent to acoustic processing module, to form positive blood flow and inverse blood flow two-way voice data, and after D/A module converts, is sent to speaker respectively, produces forward and inverse blood flow sound.
The embodiment of the present invention proposes a kind of ultrasonic intracranial blood flow detection system and method, by adopting a kind of undersized low frequency phased array probe, can solve the problem that DCFI probe agrees with skull, improve the penetrance of DCFI and spectral imaging, and then improve imaging effect.First the present invention processes ultrasound echo signal, form composite signal, then composite signal is carried out to the multi task process of B signal, Color signal and PW signal, improve the accuracy of spectrum measurement, make operator more easily catch Doppler frequency spectrum, make the blood flow detection of intracranial more simple and clear.
Last it is noted that above embodiment is only in order to illustrate technical scheme of the present invention, be not intended to limit; Although with reference to previous embodiment to invention has been detailed description, those of ordinary skill in the art is to be understood that: it still can be modified to the technical scheme described in previous embodiment, or carries out equivalent replacement to wherein portion of techniques feature; And these amendments or replacement, do not make the essence of appropriate technical solution depart from the spirit and scope of various embodiments of the present invention technical scheme.
Claims (11)
1. a ultrasonic intracranial blood flow detection system, is characterized in that, comprising:
Probe, described probe comprises multiple ultrasonic transducer array element, and size and the skull of described probe agree with;
Launch and accept control module, described launch and accept control module controls described multiple ultrasonic transducer array elements of described probe and launches ultrasonic pulse to intracranial, receive ultrasonic echo that described ultrasonic pulse produces and convert described ultrasonic echo to the signal of telecommunication;
Time gain wavelength amplifier, amplifies for the signal of telecommunication generated described multiple ultrasonic transducer array element;
Velocity of wave synthesis module, for processing the signal of telecommunication after amplifying through described time gain wavelength amplifier, and forms composite signal;
Signal processing module, processes for the composite signal generated described velocity of wave synthesis module, and generating process result;
Display module, for showing the result that described signal processing module generates.
2. ultrasonic intracranial blood flow detection system according to claim 1, is characterized in that, described probe is low frequency phased array probe.
3. ultrasonic intracranial blood flow detection system according to claim 2, is characterized in that, the Breadth Maximum of described probe is 12mm, and its mid frequency is lower than 2.5MHz.
4. ultrasonic intracranial blood flow detection system according to claim 1, it is characterized in that, described signal processing module comprises:
B signal processing submodule, for processing described composite signal, and generates black white image data;
Color signal processing submodule, for processing described composite signal, and generates color blood-stream image data;
PW signal processing submodule, for processing described composite signal, and generates doppler spectrum data.
5. ultrasonic intracranial blood flow detection system according to claim 4, is characterized in that, described B signal processing submodule comprises:
Quadrature demodulation unit, for being decomposed by described composite signal, and generates decomposition result;
Detection unit, processes for the decomposition result generated described quadrature demodulation unit, and obtains image envelope information;
Image envelope processing unit, for carrying out logarithmic compression and image procossing to described image envelope information, and generates black white image data.
6. ultrasonic intracranial blood flow detection system according to claim 4, is characterized in that, described Color signal processing submodule comprises:
Quadrature demodulation unit, for being decomposed by described composite signal, and generates decomposition result;
Wall filtering unit, carries out wall filtering process for the decomposition result generated by described quadrature demodulation unit, and generating process result;
Blood flow parameter acquiring unit, obtains blood flow parameter for the result generated according to wall filtering unit;
Blood flow post-processing unit, for processing described blood flow parameter, and generates color blood-stream image data.
7. ultrasonic intracranial blood flow detection system according to claim 4, is characterized in that, described PW signal processing submodule comprises:
Quadrature demodulation unit, for being decomposed by described composite signal, and generates decomposition result;
Range gating unit, carries out range gating for the decomposition result generated by described quadrature demodulation unit, and generates range gating result;
Wall filtering unit, carries out wall filtering process for the range gating result generated by described range gating unit, and generating process result;
Power spectrum acquiring unit, for obtaining the power spectrum of the result that described wall filtering unit generates;
Spectrum compression unit, the power spectrum for obtaining described power spectrum acquiring unit carries out compression process, and generates doppler spectrum data.
8. ultrasonic intracranial blood flow detection system according to claim 4, is characterized in that, described PW signal processing submodule comprises:
Quadrature demodulation unit, for being decomposed by described composite signal, and generates decomposition result;
Range gating unit, carries out range gating for the decomposition result generated by described quadrature demodulation unit, and generates range gating result;
Wall filtering unit, carries out wall filtering process for the range gating result generated by described range gating unit, and generating process result;
Power spectrum acquiring unit, for obtaining the power spectrum of the result that described wall filtering unit generates;
Spectrum compression unit, the power spectrum for obtaining described power spectrum acquiring unit carries out compression process, and generating process result;
Spectrum envelope detecting unit, analyzes for the result generated described spectrum compression unit, and generates doppler spectrum data.
9. ultrasonic intracranial blood flow detection system according to claim 4, is characterized in that, described PW signal processing submodule comprises:
Quadrature demodulation unit, for being decomposed by described composite signal, and generates decomposition result;
Range gating unit, carries out range gating for the decomposition result generated by described quadrature demodulation unit, and generates range gating result;
Wall filtering unit, carries out wall filtering process for the range gating result generated by described range gating unit, and generating process result;
Sound processing unit, processes for the result generated by described wall filtering processing unit, and obtains voice data;
D/A module, for carrying out conversion process to described voice data, and obtains conversion process result;
Speaker, for receiving and playing the conversion process result of described D/A unit.
10. ultrasonic intracranial blood flow detection system as claimed in any of claims 1 to 9, is characterized in that, the size of described probe and skull agree with and comprise: the size of described probe and the Foramen magnum of skull or Nie's window agree with.
11. 1 kinds of methods adopting ultrasonic intracranial blood flow detection system according to claim 1 to carry out ultrasonic intracranial blood flow detection, is characterized in that, comprising:
Launch ultrasonic pulse;
Receive the ultrasonic echo that described ultrasonic pulse is given birth to, and convert described ultrasonic echo to the signal of telecommunication;
The described signal of telecommunication is amplified;
The signal of telecommunication after amplifying is processed, forms composite signal;
Described composite signal is processed, and generating process result;
Generated result is shown.
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| CN116458925A (en) * | 2023-06-15 | 2023-07-21 | 山东百多安医疗器械股份有限公司 | Portable non-blind area multi-mode ultrasonic electrocardio system |
| CN116458925B (en) * | 2023-06-15 | 2023-09-01 | 山东百多安医疗器械股份有限公司 | Portable non-blind area multi-mode ultrasonic electrocardio system |
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