CN104606623A - Traditional Chinese medicine extract for alleviating hangover and preparation method of traditional Chinese medicine extract - Google Patents
Traditional Chinese medicine extract for alleviating hangover and preparation method of traditional Chinese medicine extract Download PDFInfo
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- CN104606623A CN104606623A CN201510061583.3A CN201510061583A CN104606623A CN 104606623 A CN104606623 A CN 104606623A CN 201510061583 A CN201510061583 A CN 201510061583A CN 104606623 A CN104606623 A CN 104606623A
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Abstract
The invention belongs to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine extract for alleviating hangover and a preparation method of the traditional Chinese medicine extract. The traditional Chinese medicine extract comprises 5-14 parts of 60wt% amomum tsao-ko ethanol-water extract, 3-9 parts of a white hyacinth bean ethyl acetate extract, 4-8 parts of a sophora flavescens water extract, 5-10 parts of 80wt% baeckea frutescens ethanol extract and 4-11 parts of a magnolia obavata ethanol extract. The preparation method comprises the following steps: extracting, separating and concentrating kinds of extracts, mixing the 60wt% amomum tsao-ko ethanol-water extract, the white hyacinth bean ethyl acetate extract, the sophora flavescens water extract, the 80wt% baeckea frutescens ethanol extract and the magnolia obavata ethanol extract in parts by weight; and mixing kinds of components evenly, so as to obtain the traditional Chinese medicine extract for alleviating the hangover.
Description
Technical field
The invention belongs to the field of Chinese medicines, relate to a kind of Chinese medicine extract and preparation method thereof, especially relate to a kind of Chinese medicine extract relieved the effect of alcohol and preparation method thereof.
Background technology
The Chinese medicine relieved the effect of alcohol comprises flower of Radix Puerariae, Radix Sophorae Flavescentis, Flos Chrysanthemi, Semen Lablab Album, Semen Myristicae, Fructus Tsaoko etc.Flower of Radix Puerariae is apt to alcoholic intoxication, and stomach function regulating of being amusing, quenches one's thirst, and cures mainly insobriety, headache and dizziness, and excessive thirst is vomitted, and chest and diaphragm is glutted.Semen Myristicae has warming middle-JIAO to promote flow of QI, intestine-stabling and anti-diarrheal, the merit helped digestion." Japan hanako materia medica " carries it, and " in tune, the therapeutic method to keep the adverse QI flowing downwards, antidiarrheal dysentery, appetizing, helps digestion.The outer network of skin, the therapeutic method to keep the adverse QI flowing downwards, alcoholic intoxication, controls cholera." " must join book on Chinese herbal medicine " think it " disappear dyspepsia, alcoholic intoxication." Flos Chrysanthemi energy dispelling wind and heat pathogens, suppressing the hyperactive liver improving eyesight, heat-clearing and toxic substances removing.The spleen invigorating of Semen Lablab Album energy, removing dampness, to relieve summer heat.Chinese medicinal alcoholism-relieving reason comprises protection the intestines and stomach, reduces the picked-up of ethanol; Diaphoresis diuresis, the discharge of accelerating alcohol; Act on the enzyme of alcohol metabolism, the degraded of accelerating alcohol; Hepatoprotective.The composition that specifically can relieve the effect of alcohol in the above-mentioned various Chinese medicine for relieving the effect of alcohol is also indefinite.Indefinite due to its concrete composition, therefore its effect of relieving the effect of alcohol need to improve.
Summary of the invention
The technical problem solved: Chinese medicine and the Western medicine with antialcoholism action are all more, the object of this invention is to provide a kind of novel Sobering-up Chinese medicine extract with good sober-up function and preparation method thereof.
Technical scheme: in order to improve the sober-up function of Chinese medicine, the invention discloses a kind of Chinese medicine extract relieved the effect of alcohol and preparation method thereof, and the described Chinese medicine extract relieved the effect of alcohol comprises following Chinese medicine extract by weight:
Fructus Tsaoko 60wt% ethanol-water extraction thing 5-14 part,
Semen Lablab Album ethyl acetate extract 3-9 part,
Radix Sophorae Flavescentis water extract 4-8 part,
Folium Baeckeae 80wt% ethanol extraction 5-10 part,
Cortex Magnoliae Officinalis ethanol extraction 4-11 part.
Described a kind of Chinese medicine extract relieved the effect of alcohol, comprises following Chinese medicine extract further:
Fructus Tsaoko 60wt% ethanol-water extraction thing 7-11 part,
Semen Lablab Album ethyl acetate extract 5-8 part,
Radix Sophorae Flavescentis water extract 5-7 part,
Folium Baeckeae 80wt% ethanol extraction 6-9 part,
Cortex Magnoliae Officinalis ethanol extraction 7-10 part.
Described a kind of Chinese medicine extract relieved the effect of alcohol, comprises following Chinese medicine extract further:
Fructus Tsaoko 60wt% ethanol-water extraction thing 9 parts,
Semen Lablab Album ethyl acetate extract 7 parts,
Radix Sophorae Flavescentis water extract 6 parts,
Folium Baeckeae 80wt% ethanol extraction 8 parts,
Cortex Magnoliae Officinalis ethanol extraction 8 parts.
A preparation method for the Chinese medicine extract relieved the effect of alcohol, step is as follows:
(1) get dry Fructus Tsaoko, carry out stirring extract after pulverizing with 60wt% ethanol water, centrifugal after extracting, getting the supernatant, is Fructus Tsaoko 60wt% ethanol-water extraction thing after concentrated;
(2) getting Semen Lablab Album, extract after pulverizing with ethyl acetate solution, filter, get filtrate after extracting, is Semen Lablab Album ethyl acetate extract after filtrate is concentrated;
(3) Radix Sophorae Flavescentis is pulverized, carry out stirring with pure water after pulverizing and extract, centrifugalize after extracting, after removing precipitation, supernatant concentration is obtained Radix Sophorae Flavescentis water extract;
(4) get dry Folium Baeckeae, by Folium Baeckeae mechanical activation comminution, the ethanol water pulverizing rear 80wt% extracts, centrifugal after extracting, and gets clear liquid and carries out vacuum concentration, and concentrate is the Folium Baeckeae 80wt% ethanol extraction of preparation;
(5) extracting carrying out stirring with ethanol after Cortex Magnoliae Officinalis pulverizing, leaving standstill after extracting, getting the Cortex Magnoliae Officinalis ethanol extract on upper strata, concentrating and obtain Cortex Magnoliae Officinalis ethanol extraction;
(6) Fructus Tsaoko 60wt% ethanol-water extraction thing 5-14 part, Semen Lablab Album ethyl acetate extract 3-9 part, Radix Sophorae Flavescentis water extract 4-8 part, Folium Baeckeae 80wt% ethanol extraction 5-10 part, Cortex Magnoliae Officinalis ethanol extraction 4-11 part is got by weight, above-mentioned each composition is mixed to evenly, for having the Chinese medicine extract of antialcoholism function.
The preparation method of described a kind of Chinese medicine extract relieved the effect of alcohol, when described Fructus Tsaoko extracts, Extracting temperature is 55 DEG C, and extraction time is 3h, and Fructus Tsaoko and 60wt% ethanol water weight ratio are 1:6.
The preparation method of described a kind of Chinese medicine extract relieved the effect of alcohol, when described Semen Lablab Album extracts, Extracting temperature is 50 DEG C, and extraction time is 5h, and Semen Lablab Album and ethyl acetate weight ratio are 1:10.
The preparation method of described a kind of Chinese medicine extract relieved the effect of alcohol, when described Folium Baeckeae extracts, Extracting temperature is 60 DEG C, and extraction time is 2h, and Folium Baeckeae and 80wt% ethanol weight ratio are 1:7.
The preparation method of described a kind of Chinese medicine extract relieved the effect of alcohol, when described Radix Sophorae Flavescentis extracts, Extracting temperature is room temperature, and extraction time is 6h, and Radix Sophorae Flavescentis and water weight ratio are 1:5.
The preparation method of described a kind of Chinese medicine extract relieved the effect of alcohol, when described Cortex Magnoliae Officinalis extracts, Extracting temperature is 40 DEG C, and extraction time is 6h, and Cortex Magnoliae Officinalis and ethanol weight ratio are 1:8.
Beneficial effect: the Chinese medicine extract with good antialcoholism action of the present invention is different from traditional Sobering-up Chinese medicine, the Chinese medicine with antialcoholism action is researched and developed targetedly, specify that the effect of the concrete composition in concrete Chinese medicine, also find the Chinese medicine ingredients in Folium Baeckeae and Cortex Magnoliae Officinalis with sober-up function in addition, further improve the antialcoholism action of Chinese medicine extract.
Detailed description of the invention
In following embodiment and comparative example, Fructus Tsaoko 60wt% ethanol-water extraction thing, Semen Lablab Album ethyl acetate extract, Radix Sophorae Flavescentis water extract, Folium Baeckeae 80wt% ethanol extraction, Cortex Magnoliae Officinalis ethanol extraction are following extraction process:
(1) dry Fructus Tsaoko is got, carry out stirring with 60wt% ethanol water after pulverizing to extract, when described Fructus Tsaoko extracts, Extracting temperature is 55 DEG C, extraction time is 3h, Fructus Tsaoko and 60wt% ethanol water weight ratio are 1:6, centrifugal after extracting, getting the supernatant, is Fructus Tsaoko 60wt% ethanol-water extraction thing after concentrated;
(2) get Semen Lablab Album, extract after pulverizing with ethyl acetate solution, when described Semen Lablab Album extracts, Extracting temperature is 50 DEG C, extraction time is 5h, and Semen Lablab Album and ethyl acetate weight ratio are 1:10, filters after extracting, getting filtrate, is Semen Lablab Album ethyl acetate extract after filtrate is concentrated;
(3) pulverized by Radix Sophorae Flavescentis, carry out stirring with pure water after pulverizing and extract, when described Radix Sophorae Flavescentis extracts, Extracting temperature is room temperature, and extraction time is 6h, and Radix Sophorae Flavescentis and water weight ratio are 1:5, and supernatant concentration, after removing precipitation, is obtained Radix Sophorae Flavescentis water extract by centrifugalize after extracting;
(4) dry Folium Baeckeae is got, by Folium Baeckeae mechanical activation comminution, the ethanol water pulverizing rear 80wt% extracts, when described Folium Baeckeae extracts, Extracting temperature is 60 DEG C, extraction time is 2h, and Folium Baeckeae and 80wt% ethanol weight ratio are 1:7, centrifugal after extracting, get clear liquid and carry out vacuum concentration, concentrate is the Folium Baeckeae 80wt% ethanol extraction of preparation;
(5) carry out stirring with ethanol after being pulverized by Cortex Magnoliae Officinalis to extract, when described Cortex Magnoliae Officinalis extracts, Extracting temperature is 40 DEG C, and extraction time is 6h, Cortex Magnoliae Officinalis and ethanol weight ratio are 1:8, leave standstill after extracting, get the Cortex Magnoliae Officinalis ethanol extract on upper strata, concentrate and obtain Cortex Magnoliae Officinalis ethanol extraction.
Embodiment 1
Get by weight Fructus Tsaoko 60wt% ethanol-water extraction thing 14 parts,
Semen Lablab Album ethyl acetate extract 9 parts,
Radix Sophorae Flavescentis water extract 4 parts,
Folium Baeckeae 80wt% ethanol extraction 10 parts,
Cortex Magnoliae Officinalis ethanol extraction 11 parts, is mixed to evenly by above-mentioned each composition, for having the Chinese medicine extract of antialcoholism function.
Embodiment 2
Get by weight Fructus Tsaoko 60wt% ethanol-water extraction thing 5 parts,
Semen Lablab Album ethyl acetate extract 3 parts,
Radix Sophorae Flavescentis water extract 8 parts,
Folium Baeckeae 80wt% ethanol extraction 5 parts,
Cortex Magnoliae Officinalis ethanol extraction 4 parts, is mixed to evenly by above-mentioned each composition, for having the Chinese medicine extract of antialcoholism function.
Embodiment 3
Get by weight Fructus Tsaoko 60wt% ethanol-water extraction thing 7 parts,
Semen Lablab Album ethyl acetate extract 8 parts,
Radix Sophorae Flavescentis water extract 7 parts,
Folium Baeckeae 80wt% ethanol extraction 6 parts,
Cortex Magnoliae Officinalis ethanol extraction 7 parts, is mixed to evenly by above-mentioned each composition, for having the Chinese medicine extract of antialcoholism function.
Embodiment 4
Get by weight Fructus Tsaoko 60wt% ethanol-water extraction thing 11 parts,
Semen Lablab Album ethyl acetate extract 5 parts,
Radix Sophorae Flavescentis water extract 5 parts,
Folium Baeckeae 80wt% ethanol extraction 9 parts,
Cortex Magnoliae Officinalis ethanol extraction 10 parts, is mixed to evenly by above-mentioned each composition, for having the Chinese medicine extract of antialcoholism function.
Embodiment 5
Get by weight Fructus Tsaoko 60wt% ethanol-water extraction thing 9 parts,
Semen Lablab Album ethyl acetate extract 7 parts,
Radix Sophorae Flavescentis water extract 6 parts,
Folium Baeckeae 80wt% ethanol extraction 8 parts,
Cortex Magnoliae Officinalis ethanol extraction 8 parts, is mixed to evenly by above-mentioned each composition, for having the Chinese medicine extract of antialcoholism function.
Comparative example
Get by weight Fructus Tsaoko 60wt% ethanol-water extraction thing 14 parts,
Semen Lablab Album ethyl acetate extract 9 parts,
Radix Sophorae Flavescentis water extract 4 parts, is mixed to evenly by above-mentioned each composition, for having the Chinese medicine extract of antialcoholism function.
Drunk crowd is after taking Sobering-up Chinese medicine extract of the present invention, obtain good relieving the effect of alcohol, recover normal condition, drunk crowd is totally 120 people, often organizes 20 people, and drunk situation relatively, Chinese medicine extract of the present invention is taken after drunk, take 3g respectively, after half an hour, relieve the effect of alcohol completely, significantly relieve the effect of alcohol and unchanged crowd's number as follows:
The above results can draw, after to Chinese medicine extract kind and ratio optimization, the Be very effective that embodiment 5 obtains due to other embodiments and comparative example, and do not add Folium Baeckeae 80wt% ethanol extraction, Cortex Magnoliae Officinalis ethanol extraction the effect of relieving the effect of alcohol of comparative example the poorest.
Claims (9)
1. the Chinese medicine extract relieved the effect of alcohol, is characterized in that the described Chinese medicine extract relieved the effect of alcohol comprises following Chinese medicine extract by weight:
Fructus Tsaoko 60wt% ethanol-water extraction thing 5-14 part,
Semen Lablab Album ethyl acetate extract 3-9 part,
Radix Sophorae Flavescentis water extract 4-8 part,
Folium Baeckeae 80wt% ethanol extraction 5-10 part,
Cortex Magnoliae Officinalis ethanol extraction 4-11 part.
2. a kind of Chinese medicine extract relieved the effect of alcohol according to claim 1, is characterized in that the described Chinese medicine extract relieved the effect of alcohol comprises following Chinese medicine extract by weight:
Fructus Tsaoko 60wt% ethanol-water extraction thing 7-11 part,
Semen Lablab Album ethyl acetate extract 5-8 part,
Radix Sophorae Flavescentis water extract 5-7 part,
Folium Baeckeae 80wt% ethanol extraction 6-9 part,
Cortex Magnoliae Officinalis ethanol extraction 7-10 part.
3. a kind of Chinese medicine extract relieved the effect of alcohol according to claim 1, is characterized in that the described Chinese medicine extract relieved the effect of alcohol comprises following Chinese medicine extract by weight:
Fructus Tsaoko 60wt% ethanol-water extraction thing 9 parts,
Semen Lablab Album ethyl acetate extract 7 parts,
Radix Sophorae Flavescentis water extract 6 parts,
Folium Baeckeae 80wt% ethanol extraction 8 parts,
Cortex Magnoliae Officinalis ethanol extraction 8 parts.
4. a preparation method for the Chinese medicine extract relieved the effect of alcohol, is characterized in that, the preparation method step of the described Chinese medicine extract relieved the effect of alcohol is as follows:
(1) get dry Fructus Tsaoko, carry out stirring extract after pulverizing with 60wt% ethanol water, centrifugal after extracting, getting the supernatant, is Fructus Tsaoko 60wt% ethanol-water extraction thing after concentrated;
(2) getting Semen Lablab Album, extract after pulverizing with ethyl acetate solution, filter, get filtrate after extracting, is Semen Lablab Album ethyl acetate extract after filtrate is concentrated;
(3) Radix Sophorae Flavescentis is pulverized, carry out stirring with pure water after pulverizing and extract, centrifugalize after extracting, after removing precipitation, supernatant concentration is obtained Radix Sophorae Flavescentis water extract;
(4) get dry Folium Baeckeae, by Folium Baeckeae mechanical activation comminution, the ethanol water pulverizing rear 80wt% extracts, centrifugal after extracting, and gets clear liquid and carries out vacuum concentration, and concentrate is the Folium Baeckeae 80wt% ethanol extraction of preparation;
(5) extracting carrying out stirring with ethanol after Cortex Magnoliae Officinalis pulverizing, leaving standstill after extracting, getting the Cortex Magnoliae Officinalis ethanol extract on upper strata, concentrating and obtain Cortex Magnoliae Officinalis ethanol extraction;
(6) Fructus Tsaoko 60wt% ethanol-water extraction thing 5-14 part, Semen Lablab Album ethyl acetate extract 3-9 part, Radix Sophorae Flavescentis water extract 4-8 part, Folium Baeckeae 80wt% ethanol extraction 5-10 part, Cortex Magnoliae Officinalis ethanol extraction 4-11 part is got by weight, above-mentioned each composition is mixed to evenly, for having the Chinese medicine extract of antialcoholism function.
5. the preparation method of a kind of Chinese medicine extract relieved the effect of alcohol according to claim 4, is characterized in that, when described Fructus Tsaoko extracts, Extracting temperature is 55 DEG C, and extraction time is 3h, and Fructus Tsaoko and 60wt% ethanol water weight ratio are 1:6.
6. the preparation method of a kind of Chinese medicine extract relieved the effect of alcohol according to claim 4, is characterized in that, when described Semen Lablab Album extracts, Extracting temperature is 50 DEG C, and extraction time is 5h, and Semen Lablab Album and ethyl acetate weight ratio are 1:10.
7. the preparation method of a kind of Chinese medicine extract relieved the effect of alcohol according to claim 4, is characterized in that, when described Folium Baeckeae extracts, Extracting temperature is 60 DEG C, and extraction time is 2h, and Folium Baeckeae and 80wt% ethanol weight ratio are 1:7.
8. the preparation method of a kind of Chinese medicine extract relieved the effect of alcohol according to claim 4, is characterized in that, when described Radix Sophorae Flavescentis extracts, Extracting temperature is room temperature, and extraction time is 6h, and Radix Sophorae Flavescentis and water weight ratio are 1:5.
9. the preparation method of a kind of Chinese medicine extract relieved the effect of alcohol according to claim 4, is characterized in that, when described Cortex Magnoliae Officinalis extracts, Extracting temperature is 40 DEG C, and extraction time is 6h, and Cortex Magnoliae Officinalis and ethanol weight ratio are 1:8.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2146939C1 (en) * | 1998-12-30 | 2000-03-27 | Пономарева Анна Геннадьевна | Method of treating alcoholism |
| CN101919802A (en) * | 2009-07-14 | 2010-12-22 | 无锡健而乐医药科技有限公司 | Solid effervescent mixture for the oral absorption |
| CN104056162A (en) * | 2013-03-21 | 2014-09-24 | 梅广浦 | Traditional Chinese medicine health care composition capable of dispelling effect of alcohol |
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2015
- 2015-02-06 CN CN201510061583.3A patent/CN104606623A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2146939C1 (en) * | 1998-12-30 | 2000-03-27 | Пономарева Анна Геннадьевна | Method of treating alcoholism |
| CN101919802A (en) * | 2009-07-14 | 2010-12-22 | 无锡健而乐医药科技有限公司 | Solid effervescent mixture for the oral absorption |
| CN104056162A (en) * | 2013-03-21 | 2014-09-24 | 梅广浦 | Traditional Chinese medicine health care composition capable of dispelling effect of alcohol |
Non-Patent Citations (2)
| Title |
|---|
| 陈裕等: "《新编中草药实用图典》", 31 May 2012, 农村读物出版社 * |
| 韦杨丽等: "《饮酒族营养食谱》", 30 November 2010, 广东人民出版社 * |
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Application publication date: 20150513 |
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