CN104606278A - Preparation method of external Zimiexuan tincture - Google Patents

Preparation method of external Zimiexuan tincture Download PDF

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Publication number
CN104606278A
CN104606278A CN201410843790.XA CN201410843790A CN104606278A CN 104606278 A CN104606278 A CN 104606278A CN 201410843790 A CN201410843790 A CN 201410843790A CN 104606278 A CN104606278 A CN 104606278A
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China
Prior art keywords
tincture
cercis chinensis
preparation
external
ethanol
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CN201410843790.XA
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Chinese (zh)
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张洛燕
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Individual
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Individual
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Priority to CN201410843790.XA priority Critical patent/CN104606278A/en
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Abstract

The invention discloses a preparation method of an external Zimiexuan tincture. The preparation method comprises the following steps: preparing a traditional Chinese medicine cercis chinensis into coarse powder; preparing the Zimiexuan tincture using the coarse powder of cercis chinensis and ethanol as a solvent according to an impregnation method, wherein the concentration is 20 g/100 ml; soaking for 7 days, filtering out a cercis chinensis tincture and removing dregs; adding benzoic acid, salicylic acid, lidocaine and 75% ethanol into the cercis chinensis tincture and storing at a room temperature. The cercis chinensis tincture prepared from the traditional Chinese medicine cercis chinensis is few in toxic and side effects and clear in curative effect; the dosage form is the tincture which can be applied to all parts of the body without greasy discomfortableness; being different from other tinctures, lidocaine is added to prevent pain stimulation of a skin lesion part due to decrustation during medicament; the production raw materials are wide in source, the production cost is low and the production process is simple; the medicine price can be lowered, and the medicinal burden of the nation can be alleviated. In addition, the tincture is easy to prepare, low in preparation cost and excellent in effect, so that the tincture is a drug which has an extremely good curative effect.

Description

The preparation method of the purple tinea tincture that goes out of a kind of external
Technical field
The invention belongs to purple to go out the preparing technical field of tinea tincture, particularly relate to a kind of external purple and to go out the preparation method of tinea tincture.
Background technology
Current antifungal medicine for external use mostly is breast, cream, cream type, and effective ingredient is Western medicine chemosynthesis, and price costly.Purple go out tinea tincture then with Chinese medicine Chinese medicine for raw material, formulated external-use tincture.Its sufficient raw of said preparation, inexpensive, cost of manufacture is extremely low, and processing technology is simple.This medicine will become ordinary people's effective essential drug at a low price.
The current medical market antifungal medicine for external use overwhelming majority used is Western medicine preparation, its defect: Western medicine toxic and side effects is large, and contraindication is many; Non-national enterprise product is many; Raw materials for production and process costs high, expensive, increase citizen medicine burden.Dosage form mostly is unguentum, and privileged sites (scalp, pudendum hirsutism position) drug use can not be smeared and be put in place.
And the antifungal tincture of external in the market, to having decortication, blister, rotten to the corn skin lesion to have strong pain stimulation sense, greatly reduces the compliance of patient's application.
Summary of the invention
The present invention is in order to the medicine price solving antimycotic in prior art is high, preparation complicated, less effective, and existing antifungal tincture is to the problem of the severe pain excitement of skin lesion, provides the preparation method of the purple tinea tincture that goes out of a kind of external.
In order to realize above-mentioned object, technical scheme of the present invention is: the preparation method of the purple tinea tincture that goes out of a kind of external, comprises the following steps:
Step one, Chinese medicine Cortex cercis chinensis is made as coarse powder;
Step 2, gets Cortex cercis chinensis coarse powder, by infusion process, does solvent produce with ethanol, and concentration is every 100 milliliters of Cortex cercis chinensiss 20 grams;
Step 3, soaks 7 days, leaches Cortex cercis chinensis tincture, reject medicinal residues;
Step 4, gets Cortex cercis chinensis tincture, adds benzoic acid, salicylic acid, lignocaine, 75% ethanol, room temperature preservation.
Preferably, in described step 2, solvent is 95% ethanol.
Preferably, in described step 3, leaching medicinal liquid is 20% Cortex cercis chinensis tincture.
Preferably, in described step 4, get 50 milliliters of Cortex cercis chinensis tinctures, add 6 grams, benzoic acid, salicylic acid 3 grams, lignocaine 0.02 gram, 75% ethanol add to 100 milliliters.
The preparation method of the purple tinea tincture that goes out of external provided by the invention, by adopting Chinese medicine Cortex cercis chinensis to produce Cortex cercis chinensis tincture, toxic and side effects is few, and curative effect is determined; Dosage form is tincture, and each position of whole body all can conveniently arrive, without greasy sense of discomfort; With other tinctures unlike: add lignocaine, can prevent cutaneous lesion because of peel cause medication time pain stimulation; Raw material sources is extensively luxuriant, and production cost is low, production technology is simple; Medical price can be reduced, alleviate national medical burden.In addition, the present invention is prepared simply, and preparation cost is low, excellent effect, is a kind of medicine of excellent treatment effect.
Accompanying drawing explanation
Fig. 1 shows the flow chart of the purple tinea tincture preparation method of going out of external of the present invention.
Detailed description of the invention
The technical problem solved to make the present invention, the technical scheme of employing, the technique effect easy to understand obtained, below in conjunction with concrete accompanying drawing, be described further the specific embodiment of the present invention.
The preparation method of the purple tinea tincture that goes out of external of the present invention, the preparation method of the purple tinea tincture that goes out of this external comprises the following steps:
Step one, Chinese medicine Cortex cercis chinensis is made as coarse powder;
Step 2, gets Cortex cercis chinensis coarse powder, by infusion process, does solvent produce with ethanol, and concentration is every 100 milliliters of Cortex cercis chinensiss 20 grams;
Step 3, soaks 7 days, leaches Cortex cercis chinensis tincture, reject medicinal residues;
Step 4, gets Cortex cercis chinensis tincture, adds benzoic acid, salicylic acid, lignocaine, 75% ethanol, room temperature preservation.
As a prioritization scheme of the embodiment of the present invention, in step 2, solvent is 95% ethanol.
As a prioritization scheme of the embodiment of the present invention, in step 3, leaching medicinal liquid is 20% Cortex cercis chinensis tincture.
As a prioritization scheme of the embodiment of the present invention, in step 4, get 50 milliliters of Cortex cercis chinensis tinctures, add 6 grams, benzoic acid, salicylic acid 3 grams, lignocaine 0.2 gram, 75% ethanol adds to 100 milliliters.
As described in Figure 1, the preparation method of the purple tinea tincture that goes out of the external of the embodiment of the present invention comprises the following steps:
S101: Chinese medicine Cortex cercis chinensis is made as coarse powder;
S102: get Cortex cercis chinensis coarse powder, by infusion process, does solvent with 95% ethanol and produces, concentration be every 100 milliliters suitable with Cortex cercis chinensis 20 grams;
S103: soak 7 days.Leaching medicinal liquid is 20% Cortex cercis chinensis tincture, reject medicinal residues;
S104: get 50 milliliters of Cortex cercis chinensis tinctures, add 6 grams, benzoic acid, salicylic acid 3 grams, lignocaine 0.2 gram, 75% ethanol add to 100 milliliters, room temperature: room temperature state; Air pressure: atmospheric pressure state;
The preparation method of the purple tinea tincture that goes out of external of the present invention, can treat clinical indication: tinea corporis, tinea cruris, tinea cruris, tinea pedis, tinea capitis, tinea unguium (immersion), tinea versicolor.Clinical efficacy: cure rate 98%, effective percentage 100%; Curative effect is determined; Cheap; With other tinctures unlike: add a small amount of anesthetis, can prevent cutaneous lesion because of peel cause medication time pain stimulation; Dosage form is convenient; National enterprise's Medical market competition power can be promoted; Single Chinese herbal medicine, production technology is simple.
The present invention is by preferred embodiment having carried out detailed explanation.But, by studying carefully above, concerning the change of each embodiment with to increase be apparent for one of ordinary skill in the art.Being intended that these changes all and increasing of applicant has all dropped in scope that the claims in the present invention protect.

Claims (4)

1. a preparation method for the purple tinea tincture that goes out of external, is characterized in that, comprise the following steps:
Step one, Chinese medicine Cortex cercis chinensis is made as coarse powder;
Step 2, gets Cortex cercis chinensis coarse powder, by infusion process, does solvent produce with ethanol, and concentration is every 100 milliliters of Cortex cercis chinensiss 20 grams;
Step 3, soaks 7 days, leaches Cortex cercis chinensis tincture, reject medicinal residues;
Step 4, gets Cortex cercis chinensis tincture, adds benzoic acid, salicylic acid, lignocaine, 75% ethanol, room temperature preservation.
2. the preparation method of the purple tinea tincture that goes out of external as claimed in claim 1, it is characterized in that: in described step 2, solvent is 95% ethanol.
3. the preparation method of the purple tinea tincture that goes out of external as claimed in claim 1, it is characterized in that: in described step 3, leaching medicinal liquid is 20% Cortex cercis chinensis tincture.
4. the preparation method of the purple tinea tincture that goes out of external as claimed in claim 1, it is characterized in that: in described step 4, get 50 milliliters of Cortex cercis chinensis tinctures, add 6 grams, benzoic acid, salicylic acid 3 grams, lignocaine 0.02 gram, 75% ethanol add to 100 milliliters.
CN201410843790.XA 2014-12-31 2014-12-31 Preparation method of external Zimiexuan tincture Pending CN104606278A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410843790.XA CN104606278A (en) 2014-12-31 2014-12-31 Preparation method of external Zimiexuan tincture

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Application Number Priority Date Filing Date Title
CN201410843790.XA CN104606278A (en) 2014-12-31 2014-12-31 Preparation method of external Zimiexuan tincture

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CN104606278A true CN104606278A (en) 2015-05-13

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1188409A (en) * 1995-06-07 1998-07-22 大正制药株式会社 Antifungal agent
CN1398628A (en) * 2002-08-09 2003-02-26 王心林 Itch-stopping bactericidal medicine and its prepn
CN103393744A (en) * 2013-07-22 2013-11-20 张洛燕 Preparation method of externally used purple tincture for eliminating tinea

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1188409A (en) * 1995-06-07 1998-07-22 大正制药株式会社 Antifungal agent
CN1398628A (en) * 2002-08-09 2003-02-26 王心林 Itch-stopping bactericidal medicine and its prepn
CN103393744A (en) * 2013-07-22 2013-11-20 张洛燕 Preparation method of externally used purple tincture for eliminating tinea

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
胥建中,等。: ""复方利多卡因乳膏止痛止痒效果观察"", 《华西医学》 *

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Application publication date: 20150513

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