CN104606127B - 靶向egfr的载铂类药物白蛋白纳米粒及其制备与应用 - Google Patents
靶向egfr的载铂类药物白蛋白纳米粒及其制备与应用 Download PDFInfo
- Publication number
- CN104606127B CN104606127B CN201510029918.3A CN201510029918A CN104606127B CN 104606127 B CN104606127 B CN 104606127B CN 201510029918 A CN201510029918 A CN 201510029918A CN 104606127 B CN104606127 B CN 104606127B
- Authority
- CN
- China
- Prior art keywords
- platinum
- egfr
- medicine
- albumin
- platinum medicine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Description
Claims (8)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510029918.3A CN104606127B (zh) | 2015-01-21 | 2015-01-21 | 靶向egfr的载铂类药物白蛋白纳米粒及其制备与应用 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510029918.3A CN104606127B (zh) | 2015-01-21 | 2015-01-21 | 靶向egfr的载铂类药物白蛋白纳米粒及其制备与应用 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104606127A CN104606127A (zh) | 2015-05-13 |
CN104606127B true CN104606127B (zh) | 2017-07-21 |
Family
ID=53140955
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510029918.3A Active CN104606127B (zh) | 2015-01-21 | 2015-01-21 | 靶向egfr的载铂类药物白蛋白纳米粒及其制备与应用 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104606127B (zh) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2020151727A1 (zh) * | 2019-01-23 | 2020-07-30 | 锐创生物医药(香港)有限公司 | 药物复合物及其制备方法和用途 |
CN112961188B (zh) * | 2021-02-07 | 2022-10-04 | 山东省第二人民医院(山东省耳鼻喉医院、山东省耳鼻喉研究所) | 一种四价铂前药苄达酸铂、其制剂及制备方法和应用 |
CN115105605B (zh) * | 2021-03-17 | 2023-09-08 | 四川大学 | 一种主动靶向的抗肿瘤自组装纳米粒的制备及其应用 |
CN114163481B (zh) * | 2021-12-06 | 2023-06-23 | 郑州大学 | 一种含铂类药物纳米囊泡及其制备方法与应用 |
CN114404611B (zh) * | 2022-01-05 | 2023-11-07 | 南方医科大学 | 一种酶动力蛋白马达的制备方法及应用 |
CN114712486B (zh) * | 2022-04-08 | 2023-12-12 | 南方医科大学 | 一种环五肽纳米制剂及其制备方法和应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE10209821A1 (de) * | 2002-03-06 | 2003-09-25 | Biotechnologie Ges Mittelhesse | Kopplung von Proteinen an ein modifiziertes Polysaccharid |
CN101822838B (zh) * | 2009-03-05 | 2012-06-27 | 无锡纳奥生物医药有限公司 | 靶向识别肿瘤细胞的纳米药物载体材料及其制备和应用 |
CN101708337B (zh) * | 2009-08-18 | 2011-08-10 | 上海交通大学医学院附属新华医院 | 一种包载奥沙利铂的人血白蛋白纳米粒的制备方法 |
JPWO2011046193A1 (ja) * | 2009-10-16 | 2013-03-07 | 国立大学法人東京海洋大学 | ウイルス性出血性敗血症ウイルス結合性アプタマー |
-
2015
- 2015-01-21 CN CN201510029918.3A patent/CN104606127B/zh active Active
Also Published As
Publication number | Publication date |
---|---|
CN104606127A (zh) | 2015-05-13 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN104606127B (zh) | 靶向egfr的载铂类药物白蛋白纳米粒及其制备与应用 | |
Peng et al. | Herceptin-conjugated paclitaxel loaded PCL-PEG worm-like nanocrystal micelles for the combinatorial treatment of HER2-positive breast cancer | |
Zhang et al. | Antitumor effect of hyaluronic-acid-modified chitosan nanoparticles loaded with siRNA for targeted therapy for non-small cell lung cancer | |
Belhadj et al. | Multifunctional targeted liposomal drug delivery for efficient glioblastoma treatment | |
Sun et al. | Chitosan-based nanoparticles for survivin targeted siRNA delivery in breast tumor therapy and preventing its metastasis | |
Daniels et al. | Sterically stabilized siRNA: gold nanocomplexes enhance c-MYC silencing in a breast cancer cell model | |
Song et al. | Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy | |
Ke et al. | Synergistic dual-modified liposome improves targeting and therapeutic efficacy of bone metastasis from breast cancer | |
CN100509059C (zh) | 磁热疗用纳米磁粉-抗cea抗体靶向药物 | |
CN106794164A (zh) | 脂质体包封的亲和性药物 | |
Bian et al. | Anti-EGFR-iRGD recombinant protein conjugated silk fibroin nanoparticles for enhanced tumor targeting and antitumor efficiency | |
US9371364B2 (en) | Dual-targeted therapeutic peptide for nasopharyngeal carcinoma, nanoparticles carrying same and uses thereof | |
Chen et al. | Aptamer functionalized cisplatin-albumin nanoparticles for targeted delivery to epidermal growth factor receptor positive cervical cancer | |
Li et al. | Captopril-polyethyleneimine conjugate modified gold nanoparticles for co-delivery of drug and gene in anti-angiogenesis breast cancer therapy | |
Zhao et al. | A novel nanoparticle drug delivery system based on PEGylated hemoglobin for cancer therapy | |
CN105476975B (zh) | 主动靶向型抗脑肿瘤药物及其制备方法 | |
Cui et al. | Dual-modified natural high density lipoprotein particles for systemic glioma-targeting drug delivery | |
Brar et al. | Tyrosine kinase inhibitors for glioblastoma multiforme: challenges and opportunities for drug delivery | |
CN101897982A (zh) | 治疗癌症的siRNA药物组合物 | |
CN107019673A (zh) | 一种具有肿瘤主动靶向功能的紫杉醇脂质体制剂及其制备方法和应用 | |
Zhao et al. | Targeting delivery of partial VAR2CSA peptide guided N-2-Hydroxypropyl trimethyl ammonium chloride chitosan nanoparticles for multiple cancer types | |
Nagpal et al. | Targeted therapies against breast cancer: Clinical perspectives, obstacles and new opportunities | |
CN107007550B (zh) | 一种氧化还原响应性两亲性共聚物及其制备方法和应用 | |
Wang et al. | pH-responsive sulfated hyaluronic acid nanoparticles targeting tumor cells and CAFs for the treatment of breast cancer | |
Duan et al. | The synergistic antitumor activity of 3-(2-nitrophenyl) propionic acid-paclitaxel nanoparticles (NPPA-PTX NPs) and anti-PD-L1 antibody inducing immunogenic cell death |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20190219 Address after: 214000 No. 88, Meiliang West Road, Mashan, Binhu District, Wuxi City, Jiangsu Province Patentee after: Wuxi Naao Bio-Pharm Co., Ltd. Address before: 314050 No. 101, Block C, Jiaxing Science and Technology City Complex Building, 3339 Linggongtang Road, Nanhu District, Jiaxing City, Zhejiang Province Patentee before: Zhejiang Fengsheng Biological Engineering Co., Ltd. |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20210204 Address after: Room 102, building 2, 947 Jinle Road, Baoshan District, Shanghai, 200941 Patentee after: Shanghai Nao Biotechnology Co.,Ltd. Address before: 214000 No. 88, Meiliang West Road, Mashan, Binhu District, Wuxi City, Jiangsu Province Patentee before: WUXI FOXGENE Co.,Ltd. |