CN104605373A - 营养补充剂及其制备的压片糖果 - Google Patents
营养补充剂及其制备的压片糖果 Download PDFInfo
- Publication number
- CN104605373A CN104605373A CN201510094382.3A CN201510094382A CN104605373A CN 104605373 A CN104605373 A CN 104605373A CN 201510094382 A CN201510094382 A CN 201510094382A CN 104605373 A CN104605373 A CN 104605373A
- Authority
- CN
- China
- Prior art keywords
- astaxanthin
- buckthorn
- sea
- hoveniae semoveniae
- semoveniae semen
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 235000009508 confectionery Nutrition 0.000 title claims abstract description 24
- 235000015872 dietary supplement Nutrition 0.000 title abstract description 11
- JEBFVOLFMLUKLF-IFPLVEIFSA-N Astaxanthin Natural products CC(=C/C=C/C(=C/C=C/C1=C(C)C(=O)C(O)CC1(C)C)/C)C=CC=C(/C)C=CC=C(/C)C=CC2=C(C)C(=O)C(O)CC2(C)C JEBFVOLFMLUKLF-IFPLVEIFSA-N 0.000 claims abstract description 39
- 235000013793 astaxanthin Nutrition 0.000 claims abstract description 39
- MQZIGYBFDRPAKN-ZWAPEEGVSA-N astaxanthin Chemical compound C([C@H](O)C(=O)C=1C)C(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)C(=O)[C@@H](O)CC1(C)C MQZIGYBFDRPAKN-ZWAPEEGVSA-N 0.000 claims abstract description 39
- 229940022405 astaxanthin Drugs 0.000 claims abstract description 39
- 239000001168 astaxanthin Substances 0.000 claims abstract description 39
- 241000229143 Hippophae Species 0.000 claims abstract description 34
- 235000003145 Hippophae rhamnoides Nutrition 0.000 claims abstract description 34
- 210000000582 semen Anatomy 0.000 claims description 33
- 235000008935 nutritious Nutrition 0.000 claims description 27
- 239000004615 ingredient Substances 0.000 claims description 15
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 12
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 claims description 11
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 11
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 10
- 239000000463 material Substances 0.000 claims description 10
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 10
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 10
- 239000000843 powder Substances 0.000 claims description 8
- 239000003094 microcapsule Substances 0.000 claims description 6
- 239000004480 active ingredient Substances 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 20
- 230000003064 anti-oxidating effect Effects 0.000 abstract description 7
- 230000036039 immunity Effects 0.000 abstract description 4
- 230000003859 lipid peroxidation Effects 0.000 abstract description 4
- 235000015097 nutrients Nutrition 0.000 abstract description 2
- 235000016709 nutrition Nutrition 0.000 abstract description 2
- 230000002195 synergetic effect Effects 0.000 abstract 1
- 239000003963 antioxidant agent Substances 0.000 description 14
- 230000003078 antioxidant effect Effects 0.000 description 14
- 235000006708 antioxidants Nutrition 0.000 description 14
- 238000012360 testing method Methods 0.000 description 9
- 238000004458 analytical method Methods 0.000 description 8
- 230000002000 scavenging effect Effects 0.000 description 6
- 238000002156 mixing Methods 0.000 description 5
- 230000003647 oxidation Effects 0.000 description 5
- 238000007254 oxidation reaction Methods 0.000 description 5
- 238000002360 preparation method Methods 0.000 description 5
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 description 4
- 230000001419 dependent effect Effects 0.000 description 4
- 238000007689 inspection Methods 0.000 description 4
- 230000002929 anti-fatigue Effects 0.000 description 3
- 238000009826 distribution Methods 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000013642 negative control Substances 0.000 description 3
- 238000001543 one-way ANOVA Methods 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- LXEKPEMOWBOYRF-QDBORUFSSA-N AAPH Chemical compound Cl.Cl.NC(=N)C(C)(C)\N=N\C(C)(C)C(N)=N LXEKPEMOWBOYRF-QDBORUFSSA-N 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 206010062717 Increased upper airway secretion Diseases 0.000 description 2
- 208000004880 Polyuria Diseases 0.000 description 2
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 description 2
- GLEVLJDDWXEYCO-UHFFFAOYSA-N Trolox Chemical compound O1C(C)(C(O)=O)CCC2=C1C(C)=C(C)C(O)=C2C GLEVLJDDWXEYCO-UHFFFAOYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 239000011149 active material Substances 0.000 description 2
- 230000002605 anti-dotal effect Effects 0.000 description 2
- 208000006673 asthma Diseases 0.000 description 2
- 238000011088 calibration curve Methods 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 235000012000 cholesterol Nutrition 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 239000000470 constituent Substances 0.000 description 2
- 238000013461 design Methods 0.000 description 2
- 238000010790 dilution Methods 0.000 description 2
- 239000012895 dilution Substances 0.000 description 2
- NJDNXYGOVLYJHP-UHFFFAOYSA-L disodium;2-(3-oxido-6-oxoxanthen-9-yl)benzoate Chemical class [Na+].[Na+].[O-]C(=O)C1=CC=CC=C1C1=C2C=CC(=O)C=C2OC2=CC([O-])=CC=C21 NJDNXYGOVLYJHP-UHFFFAOYSA-L 0.000 description 2
- 230000035619 diuresis Effects 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 229930003935 flavonoid Natural products 0.000 description 2
- 150000002215 flavonoids Chemical class 0.000 description 2
- 235000017173 flavonoids Nutrition 0.000 description 2
- 239000000796 flavoring agent Substances 0.000 description 2
- 235000019634 flavors Nutrition 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- 230000001077 hypotensive effect Effects 0.000 description 2
- IYRMWMYZSQPJKC-UHFFFAOYSA-N kaempferol Chemical compound C1=CC(O)=CC=C1C1=C(O)C(=O)C2=C(O)C=C(O)C=C2O1 IYRMWMYZSQPJKC-UHFFFAOYSA-N 0.000 description 2
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 2
- OPMNROCQHKJDAQ-FKSUSPILSA-N loline Chemical compound C1C[C@@H]2O[C@H]3[C@H](NC)[C@@H]2N1C3 OPMNROCQHKJDAQ-FKSUSPILSA-N 0.000 description 2
- 208000026435 phlegm Diseases 0.000 description 2
- 230000000630 rising effect Effects 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 241000195493 Cryptophyta Species 0.000 description 1
- 241001269238 Data Species 0.000 description 1
- UBSCDKPKWHYZNX-UHFFFAOYSA-N Demethoxycapillarisin Natural products C1=CC(O)=CC=C1OC1=CC(=O)C2=C(O)C=C(O)C=C2O1 UBSCDKPKWHYZNX-UHFFFAOYSA-N 0.000 description 1
- 206010013954 Dysphoria Diseases 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- GQODBWLKUWYOFX-UHFFFAOYSA-N Isorhamnetin Natural products C1=C(O)C(C)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 GQODBWLKUWYOFX-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 235000000404 Poncirus trifoliata Nutrition 0.000 description 1
- 244000202052 Poncirus trifoliata Species 0.000 description 1
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 description 1
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 description 1
- 208000034189 Sclerosis Diseases 0.000 description 1
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical compound [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 description 1
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 description 1
- 206010047700 Vomiting Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 230000003712 anti-aging effect Effects 0.000 description 1
- 230000003026 anti-oxygenic effect Effects 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000004556 brain Anatomy 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 235000021466 carotenoid Nutrition 0.000 description 1
- 150000001747 carotenoids Chemical class 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 230000001934 delay Effects 0.000 description 1
- 230000006866 deterioration Effects 0.000 description 1
- ZPWVASYFFYYZEW-UHFFFAOYSA-L dipotassium hydrogen phosphate Chemical compound [K+].[K+].OP([O-])([O-])=O ZPWVASYFFYYZEW-UHFFFAOYSA-L 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005538 encapsulation Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- OPMNROCQHKJDAQ-UHFFFAOYSA-N festucine Natural products C1CC2OC3C(NC)C2N1C3 OPMNROCQHKJDAQ-UHFFFAOYSA-N 0.000 description 1
- 229930003944 flavone Natural products 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 235000011949 flavones Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 229930182478 glucoside Natural products 0.000 description 1
- 150000008131 glucosides Chemical class 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229930186938 hovenoside Natural products 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 235000008800 isorhamnetin Nutrition 0.000 description 1
- IZQSVPBOUDKVDZ-UHFFFAOYSA-N isorhamnetin Chemical compound C1=C(O)C(OC)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 IZQSVPBOUDKVDZ-UHFFFAOYSA-N 0.000 description 1
- 235000008777 kaempferol Nutrition 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000027939 micturition Effects 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 229910000403 monosodium phosphate Inorganic materials 0.000 description 1
- 235000019799 monosodium phosphate Nutrition 0.000 description 1
- UXOUKMQIEVGVLY-UHFFFAOYSA-N morin Natural products OC1=CC(O)=CC(C2=C(C(=O)C3=C(O)C=C(O)C=C3O2)O)=C1 UXOUKMQIEVGVLY-UHFFFAOYSA-N 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 206010036067 polydipsia Diseases 0.000 description 1
- SVICABYXKQIXBM-UHFFFAOYSA-L potassium malate Chemical compound [K+].[K+].[O-]C(=O)C(O)CC([O-])=O SVICABYXKQIXBM-UHFFFAOYSA-L 0.000 description 1
- 235000011033 potassium malate Nutrition 0.000 description 1
- 239000001415 potassium malate Substances 0.000 description 1
- 235000013406 prebiotics Nutrition 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 235000005875 quercetin Nutrition 0.000 description 1
- 229960001285 quercetin Drugs 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000003507 refrigerant Substances 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 238000009938 salting Methods 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- AJPJDKMHJJGVTQ-UHFFFAOYSA-M sodium dihydrogen phosphate Chemical compound [Na+].OP(O)([O-])=O AJPJDKMHJJGVTQ-UHFFFAOYSA-M 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000002904 solvent Substances 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 210000002435 tendon Anatomy 0.000 description 1
- 239000011573 trace mineral Substances 0.000 description 1
- 235000013619 trace mineral Nutrition 0.000 description 1
- 210000001835 viscera Anatomy 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000019155 vitamin A Nutrition 0.000 description 1
- 239000011719 vitamin A Substances 0.000 description 1
- 229940045997 vitamin a Drugs 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- 230000008673 vomiting Effects 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
- A23G3/48—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing plants or parts thereof, e.g. fruits, seeds, extracts
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23G—COCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
- A23G3/00—Sweetmeats; Confectionery; Marzipan; Coated or filled products
- A23G3/34—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
- A23G3/36—Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Inorganic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Botany (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
本发明涉及一种营养补充剂,属于营养物领域;本发明的有效成分为虾青素、沙棘和枳椇子,同时提供一种采用所述营养补充剂制备的压片糖果。本发明可提高抗氧化能力、清除自由基、提高免疫力,是具有营养价值的膳食补充剂;虾青素、沙棘和枳椇子协同抗氧化和防止脂质过氧化的作用效果大于单独成分所起作用,合适比例的配比在抗氧化方面起到大于加和作用的效果。
Description
技术领域
本发明涉及一种营养补充剂,尤其涉及一种含虾青素、沙棘和枳椇子的营养补充剂,属于营养物。
背景技术
随着人们健康意识的不断提高,更加注重营养与品质,然而现代人工作压力大、环境恶化,导致体内自由基过多,机体衰老现象严重、代谢发生异常、肠道菌群失衡、蠕动减慢、免疫功能下降。虾青素可以清除体内自由基、延缓衰老、有益关节、增强免疫力、有益眼睛和大脑、增强耐力、抗衰老;沙棘具有清除自由基、抗衰老的作用,含有多种生物活性物质,具有抗疲劳、增强机体活力等功效,含有黄酮物质,具有止咳、平喘祛痰、降低胆固醇的作用;枳椇子具有显著利尿和降压作用,有抗脂质过氧化作用和增强耐寒耐热功能。
目前市场上的压片糖果制品多以单一的清凉口感,润喉片剂为主,综合抗氧化和清除自由基提高免疫力的压片糖果较少,将虾青素、沙棘和枳椇子结合制备的压片糖果更无相关文献报道。
发明内容
本发明的目的在于提供一种营养补充剂,用于提高抗氧化能力、清除自由基、提高免疫力;本发明同时提供采用所述营养补充剂制备的压片糖果。
所述营养补充剂的有效成分为虾青素、沙棘和枳椇子。
所述营养补充剂,各组分重量份配比为:虾青素0.1-5、沙棘0.1-10、枳椇子0.1-10。
所述营养补充剂,优选各组分重量份配比为:虾青素0.5-3、沙棘0.5-5、枳椇子0.5-5。
所述营养补充剂,更优选各组分重量份配比为:虾青素0.6-2.5、沙棘0.6-3、枳椇子0.6-3。
所述营养补充剂,最优选各组分重量份配比为:虾青素0.9、沙棘1.2、枳椇子1.2。
一种采用所述营养补充剂制备的压片糖果,还包括辅料,辅料为:山梨糖醇、香精、硬脂酸镁和羧甲基纤维素钠。
所述压片糖果,各组分重量份配比为:虾青素0.1-5、沙棘0.1-10、枳椇子0.1-10、山梨糖醇50-90、香精0.1-10、硬脂酸镁0.1-10和羧甲基纤维素钠0.1-10。
所述压片糖果,优选各组分重量份配比为:虾青素0.6-2.5、沙棘0.6-3、枳椇子0.6-3、山梨糖醇50-90、香精0.1-10、硬脂酸镁0.1-10和羧甲基纤维素钠0.1-10。
所述营养补充剂制备的压片糖果的制备方法,包括配料和压片两步:
1、配料
(1)烘料:固体山梨糖醇烘干去除水分后使用;把山梨糖醇放入CT-1A型热风循环烘箱中烘干,温度设定为60℃,烘料时间两个小时;
(2)称量:按期校对计量器具,操作人员要一人称量,一人复核,称量时要避免不同的原辅料混淆;
(3)混料:将称量好的原辅料加入CH-100型混合机内混料10分钟,然后采用喷淋式方法加入香精混料15分钟,停机密闭45分钟后,取出用40目筛网过筛一遍,加入硬脂酸镁后再混料10分钟;
2、压片:
(1)片剂要求外观完整、光滑、不得有可见异物,不得有松片和裂片;片重差异不大于±5%;压片时片剂的硬度要合理掌握,既要保证压片机的安全,又要保证糖片硬度较好;
(2)包衣:采用羟甲基纤维素钠作为包膜剂,对压片糖果进行包膜处理;
(3)灭菌:将制好的片剂放在紫外线下照射10-20min。
上述营养补充剂和压片糖果中,由于虾青素在空气中极易氧化,因此将虾青素制成虾青素微囊粉参加配制,沙棘和枳椇子以采用粉末状原料为宜。
本发明中山梨糖醇起到甜味剂的作用,香精起到呈味作用,硬脂酸镁起到抗粘剂作用,羧甲基纤维素钠起到包被作用。
虾青素(Astaxanthin)是一种膳食营养补充剂,属于类胡萝卜素,普遍存在于很多植物尤其是藻类、浮游植物中,也存在于少数细菌和真菌中;具有抗氧化、清除自由基、阻止脂质过氧化、延缓衰老、预防和抑制癌症、预防动脉硬化、增强免疫力、维护眼睛和中枢神经系统健康等作用。
沙棘(Prebiotics)也是一种膳食营养补充剂,营养丰富,含有多种维生素、微量元素、黄酮、超氧化物类活性物质和人体所需的各种氨基酸,具有清除自由基、抗衰老的作用;其中所含的多种生物活性物质、大量的维生素E、维生素A等,具有抗疲劳、增强机体活力等功效,含有的异鼠李素及其糖甙、槲皮素、山奈酚等黄酮物质,具有止咳、平喘祛痰和降低胆固醇的作用。
枳椇子是一种膳食营养补充剂,枳椇性味甘酸平,具有清热、止烦渴、补中益气、润五脏、舒筋络的功效;用于治醉酒、烦热、口渴、呕吐、二便不利;其中所含的黑麦草碱、枳椇苷、苹果酸钾等物质,有显著利尿和降压作用,枳椇子匀浆液有抗脂质过氧化作用和增强耐寒耐热功能。
虾青素、沙棘和枳椇子三者具有协同抗氧化、防止脂质过氧化作用,所含活性物质具有共同抗疲劳、增强机体活力的功效,三者合用的效果大于单独成分所起作用,合适比例的配比在抗氧化方面起到大于加和作用的效果。
与现有技术相比,本发明的有益效果在于:
(1)本发明所述的营养补充剂可提高抗氧化能力、清除自由基、提高免疫力,是具有营养价值的膳食补充剂。
(2)虾青素、沙棘和枳椇子协同抗氧化和防止脂质过氧化的作用效果大于单独成分所起作用,合适比例的配比在抗氧化方面起到大于加和作用的效果。
具体实施方式
以下结合营养补充剂的抗氧化作用实验和压片糖果的实施例对本发明进行详实的阐述。
营养补充剂的抗氧化作用试验
1.材料和方法
虾青素微囊粉、沙棘粉、枳椇子粉,试验时以蒸馏水作溶剂配制受试物。
2仪器与试剂
2.1仪器:酶标仪、万分之一天平、96孔微孔板、移液枪;玻璃器皿:容量瓶若干、烧杯、移液管。
2.2试剂:磷酸氢二钾、磷酸二氢钠、荧光素二钠盐、Trolox标准物质、AAPH溶液和双蒸水。
3样品测定
如表1所示,其中:A代表虾青素,B代表沙棘,C代表枳椇子;采用SPSS做正交试验设计的三因素三水平试验方案设置9组实验数据,即试验号1-9,另设置阴性对照组10、11和12;表中A、B、C的数据指各组分的重量份,根据发明内容中提供的重量份配比选取,其中:A取0.3、0.6和0.9共计3个重量份分布,B取0.6、0.9和1.2共计3个重量份分布,C取1.2、1.5和1.8共计3个重量份分布。
分别取1-9组样品、阴性对照组10、11和12的样品以及标准抗氧化物(Trolox),用磷酸钾缓冲液对其进行稀释,分别取稀释液各20μL,分别与160μL荧光素二钠盐溶液混合后,在37℃下保温30min,然后再加入AAPH溶液20μL,迅速开始测定,使用酶标仪记录荧光信号,得到抗氧化剂浓度与荧光信号强度的标准曲线,各样品的抗氧化指数(ORAC)由标准曲线得到;值得注意的是,最终得到的抗氧化指数(ORAC)的结果(详见表1)与样品的稀释度无关,仅与各组分之间的相对浓度有关。
表1 L9(34)正交试验设计表
试验号 | A | B | C | ORAC |
1 | 0.9 | 1.2 | 1.2 | 621.3 |
2 | 0.3 | 0.9 | 1.8 | 217.3 |
3 | 0.9 | 0.6 | 1.8 | 533 |
4 | 0.3 | 1.2 | 1.5 | 230 |
5 | 0.6 | 1.2 | 1.8 | 411 |
6 | 0.9 | 0.9 | 1.5 | 508.4 |
7 | 0.6 | 0.9 | 1.2 | 351.4 |
8 | 0.6 | 0.6 | 1.5 | 316.6 |
9 | 0.3 | 0.6 | 1.2 | 209.5 |
10 | 0.3 | 0 | 0 | 185.3 |
11 | 0 | 0.6 | 0 | 163.5 |
12 | 0 | 0 | 1.2 | 133.3 |
4数据统计分析
采用SPSS17.0统计软件进行单因素方差分析(One-Way ANOVA),单处理之间的差异显著(P<0.05)时,用Dunan's检验进行多重比较分析。
5结果与分析
表2 单因素方差分析表
平方和 | 自由度 | 均方 | F | 显著性 | |
组间 | 545729.847 | 8 | 68216.231 | 2056.702 | .000 |
组内 | 597.020 | 18 | 33.168 | ||
总数 | 546326.867 | 26 |
由表2可得,组间F检验的p值<0.05,表明不同配比的组合间的差异性达到极显著,具有统计意义,可以进行统计分析。
表3 组间多重比较方差分析
将显示同类子集中的组均值。
a.将使用调和均值样本大小=3.000。
由表3可得,组合之间的差异显著(P<0.05)时,用Dunan's检验进行多重比较分析,在0.05水平下组合间的多重比较中,10、11、12阴性对照组与1-9试验号组合的配比有显著差异,表明虾青素、沙棘和枳椇子在抗氧化方面具有协同作用;试验号2,4和4,9比较结果不具有显著性,表明此两组的因素水平配比的抗氧化性能没有差异性,其他因素水平的配比比较结果具有显著性,表明在0.05水平下组合的抗氧化具有差异性。
表4 A虾青素三组数据在置信区间结果分析
因变量:Result
由表4可得A虾青素的三组数据在正交试验测定ORAC指数后,经软件统计分析得出的抗氧化水平,由表4得出0.9>0.6>0.3,表明随虾青素含量提高,抗氧化能力在上升,在选择组合配置中,以A取0.9重量份为宜。
表5 B沙棘三组数据在置信区间结果分析
因变量:Result
由表5可得B沙棘的三组数据在正交试验测定ORAC指数后,经软件统计分析得出的抗氧化水平,由表5得出1.2>0.9>0.6,表明随沙棘含量提高,抗氧化能力在上升,在选择组合配置中,以B取1.2重量份为宜。
表6 C枳椇子三组数据在置信区间结果分析
因变量:Result
由表6可得C枳椇子的三组数据在正交试验测定ORAC指数后,经软件统计分析得出的抗氧化水平,由表6得出1.2>1.8>1.5,表明随枳椇子含量提高,抗氧化能力有所下降,在选择组合配置中,以C取1.2重量份为宜。
表7 主体间效应的检验参数
因变量:Result
源 | III型平方和 | df | 均方 | F | Sig. |
校正模型 | 181624.773a | 6 | 30270.796 | 212.296 | .005 |
截距 | 1283311.361 | 1 | 1283311.361 | 9000.150 | .000 |
A | 170088.149 | 2 | 85044.074 | 596.433 | .002 |
B | 8434.809 | 2 | 4217.404 | 29.578 | .033 |
C | 3101.816 | 2 | 1550.908 | 10.877 | .084 |
误差 | 285.176 | 2 | 142.588 | ||
总计 | 1465221.310 | 9 | |||
校正的总计 | 181909.949 | 8 |
a.R方=.998(调整R方=.994)
从表7可得,各因素对试验结果的重要次序为A>B>C,由F检验结果(P<0.05)可得,虾青素对抗氧化作用有极显著影响,沙棘和枳椇子对抗氧化指标影响显著性影响(P<0.05),结合表4、5、6可得,虾青素、沙棘和枳椇子在组合条件下,对抗氧化作用的效果以A取0.9重量份,B取1.2重量份,C取1.2重量份为宜,可得本发明所述营养补充剂,最佳配方比为A:B:C=0.9:1.2:1.2。
压片糖果实施例1
所述压片糖果,各组分重量份配比为:虾青素微囊粉5、沙棘8、枳椇子4、山梨糖醇64、香精8、硬脂酸镁5和羧甲基纤维素钠6。
压片糖果实施例2
所述压片糖果中,各组分重量份配比为:虾青素微囊粉2.5、沙棘3、枳椇子1、山梨糖醇78.5、香精5、硬脂酸镁5和羧甲基纤维素钠5。
压片糖果实施例3
所述压片糖果中,各组分重量份配比为:虾青素微囊粉0.9、沙棘1.2、枳椇子1.2、山梨糖醇84.7、香精2、硬脂酸镁5和羧甲基纤维素钠5。
Claims (9)
1.一种营养补充剂,其特征在于,有效成分为虾青素、沙棘和枳椇子。
2.根据权利要求1所述的营养补充剂,其特征在于,各组分重量份配比为:虾青素0.1-5、沙棘0.1-10、枳椇子0.1-10。
3.根据权利要求1所述的营养补充剂,其特征在于,各组分重量份配比为:虾青素0.5-3、沙棘0.5-5、枳椇子0.5-5。
4.根据权利要求1所述的营养补充剂,其特征在于,各组分重量份配比为:虾青素0.6-2.5、沙棘0.6-3、枳椇子0.6-3。
5.根据权利要求1所述的营养补充剂,其特征在于,各组分重量份配比为:虾青素0.9、沙棘1.2、枳椇子1.2。
6.根据权利要求1所述的营养补充剂,其特征在于,虾青素采用虾青素微囊粉。
7.一种采用权利要求1-6任一所述营养补充剂制备的压片糖果,其特征在于,还包括辅料,辅料为:山梨糖醇、香精、硬脂酸镁和羧甲基纤维素钠。
8.根据权利要求7所述营养补充剂制备的压片糖果,其特征在于,各组分重量份配比为:虾青素0.1-5、沙棘0.1-10、枳椇子0.1-10、山梨糖醇50-90、香精0.1-10、硬脂酸镁0.1-10和羧甲基纤维素钠0.1-10。
9.根据权利要求7所述营养补充剂制备的压片糖果,其特征在于,各组分重量份配比为:虾青素0.6-2.5、沙棘0.6-3、枳椇子0.6-3、山梨糖醇50-90、香精0.1-10、硬脂酸镁0.1-10和羧甲基纤维素钠0.1-10。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510094382.3A CN104605373B (zh) | 2015-03-03 | 2015-03-03 | 营养补充剂及其制备的压片糖果 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510094382.3A CN104605373B (zh) | 2015-03-03 | 2015-03-03 | 营养补充剂及其制备的压片糖果 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104605373A true CN104605373A (zh) | 2015-05-13 |
CN104605373B CN104605373B (zh) | 2017-01-18 |
Family
ID=53140250
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201510094382.3A Expired - Fee Related CN104605373B (zh) | 2015-03-03 | 2015-03-03 | 营养补充剂及其制备的压片糖果 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104605373B (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106993708A (zh) * | 2017-06-07 | 2017-08-01 | 安徽杨氏保健茶科技有限公司 | 一种增强免疫力的固体保健茶及其加工方法 |
CN109965068A (zh) * | 2017-12-27 | 2019-07-05 | 上海梓惜生物技术有限公司 | 一种苦瓜蛹虫草压片糖果及其制备方法 |
CN111616372A (zh) * | 2020-06-08 | 2020-09-04 | 威海希维斯生物科技有限公司 | 一种航海人员用的胶原蛋白肽片剂及其制备方法 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101011170A (zh) * | 2006-11-07 | 2007-08-08 | 北京汉潮联创中药科技有限公司 | 一种解酒植物饮料及其配制方法 |
DE202009013422U1 (de) * | 2009-08-22 | 2010-03-04 | Gavrilovic, Rade | Astaxanthin |
JP2014000007A (ja) * | 2012-06-15 | 2014-01-09 | Yawata Bussan Kk | カプセル状食品 |
CN103829234A (zh) * | 2013-12-25 | 2014-06-04 | 无锡市天赐康生物科技有限公司 | 一种提高免疫力降血脂的保健食品及其制备方法 |
CN104644794A (zh) * | 2015-01-23 | 2015-05-27 | 广州善康生物科技有限公司 | 一种治疗肿块的药物 |
-
2015
- 2015-03-03 CN CN201510094382.3A patent/CN104605373B/zh not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101011170A (zh) * | 2006-11-07 | 2007-08-08 | 北京汉潮联创中药科技有限公司 | 一种解酒植物饮料及其配制方法 |
DE202009013422U1 (de) * | 2009-08-22 | 2010-03-04 | Gavrilovic, Rade | Astaxanthin |
JP2014000007A (ja) * | 2012-06-15 | 2014-01-09 | Yawata Bussan Kk | カプセル状食品 |
CN103829234A (zh) * | 2013-12-25 | 2014-06-04 | 无锡市天赐康生物科技有限公司 | 一种提高免疫力降血脂的保健食品及其制备方法 |
CN104644794A (zh) * | 2015-01-23 | 2015-05-27 | 广州善康生物科技有限公司 | 一种治疗肿块的药物 |
Non-Patent Citations (1)
Title |
---|
王艳林等: "枳椇子抗脂质过氧化作用的实验研究", 《中草药》, 15 June 1994 (1994-06-15) * |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106993708A (zh) * | 2017-06-07 | 2017-08-01 | 安徽杨氏保健茶科技有限公司 | 一种增强免疫力的固体保健茶及其加工方法 |
CN109965068A (zh) * | 2017-12-27 | 2019-07-05 | 上海梓惜生物技术有限公司 | 一种苦瓜蛹虫草压片糖果及其制备方法 |
CN111616372A (zh) * | 2020-06-08 | 2020-09-04 | 威海希维斯生物科技有限公司 | 一种航海人员用的胶原蛋白肽片剂及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
CN104605373B (zh) | 2017-01-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Batista et al. | Red-jambo (Syzygium malaccense): Bioactive compounds in fruits and leaves | |
Narwojsz et al. | Fruit physical features, phenolic compounds profile and inhibition activities of cranberry cultivars (Vaccinium macrocarpon) compared to wild-grown cranberry (Vaccinium oxycoccus) | |
Domínguez‐Valhondo et al. | Influence of the commercial processing and floral origin on bioactive and nutritional properties of honeybee‐collected pollen | |
Abreu et al. | Antioxidant capacity, phenolic compound content and sensory properties of cookies produced from organic grape peel (Vitis labrusca) flour | |
Pandey et al. | Proximate and mineral composition of Kadamba (Neolamarckia cadamba) fruit and its use in the development of nutraceutical enriched beverage | |
CN104770636A (zh) | 含虾青素和益生元的营养补充剂及其制备的压片糖果 | |
Mendes et al. | Microencapsulation of jabuticaba extracts (Myrciaria cauliflora): Evaluation of their bioactive and thermal properties in cassava starch biscuits | |
Charoenphun et al. | Antioxidant and anti-inflammatory activities of durian (Durio zibethinus Murr.) pulp, seed and peel flour | |
US20210069280A1 (en) | Nutritional supplements affecting gut-brain-axis balance and mental wellness | |
Kaur et al. | Development of composite meat chocolate fortified with calcium and plant extracts | |
Arnold et al. | Innovative application of chicken eggshell calcium to improve the functional value of gingerbread | |
CN104605373A (zh) | 营养补充剂及其制备的压片糖果 | |
Antarkar et al. | Physico-chemical and nutritional evaluation of cookies with different levels of Rosehip and Hibiscus powder substitution | |
Dehbi et al. | Bioactive constituents, antioxidant activity and in vitro cancer cell cytotoxicity of Moroccan prickly pear (Opuntia ficus indica L.) juices | |
Jrad et al. | Fortification of goat yogurt with roasted date seeds (Phoenix dactylifera L.) powder: Impact on nutritional, technological, phenolic profile, antioxidant and sensory properties | |
Ibraimova et al. | Development of recipe composition of bread with the inclusion of juniper using mathematical modeling and assessment of its quality | |
Sharma et al. | Withania somnifera fruit extract is effective in controlling microbial growth and lipid oxidation and improves the functional value of cheese | |
Jridi et al. | Vine (Vitis vinifera L.) leaves as a functional ingredient in pistachio calisson formulations | |
Sturza et al. | Use of sea buckthorn fruits in the pastry manufacturing | |
KALIČANIN et al. | A study on mineral composition of Aronia melanocarpa as a functional food with potential therapeutic properties. | |
Kaplan et al. | An optimization study for the production of Origanum onites tincture by response surface methodology: Effect of solid/liquid ratio, ethanol concentration and storage period | |
Mutlu | Bee pollen usage as carrier material in the drying of honey and some properties of honey-bee pollen powders | |
Siyukhov et al. | Scientific justification and development of critical solution for the production of phytocomposite mixtures to enrich nonalcoholic beverages | |
Mazzoni et al. | Evaluation of strawberry (Fragaria× ananassa Duch.) Alba sensorial and nutritional quality, and its in vitro effects against human breast cancer cells viability | |
CN105533742A (zh) | 一种青海三刺多糖组合物及泡腾片剂和用途 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Nutritional supplement and pressed candies prepared from nutritional supplement Effective date of registration: 20191231 Granted publication date: 20170118 Pledgee: Bank of Weifang Limited by Share Ltd. Qingdao branch Pledgor: QINGDAO SAMUELS INDUSTRIAL & COMMERCIAL Co.,Ltd. Registration number: Y2019370010057 |
|
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170118 |
|
CF01 | Termination of patent right due to non-payment of annual fee |