CN104604928A - Compound medicine for synergy for killing termites - Google Patents
Compound medicine for synergy for killing termites Download PDFInfo
- Publication number
- CN104604928A CN104604928A CN201510065107.9A CN201510065107A CN104604928A CN 104604928 A CN104604928 A CN 104604928A CN 201510065107 A CN201510065107 A CN 201510065107A CN 104604928 A CN104604928 A CN 104604928A
- Authority
- CN
- China
- Prior art keywords
- compound medicine
- termite
- medicine
- synergy
- sulfluramid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Agricultural Chemicals And Associated Chemicals (AREA)
- Catching Or Destruction (AREA)
Abstract
The invention discloses a compound medicine for synergy for killing termites, belonging to a compound pesticide. The compound medicine is compounded by sulfluramid and thiamethoxam. Compared with single agent, the compound medicine has a synergy effect on termites, the prevention effect can be improved, the co-toxicity coefficient of the compound medicine is more than 113, the maximum value can be 227; the defects that thiamethoxam over-rapidly kills termites can be overcome, the toxicity of the medicine to the termites is favorably transferred, and the whole termites crow is more effectively killed; compared with the single agent, the combination of two single agents can lower the application cost; in addition, the thiamethoxam and sulfluramid are low-toxicity pesticide, so that the use is safe and the compound meets the environment-friendly requirement.
Description
Technical field
The present invention relates to a kind of composite insecticide, in particular, the present invention relates generally to a kind of going out for termite and controls the compound medicine of synergy.
Background technology
Termite is one of global five major pests, very wide in the distribution of China.Termite damage has disguise, and its harm almost relates to each department of national economy, main harm building construction, reservoir dam, farm-forestry crop, cable means of transportation etc.China is every year because of economic loss about 20 ~ 2,500,000,000 yuan that termite damage causes.The rationally composite of agricultural chemicals can not only overcome and delay pesticide resistance, and can improve the effects such as drug effect, minimizing times for spraying, reduction cost accounting, and therefore, agriculture chemical compounding, as a kind of new technique in using agriculture chemical, is more and more subject to people's attention.But in termiticide is composite, the research of compound medicine is less, compound medicine cultivar registration quantity is also little.According to statistics, there is kind more than 40 in China by the termiticides product of Ministry of Agriculture's agriculture chemical registration, but compound drug only has 3 kinds, and proportion is less than 10%, so the research and development of termite control compound medicine has larger market prospects.In addition, according to statistics, up to now, China has 4 kinds by the pulvis of registration, bait formulation has 3 kinds.So, no matter be built agent or single dose, alternative termite is gone out and controls that pharmacy variety quantity is few, selectivity is low, and some medicament (built agent or single dose) makes us querying to the control of termite population or insect killing effect, can not meet termite and go out and control the needs of real work.
Summary of the invention
An object of the present invention is for above-mentioned deficiency, provides a kind of going out for termite to control the compound medicine of synergy, to expect to solve in prior art composite on termite control or Population Control and single dose kind is less, to technical problems such as the killing effect of termite are not good.
For solving above-mentioned technical problem, the present invention by the following technical solutions:
A kind of going out for termite provided by the present invention controls the compound medicine of synergy, and described compound medicine is composited by sulfluramid and Diacloden.
As preferably, further technical scheme is: in described compound medicine, the weight fraction ratio of sulfluramid and Diacloden is 1 ~ 40:1 ~ 40.
Further technical scheme is: described compound medicine is any one in the middle of pulvis, bait formulation or jelly.
Compared with prior art, beneficial effect of the present invention is mainly:
1, compared with single dose, combination drug of the present invention has synergistic effect to termite, can improve preventive effect, and the co-toxicity coefficient of built agent is all greater than 113, and the highest reaches 227;
2, Diacloden can be overcome and too fast shortcoming is knocked down to termite, be beneficial to the virulence transmission of termite to medicament, more effectively kill whole ant group;
3, compared with single dose, two kinds of single dose combinations can reduce application cost;
4, Diacloden, sulfluramid are low-toxin farm chemicals, use safety, meet environmental requirement.
Embodiment
Below in conjunction with subordinate list, the present invention is further elaborated.
Understand the present invention better for ease of those skilled in the art, be described in further details by embodiment.The compound medicine preparation that the following embodiment of the present invention adopts is the corresponding processing method based on the existing formulations of pesticide, by sulfluramid and Diacloden, auxiliary agent conventional method, makes pulvis, bait formulation or jelly by the proportioning in embodiment.Agents useful for same is market and buys, and the main body that neither invent, repeats no more herein.In these embodiments, apart from outside specified otherwise, all proportionings are weight ratio, specifically in table 1.
Table 1: termite is gone out and controls the compound medicine embodiment of synergy
| Sequence number | Sulfluramid: Diacloden (weight ratio) |
| Embodiment 1 | 1:1 |
| Embodiment 2 | 5:1 |
| Embodiment 3 | 10:1 |
| Embodiment 4 | 20:1 |
| Embodiment 5 | 40:1 |
| Embodiment 6 | 1:5 |
| Embodiment 7 | 1:10 |
| Embodiment 8 | 1:20 |
| Embodiment 9 | 1:40 |
Based on the above embodiments, inventor is to this has been determination of activity, and concrete is reported as follows:
One, object
Adopt the method for indoor bioassay, the built agent measuring different proportion to the co-toxicity coefficient of termite and nitrate enhancement, to determine that built agent synergistic effect is strong and weak.
Two, assay method
1, reagent agent
Sulfluramid (98%) is provided by national agricultural chemicals Product Quality Verification Centers, and Diacloden (98.5%) is provided by Shanghai Pesticide Research Institute.
2, for examination insect
Formosanes Coptotermes formosanus picks up from Xuancheng Profile, anhui Province, raises with pine block, for test after indoor separation raised at least 1 week.
3, single dose is to the toxicity test of termite
Respectively sulfluramid and the former medicine of Diacloden are made into the mother liquor of about 1000ppm with acetone.With acetone, the mother liquor of two kinds of medicines is diluted to series concentration.Pipette liquid 1ml with pipette, drip on filter paper (Ф 90mm), form even medicine film, after naturally drying, put into clean culture dish (Ф 90mm).Drip 1ml deionized water, drop into 30 formosanes worker ants, continuous contact.3 repetitions, if blank, observe and the record poisoning symptom of termite and death toll every day, test 28 ± 1 DEG C, carry out under dark condition, and note keeping the moistening of filter paper.
4, compound medicine is to the toxicity test of termite
The maximum concentration being used in sulfluramid and Diacloden in single dose toxicity test is respectively mixed into the proportioning (specifically in table 1) in embodiment by a certain percentage, is then down diluted to 4-5 concentration by geometric ratio principle.Pipette 1ml liquid with pipette and evenly drip on filter paper (Φ 9cm), form medicine film, after naturally drying, put into clean culture dish (Φ 90mm).Drip 1ml deionized water, drop into 30 formosanes worker ants, continuous contact.3 repetitions, if blank, observe and record poisoning symptom and the death toll of termite every day, and obtain the LC of various built agent
50value and co-toxicity coefficient, test 28 ± 1 DEG C, carry out under dark condition, and note keeping the moistening of filter paper.
Three, result and discussion
1, sulfluramid and Diacloden are to the virulence of termite
The termite mortality borer population of every day is added up, calculate the cumulative mortality of termite after different number of days, with the logarithm value of drug concentration for independent variable X, be dependent variable Y the probit value of the average cumulative lethality of (96h) after 4 days, calculate the virulence regression equation of this medicine with EXCELL, obtain the LC of various medicine
50value, the results are shown in Table 2.The LC of sulfluramid
50value for 26.199mg/L, Diacloden be 4.832mg/L, Diacloden is to the height of the virulence of termite than sulfluramid, and after medicine embrane method process, after 96h, the former is 5.4 times of the latter to the virulence of termite, specifically see table 2.
Table 2: to the virulence of termite after medicine single dose 96h
| Medicament | Virulence regression equation | LC 50Value (mg/L) | 95% confidence limit | Correlation coefficient |
| Sulfluramid | Y＝2.031+2.093X | 26.199 | 22.292-30.790 | 0.99 |
| Diacloden | Y＝4.141+1.256X | 4.832 | 2.094-11.151 | 0.95 |
2, built agent is to the synergistic effect of termite
Built agent is added up to the dead borer population every day of termite, calculate the cumulative mortality of termite after different number of days, with the logarithm value of drug concentration for independent variable X, be dependent variable Y the probit value of the average cumulative lethality of (96h) after 4 days, calculate the virulence regression equation of this medicine with EXCELL, obtain the LC of the built agent of sulfluramid and Diacloden different proportion
50value.Obtain co-toxicity coefficient and the nitrate enhancement of built agent by the abundant method of Sun Yun, specifically see following formula:
In the toxicity index × mixture of the theoretical toxicity index=A medicine of mixture the percentage composition+B medicine of A medicine toxicity index × mixture in the percentage composition of B medicine
Table 3: the virulence to formosanes after the complex preparation 96h of different proportion
Different built agent is to the LC of termite
50the co-toxicity coefficient of value and built agent, nitrate enhancement are in table 3.Sulfluramid and Diacloden effective ingredient are all greater than 100 than the co-toxicity coefficient of the built agent being 1 ~ 40:1 ~ 40, nitrate enhancement is greater than 0, show that sulfluramid and Thiamethoxam compound agent all have synergistic effect to termite, wherein sulfluramid: Diacloden be 1:5,10:1 and 40:1 ratio composite time, their co-toxicity coefficient is respectively 227.30,205.41,168.80, nitrate enhancement is 1.273,1.05,0.69, has significant synergistic effect.
And than that described above, also it should be noted that spoken of in this manual " embodiment ", " another embodiment ", " embodiment " etc., refer to the specific features, structure or the feature that describe in conjunction with this embodiment and be included at least one embodiment of the application's generality description.Multiple place occurs that statement of the same race is not necessarily refer to same embodiment in the description.Furthermore, when describing specific features, structure or a feature in conjunction with any embodiment, what advocate is also fall within the scope of the invention to realize this feature, structure or feature in conjunction with other embodiments.
Although with reference to multiple explanatory embodiment of the present invention, invention has been described here, but, should be appreciated that, those skilled in the art can design a lot of other amendment and embodiment, these amendments and embodiment will drop within spirit disclosed in the present application and spirit.More particularly, in the scope of and claim open in the application, multiple modification and improvement can be carried out to the building block of subject combination layout and/or layout.Except the modification of carrying out building block and/or layout is with except improvement, to those skilled in the art, other purposes also will be obvious.
Claims (4)
1. go out for termite and control a compound medicine for synergy, it is characterized in that: described compound medicine is composited by sulfluramid and Diacloden.
2. according to claim 1 going out for termite controls the compound medicine of synergy, it is characterized in that: in described compound medicine, the weight fraction ratio of sulfluramid and Diacloden is 1 ~ 40: 1 ~ 40.
3. according to claim 1 going out for termite controls the compound medicine of synergy, it is characterized in that: described compound medicine is any one in the middle of pulvis, bait formulation or jelly.
4. according to claim 1 going out for termite controls the compound medicine of synergy, it is characterized in that: in described compound medicine, the sulfluramid of effective dose and the active component of Diacloden account for 0.05% ~ 30% of compound medicine gross weight.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510065107.9A CN104604928A (en) | 2015-02-06 | 2015-02-06 | Compound medicine for synergy for killing termites |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510065107.9A CN104604928A (en) | 2015-02-06 | 2015-02-06 | Compound medicine for synergy for killing termites |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104604928A true CN104604928A (en) | 2015-05-13 |
Family
ID=53139801
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510065107.9A Pending CN104604928A (en) | 2015-02-06 | 2015-02-06 | Compound medicine for synergy for killing termites |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN104604928A (en) |
Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1505931A (en) * | 2002-12-09 | 2004-06-23 | 毛伟光 | Sulfuramid prepn for preventing and controlling termite and its usage |
| CN1933732A (en) * | 2004-03-25 | 2007-03-21 | Fmc有限公司 | Liquid termiticide compositions of pyrethroids and a neonicitinoids |
| CN101861876A (en) * | 2010-06-02 | 2010-10-20 | 柳州市白蚁防治所 | Soil termite trapping medicine and soil termite trapping method by using the same |
| CN102948419A (en) * | 2012-11-06 | 2013-03-06 | 南京市白蚁防治研究所 | Termite killing drug compound combination |
| WO2014079766A1 (en) * | 2012-11-22 | 2014-05-30 | Basf Se | Pesticidal mixtures |
-
2015
- 2015-02-06 CN CN201510065107.9A patent/CN104604928A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1505931A (en) * | 2002-12-09 | 2004-06-23 | 毛伟光 | Sulfuramid prepn for preventing and controlling termite and its usage |
| CN1933732A (en) * | 2004-03-25 | 2007-03-21 | Fmc有限公司 | Liquid termiticide compositions of pyrethroids and a neonicitinoids |
| CN101861876A (en) * | 2010-06-02 | 2010-10-20 | 柳州市白蚁防治所 | Soil termite trapping medicine and soil termite trapping method by using the same |
| CN102948419A (en) * | 2012-11-06 | 2013-03-06 | 南京市白蚁防治研究所 | Termite killing drug compound combination |
| WO2014079766A1 (en) * | 2012-11-22 | 2014-05-30 | Basf Se | Pesticidal mixtures |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN104322558A (en) | Sterilization composition and applications thereof | |
| CN105724399A (en) | Sterilization composition containing berberine and azoxystrobin | |
| CN102860306B (en) | Insecticide for killing termites and preparation method of insecticide | |
| CN103141503A (en) | Dinotefuran/Spirotetramat compound insecticidal composition | |
| CN104255772B (en) | A kind of sanitary insect pest Pesticidal combination and application thereof containing Diacloden and Nylar | |
| CN102388873A (en) | Downy mildew fungicide for promoting crop growth and application thereof | |
| CN102342284B (en) | Sterilization disease-resistant composition and suspension seed coating agent thereof | |
| CN103858912B (en) | A kind of composition pesticide of control termites | |
| CN103875703B (en) | A kind of agricultural chemicals paste preventing and treating longicorn | |
| CN103070186B (en) | Insecticidal composition containing thiamethoxam and application of insecticidal composition | |
| CN105284838A (en) | Pesticide composition capable of preventing and treating white ants | |
| CN108208015A (en) | A kind of agricultural chemicals suspension agent and its preparation method and application | |
| CN102948419B (en) | Termite killing drug compound combination | |
| CN104604928A (en) | Compound medicine for synergy for killing termites | |
| CN104642375B (en) | A kind of health compounded pesticides and application thereof containing right anti-propargyl chloride chrysanthemum ester | |
| CN106797941A (en) | A kind of bactericidal composition with cooperative effect and application thereof | |
| CN106879609A (en) | A kind of Pesticidal combination containing doractin and Nylar | |
| CN103155938B (en) | Clothianidin/Diafenthiuron compound insecticidal composition | |
| CN105165881B (en) | Pesticide composition containing clothianidin and sulfluramid for controlling termites | |
| CN111184034A (en) | Pesticide composition containing pyridine quinazoline and eucalyptol | |
| CN115281199B (en) | Insecticidal composition for preventing and controlling spinach plutella xylostella | |
| CN112772671A (en) | Dinotefuran-containing compound insecticidal composition and application thereof | |
| CN107711884A (en) | It is a kind of to be gone out the compounded combination controlled and its application for termite | |
| CN115281205B (en) | Insecticidal composition for preventing and controlling peach fruit borer | |
| CN107410343A (en) | A kind of Pesticidal composition containing AVM and pyrazosulfuron |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150513 |