CN104603600B - 用于散射介质中改进的扩散发光成像或者断层照相的系统和方法 - Google Patents

用于散射介质中改进的扩散发光成像或者断层照相的系统和方法 Download PDF

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CN104603600B
CN104603600B CN201380035375.5A CN201380035375A CN104603600B CN 104603600 B CN104603600 B CN 104603600B CN 201380035375 A CN201380035375 A CN 201380035375A CN 104603600 B CN104603600 B CN 104603600B
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excitation
luminescent
light
luminescence
imaging
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CN104603600A (zh
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斯蒂芬·安德森·恩格斯
C.徐
H.刘
庞图斯·斯文马克
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Lumito AB
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0071Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by measuring fluorescence emission
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47Scattering, i.e. diffuse reflection
    • G01N21/4795Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/645Specially adapted constructive features of fluorimeters
    • G01N21/6456Spatial resolved fluorescence measurements; Imaging
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/62Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light
    • G01N21/63Systems in which the material investigated is excited whereby it emits light or causes a change in wavelength of the incident light optically excited
    • G01N21/64Fluorescence; Phosphorescence
    • G01N21/6428Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes"
    • G01N2021/6439Measuring fluorescence of fluorescent products of reactions or of fluorochrome labelled reactive substances, e.g. measuring quenching effects, using measuring "optrodes" with indicators, stains, dyes, tags, labels, marks

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Radiology & Medical Imaging (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Magnetic Resonance Imaging Apparatus (AREA)
CN201380035375.5A 2012-07-01 2013-07-01 用于散射介质中改进的扩散发光成像或者断层照相的系统和方法 Active CN104603600B (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201261666899P 2012-07-01 2012-07-01
US61/666,899 2012-07-01
US201361771131P 2013-03-01 2013-03-01
US61/771,131 2013-03-01
PCT/EP2013/063878 WO2014006012A1 (en) 2012-07-01 2013-07-01 A system and method for improved diffuse luminescent imaging or tomography in scattering media

Publications (2)

Publication Number Publication Date
CN104603600A CN104603600A (zh) 2015-05-06
CN104603600B true CN104603600B (zh) 2017-09-01

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US (1) US10143380B2 (enExample)
EP (1) EP2867653B1 (enExample)
JP (1) JP6443934B2 (enExample)
KR (1) KR102100614B1 (enExample)
CN (1) CN104603600B (enExample)
AU (1) AU2013285996B2 (enExample)
CA (1) CA2879769C (enExample)
IL (1) IL236424A0 (enExample)
WO (1) WO2014006012A1 (enExample)
ZA (1) ZA201409381B (enExample)

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BR112014010848B1 (pt) * 2011-11-08 2022-12-27 Koninklijke Philips N.V Sistema e método para anotação interativa de uma imagem, estação de trabalho, aparelho gerador de imagens
US10387698B2 (en) * 2015-02-19 2019-08-20 South Dakota Board Of Regents Reader apparatus for upconverting nanoparticle ink printed images
JP6966942B2 (ja) * 2015-06-05 2021-11-17 アップル インコーポレイテッドApple Inc. 表示パネル用の発光制御装置及び方法
KR101700287B1 (ko) * 2015-06-17 2017-01-31 전호상 단층촬영에서의 양자검출효율 측정용 팬텀 및 이를 이용한 양자검출효율 측정방법
US10603001B2 (en) 2015-07-01 2020-03-31 General Electric Company Energy modulated luminescence tomography
US12019074B2 (en) 2017-06-08 2024-06-25 Lumito Ab Method of analysing a sample for at least one analyte
KR102253350B1 (ko) * 2017-12-20 2021-05-18 주식회사 고영테크놀러지 옵티컬 트래킹 시스템 및 옵티컬 트래킹 방법
KR102166372B1 (ko) 2017-12-20 2020-10-15 주식회사 고영테크놀러지 옵티컬 트래킹 시스템 및 옵티컬 트래킹 방법
US11872068B2 (en) 2018-11-05 2024-01-16 Socpra Sciences Et Génie S.E.C. Pulsed X-ray imaging
NL2022223B1 (en) * 2018-12-17 2020-07-03 Lumicks Tech B V Microscopy method and system
JP7240995B2 (ja) * 2019-09-17 2023-03-16 株式会社アドバンテスト ファントムおよび蛍光検出装置
CN114923884A (zh) * 2022-04-06 2022-08-19 清华大学 测量上转换材料中镧系元素离子本征弛豫速率参数的方法
CN116285575B (zh) * 2023-03-15 2024-03-29 北京机电工程总体设计部 一种焰流烧蚀实验背温微区成像涂料、制备及使用方法
EP4439133A1 (en) 2023-03-27 2024-10-02 Lumito AB A microscope for upconverting nanoparticles
CN118349824B (zh) * 2024-03-29 2024-12-24 昆明理工大学 一种星载全波形激光雷达回波的最优脉宽高斯分解方法

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CN1582394A (zh) * 2001-09-06 2005-02-16 基因描绘系统有限公司 分子的快速灵敏检测
WO2010128090A1 (en) * 2009-05-05 2010-11-11 Stefan Andersson-Engels A system, method, and luminescent marker for improved diffuse luminescent imaging or tomography in scattering media

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JP2001272343A (ja) * 2000-03-23 2001-10-05 Olympus Optical Co Ltd 二重共鳴吸収顕微鏡

Patent Citations (2)

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CN1582394A (zh) * 2001-09-06 2005-02-16 基因描绘系统有限公司 分子的快速灵敏检测
WO2010128090A1 (en) * 2009-05-05 2010-11-11 Stefan Andersson-Engels A system, method, and luminescent marker for improved diffuse luminescent imaging or tomography in scattering media

Non-Patent Citations (4)

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High-Resolution Fluorescence Diffuse Optical Tomography Developed with Nonlinear Upconverting Nanoparticles;CAN T. XU 等;《ACS NANO》;20120626;第6卷(第6期);4788-4795 *
Multibeam fluorescence diffuse optical tomography using upconverting nanoparticles;LIU H 等;《OPTICS LETTERS,THE OPTICAL SOCIETY》;20100301;第35卷(第5期);718-720 *
Nanoparticles for highly efficient multiphoton fluorescence bioimaging;L Martinez Maestro 等;《Optics Express》;20101108;23544-23553 *
Toward the Use of Two-Color Emission Control in Upconverting NaYF4:Er3+, Yb3+ Nanoparticles for Biomedical Imaging;Christian F. Gainer 等;《Proc SPIE Int Soc Opt Eng》;20120201;1-8 *

Also Published As

Publication number Publication date
CN104603600A (zh) 2015-05-06
AU2013285996A1 (en) 2015-02-05
CA2879769A1 (en) 2014-01-09
WO2014006012A1 (en) 2014-01-09
JP6443934B2 (ja) 2018-12-26
US20150196201A1 (en) 2015-07-16
AU2013285996B2 (en) 2017-01-19
ZA201409381B (en) 2017-08-30
KR102100614B1 (ko) 2020-04-14
KR20150043299A (ko) 2015-04-22
JP2015525587A (ja) 2015-09-07
CA2879769C (en) 2022-06-21
US10143380B2 (en) 2018-12-04
EP2867653B1 (en) 2020-09-16
IL236424A0 (en) 2015-02-26
EP2867653A1 (en) 2015-05-06

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