CN104587353A - Medicament for treating scar - Google Patents

Medicament for treating scar Download PDF

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Publication number
CN104587353A
CN104587353A CN201510087862.7A CN201510087862A CN104587353A CN 104587353 A CN104587353 A CN 104587353A CN 201510087862 A CN201510087862 A CN 201510087862A CN 104587353 A CN104587353 A CN 104587353A
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radix
semen
rhizoma
persicae
cicatrix
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CN201510087862.7A
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CN104587353B (en
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刘相明
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Weifang Medical University
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Abstract

The invention provides a medicament for treating scar. The medicament is characterized by comprising the following components by weight: 6-12 g of safflower, 6-12 g of madder, 3-9 g of caltrop, 5-15 parts of fructus gardeniae, 2-8 g of allium fistulosum, 3-9 g of rosemary, 10-20 g of oenothera biennis, 5-15 g of ligusticum wallichii, 2-8 g of hawthorn, 3-9 g of flores aurantii, 2-8 g of sweet almond oil and the like. The medicament provided by the invention has internal and external treatment functions, can effectively eliminate skin scar diseases caused by cuts, burns, acne and the like, has the efficacies of resolving hard lump, promoting blood circulation and removing stasis, and removing slough and promoting growth of tissue regeneration, can restrain itching symptoms caused by skin scar and dilute stain formed by the scar healing process and other symptoms, and has the advantages of obvious treatment effect, few side effects and low possibility in recovery.

Description

A kind of medicine for the treatment of cicatrix
Technical field
The present invention relates to the field of Chinese medicines, specifically, relate to a kind of medicine for the treatment of cicatrix.
Background technology
Cicatrix is the mode of appearance of normal skin tissue caused after various wound and the general designation of tissue pathologies change, and it is product inevitable in human body processes of wound repair.Cicatrix growth exceedes certain limit, various complication will occur, the destruction of such as profile and functional activity obstacle etc., the cicatrix brought the painful and psychic pain of the huge human body to patient, especially burn, scald, leave over after severe trauma.
At present, treat cicatrix on the market mainly through operation and Drug therapy, but operative treatment has a big risk, and easily recurs, and Drug therapy easily has side effects, weak curative effect.
Summary of the invention
The technical problem to be solved in the present invention overcomes above-mentioned defect, the medicine for the treatment of cicatrix provide a kind of good effect, few side effects, not easily recurring.
For solving the problem, the technical solution adopted in the present invention is:
Treat a medicine for cicatrix, it is characterized in that, described medicine comprises following component:
Flos Carthami 6-12g, Radix Rubiae 6-12g, Fructus Tribuli 3-9g, SHANZHIZI 5-15g, Bulbus Allii Fistulosi 2-8g, Herba Rosmarini Officinalis 3-9g, Radix Oenotherae erythrosepalae 10-20g, Rhizoma Chuanxiong 5-15g, Fructus Crataegi 2-8g, orange blossom 3-9g, Semen pruni armeniacae oil 2-8g, Rhizoma Alpiniae Officinarum 10-20g, Radix Angelicae Dahuricae 6-12g, Concha Ostreae (calcined) 3-9g, Radix Saposhnikoviae 5-15g, Rhizoma Atractylodis Macrocephalae 6-12g, Folium Hibisci Mutabilis 5-15g, Folium chrysanthemi 3-9g, Flos persicae 2-8g, Semen Persicae 2-8g, raw Semen Phaseoli 5-15g.
Improve as one, described medicine comprises following component:
Flos Carthami 9g, Radix Rubiae 9g, Fructus Tribuli 6g, SHANZHIZI 10g, Bulbus Allii Fistulosi 5g, Herba Rosmarini Officinalis 6g, Radix Oenotherae erythrosepalae 15g, Rhizoma Chuanxiong 10g, Fructus Crataegi 5g, orange blossom 6g, Semen pruni armeniacae oil 5g, Rhizoma Alpiniae Officinarum 15g, Radix Angelicae Dahuricae 9g, Concha Ostreae (calcined) 6g, Radix Saposhnikoviae 10g, Rhizoma Atractylodis Macrocephalae 9g, Folium Hibisci Mutabilis 10g, Folium chrysanthemi 6g, Flos persicae 5g, Semen Persicae 5g, raw Semen Phaseoli 10g.
Optionally, described medicine comprises following component:
Flos Carthami 6g, Radix Rubiae 6g, Fructus Tribuli 3g, SHANZHIZI 5g, Bulbus Allii Fistulosi 2g, Herba Rosmarini Officinalis 3g, Radix Oenotherae erythrosepalae 10g, Rhizoma Chuanxiong 5g, Fructus Crataegi 2g, orange blossom 3g, Semen pruni armeniacae oil 2g, Rhizoma Alpiniae Officinarum 10g, Radix Angelicae Dahuricae 6g, Concha Ostreae (calcined) 3g, Radix Saposhnikoviae 5g, Rhizoma Atractylodis Macrocephalae 6g, Folium Hibisci Mutabilis 5g, Folium chrysanthemi 3g, Flos persicae 2g, Semen Persicae 2g, raw Semen Phaseoli 5g.
Optionally, described medicine comprises following component:
Flos Carthami 12g, Radix Rubiae 12g, Fructus Tribuli 9g, SHANZHIZI 15g, Bulbus Allii Fistulosi 8g, Herba Rosmarini Officinalis 9g, Radix Oenotherae erythrosepalae 20g, Rhizoma Chuanxiong 15g, Fructus Crataegi 8g, orange blossom 9g, Semen pruni armeniacae oil 8g, Rhizoma Alpiniae Officinarum 20g, Radix Angelicae Dahuricae 12g, Concha Ostreae (calcined) 9g, Radix Saposhnikoviae 15g, Rhizoma Atractylodis Macrocephalae 12g, Folium Hibisci Mutabilis 15g, Folium chrysanthemi 9g, Flos persicae 8g, Semen Persicae 8g, raw Semen Phaseoli 15g.
Wherein:
Flos Carthami has the effect such as promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, traumatic injury.
Radix Rubiae has effect of cooling blood for hemostasis, blood circulation promoting and blood stasis dispelling.Cure mainly the disease such as heat in blood spitting of blood, postpartum stagnation stomachache, traumatic injury, rheumatic arthralgia.
Fructus Tribuli has effect of suppressing the hyperactive liver resolving depression, dispelling pathogenic wind for improving eyesight.For diseases such as dizziness due to hyperactivity of liver-YANG headache, hypochondriac pain due to stagnation of liverQI, headache due to pathogenic wind-heat, conjunctival congestion and swelling pain, skin pruritus.
SHANZHIZI has heat clearing away, pathogenic fire purging, effect of removing heat from blood.Control calentura restlessness of asrhenia type and insomnia, jaundice, gonorrhea, quench one's thirst, conjunctival congestion, pharyngalgia, spit blood, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprains and swells and ache.
Bulbus Allii Fistulosi has delivers cold expelling, and activate yang inducing resuscitation, effect of removing toxic substances parasite killing.
Herba Rosmarini Officinalis external can treat wound and arthritis.Also there is strong heart, promote metabolism, promote the effects such as the blood circulation of peripheral vessel.
Radix Oenotherae erythrosepalae has the effect such as wind-damp dispelling, bone and muscle strengthening.Main anemofrigid-damp arthralgia, soreness of bones and muscles, promoting blood circulation to remove obstruction in the collateral, endogenous wind stopping suppressing the hyperactive liver, detumescence sore.Main obstruction of qi in the chest and cardialgia, apoplectic hemiplegia, stirring-up of pathogenic wind in the interior resulting from deficiency, children's many dynamic, wind dampness rheumatic anesthesia pain, stomachache are had loose bowels, dysmenorrhea, oral-anal-genital ulcer syndrome, skin infection, eczema.
The pungent loose temperature of Rhizoma Chuanxiong is led to.The pain relieving of energy dispelling wind and removing obstruction in the collateral, again can dispelling the wind and dampness pathogens arthralgia pain.
Fructus Crataegi can promoting digestion and removing stagnation, spleen invigorating, blood circulation promoting and blood stasis dispelling, blood pressure lowering.
Orange blossom has the effect of whitening, moisturizing, improvement sensitivity, promotes cell regeneration, eliminates cicatrix, striae gravidarum, varicosis.
Semen pruni armeniacae oil can soft skin, crease-resistant, whitening, healing cicatrix, promote tissue regeneration, have good moistening and the effect of soft skin, have good opsonic action to pimples skin, also can itch as treatment, formula that is red and swollen, dry skin uses.
The effects such as Rhizoma Alpiniae Officinarum has dispersing cold for relieving pain, warming middle-JIAO to arrest vomiting.
The Radix Angelicae Dahuricae gets rid of illness the functions such as dehumidifying, evacuation of pus granulation promoting, promoting blood circulation and stopping pain.Cure mainly anemofrigid cold, headache, rhinitis, toothache.The diseases such as leucorrhea with red and white discharge, pain furuncle and phyma poison.
Concha Ostreae (calcined) has convergence astringent or styptic treatment for spontaneous sweating, relieving gastric hyperacidity to alleviate stomachache, tranquillization with heavy prescription, the effects such as hard masses softening and resolving.With Radix Saposhnikoviae, the Rhizoma Atractylodis Macrocephalae is compatible stopping perspiration with astringents, effect of dispelling wind to relieve the exterior syndrome.
Radix Saposhnikoviae has expelling pathogenic wind from the body surface, removing dampness to relieve pain, effect of relieving convulsion.
The Rhizoma Atractylodis Macrocephalae has invigorating the spleen and benefiting QI, dampness diuretic, hidroschesis, antiabortive effect.Have loose bowels for insufficiency of the spleen lack of appetite, abdominal distention, phlegm retention vertigo and palpitation, edema, spontaneous perspiration, frequent fetal movement.
Folium Hibisci Mutabilis has the effect such as Qingfei Liangxue, detumescence and apocenosis.For cough due to lung-heat, hypertrophic rhinitis, lymphadenitis, appendicitis, carbuncle furuncle abscess, acute otitis media, burn, scald.
Folium chrysanthemi takes wind and heat dispersing removing pathogenic heat from blood and toxic substance from the body orally; Externally applied toxicity removing detumescent.Can be cured cold headache, wind heat acute conjunctivitis, and eyes is dim-sighted, parotitis, gets injured by a fall syncope; Outer treatment skin ulcer, skin sore subcutaneous ulcer toxic swelling.
Flos persicae has diuretic, invigorates blood circulation, the effects such as relieving constipation.Harness the river swollen, beriberi, phlegm retention, stagnant, difficulty in urination and defecation, amenorrhea.
Semen Persicae has blood circulation promoting and blood stasis dispelling, loosening bowel to relieve constipation, the effects such as relieving cough and asthma.For amenorrhea dysmenorrhea, abdominal mass abdominal mass mass in the abdomen, lung abscess acute appendicitis, injury from falling down, dryness of the intestine constipation, cough and asthma.
Raw Semen Phaseoli can be inducing diuresis and reducing edema, heat clearing away jaundice eliminating, removing toxic substances and promoting pus discharge.
Medicine internal and external application of the present invention, effectively can eliminate the cicatrix of skin disease that knife injury, burn and acne etc. cause, there is hard masses softening and resolving, blood circulation promoting and blood stasis dispelling, putrefaction-removing granulation-promoting effect, the pain symptom of itching caused by cicatrix of skin can be suppressed, the symptoms such as the mottle formed in desalination scar healing process, have evident in efficacy, few side effects, the advantage not easily recurred.
Detailed description of the invention
Embodiment 1: a kind of medicine for the treatment of cicatrix, described medicine comprises following component:
Flos Carthami 9g, Radix Rubiae 9g, Fructus Tribuli 6g, SHANZHIZI 10g, Bulbus Allii Fistulosi 5g, Herba Rosmarini Officinalis 6g, Radix Oenotherae erythrosepalae 15g, Rhizoma Chuanxiong 10g, Fructus Crataegi 5g, orange blossom 6g, Semen pruni armeniacae oil 5g, Rhizoma Alpiniae Officinarum 15g, Radix Angelicae Dahuricae 9g, Concha Ostreae (calcined) 6g, Radix Saposhnikoviae 10g, Rhizoma Atractylodis Macrocephalae 9g, Folium Hibisci Mutabilis 10g, Folium chrysanthemi 6g, Flos persicae 5g, Semen Persicae 5g, raw Semen Phaseoli 10g.
Embodiment 2: a kind of medicine for the treatment of cicatrix, described medicine comprises following component:
Flos Carthami 6g, Radix Rubiae 6g, Fructus Tribuli 3g, SHANZHIZI 5g, Bulbus Allii Fistulosi 2g, Herba Rosmarini Officinalis 3g, Radix Oenotherae erythrosepalae 10g, Rhizoma Chuanxiong 5g, Fructus Crataegi 2g, orange blossom 3g, Semen pruni armeniacae oil 2g, Rhizoma Alpiniae Officinarum 10g, Radix Angelicae Dahuricae 6g, Concha Ostreae (calcined) 3g, Radix Saposhnikoviae 5g, Rhizoma Atractylodis Macrocephalae 6g, Folium Hibisci Mutabilis 5g, Folium chrysanthemi 3g, Flos persicae 2g, Semen Persicae 2g, raw Semen Phaseoli 5g.
Embodiment 3: a kind of medicine for the treatment of cicatrix, described medicine comprises following component:
Flos Carthami 12g, Radix Rubiae 12g, Fructus Tribuli 9g, SHANZHIZI 15g, Bulbus Allii Fistulosi 8g, Herba Rosmarini Officinalis 9g, Radix Oenotherae erythrosepalae 20g, Rhizoma Chuanxiong 15g, Fructus Crataegi 8g, orange blossom 9g, Semen pruni armeniacae oil 8g, Rhizoma Alpiniae Officinarum 20g, Radix Angelicae Dahuricae 12g, Concha Ostreae (calcined) 9g, Radix Saposhnikoviae 15g, Rhizoma Atractylodis Macrocephalae 12g, Folium Hibisci Mutabilis 15g, Folium chrysanthemi 9g, Flos persicae 8g, Semen Persicae 8g, raw Semen Phaseoli 15g.
In addition, in above-described embodiment, a kind of manufacture method for the treatment of the medicine of cicatrix is: raw Semen Phaseoli, Semen Persicae pulverizing, Concha Ostreae (calcined) flour, Flos Carthami, Radix Rubiae, Fructus Tribuli, SHANZHIZI, Herba Alii fistulosi is white, Herba Rosmarini Officinalis, Radix Oenotherae erythrosepalae, Rhizoma Chuanxiong, Fructus Crataegi, orange blossom, Rhizoma Alpiniae Officinarum, the Radix Angelicae Dahuricae, Radix Saposhnikoviae, the Rhizoma Atractylodis Macrocephalae, Folium Hibisci Mutabilis, Folium chrysanthemi, Flos persicae is placed in slow fire boiling in marmite and adds raw Semen Phaseoli after one hour, Semen Persicae pulverizing, the powder that Concha Ostreae (calcined) is broken into, continuation slow fire boiling elimination medicinal residues after a hour, the half that medicine juice adds Semen pruni armeniacae oil dosage in component is oral medicine, medicinal residues and doses remaining Semen pruni armeniacae oil mix are medicine for external use.
Using method: in cicatrization one to three month, use before sleeping evening, once-a-day, oral medicine is oral, each 50ml; Medicine for external use is applied to cicatrix place after cleaning wound surface, and outer layer covers gauze is fixed, and removes gauze early morning and cleans.Remarks, medicine for external use can not be applied to cicatrix place of not healing.Within one week, be a course for the treatment of, general recovery from illness one to three courses for the treatment of.
Clinical trial result illustrates:
For the routine patient of clinical treatment 340 of screening, wherein male patient 153 example, female patient 187 example, patient's max age 62 years old, minimum 3 years old.What patient's keloid area was maximum is 67 square centimeters, minimum 1 square centimeter, and height 0.1-1.3 centimetre is not etc.Without other diseases.Age-based and the state of an illness of above-mentioned patient uses medicine of the present invention, carries out observation of curative effect.
Criterion of therapeutical effect judges:
Recovery from illness, scar tissue color and luster and surrounding skin color and luster and thickness basically identical, the softness that scar tissue hardness is tactile, mobility is good.
Effectively, scar tissue color and luster is thin out before comparatively using, and thickness changes difference and is greater than 0.1cm, and scar tissue hardness alleviates.
Invalid, scar tissue color and luster increases the weight of without improvement or color, and thickness or hardness are without improvement.
Therapeutic outcome is as following table:
As can be known from the above table, after the course for the treatment of of clinical practice, after 83.5%, two courses for the treatment of of medicine total effective rate of the present invention, total effective rate 94.4%, total effective rate 97.9% after three courses for the treatment of, cure rate 89.4%, visible medicine of the present invention has rapid-action, advantage evident in efficacy, and Clinical practice does not all produce the malaise symptoms such as red swelling of the skin, pruritus, prove this product non-evident effect, within clinical latter 1 year, follow up a case by regular visits to and all do not have recurrence.
Model case:
Wang, female, 11 years old, leg boiled water scald, cicatrix area about 27 square centimeters, cicatrix gross thickness 1cm, skin surface is dark red coarse, skin touch just as leather, finger can not have been pinched, and readme sufferings are hard to bear.Use medicine of the present invention, after the course for the treatment of, readme sufferings transference cure, skin surface softens, yellowish-brown liquid is had to flow out, new muscular tissue is had to generate, after using two courses for the treatment of, it is pliable and tough that skin touches, there is certain mobility, can pinch slightly, color dodge, flow out without yellowish-brown liquid, after three courses for the treatment of, the softness that skin touches, mobility is good, cicatrix place skin colour is basic close to consistent with surrounding skin color and luster, for consolidate curative effect, low dose of use a course for the treatment of of medicine of the present invention, follow up a case by regular visits to after 1 year, cicatrix place skin is close to normal skin, there is not recurrence period.
Lee, female, 35 years old, arm scratched, area about 13 square centimeters, cicatrix gross thickness 0.5cm.Voluntary use medicine of the present invention, after two courses for the treatment of, scar thickness is decreased to 0.3cm, and the visible new muscular tissue of naked eyes generates, cicatrix color and luster subtracts light, cicatrix deliquescing, that touches is flexible, but restorative still bad, after three courses for the treatment of, scar thickness is decreased to below 0.1cm, and the softness touched is flexible, and cicatrix color and luster recovers normal substantially.Follow up a case by regular visits to after 1 year, there is not recurrence period.
Fourth, man, 27 years old, acne heals rear face cicatrix of skin seriously, the coarse injustice of skin surface, and color and luster is dark red, conscious puzzlement is serious, and rear use medicine of the present invention, after the course for the treatment of, Skin scar deliquescing, color and luster subtracts light, has impurity to flow out during cleaning, after two courses for the treatment of, Skin scar surface recovery is smooth, and color and luster recovers normal, and that touches is flexible.Follow up a case by regular visits to after 1 year, without recurrence.
Chen, female, 54 years old, finger incised wound, cicatrix area about 2 square centimeters, cicatrix place skin had slight protuberance, and use the present invention cured after the course for the treatment of, and cicatrix place skin recovers normal level and color and luster, conscious hardness and intact skin indifference.Follow up a case by regular visits to after half a year, without recurrence.

Claims (4)

1. treat a medicine for cicatrix, it is characterized in that, described medicine comprises following component:
Flos Carthami 6-12g, Radix Rubiae 6-12g, Fructus Tribuli 3-9g, SHANZHIZI 5-15g, Bulbus Allii Fistulosi 2-8g, Herba Rosmarini Officinalis 3-9g, Radix Oenotherae erythrosepalae 10-20g, Rhizoma Chuanxiong 5-15g, Fructus Crataegi 2-8g, orange blossom 3-9g, Semen pruni armeniacae oil 2-8g, Rhizoma Alpiniae Officinarum 10-20g, Radix Angelicae Dahuricae 6-12g, Concha Ostreae (calcined) 3-9g, Radix Saposhnikoviae 5-15g, Rhizoma Atractylodis Macrocephalae 6-12g, Folium Hibisci Mutabilis 5-15g, Folium chrysanthemi 3-9g, Flos persicae 2-8g, Semen Persicae 2-8g, raw Semen Phaseoli 5-15g.
2. the medicine for the treatment of cicatrix according to claim 1, is characterized in that, described medicine comprises following component:
Flos Carthami 9g, Radix Rubiae 9g, Fructus Tribuli 6g, SHANZHIZI 10g, Bulbus Allii Fistulosi 5g, Herba Rosmarini Officinalis 6g, Radix Oenotherae erythrosepalae 15g, Rhizoma Chuanxiong 10g, Fructus Crataegi 5g, orange blossom 6g, Semen pruni armeniacae oil 5g, Rhizoma Alpiniae Officinarum 15g, Radix Angelicae Dahuricae 9g, Concha Ostreae (calcined) 6g, Radix Saposhnikoviae 10g, Rhizoma Atractylodis Macrocephalae 9g, Folium Hibisci Mutabilis 10g, Folium chrysanthemi 6g, Flos persicae 5g, Semen Persicae 5g, raw Semen Phaseoli 10g.
3. the medicine for the treatment of cicatrix according to claim 1, is characterized in that, described medicine comprises following component:
Flos Carthami 6g, Radix Rubiae 6g, Fructus Tribuli 3g, SHANZHIZI 5g, Bulbus Allii Fistulosi 2g, Herba Rosmarini Officinalis 3g, Radix Oenotherae erythrosepalae 10g, Rhizoma Chuanxiong 5g, Fructus Crataegi 2g, orange blossom 3g, Semen pruni armeniacae oil 2g, Rhizoma Alpiniae Officinarum 10g, Radix Angelicae Dahuricae 6g, Concha Ostreae (calcined) 3g, Radix Saposhnikoviae 5g, Rhizoma Atractylodis Macrocephalae 6g, Folium Hibisci Mutabilis 5g, Folium chrysanthemi 3g, Flos persicae 2g, Semen Persicae 2g, raw Semen Phaseoli 5g.
4. the medicine for the treatment of cicatrix according to claim 1, is characterized in that, described medicine comprises following component:
Flos Carthami 12g, Radix Rubiae 12g, Fructus Tribuli 9g, SHANZHIZI 15g, Bulbus Allii Fistulosi 8g, Herba Rosmarini Officinalis 9g, Radix Oenotherae erythrosepalae 20g, Rhizoma Chuanxiong 15g, Fructus Crataegi 8g, orange blossom 9g, Semen pruni armeniacae oil 8g, Rhizoma Alpiniae Officinarum 20g, Radix Angelicae Dahuricae 12g, Concha Ostreae (calcined) 9g, Radix Saposhnikoviae 15g, Rhizoma Atractylodis Macrocephalae 12g, Folium Hibisci Mutabilis 15g, Folium chrysanthemi 9g, Flos persicae 8g, Semen Persicae 8g, raw Semen Phaseoli 15g.
CN201510087862.7A 2015-02-14 2015-02-14 A kind of medicine for treating scar Expired - Fee Related CN104587353B (en)

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