CN104587238A - Traditional Chinese medicine formula for treating reflux esophagitis and preparation method thereof - Google Patents

Traditional Chinese medicine formula for treating reflux esophagitis and preparation method thereof Download PDF

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CN104587238A
CN104587238A CN201410813252.6A CN201410813252A CN104587238A CN 104587238 A CN104587238 A CN 104587238A CN 201410813252 A CN201410813252 A CN 201410813252A CN 104587238 A CN104587238 A CN 104587238A
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dry
rhizoma
chinese medicine
radix
processed
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陈现忠
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Abstract

The invention belongs to the field of traditional Chinese medicine formulas and in particular relates to a traditional Chinese medicine formula for treating reflux esophagitis. The traditional Chinese medicine formula is formed by the following raw materials by weight: 3-5g of coptis root, 1-2g of cassia bark, 8-12g of cinnabar root poria, 20-30g of tuber fleeceflower stem, 10-15g of bamboo shavings, 8-12g of fried immature bitter orange, 8-12g of ternate pinellia, 8-12g of dried tangerine peel, 1-2g of medicinal evodia fruit, 10-20g of roasted cuttlebone, 10-15g of fruit of fiverleaf akebia, 10-15g of pseudobulb of appendiculate cremastra, 8-12g of prepared rhubarb, 15-25g of virgate wormwood herb, 8-12g of green tangerine peel, 3-8g of radix bupleuri and 8-12g of red paeony root. The traditional Chinese medicine formula has the beneficial effects that the traditional Chinese medicines have the advantages of simple components, low price, short course of treatment, good curative effects, high cure rate, and the like; through statistics after the medicine is taken for a course of treatment which lasts a week, the effective rate is 100%, the cure rate is 96% and the improvement rate is 6%; the product is rich in raw materials; a preparation method is simple and feasible.

Description

Chinese medicine formula of a kind of reflux esophagitis and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese medicine formula, be specifically related to Chinese medicine formula of a kind of reflux esophagitis and preparation method thereof.
Background technology
Reflux esophagitis (RE) enters by Stomach duodenum content reflux the esophagitis sexually transmitted disease (STD) that esophagus causes to become, and Endoscopic Features is the breakage of Esophageal Mucosa, i.e. rotten to the corn the and (or) esophageal ulcer of esophagus.Reflux esophagitis can betide the crowd at any age, and Adult Onset leads and increases with the age and raise.Hesperian sickness rate is high, and Asia sickness rate is low.This geographic difference may be relevant with h and E factor.But the sickness rate in the recent two decades whole world is all on the rise.Middle-aged and elderly people, obesity, smoking, to drink and stress is greatly the group of people at high risk of reflux esophagitis.At present, Western medicine cannot effectively be treated, and has certain side effect, and therefore, people exist great demand to the Chinese medicine of effectively treating reflux esophagitis.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine formula of reflux esophagitis.
The present invention is achieved through the following technical solutions:
A Chinese medicine formula for reflux esophagitis, is made up of following raw material by weight: Rhizoma Coptidis 3-5g, Cortex Cinnamomi 1-2g, Poria 8-12g, Caulis Polygoni Multiflori 20-30g, Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens) 10-15g, Fructus Aurantii Immaturus (parched) 8-12g, Rhizoma Pinelliae Preparatum 8-12g, Pericarpium Citri Reticulatae 8-12g, Fructus Evodiae 1-2g, process Os Sepiae 10-20g, Fructus Akebiae 10-15g, Pseudobulbus Cremastrae Seu Pleiones 10-15g, Radix et Rhizoma Rhei (processed) 8-12g, Herba Artemisiae Scopariae 15-25g, Pericarpium Citri Reticulatae Viride 8-12g, Radix Bupleuri 3-8g, Radix Paeoniae Rubra 8-12g.
Preferred scheme is made up of following raw material by weight: Rhizoma Coptidis 4g, Cortex Cinnamomi 1g, Poria 10g, Caulis Polygoni Multiflori 25g, Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens) 12g, Fructus Aurantii Immaturus (parched) 10g, Rhizoma Pinelliae Preparatum 10g, Pericarpium Citri Reticulatae 10g, Fructus Evodiae 1.5g, process Os Sepiae 15g, Fructus Akebiae 12g, Pseudobulbus Cremastrae Seu Pleiones 12g, Radix et Rhizoma Rhei (processed) 10g, Herba Artemisiae Scopariae 20g, Pericarpium Citri Reticulatae Viride 10g, Radix Bupleuri 5g, Radix Paeoniae Rubra 10g.
A preparation method for the Chinese medicine formula of reflux esophagitis, comprises the following steps:
(1) Chinese medicine is joined
(1) Rhizoma Coptidis: removing impurity, puts in boiling water and boils 10 minutes, take out, vexed, and shave is dry;
(2) Cortex Cinnamomi: removing impurity and rough bark.Used time smashs to pieces;
(3) Poria: by former medicine removing impurity, sieve dedust bits;
(4) Caulis Polygoni Multiflori: clear water is cleaned, and slightly soak, pull out, after running through, cutting, dries;
(5) Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens): get clean Caulis Bambusae In Taenia, mix thoroughly with Sucus Zingberis, puts in pot and fries to yellow with slow fire, take out, dry;
(6) Fructus Aurantii Immaturus (parched): first wheat bran is removed even in the pot of heating, when marquis's cigarette is emerged, add Fructus Aurantii Immaturus sheet, stir to micro-in coke yellow, take out, sieve removes wheat bran, cools;
(7) Rhizoma Pinelliae Preparatum: get the clean Rhizoma Pinelliae, size separately, is soaked in water to interior without the dry heart, takes out, and cleans, dries in the shade or dry;
(8) Pericarpium Citri Reticulatae: removing impurity, shower water, runs through, shredding, dry;
(9) Fructus Evodiae: removing impurity, dry;
(10) process Os Sepiae: scrub clean, dry, pound into fritter;
(11) Fructus Akebiae: dry after soaking with boiling water;
(12) Pseudobulbus Cremastrae Seu Pleiones: removing impurity, water logging about 1 hour, runs through, shave, dry or clean dry, and the used time smashs to pieces;
(13) Radix et Rhizoma Rhei (processed): get rhubarb tablets yellow wine and evenly spray, micro-stewing, put the micro-stir-fry of the interior slow fire of pot, taking-up is dried;
(14) Herba Artemisiae Scopariae: removing undesirable root and impurity, rubs broken or chopping with the hands.Capillary wormwood sieve dedust bits;
(15) Pericarpium Citri Reticulatae Viride: removing impurity, clean, moistening, cuts sheet or silk, dries;
(16) Radix Bupleuri: decontamination and residual stem, cleans, runs through, cut sheet, dry;
(17) Radix Paeoniae Rubra: get Radix Paeoniae Rubra sheet, puts in preheating parch container, and with slow fire heating, fry to color burn, taking-up is dried in the air cool, and sieve removes chip;
(2) prepare
First will process Os Sepiae to put into water by described weight and decoct 15 minutes, by the Rhizoma Coptidis of described weight, Poria, Caulis Polygoni Multiflori, Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens), Fructus Aurantii Immaturus (parched), Rhizoma Pinelliae Preparatum, Pericarpium Citri Reticulatae, process Os Sepiae, Fructus Akebiae, Pseudobulbus Cremastrae Seu Pleiones, Radix et Rhizoma Rhei (processed), Herba Artemisiae Scopariae, Pericarpium Citri Reticulatae Viride, Radix Bupleuri, Radix Paeoniae Rubra plurality of Chinese composition 5 times amount that add water soak, slow fire boiling 15 minutes, intense fire decocts boiling 15 minutes, use slow fire boiling again 10 minutes, must medicinal liquid be decocted the Cortex Cinnamomi and Fructus Evodiae boiled water of putting into described weight.
Pharmacology analysis: the cause of disease such as obstacle, the gastroduodenal malfunction initiation of being cleaned up function more than stomachache by the infringement of Esophageal Mucosa anti-reflux barrier function, esophageal acid; Mainly contain burn feeling (heartburn) after breastbone, reflux and chest pain, the chronic symptom such as hemorrhage on a small quantity, have removing heat-phlegm in prescription, relieve restlessness and prevent vomiting, dissipating phlegm and resolving masses, depressed liver-energy dispersing and QI regulating, astringing to arrest bleeding, dispersing cold for relieving pain effect; We's pharmaceutically dosage form is decoction, is decocted in water for oral dose, and potion on the one decocts twice, warm water delivery service, and period in a medicine avoids pungent food cold and cool and greasy, heavy food.
Beneficial effect of the present invention: Chinese medicine of the present invention has that prescription is simple, low price, short treating period, good effect, cure rate advantages of higher, with the statistics that is as the criterion course for the treatment of Monday of taking medicine, effective percentage 100%, cure rate 96%, improvement 6%, this products material is abundant, manufacture method is simple and easy to do.
Detailed description of the invention
Embodiment 1
A Chinese medicine formula for reflux esophagitis, weight portion is made up of following raw material: Rhizoma Coptidis 4g, Cortex Cinnamomi 1g, Poria 10g, Caulis Polygoni Multiflori 25g, Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens) 12g, Fructus Aurantii Immaturus (parched) 10g, Rhizoma Pinelliae Preparatum 10g, Pericarpium Citri Reticulatae 10g, Fructus Evodiae 1.5g, process Os Sepiae 15g, Fructus Akebiae 12g, Pseudobulbus Cremastrae Seu Pleiones 12g, Radix et Rhizoma Rhei (processed) 10g, Herba Artemisiae Scopariae 20g, Pericarpium Citri Reticulatae Viride 10g, Radix Bupleuri 5g, Radix Paeoniae Rubra 10g.
A Chinese medicine formula for reflux esophagitis, comprises the following steps:
(1) Chinese medicine is joined
(1) Rhizoma Coptidis: removing impurity, puts in boiling water and boils 10 minutes, take out, vexed, and shave is dry;
(2) Cortex Cinnamomi: removing impurity and rough bark.Used time smashs to pieces;
(3) Poria: by former medicine removing impurity, sieve dedust bits;
(4) Caulis Polygoni Multiflori: clear water is cleaned, and slightly soak, pull out, after running through, cutting, dries;
(5) Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens): get clean Caulis Bambusae In Taenia, mix thoroughly with Sucus Zingberis, puts in pot and fries to yellow with slow fire, take out, dry;
(6) Fructus Aurantii Immaturus (parched): first wheat bran is removed even in the pot of heating, when marquis's cigarette is emerged, add Fructus Aurantii Immaturus sheet, stir to micro-in coke yellow, take out, sieve removes wheat bran, cools;
(7) Rhizoma Pinelliae Preparatum: get the clean Rhizoma Pinelliae, size separately, is soaked in water to interior without the dry heart, takes out, and cleans, dries in the shade or dry;
(8) Pericarpium Citri Reticulatae: removing impurity, shower water, runs through, shredding, dry;
(9) Fructus Evodiae: removing impurity, dry;
(10) process Os Sepiae: scrub clean, dry, pound into fritter;
(11) Fructus Akebiae: dry after soaking with boiling water;
(12) Pseudobulbus Cremastrae Seu Pleiones: removing impurity, water logging about 1 hour, runs through, shave, dry or clean dry, and the used time smashs to pieces;
(13) Radix et Rhizoma Rhei (processed): get rhubarb tablets yellow wine and evenly spray, micro-stewing, put the micro-stir-fry of the interior slow fire of pot, taking-up is dried;
(14) Herba Artemisiae Scopariae: removing undesirable root and impurity, rubs broken or chopping with the hands.Capillary wormwood sieve dedust bits;
(15) Pericarpium Citri Reticulatae Viride: removing impurity, clean, moistening, cuts sheet or silk, dries;
(16) Radix Bupleuri: decontamination and residual stem, cleans, runs through, cut sheet, dry;
(17) Radix Paeoniae Rubra: get Radix Paeoniae Rubra sheet, puts in preheating parch container, and with slow fire heating, fry to color burn, taking-up is dried in the air cool, and sieve removes chip;
(2) prepare
First will process Os Sepiae to put into water by described weight and decoct 15 minutes, by the Rhizoma Coptidis of described weight, Poria, Caulis Polygoni Multiflori, Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens), Fructus Aurantii Immaturus (parched), Rhizoma Pinelliae Preparatum, Pericarpium Citri Reticulatae, process Os Sepiae, Fructus Akebiae, Pseudobulbus Cremastrae Seu Pleiones, Radix et Rhizoma Rhei (processed), Herba Artemisiae Scopariae, Pericarpium Citri Reticulatae Viride, Radix Bupleuri, Radix Paeoniae Rubra plurality of Chinese composition 5 times amount that add water soak, slow fire boiling 15 minutes, intense fire decocts boiling 15 minutes, use slow fire boiling again 10 minutes, must medicinal liquid be decocted the Cortex Cinnamomi and Fructus Evodiae boiled water of putting into described weight.
Embodiment 2
A Chinese medicine formula for reflux esophagitis, weight portion is made up of following raw material: Rhizoma Coptidis 4g, Cortex Cinnamomi 1g, Poria 10g, Caulis Polygoni Multiflori 25g, Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens) 12g, Fructus Aurantii Immaturus (parched) 10g, Rhizoma Pinelliae Preparatum 10g, Pericarpium Citri Reticulatae 10g, Fructus Evodiae 1.5g, process Os Sepiae 15g, Fructus Akebiae 12g, Pseudobulbus Cremastrae Seu Pleiones 12g, Radix et Rhizoma Rhei (processed) 10g, Herba Artemisiae Scopariae 20g, Pericarpium Citri Reticulatae Viride 10g, Radix Bupleuri 5g, Radix Paeoniae Rubra 10g.
A Chinese medicine formula for reflux esophagitis, comprises the following steps:
(1) Chinese medicine is joined
(1) Rhizoma Coptidis: removing impurity, puts in boiling water and boils 10 minutes, take out, vexed, and shave is dry;
(2) Cortex Cinnamomi: removing impurity and rough bark.Used time smashs to pieces;
(3) Poria: by former medicine removing impurity, sieve dedust bits;
(4) Caulis Polygoni Multiflori: clear water is cleaned, and slightly soak, pull out, after running through, cutting, dries;
(5) Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens): get clean Caulis Bambusae In Taenia, mix thoroughly with Sucus Zingberis, puts in pot and fries to yellow with slow fire, take out, dry;
(6) Fructus Aurantii Immaturus (parched): first wheat bran is removed even in the pot of heating, when marquis's cigarette is emerged, add Fructus Aurantii Immaturus sheet, stir to micro-in coke yellow, take out, sieve removes wheat bran, cools;
(7) Rhizoma Pinelliae Preparatum: get the clean Rhizoma Pinelliae, size separately, is soaked in water to interior without the dry heart, takes out, and cleans, dries in the shade or dry;
(8) Pericarpium Citri Reticulatae: removing impurity, shower water, runs through, shredding, dry;
(9) Fructus Evodiae: removing impurity, dry;
(10) process Os Sepiae: scrub clean, dry, pound into fritter;
(11) Fructus Akebiae: dry after soaking with boiling water;
(12) Pseudobulbus Cremastrae Seu Pleiones: removing impurity, water logging about 1 hour, runs through, shave, dry or clean dry, and the used time smashs to pieces;
(13) Radix et Rhizoma Rhei (processed): get rhubarb tablets yellow wine and evenly spray, micro-stewing, put the micro-stir-fry of the interior slow fire of pot, taking-up is dried;
(14) Herba Artemisiae Scopariae: removing undesirable root and impurity, rubs broken or chopping with the hands.Capillary wormwood sieve dedust bits;
(15) Pericarpium Citri Reticulatae Viride: removing impurity, clean, moistening, cuts sheet or silk, dries;
(16) Radix Bupleuri: decontamination and residual stem, cleans, runs through, cut sheet, dry;
(17) Radix Paeoniae Rubra: get Radix Paeoniae Rubra sheet, puts in preheating parch container, and with slow fire heating, fry to color burn, taking-up is dried in the air cool, and sieve removes chip;
(2) prepare
First will process Os Sepiae to put into water by described weight and decoct 15 minutes, by the Rhizoma Coptidis of described weight, Poria, Caulis Polygoni Multiflori, Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens), Fructus Aurantii Immaturus (parched), Rhizoma Pinelliae Preparatum, Pericarpium Citri Reticulatae, process Os Sepiae, Fructus Akebiae, Pseudobulbus Cremastrae Seu Pleiones, Radix et Rhizoma Rhei (processed), Herba Artemisiae Scopariae, Pericarpium Citri Reticulatae Viride, Radix Bupleuri, Radix Paeoniae Rubra plurality of Chinese composition 5 times amount that add water soak, slow fire boiling 15 minutes, intense fire decocts boiling 15 minutes, use slow fire boiling again 10 minutes, must medicinal liquid be decocted the Cortex Cinnamomi and Fructus Evodiae boiled water of putting into described weight.

Claims (3)

1. the Chinese medicine formula of a reflux esophagitis, it is characterized in that, be made up of following raw material by weight: Rhizoma Coptidis 3-5g, Cortex Cinnamomi 1-2g, Poria 8-12g, Caulis Polygoni Multiflori 20-30g, Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens) 10-15g, Fructus Aurantii Immaturus (parched) 8-12g, Rhizoma Pinelliae Preparatum 8-12g, Pericarpium Citri Reticulatae 8-12g, Fructus Evodiae 1-2g, process Os Sepiae 10-20g, Fructus Akebiae 10-15g, Pseudobulbus Cremastrae Seu Pleiones 10-15g, Radix et Rhizoma Rhei (processed) 8-12g, Herba Artemisiae Scopariae 15-25g, Pericarpium Citri Reticulatae Viride 8-12g, Radix Bupleuri 3-8g, Radix Paeoniae Rubra 8-12g.
2. the Chinese medicine formula of a kind of reflux esophagitis according to claim 1, it is characterized in that, be made up of following raw material by weight: Rhizoma Coptidis 4g, Cortex Cinnamomi 1g, Poria 10g, Caulis Polygoni Multiflori 25g, Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens) 12g, Fructus Aurantii Immaturus (parched) 10g, Rhizoma Pinelliae Preparatum 10g, Pericarpium Citri Reticulatae 10g, Fructus Evodiae 1.5g, process Os Sepiae 15g, Fructus Akebiae 12g, Pseudobulbus Cremastrae Seu Pleiones 12g, Radix et Rhizoma Rhei (processed) 10g, Herba Artemisiae Scopariae 20g, Pericarpium Citri Reticulatae Viride 10g, Radix Bupleuri 5g, Radix Paeoniae Rubra 10g.
3. a kind of preparation method of Chinese medicine formula of reflux esophagitis according to claim 1 or 2, is characterized in that: comprise the following steps:
(1) Chinese medicine is joined
(1) Rhizoma Coptidis: removing impurity, puts in boiling water and boils 10 minutes, take out, vexed, and shave is dry;
(2) Cortex Cinnamomi: removing impurity and rough bark, the used time smashs to pieces;
(3) Poria: by former medicine removing impurity, sieve dedust bits;
(4) Caulis Polygoni Multiflori: clear water is cleaned, and slightly soak, pull out, after running through, cutting, dries;
(5) Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens): get clean Caulis Bambusae In Taenia, mix thoroughly with Sucus Zingberis, puts in pot and fries to yellow with slow fire, take out, dry;
(6) Fructus Aurantii Immaturus (parched): first wheat bran is removed even in the pot of heating, when marquis's cigarette is emerged, add Fructus Aurantii Immaturus sheet, stir to micro-in coke yellow, take out, sieve removes wheat bran, cools;
(7) Rhizoma Pinelliae Preparatum: get the clean Rhizoma Pinelliae, size separately, is soaked in water to interior without the dry heart, takes out, and cleans, dries in the shade or dry;
(8) Pericarpium Citri Reticulatae: removing impurity, shower water, runs through, shredding, dry;
(9) Fructus Evodiae: removing impurity, dry;
(10) process Os Sepiae: scrub clean, dry, pound into fritter;
(11) Fructus Akebiae: dry after soaking with boiling water;
(12) Pseudobulbus Cremastrae Seu Pleiones: removing impurity, water logging about 1 hour, runs through, shave, dry or clean dry, and the used time smashs to pieces;
(13) Radix et Rhizoma Rhei (processed): get rhubarb tablets yellow wine and evenly spray, micro-stewing, put the micro-stir-fry of the interior slow fire of pot, taking-up is dried;
(14) Herba Artemisiae Scopariae: removing undesirable root and impurity, rubs broken or chopping with the hands, capillary wormwood sieve dedust bits;
(15) Pericarpium Citri Reticulatae Viride: removing impurity, clean, moistening, cuts sheet or silk, dries;
(16) Radix Bupleuri: decontamination and residual stem, cleans, runs through, cut sheet, dry;
(17) Radix Paeoniae Rubra: get Radix Paeoniae Rubra sheet, puts in preheating parch container, and with slow fire heating, fry to color burn, taking-up is dried in the air cool, and sieve removes chip;
(2) prepare
First will process Os Sepiae to put into water by described weight and decoct 15 minutes, by the Rhizoma Coptidis of described weight, Poria, Caulis Polygoni Multiflori, Caulis Bambusae In Taenia (processed with Rhizoma Zingiberis Recens), Fructus Aurantii Immaturus (parched), Rhizoma Pinelliae Preparatum, Pericarpium Citri Reticulatae, process Os Sepiae, Fructus Akebiae, Pseudobulbus Cremastrae Seu Pleiones, Radix et Rhizoma Rhei (processed), Herba Artemisiae Scopariae, Pericarpium Citri Reticulatae Viride, Radix Bupleuri, Radix Paeoniae Rubra plurality of Chinese composition 5 times amount that add water soak, slow fire boiling 15 minutes, intense fire decocts boiling 15 minutes, use slow fire boiling again 10 minutes, must medicinal liquid be decocted the Cortex Cinnamomi and Fructus Evodiae boiled water of putting into described weight.
CN201410813252.6A 2014-12-24 2014-12-24 Traditional Chinese medicine formula for treating reflux esophagitis and preparation method thereof Pending CN104587238A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170091873A (en) * 2016-02-02 2017-08-10 대구한의대학교산학협력단 Pharmaceutical composition having extract of rhei rhizoma and coptis chinensis for prevention or treatment of reflux esophagitis

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101829310A (en) * 2010-05-06 2010-09-15 杜山鹏 Traditional Chinese medicine preparation for treating reflux esophagitis
CN102631553A (en) * 2012-05-02 2012-08-15 马守云 Medicament for treating reflux esophagitis
CN103083631A (en) * 2012-12-11 2013-05-08 宋协勘 Traditional Chinese medicine for treating reflux esophagitis
CN103495040A (en) * 2013-10-12 2014-01-08 山东科技大学 Traditional Chinese medicine composition for treating reflux esophagitis and preparation method of granule formulation thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101829310A (en) * 2010-05-06 2010-09-15 杜山鹏 Traditional Chinese medicine preparation for treating reflux esophagitis
CN102631553A (en) * 2012-05-02 2012-08-15 马守云 Medicament for treating reflux esophagitis
CN103083631A (en) * 2012-12-11 2013-05-08 宋协勘 Traditional Chinese medicine for treating reflux esophagitis
CN103495040A (en) * 2013-10-12 2014-01-08 山东科技大学 Traditional Chinese medicine composition for treating reflux esophagitis and preparation method of granule formulation thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20170091873A (en) * 2016-02-02 2017-08-10 대구한의대학교산학협력단 Pharmaceutical composition having extract of rhei rhizoma and coptis chinensis for prevention or treatment of reflux esophagitis
KR101894627B1 (en) * 2016-02-02 2018-09-03 대구한의대학교산학협력단 Pharmaceutical composition having extract of rhei rhizoma and coptis chinensis for prevention or treatment of reflux esophagitis

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Application publication date: 20150506