CN104585168A - Foam type ethanol disinfection solution - Google Patents
Foam type ethanol disinfection solution Download PDFInfo
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- CN104585168A CN104585168A CN201310523342.7A CN201310523342A CN104585168A CN 104585168 A CN104585168 A CN 104585168A CN 201310523342 A CN201310523342 A CN 201310523342A CN 104585168 A CN104585168 A CN 104585168A
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Abstract
The invention relates to a foam type ethanol disinfection solution and a preparation method thereof. The foam type ethanol disinfection solution comprises 40-80 wt% of ethanol, 1-5 wt% of PEG-23 lauryl ether, 0.5-1.5 wt% of polyoxyethylene 10 behenyl ether, 0.1-1 wt% of cocamidopropyl PG-dimonium chloride phosphate, 0.1-1 wt% of a foam stabilizing agent, 0.5-2 wt% of a skin-moistening agent, and the balance water. The preparation method comprises: adding the foam stabilizing agent into ethanol according to the proportions, and stirring for dissolving, so as to obtain a solution A; adding PEG-23 lauryl ether and polyoxyethylene 10 behenyl ether into water, heating to 50-60 DEG C and stirring for dissolving, and cooling to 30 DEG C or less, so as to obtain a solution B; adding the solution A into the solution B, then adding cocamidopropyl PG-dimonium chloride phosphate and the skin-moistening agent, and stirring uniformly, so as to obtain the foam type ethanol disinfection solution. The foam type ethanol disinfection solution is stable in properties, and can generate fine stable foams after being pressed by a foam pump.
Description
Technical field
The present invention relates to hand hygiene articles for use, particularly relate to a kind of thimerosal of ethanol class.
Background technology
Ethanol is a kind of conventional disinfectant, has the characteristic of quick kill vegetative forms of bacteria and mycobacterium, fungi sporozoite, lipophilic virus.Be that the disinfectant of major antibacterial composition is widely used in medical treatment and field of public health with ethanol.Ethanol disinfection agent conventional in the market occurs mainly with liquid or gel form.Liquid is easily trickled down in use, operates very inconvenient, and can affect Disinfection Effect because embrocating uneven.Gel rubber system stiff, stretchability deviation, and have obvious sticky sense after using.Tracing it to its cause, is the problem of surfactant.
CN 101083908 B provides a kind of surfactant, it is silicone compounds mainly, such as, dimethyl silicone polymer, PSI, annular siloxane and the silicone compounds with amino, fatty acid, alcohol, polyethers, epoxy, fluorine, glucosides and/or alkyl group modification.Preferably as silicone compounds of the present invention is polysiloxane-polyether copolymer [INCI (CFTA): dimethicone copolyol], sold with trade name ABIL by the Goldschmidt company of hsen, especially the polysiloxane-polyether copolymer of B88 product line, such as, ABIL B 8843, ABIL B 885UABIL0B 8852, ABEL B 8863, ABEL B 88183 and ABIL B 88184.Particularly preferably be, foam compositions of the present invention comprises, as components b), the polysiloxane-polyether copolymer sold with trade name ABIL B 8832 (two-PEG/PPG-20/20 dimethyl silicone polymer).
Although CN 101083908 B provides solution, this kind realizes domestic as the silicone compounds failing of surfactant, and raw material supplying and use are subject to the restriction of overseas enterprise.
Summary of the invention
The present invention is intended to solve the problem, and provides a kind of foam type ethanol disinfection liquid.Foam type ethanol disinfection liquid stable in properties provided by the invention, through foam pump pressing liquid draining, can produce fine and smooth stable foam, volatilize speed fast after using, gentle non-stimulated, and does not limit by foreign enterprise.
For solving the problem, a kind of foam type ethanol disinfection liquid, it comprises each component of following each percetage by weight:
Ethanol: 40-80;
PEG-23 lauryl alcohol: 1-5;
Polyoxyethylene (10) docosyl alcohol ether: 0.5-1.5;
Cocamidopropyl propyl amide pg dimonium chloride phosphate: 0.1-1;
Foam stabilizer: 0.1-1;
Emollient: 0.5-2;
Water: surplus;
Wherein said foam stabilizer is zein and/or PVP K-30; Described emollient is olive oil PEG-7 ester or PEG-26 glycerin ether.
Described foam type ethanol disinfection liquid, the ratio of the PEG-23 lauryl alcohol in the weight ratio of described component, polyoxyethylene (10) docosyl alcohol ether and foam stabilizer is 1:0.15-0.3:0.05-0.2.
The preparation method of described foam type ethanol disinfection liquid, the method is: by described component and content, is added by foam stabilizer in ethanol, stirring and dissolving, obtains A liquid; PEG-23 lauryl alcohol and polyoxyethylene (10) docosyl alcohol ether are added to the water, are heated to 50-60 DEG C, stirring and dissolving, obtain B liquid; Treat that B liquid is cooled to less than 30 DEG C, A liquid is added B liquid, is uniformly mixed; Add cocamidopropyl propyl amide pg dimonium chloride phosphate, stir; Finally with emollient, stir, obtain described foam type ethanol disinfection liquid.
The present invention adopts complexed surfactant, and particularly the self-emulsifying properties of polyoxyethylene (10) docosyl alcohol ether, strengthens the foamability of compound system greatly.The present invention adopts macromolecular compound as foam stabilizer, and macromolecular compound forms network type structure at foam surface, plays the effect of stable foam form.
Embodiment
A kind of foam type ethanol disinfection of the present invention liquid, it comprises each component of following each percetage by weight:
Ethanol: 40-80;
PEG-23 lauryl alcohol: 1-5;
Polyoxyethylene (10) docosyl alcohol ether: 0.5-1.5;
Cocamidopropyl propyl amide pg dimonium chloride phosphate: 0.1-1;
Foam stabilizer: 0.1-1;
Emollient: 0.5-2;
Water: surplus;
Wherein said foam stabilizer is zein and/or PVP K-30; Described emollient is olive oil PEG-7 ester or PEG-26 glycerin ether.
Described foam type ethanol disinfection liquid, the ratio of the PEG-23 lauryl alcohol in the weight ratio of described component, polyoxyethylene (10) docosyl alcohol ether and foam stabilizer is 1:0.15-0.3:0.05-0.2.
The preparation method of described foam type ethanol disinfection liquid, the method is: by described component and content, is added by foam stabilizer in ethanol, stirring and dissolving, obtains A liquid; PEG-23 lauryl alcohol and polyoxyethylene (10) docosyl alcohol ether are added to the water, are heated to 50-60 DEG C, stirring and dissolving, obtain B liquid; Treat that B liquid is cooled to less than 30 DEG C, A liquid is added B liquid, is uniformly mixed; Add cocamidopropyl propyl amide pg dimonium chloride phosphate, stir; Finally with emollient, stir, obtain described foam type ethanol disinfection liquid.
Embodiment 1
Added by zein 3 grams in ethanol 400 grams, stirring and dissolving, obtains A liquid; PEG-23 lauryl alcohol 20 grams and 6 grams, polyoxyethylene (10) docosyl alcohol ether are added in 551 grams of water, is heated to 50-60 DEG C, stirring and dissolving, obtains B liquid; Treat that B liquid is cooled to less than 30 DEG C, A liquid is added B liquid, is uniformly mixed; Add cocamidopropyl propyl amide pg dimonium chloride phosphate 10 grams, stir; Finally add olive oil PEG-7 ester 10 grams, stir, obtain described foam type ethanol disinfection liquid.
Embodiment 2
Add in ethanol 600 grams by zein 5 grams and PVP K-30 5 grams, stirring and dissolving, obtains A liquid; PEG-23 lauryl alcohol 50 grams and 10 grams, polyoxyethylene (10) docosyl alcohol ether are added in 305 grams of water, is heated to 50-60 DEG C, stirring and dissolving, obtains B liquid; Treat that B liquid is cooled to less than 30 DEG C, A liquid is added B liquid, is uniformly mixed; Add cocamidopropyl propyl amide pg dimonium chloride phosphate 5 grams, stir; Finally add olive oil PEG-7 ester 20 grams, stir, obtain described foam type ethanol disinfection liquid.
Embodiment 3
Added by PVP K-30 5 grams in ethanol 800 grams, stirring and dissolving, obtains A liquid; PEG-23 lauryl alcohol 30 grams and 5 grams, polyoxyethylene (10) docosyl alcohol ether are added in 150 grams of water, is heated to 50-60 DEG C, stirring and dissolving, obtains B liquid; Treat that B liquid is cooled to less than 30 DEG C, A liquid is added B liquid, is uniformly mixed; Add cocamidopropyl propyl amide pg dimonium chloride phosphate 5 grams, stir; Finally add PEG-26 glycerin ether 5 grams, stir, obtain described foam type ethanol disinfection liquid.
Foam type ethanol disinfection liquid stable in properties as obtained in above-described embodiment, through foam pump pressing liquid draining, can produce fine and smooth stable foam, gentle non-stimulated, volatilize speed after using fast, skinfeel is smooth without sticky.
Claims (3)
1. a foam type ethanol disinfection liquid, it comprises each component of following each percetage by weight:
Ethanol: 40-80;
PEG-23 lauryl alcohol: 1-5;
Polyoxyethylene (10) docosyl alcohol ether: 0.5-1.5;
Cocamidopropyl propyl amide pg dimonium chloride phosphate: 0.1-1;
Foam stabilizer: 0.1-1;
Emollient: 0.5-2;
Water: surplus;
Wherein said foam stabilizer is zein and/or PVP K-30; Described emollient is olive oil PEG-7 ester or PEG-26 glycerin ether.
2. foam type ethanol disinfection liquid according to claim 1, is characterized in that, the ratio of the PEG-23 lauryl alcohol in the weight ratio of described component, polyoxyethylene (10) docosyl alcohol ether and foam stabilizer is 1:0.15-0.3:0.05-0.2.
3. the preparation method of foam type ethanol disinfection liquid according to claim 1 and 2, it is characterized in that, the method is: by described component and content, is added by foam stabilizer in ethanol, stirring and dissolving, obtains A liquid; PEG-23 lauryl alcohol and polyoxyethylene (10) docosyl alcohol ether are added to the water, are heated to 50-60 DEG C, stirring and dissolving, obtain B liquid; Treat that B liquid is cooled to less than 30 DEG C, A liquid is added B liquid, is uniformly mixed; Add cocamidopropyl propyl amide pg dimonium chloride phosphate, stir; Finally with emollient, stir, obtain described foam type ethanol disinfection liquid.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310523342.7A CN104585168A (en) | 2013-10-30 | 2013-10-30 | Foam type ethanol disinfection solution |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201310523342.7A CN104585168A (en) | 2013-10-30 | 2013-10-30 | Foam type ethanol disinfection solution |
Publications (1)
| Publication Number | Publication Date |
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| CN104585168A true CN104585168A (en) | 2015-05-06 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201310523342.7A Pending CN104585168A (en) | 2013-10-30 | 2013-10-30 | Foam type ethanol disinfection solution |
Country Status (1)
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| CN (1) | CN104585168A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113349199A (en) * | 2021-06-30 | 2021-09-07 | 无锡宏霸医疗科技有限公司 | Foam type ethanol-free washing-free disinfectant |
| CN114763362A (en) * | 2021-05-27 | 2022-07-19 | 上海禾琅化工有限公司 | Preparation of cocamidopropyl-PG-dimethylammonium chloride phosphate, product and product |
-
2013
- 2013-10-30 CN CN201310523342.7A patent/CN104585168A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114763362A (en) * | 2021-05-27 | 2022-07-19 | 上海禾琅化工有限公司 | Preparation of cocamidopropyl-PG-dimethylammonium chloride phosphate, product and product |
| CN113349199A (en) * | 2021-06-30 | 2021-09-07 | 无锡宏霸医疗科技有限公司 | Foam type ethanol-free washing-free disinfectant |
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| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
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| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20150506 |
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| RJ01 | Rejection of invention patent application after publication |