CN104574316B - A kind of digitized X-ray machine system - Google Patents

A kind of digitized X-ray machine system Download PDF

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CN104574316B
CN104574316B CN201510014273.6A CN201510014273A CN104574316B CN 104574316 B CN104574316 B CN 104574316B CN 201510014273 A CN201510014273 A CN 201510014273A CN 104574316 B CN104574316 B CN 104574316B
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CN104574316A (en
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钱宇
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NANJING BAINENGWEI MEDICAL TECHNOLOGY Co Ltd
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Abstract

The invention discloses a kind of digitized X-ray machine systems, the system includes wireless DR tablets, MINI PACS, image processing software, remote medical consultation with specialists workflow personalization system, MINI PACS can realize remote medical consultation with specialists function and tele-medicine function both domestic and external as the storage of image, transmission and management system;Image processing software includes full-automatic imaging noise reduction algorithm packet and intelligent picture superposition algorithm packet.The digitized X-ray machine system of the present invention has concentrated direct digital radiograph, imaging, Image Management, storage, transmission, full-automatic imaging noise reduction algorithm has achieved the effect that the maximum reservation to resolution ratio and the maximum enhancing of image detail contrast, intelligent picture superposition algorithm can clearly show each detail content for the intelligent image enhancement of different zones, realize " Z-operation " diagnosis of radiologist, PACS system realizes remote medical consultation with specialists function and the present invention realizes the integration of software and hardware.

Description

A kind of digitized X-ray machine system
Technical field
The invention belongs to medical imaging field more particularly to a kind of digitized X-ray machine systems.
Background technology
The medical imaging Processing Algorithm of traditional imaging algorithm utilizes such as Laplacian gold words more on realizing decrease of noise functions Spatially Fourier's variation is done in frequency layering to tower, and such algorithm will produce a large amount of artificial artifact, also irreversible in noise reduction process Remove some important picture materials and details.
The imaging algorithm that manufacturer's majority uses independent development is given birth to by the digital medical image documentation equipment of representative of Agfa by foreign countries, If the MUSICA2 of Agfa uses multiband image enhancement processing technology, spatially the height of frequency is low splits piece image At 12 different levels (frequency), according to different application fields, different degrees of enhancing, suppression are carried out to each frequency range respectively System, contrast, the adjusting of window width and window level, the enhancing at edge and treatment of details.Common medical imaging Processing Algorithm utilizes such as more Spatially Fourier's variation is done in frequency layering to Laplacian pyramids, and the high-frequency region concentrated to details and noise carries out denoising Enhance with details, low frequency region retain or slightly handles, then inversefouriertransform slice.This method is not intelligent, Details is inevitably removed when handling high-frequency noise.Most of manufacturers are had purchased due to the limitation of technology and fund It is third party's image processing algorithms of representative as the core of imaging software using U.S. Context Vision.Though such combination Complete imaging system can so be formed in a short time, but due to hardware and design difference, experimental data is limited etc., and reasons, processing are calculated Method can only carry out limited image procossing in the case where passively obtaining data, be difficult to obtain best effective on being ultimately imaged effect Fruit.Including GE, Carestream medical treatment medical giant inside, due to medical treatment, educational resource and the traditional factor of scientific research, research and development production The phenomenon that product and characteristic Occidentalize is serious.The rarer clinic or experiment for asian population of product.Asian population and occidentals Group is in fitness, and body structure, body shape, which has, generally to be distinguished, from the recommended value of film making parameter to Image Processing parameter Setting has error.
Traditional PACS system (Picture Archiving and Communication Systems, image archiving and Communication system) data storage as medical image and administrative center, at present application also compare limitation, and application direction also has very extensively Room for promotion.With the establishments of standard such as DICOM3.0, HL7 and the fast development of medical information, large size at home Hospital internal and between all establish the remote medical consultation with specialists center based on PACS, but the remote medical consultation with specialists centrales of international coverage accordingly Preceding or blank so that external advanced medical technology and managerial experiences cannot fast and effectively hospital application at home, project Resource accumulation by the position in industry of declarer and for many years, can be in the exploitation of the remote medical consultation with specialists central platform based on PACS After line, the resource of domestic and international large hospital is quickly integrated, realizes the foundation of international distance Consultation Center, current routine PACS System is often directed to hospital doctor, has ignored disease Man's Demands, can not realize patient and medical treatment, medical staff whenever and wherever possible Exchange and interaction.
Invention content
The embodiment of the present invention is designed to provide a kind of digitized X-ray machine system, it is intended to solve traditional imaging and calculate Method will produce a large amount of artificial artifact, have image detail information loss, not smart enoughization to be not carried out software and hardware in noise reduction process In conjunction with integration, do not have remote medical consultation with specialists function, not specifically for Asian imaging system, patient and doctor cannot be into Row exchange and interactive problem.
The invention is realized in this way a kind of digitized X-ray machine system includes wireless DR (digitalradiography, digitized X-ray machine system) tablet, MINIPACS, image processing software, remote medical consultation with specialists work Flow personalization system, the MINI PACS can be realized both domestic and external as the storage of image, transmission and management system Remote medical consultation with specialists function and tele-medicine function, and provide iphone clients and Andriod clients for mobile device; The image processing software includes full-automatic imaging noise reduction algorithm packet and intelligent picture superposition algorithm packet.
Further, the full-automatic imaging noise reduction algorithm packet includes image analysis module, histogram analysis module, totality Noise prediction module, local CNR prediction modules, mask image computing module, gain calculation module, this is automatically imaged noise reduction calculation Method promotes denoising effect using structural similarity local in whole figure, by the image analysis stage to image high frequency spatial Details and noise maximize and detach, do different optimization processings, detailed process packet for different zones where pixel value It includes:
Original image input, gain-adjusted, Intelligent noise reduction, region cutting, excessive contrast is reduced, detail contrast increases By force, image exports after edge enhancing, the recombination of front and back scape, pictorial element addition, processing.
Further, the intelligent picture superposition algorithm the image analysis stage will have same nature but It spatially separates or continuous region is correctly divided, modified form algorithm of histogram equalization is utilized in image processing process Contrast enhance high efficiency, detailed process includes:
Seed point selection, neighborhood inspection, growth point judgement, the separation of front and back scape, Canny operators edge extracting, Double-histogram Balanced, local auto-adaptive enhancing, image reorganization.
Further, the remote medical consultation with specialists workflow personalization system include to the medical images of DICOM3.0 formats into The GPEG2000 data compression and decompression function module of row processing is passed for different linking Internets and the image of transmission mode Defeated optimization function module, each rank doctor and the authority management module of user, the orderly management module of case diagnosis report, fortune Used in the Medical Language intertranslation database module of transnational remote medical consultation with specialists scene, Work Process Management person's definition module;
The detailed process of the described remote medical consultation with specialists work is:
Step 1: basic hospital obtains patient's image, basic hospital doctor is logged in long-range by doctor's authority management module Consultation system carries out initial diagnosis to image;
Step 2: remote medical consultation with specialists workflow personalization system application GPEG2000 data compression and decompression function modules Medical image file is compressed, the content in report is carried out automatic translation, image by Medical Language intertranslation database module The workflow defined according to administrator is automatically sent to overseas central hospital with report;
Step 3: image transmitting optimization function module will ensure the transmission under different linking Internets and transmission mode at Work(or transmission problem solve guidance;
Step 4: central hospital doctor reads the image obtained and report, further consultation is carried out, Final Report is sent out;
Step 5: the content in report is carried out automatic translation, basic hospital doctor by Medical Language intertranslation database module Obtain last diagnostic report.
Further, described Canny operator intelligences extraction edge the specific steps are:
Step 1: filtering;
Step 2: enhancing, the amplitude using finite difference formulations gradient and direction, gray scale in neighborhood is had significant change Point highlights;
Step 3: detection is divided into determine that edge must retain the maximum point of partial gradient after being quantified according to edge direction Four direction, corresponds to 0, π/4 respectively, pi/2,3 π/4, if center pixel Amplitude Ration is along two adjacent pixels of edge direction Amplitude is big, then is marginal point, otherwise by amplitude clear 0;
Step 4: positioning, in order to accurately determine the position at edge, Canny operators are using dual threshold method and connection Edge, dual threashold value-based algorithm acts on two threshold taus 1 and τ 2, and 2 τ, 1 ≈ τ 2 to non-maxima suppression image, so as to obtain two A threshold skirt image N1 [i, j] and N2 [i, j], algorithm constantly collect edge in N1 [i, j], connect until by N2 [i, j] It picks up until coming.
Further, in order to make intelligent picture superposition algorithm have global bilateral histogram equalization and local detail Improvement type f ' (i, j)=BHE [f (i, j)]+k* [f (i, j)-m (i, j)] can be used in the effect adaptively enhanced, local enhancement;
Further, the MINI PACS follow DICOM3.0 standards, are subtracted by JPEG2000 image Compression technologies Few image transmitting time and the occupancy for reducing memory space realize each application section office whole image data by DICOM servers Digitlization storage with filing management, image nephrite cat's-eye and unbiased LMSE, with no paper operating mode, by HL7 standards It realizes, ensures the seamless connection with HIS/RIS systems.
Further, the MINIPACS combination remote medical consultation with specialists workflow personalization systems are realized not by internet With across the hospital patient data exchange in region, the flow of various remote medical consultation with specialists is completed.
The digitized X-ray machine system of the present invention has concentrated direct digital radiograph, imaging, Image Management, The total solution of storage, transmission, general technical advantage include:
(1) automatically imaging noise reduction algorithm is solving the problems, such as traditional algorithm there may be while artificial artifact, fully Promote denoising effect using local structural similarity in whole figure, by the image analysis stage to image high frequency spatial Details with noise maximize and be detached, and is done different optimization processings for different zones where pixel value, is reached to resolution ratio Maximum retain and the maximum enhancing of image detail contrast.
(2) intelligent picture superposition algorithm can will have same nature in the image analysis stage but spatially divide It opens or connects
Continuous region is correctly divided, and pair of modified form algorithm of histogram equalization is utilized in image processing process Enhance than degree high
Effect property simultaneously, avoids its side effect that may be brought, finally so that image enhancement effects greatly improve, for not Intelligent image enhancement with region can clearly show each detail content, realize " Z-operation " diagnosis of radiologist.
(3) integration of wireless DR tablets realize that the maximization space of x-ray shooting is free;
(4) unlimited extension of the PACS system with remote medical consultation with specialists personalization system to digitlization application range.It realizes long-range Consultation of doctors function.
(5) integration of software and hardware, software algorithm and PACS system and Remote consultation platform are realized, solves conventional DR 3 problems that hardware vendor brings to user:The imaging effect problem brought due to lacking autonomous core imaging algorithm;No The high cost problem that built-in PACS is brought to hospital;Software and hardware compatibility, the problem of safeguarding and upgrade.
Description of the drawings
Fig. 1 is the structural schematic diagram of digitized X-ray machine system provided in an embodiment of the present invention;
Fig. 2 is full-automatic imaging noise reduction algorithm flow chart provided in an embodiment of the present invention;
Fig. 3 is intelligent picture superposition algorithm flow chart provided in an embodiment of the present invention;
Fig. 4 is remote medical consultation with specialists work flow diagram provided in an embodiment of the present invention.
Specific implementation mode
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to Limit the present invention.
Below in conjunction with the accompanying drawings and specific embodiment is further described the application principle of the present invention.
The invention is realized in this way a kind of digitized X-ray machine system includes wireless DR tablets 1, MINIPACS2, figure As processing software 3, remote medical consultation with specialists workflow personalization system 4, the MINIPACS1 as image storage, transmit and Management system can realize remote medical consultation with specialists function and tele-medicine function both domestic and external, and be provided for mobile device Iphone clients and Andriod clients;The image processing software 3 includes full-automatic imaging noise reduction algorithm packet and intelligence Picture superposition algorithm packet can be changed, image processing software is the software kernels part of solution, and signal-to-noise ratio (SNR) is flat 21.6% is improved than traditional imaging algorithm, x-ray dosage reduces by 27.8%.
Further, as shown in Fig. 2, the full-automatic imaging noise reduction algorithm packet includes image analysis module, histogram point Module, global noise prediction module, local CNR prediction modules, mask image computing module, gain calculation module are analysed, this is complete certainly Dynamic imaging noise reduction algorithm promotes denoising effect using structural similarity local in whole figure, by the image analysis stage pair The details of image high frequency spatial with noise maximize and be detached, and the different zones where pixel value are done at different optimization Reason, detailed process include:
Original image input S101, gain-adjusted S102, Intelligent noise reduction S103, region cutting S104, excessive contrast subtract Few S105, detail contrast enhancing S106, edge enhancing S107, front and back scape recombination S108, pictorial element addition S109, processing
Image exports S110 afterwards.
DR images image obtain and transmission process in unavoidably generate noise, cause image resolution ratio and contrast Decline.Traditional, which includes the smooth low pass processing based on domain space such as " gaussian filtering ", to cause image detail information to lose.
It is proposed that a kind of improvement is in the full-automatic imaging noise reduction intelligent algorithm of NL-means, it is possible solving former algorithm While leading to the problem of artificial artifact, local structural similarity in whole figure is made full use of to promote denoising effect, by The image analysis stage with noise maximize and detach to the details of image high frequency spatial, is done for different zones where pixel value Different optimization processings reaches the maximum reservation to resolution ratio and the maximum enhancing of image detail contrast.New algorithm efficiently drops Making an uproar property at the same for realize low-dose X-ray shooting established technical foundation.
Further, the intelligent picture superposition algorithm the image analysis stage will have same nature but It spatially separates or continuous region is correctly divided, modified form algorithm of histogram equalization is utilized in image processing process Contrast enhance high efficiency, as shown in figure 3, detailed process includes:
Seed point selection S201, neighborhood check that S202, growth point judge S203, front and back scape separation S204, Canny operator side Edge extracts S2051, Double-histogram equilibrium S2052, local auto-adaptive enhancing S2053, image reorganization S206.
Finally so that image enhancement effects greatly improve, can clearly be shown for the intelligent image enhancement of different zones Each detail content realizes " Z-operation " diagnosis of radiologist.
Further, the remote medical consultation with specialists workflow personalization system include to the medical images of DICOM3.0 formats into The GPEG2000 data compression and decompression function module of row processing is passed for different linking Internets and the image of transmission mode Defeated optimization function module, each rank doctor and the authority management module of user, the orderly management module of case diagnosis report, fortune Used in the Medical Language intertranslation database module of transnational remote medical consultation with specialists scene, Work Process Management person's definition module;Such as Fig. 4 institutes Show, the detailed process of remote medical consultation with specialists work is:
Step 1: basic hospital obtains patient's image, basic hospital doctor is logged in long-range by doctor's authority management module Consultation system carries out initial diagnosis to image;
Step 2: remote medical consultation with specialists workflow personalization system application GPEG2000 data compression and decompression function modules Medical image file is compressed, the content in report is carried out automatic translation, image by Medical Language intertranslation database module The workflow defined according to administrator is automatically sent to overseas central hospital with report;
Step 3: image transmitting optimization function module will ensure the transmission under different linking Internets and transmission mode at Work(or transmission problem solve guidance;
Step 4: central hospital doctor reads the image obtained and report, further consultation is carried out, Final Report is sent out;
Step 5: the content in report is carried out automatic translation, basic hospital doctor by Medical Language intertranslation database module Obtain last diagnostic report.
Further, described Canny operator intelligences extraction edge the specific steps are:
Step 1: filtering;
Step 2: enhancing, the amplitude using finite difference formulations gradient and direction, gray scale in neighborhood is had significant change Point highlights;
Step 3: detection inhibits the operation direction of non-maximum to determine that edge must retain the maximum point of partial gradient As shown in table 1, it is divided into four direction after quantifying according to edge direction, corresponds to 0, π/4, pi/2,3 π/4, if center pixel respectively Amplitude Ration is big along the amplitude of two adjacent pixels of edge direction, then is marginal point, otherwise by amplitude clear 0;
Table 1
3π/4 π/2 π/4
0 Center pixel 0
π/4 π/2 3π/4
Step 4: positioning, in order to accurately determine the position at edge, Canny operators are using dual threshold method and connection Edge, dual threashold value-based algorithm acts on two threshold taus 1 and τ 2, and 2 τ, 1 ≈ τ 2 to non-maxima suppression image, so as to obtain two A threshold skirt image N1 [i, j] and N2 [i, j], algorithm constantly collect edge in N1 [i, j], connect until by N2 [i, j] It picks up until coming.
Further, in order to make intelligent picture superposition algorithm have global bilateral histogram equalization and local detail Improvement type f ' (i, j)=BHE [f (i, j)]+k* [f (i, j)-m (i, j)] can be used in the effect adaptively enhanced, local enhancement, BHE [f (i, j)] indicates that, to original image pixel grey scale progress gray scale Double-histogram equalization, f ' (i, j) is equal by the gray level of macroscopic view It weighs and the details of part enhances two parts adduction, had both the good characteristic of two methods, be a kind of intelligent local auto-adaptive increasing Strong algorithms.Canny operators have more advantages as the advanced operator of edge extracting compared with other operators, such as edge continuity is more It is good, positioning is more acurrate etc., it is important to anti-noise ability is stronger.
Further, the MINIPACS follows DICOM3.0 standards, is subtracted by JPEG2000 image Compression technologies Few image transmitting time and the occupancy for reducing memory space realize each application section office whole image data by DICOM servers Digitlization storage with filing management, image nephrite cat's-eye and unbiased LMSE, with no paper operating mode, by HL7 standards It realizes, ensures the seamless connection with HIS/RIS systems.
Further, the MINI PACS combination remote medical consultation with specialists workflow personalization systems are realized not by internet With across the hospital patient data exchange in region, the flow of various remote medical consultation with specialists is completed.
The digitized X-ray machine system of the present invention has concentrated direct digital radiograph, imaging, Image Management, The total solution of storage, transmission, general technical advantage include:
(1) automatically imaging noise reduction algorithm is solving the problems, such as traditional algorithm there may be while artificial artifact, fully Promote denoising effect using local structural similarity in whole figure, by the image analysis stage to image high frequency spatial Details with noise maximize and be detached, and is done different optimization processings for different zones where pixel value, is reached to resolution ratio Maximum retain and the maximum enhancing of image detail contrast.
(2) intelligent picture superposition algorithm can will have same nature in the image analysis stage but spatially divide It opens or continuous region is correctly divided, the comparison of modified form algorithm of histogram equalization is utilized in image processing process Degree enhancing high efficiency simultaneously, avoids its side effect that may be brought, finally so that image enhancement effects greatly improve, for not Intelligent image enhancement with region can clearly show each detail content, realize " Z-operation " diagnosis of radiologist.
(3) integration of wireless DR tablets realize that the maximization space of x-ray shooting is free;
(4) unlimited extension of the PACS system with remote medical consultation with specialists personalization system to digitlization application range.It realizes long-range Consultation of doctors function.
(5) integration of software and hardware, software algorithm and PACS system and Remote consultation platform are realized, solves conventional DR 3 problems that hardware vendor brings to user:The imaging effect problem brought due to lacking autonomous core imaging algorithm;No The high cost problem that built-in PACS is brought to hospital;Software and hardware compatibility, the problem of safeguarding and upgrade.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention All any modification, equivalent and improvement etc., should all be included in the protection scope of the present invention made by within refreshing and principle.

Claims (3)

1. a kind of digitized X-ray machine system, which is characterized in that the digitized X-ray machine system include wireless DR tablets, MINI PACS, image processing software, remote medical consultation with specialists workflow personalization system, MINI PACS the depositing as image Storage, transmission and management system, can realize remote medical consultation with specialists function and tele-medicine function both domestic and external, and be directed to mobile device Iphone clients and Andriod clients are provided;The image processing software include full-automatic imaging noise reduction algorithm packet and Intelligent picture superposition algorithm packet;
The full-automatic imaging noise reduction algorithm packet includes image analysis module, histogram analysis module, global noise prediction mould Block, local CNR prediction modules, mask image computing module, gain calculation module, this is automatically imaged noise reduction algorithm using entirety Local structural similarity promotes denoising effect in figure, by the image analysis stage to the details of image high frequency spatial with make an uproar Sound carries out maximization separation, does different optimization processings for different zones where pixel value, detailed process includes:
Original image input, gain-adjusted, Intelligent noise reduction, region cutting, excessive contrast is reduced, detail contrast enhances, side Image exports after edge enhancing, the recombination of front and back scape, pictorial element addition, processing;
The intelligent picture superposition algorithm will have same nature but spatially separated in the image analysis stage Or continuous region is correctly divided, and is increased using the contrast of modified form algorithm of histogram equalization in image processing process Strong high efficiency, detailed process include:
Seed point selection, neighborhood inspection, growth point judgement, the separation of front and back scape, Canny operators edge extracting, Double-histogram be balanced, Local auto-adaptive enhancing, image reorganization.
2. digitized X-ray machine system as described in claim 1, which is characterized in that the remote medical consultation with specialists workflow Property system includes the GPEG2000 data compression and decompression function moulds handled the medical image of DICOM3.0 formats Block optimizes function module, the permission of each rank doctor and user for different linking Internets and the image transmitting of transmission mode Management module, the orderly management module of case diagnosis report, the Medical Language intertranslation number for being used in transnational remote medical consultation with specialists scene According to library module, Work Process Management person's definition module;
The detailed process of the described remote medical consultation with specialists work is:
Step 1: basic hospital obtains patient's image, basic hospital doctor logs in remote medical consultation with specialists by doctor's authority management module Workflow personalization system carries out initial diagnosis to image;
Step 2: remote medical consultation with specialists workflow personalization system application GPEG2000 data compression and decompression function module will be cured It learns image file to be compressed, the content in report is carried out automatic translation, image and report by Medical Language intertranslation database module The workflow defined according to administrator is automatically sent to overseas central hospital by announcement;
Step 3: image transmitting optimization function module will ensure the transmission success under different linking Internets and transmission mode or Transmission problem solves guidance;
Step 4: central hospital doctor reads the image obtained and report, further consultation is carried out, Final Report is sent out;
Step 5: the content in report is carried out automatic translation by Medical Language intertranslation database module, basic hospital doctor obtains Last diagnostic is reported.
3. digitized X-ray machine system as described in claim 1, which is characterized in that the Canny operator intelligences extraction Edge the specific steps are:
Step 1: filtering;
Step 2: enhancing, the amplitude using finite difference formulations gradient and direction, the point that gray scale in neighborhood has significant change is dashed forward Go out display;
Step 3: detection is divided into four to determine that edge must retain the maximum point of partial gradient after quantifying according to edge direction A direction corresponds to 0, π/4, pi/2,3 π/4, if center pixel Amplitude Ration is along the amplitude of two adjacent pixels of edge direction respectively Greatly, then it is marginal point, otherwise by amplitude clear 0;
Step 4: positioning, in order to accurately determine the position at edge, Canny operators are using dual threshold method and connect edge, Dual threashold value-based algorithm acts on two threshold taus 1 and τ 2, and 2 τ, 1 ≈ τ 2 to non-maxima suppression image, so as to obtain two threshold values Edge image N1 [i, j] and N2 [i, j], algorithm are constantly collected edge in N1 [i, j], are connected until by N2 [i, j] Until;
Further, in order to make, intelligent picture superposition algorithm has global bilateral histogram equalization and local detail is adaptive Improvement type f ' (i, j)=BHE [f (i, j)]+k* [f (i, j)-m (i, j)], BHE [f can be used in the effect that should enhance, local enhancement (i, j)] indicate to original image pixel grey scale carry out gray scale Double-histogram equalization, f ' (i, j) by macroscopic view gray level equilibrium and The details of part enhances two parts adduction;
Further, the MINI PACS follow DICOM3.0 standards, are reduced and are schemed by JPEG2000 image Compression technologies As transmission time and the occupancy of reduction memory space, each number using section office's whole image data is realized by DICOM servers Word storage and filing management, image nephrite cat's-eye and unbiased LMSE, with no paper operating mode, by the realization to HL7 standards, Ensure the seamless connection with HIS/RIS systems;
The MINI PACS combination remote medical consultation with specialists workflow personalization systems, by internet realize different zones across Hospital patient data exchange completes the flow of various remote medical consultation with specialists.
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