CN104574316A - Digital X-ray imaging system - Google Patents

Digital X-ray imaging system Download PDF

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CN104574316A
CN104574316A CN201510014273.6A CN201510014273A CN104574316A CN 104574316 A CN104574316 A CN 104574316A CN 201510014273 A CN201510014273 A CN 201510014273A CN 104574316 A CN104574316 A CN 104574316A
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CN104574316B (en
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钱宇
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NANJING BAINENGWEI MEDICAL TECHNOLOGY Co Ltd
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Abstract

The invention discloses a digital X-ray imaging system. The system comprises a wireless DR panel, a MINI PACS, image processing software and a remote consultation working process personalization system, wherein the MINI PACS serves as the image storing, transmitting and managing system and is capable of achieving domestic and abroad remote consultation and telemedicine, and the image processing software comprises a fully-automatic imaging denoising algorithm package and an intelligent image contrast enhancing algorithm package. According to the system, direct digital radiograph, image processing and image management, storage and transmission are integrated, resolution ratio is reserved to the maximum and image detail contrast is enhanced to the maximum by means of the fully-automatic imaging denoising algorithm, intelligent images in different areas are enhanced by means of the intelligent image contrast enhancing algorithm so that the content of each detail can be displayed clearly, zero-operation diagnosis of a radiologist is achieved, remote consultation is achieved through the PACS, and software and hardware integration is achieved.

Description

A kind of digitized X-ray machine system
Technical field
The invention belongs to medical imaging field, particularly relate to a kind of digitized X-ray machine system.
Background technology
The medical imaging Processing Algorithm of traditional imaging algorithm realize on decrease of noise functions utilize as Laplacian pyramid spatially frequency layering be Fourier and change, this type of algorithm can produce a large amount of artificial artifacts, also irreversiblely in noise reduction process removes some important picture material and details.
It is abroad the imaging algorithm of the digital medical image documentation equipment raw manufacturer majority use independent development of representative with Agfa, MUSICA2 as Agfa have employed multiband image enhancement processing technology, spatially piece image is split into 12 different levels (frequency) by the height etc. of frequency, according to different applications, respectively enhancing in various degree, suppression, contrast, the adjustment of window width and window level, the enhancing at edge and treatment of details are carried out to each frequency range.The common many utilizations of medical imaging Processing Algorithm as Laplacian pyramid spatially frequency layering be Fourier change, the high-frequency region concentrated details and noise carries out denoising and details strengthens, low frequency region carries out retaining or slightly processing, then inversefouriertransform slice.The method is not intelligent, inevitably removes details when process high frequency noise.Most of manufacturer, due to the restriction of technology and fund, have purchased with the core of the U.S. Context Vision third party's image processing algorithms that is representative as imaging software.Although such combination can form complete imaging system in a short time, but due to hardware and design difference, the reasons such as experimental data is limited, Processing Algorithm can only carry out limited image procossing when passive acquisition data, final imaging effect is difficult to obtain optimum efficiency.Comprise GE, Carestream medical treatment is interior medical giant, and due to medical treatment, educational resource and the traditional factor of scientific research, the phenomenon that research and development product and characteristic Occidentalize is serious.Product is rarer for the clinical of asian population or experiment.Asian population and American-European crowd are in fitness, and body structure, body shape has generally to be distinguished, and the setting from the recommended value of film making parameter to Image Processing parameter has error.
Traditional PACS system (Picture Archiving and Communication Systems, image archiving and communication system) as the data storing of medical image and administrative center, current application also compares limitation, and application direction also has very wide room for promotion.Along with DICOM3.0, the fast development of the establishments of standard such as HL7 and medical information, large hospital at home inner and between establish remote medical consultation with specialists center based on PACS all accordingly, but the remote medical consultation with specialists centrales of international coverage is front or blank, make external advanced medical skill and managerial experience can not be quick, effective hospital application at home, project is by the position in industry of declarer and resource accumulation for many years, after can reaching the standard grade in the remote medical consultation with specialists central platform exploitation based on PACS, integrate the resource of domestic and international large hospital fast, realize the foundation of international distance Consultation Center, current conventional PACS system is often for hospital doctor, have ignored disease Man's Demands, patient and medical treatment can not be realized, medical personnel are mutual exchange and effect anywhere or anytime.
Summary of the invention
The object of the embodiment of the present invention is to provide a kind of digitized X-ray machine system, be intended to solve traditional imaging algorithm and can produce a large amount of artificial artifacts, image detail information is had to lose in noise reduction process, intelligent not, do not realize the integration of software and hardware combining, do not have remote medical consultation with specialists function, do not have special in Asian imaging system, patient and doctor can not carry out the problem of mutual exchange and effect.
The present invention realizes like this, a kind of digitized X-ray machine system comprises wireless DR (digital radiography, digitized X-ray machine system) flat board, MINI PACS, image processing software, remote medical consultation with specialists workflow personalization system, described MINI PACS as image storage, transmission administrating system, remote medical consultation with specialists function both domestic and external and tele-medicine function can be realized, and provide iphone client and Andriod client for mobile device; Described image processing software includes full-automatic imaging noise reduction algorithm bag and intelligent picture superposition algorithm bag.
Further, described full-automatic imaging noise reduction algorithm handbag draws together image analysis module, histogram analysis module, global noise prediction module, local CNR prediction module, mask image computing module, gain calculation module, this full-automatic imaging noise reduction algorithm utilizes the structural similarity of local in overall figure to promote denoising effect, be separated by carrying out maximization in the graphical analysis stage to the details of image high frequency spatial and noise, do different optimization processes for pixel value place zones of different, idiographic flow comprises:
Original image input, gain-adjusted, Intelligent noise reduction, region cutting, excessive contrast minimizing, detail contrast enhancing, edge enhancing, the restructuring of front and back scape, pictorial element add, process rear image output.
Further, described intelligent picture superposition algorithm the graphical analysis stage will have same nature but spatially separately or continuous print region correctly divide, in image processing process, utilize the contrast strengthen high efficiency of modified form algorithm of histogram equalization, idiographic flow comprises:
Seed Points selection, neighborhood inspection, growth point judgement, the separation of front and back scape, the equilibrium of Canny operator edge extracting, Double-histogram, local auto-adaptive enhancing, image reorganization.
Further, described remote medical consultation with specialists workflow personalization system comprise the medical image of DICOM3.0 form is processed GPEG2000 data compression and decompression functional module, the image transmitting optimizational function module for different linking Internet and transmission mode, the authority management module of each rank doctor and user, case diagnosis report orderly management module, be used in Medical Language intertranslation database module, Work Process Management person's definition module of transnational remote medical consultation with specialists scene;
The idiographic flow of described remote medical consultation with specialists work is:
Step one, basic hospital obtain patient's image, and basic hospital doctor logs in Tele-consultation System by doctor's authority management module, carries out ID to image;
Medical image file compresses by step 2, remote medical consultation with specialists workflow personalization system application GPEG2000 data compression and decompression functional module, content in report is carried out automatic translation by Medical Language intertranslation database module, and the workflow defined according to keeper is sent to overseas central hospital by image and report automatically;
The transmission success ensured under different linking Internet and transmission mode or transmission problem solve and instruct by step 3, image transmitting optimizational function module;
Step 4, central hospital doctor read image and the report of acquisition, carry out further consultation, are sent by final report;
Content in report is carried out automatic translation by step 5, Medical Language intertranslation database module, and basic hospital doctor obtains last diagnostic report.
Further, the concrete steps that edge is extracted in described Canny operator intellectuality are:
Step one, filtering;
Step 2, enhancing, adopt amplitude and the direction of finite difference formulations gradient, some gray scale in neighborhood had significant change highlights;
Step 3, detection, for determining that edge must retain the maximum point of partial gradient, four direction is divide into after quantizing according to edge direction, corresponding 0, π/4 respectively, pi/2, π/4, if center pixel Amplitude Ration is large along the amplitude of two adjacent pixels of edge direction, be then marginal point, otherwise by clear for amplitude 0;
Step 4, location, in order to accurately determine the position at edge, what Canny operator adopted is dual threshold method and be connected edge., dual threshold algorithm is to non-maxima suppression image effect two threshold tau 1 and τ 2, and 2 τ 1 ≈ τ 2, thus two threshold skirt image N1 [i, j] and N2 [i, j] can be obtained, algorithm is constantly at N1 [i, j] middle collection edge, until till N2 [i, j] is coupled together.
Further, in order to the effect making intelligent picture superposition algorithm possess overall bilateral histogram equalization and the enhancing of local detail self-adaptation, local enhancement can adopt improvement type f ' (i, j)=BHE [f (i, j)]+k* [f (i, j)-m (i, j)]
Further, described MINI PACS follows DICOM3.0 standard, reduce the image transmitting time by JPEG2000 image Compression technology and reduce taking of storage space, the digitizing storage of each application section office whole image data and filing management, image nephrite cat's-eye and unbiased LMSE, with no paper operating mode is realized by DIOCOM server, by the realization to HL7 standard, ensure the seamless link with HIS/RIS system.
Further, described MINI PACS in conjunction with remote medical consultation with specialists workflow personalization system, by internet realize zones of different across hospital patient data exchange, complete the flow process of various remote medical consultation with specialists.
Digitized X-ray machine system of the present invention has concentrated direct digital radiograph, imaging processing, the total solution of Image Management, storage, transmission, and its general technical advantage comprises:
(1) full-automatic imaging noise reduction algorithm is solving while traditional algorithm may produce artificial artifact problem, the structural similarity making full use of local in overall figure promotes denoising effect, be separated by carrying out maximization in the graphical analysis stage to the details of image high frequency spatial and noise, do different optimization processes for pixel value place zones of different, reach the maximum enhancing of maximum reservation to resolution and image detail contrast.
(2) intelligent picture superposition algorithm the graphical analysis stage can will have same nature but spatially separately or continuous print region correctly divide, the contrast strengthen high efficiency of modified form algorithm of histogram equalization is make use of simultaneously in image processing process, avoid the spinoff that it may bring, image enhancement effects is finally made greatly to improve, intelligent image enhaucament for zones of different can each detail content of clear display, realizes " Z-operation " diagnosis of radiologist.
(3) integration of wireless DR flat board realizes the maximization space free of x-ray shooting;
(4) PACS system and remote medical consultation with specialists personalization system are to the unlimited extension of digitizing range of application.Achieve remote medical consultation with specialists function.
(5) achieve the integration of software and hardware, software algorithm and PACS system and Remote consultation platform, solve 3 problems that conventional DR hardware vendor brings to user: owing to lacking the imaging effect problem that autonomous core imaging algorithm brings; There is no the high cost problem that built-in PACS brings to hospital; Software and hardware is compatible, the problem safeguarded and upgrade.
Accompanying drawing explanation
Fig. 1 is the structural representation of the digitized X-ray machine system that the embodiment of the present invention provides;
Fig. 2 is the full-automatic imaging noise reduction algorithm process flow diagram that the embodiment of the present invention provides;
Fig. 3 is the intelligent picture superposition algorithm flow chart that the embodiment of the present invention provides;
Fig. 4 is the remote medical consultation with specialists workflow diagram that the embodiment of the present invention provides.
Embodiment
In order to make object of the present invention, technical scheme and advantage clearly understand, below in conjunction with embodiment, the present invention is further elaborated.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.
Below in conjunction with drawings and the specific embodiments, application principle of the present invention is further described.
The present invention realizes like this, a kind of digitized X-ray machine system comprises wireless DR flat board 1, MINI PACS2, image processing software 3, remote medical consultation with specialists workflow personalization system 4, described MINI PACS1 as image storage, transmission administrating system, remote medical consultation with specialists function both domestic and external and tele-medicine function can be realized, and provide iphone client and Andriod client for mobile device; Described image processing software 3 includes full-automatic imaging noise reduction algorithm bag and intelligent picture superposition algorithm bag, image processing software is the software kernels part of solution, its signal to noise ratio (snr) average specific tradition imaging algorithm improves 21.6%, and x-ray dosage reduces by 27.8%.
Further, as shown in Figure 2, described full-automatic imaging noise reduction algorithm handbag draws together image analysis module, histogram analysis module, global noise prediction module, local CNR prediction module, mask image computing module, gain calculation module, this full-automatic imaging noise reduction algorithm utilizes the structural similarity of local in overall figure to promote denoising effect, be separated by carrying out maximization in the graphical analysis stage to the details of image high frequency spatial and noise, do different optimization processes for pixel value place zones of different, idiographic flow comprises:
Original image input S101, gain-adjusted S102, Intelligent noise reduction S103, region cutting S104, excessive contrast minimizing S105, detail contrast enhancing S106, edge enhancing S107, front and back scape restructuring S108, pictorial element add S109, process rear image output S110.
DR image unavoidably produces noise in Image Acquisition and transmitting procedure, causes the decline of image resolution ratio and contrast.Traditional comprise " gaussian filtering " etc. can cause image detail information to lose based on the level and smooth low pass process of domain space.We propose a kind of full-automatic imaging noise reduction intelligent algorithm improved in NL-means, former algorithm solving while may produce artificial artifact problem, the structural similarity making full use of local in overall figure promotes denoising effect, be separated by carrying out maximization in the graphical analysis stage to the details of image high frequency spatial and noise, do different optimization processes for pixel value place zones of different, reach the maximum enhancing of maximum reservation to resolution and image detail contrast.New algorithm high-efficient noise-reducing has established technical foundation for realizing low-dose X-ray shooting simultaneously.
Further, described intelligent picture superposition algorithm the graphical analysis stage will have same nature but spatially separately or continuous print region correctly divide, the contrast strengthen high efficiency of modified form algorithm of histogram equalization is utilized in image processing process, as shown in Figure 3, idiographic flow comprises:
Seed Points selects S201, neighborhood inspection S202, growth point judges that S203, front and back scape are separated S204, Canny operator edge extracting S2051, the balanced S2052 of Double-histogram, local auto-adaptive strengthens S2053, image reorganization S206.
Finally make image enhancement effects greatly improve, the intelligent image enhaucament for zones of different can each detail content of clear display, realizes " Z-operation " diagnosis of radiologist.
Further, described remote medical consultation with specialists workflow personalization system comprise the medical image of DICOM3.0 form is processed GPEG2000 data compression and decompression functional module, the image transmitting optimizational function module for different linking Internet and transmission mode, the authority management module of each rank doctor and user, case diagnosis report orderly management module, be used in Medical Language intertranslation database module, Work Process Management person's definition module of transnational remote medical consultation with specialists scene; As shown in Figure 4, the idiographic flow of described remote medical consultation with specialists work is:
Step one, basic hospital obtain patient's image, and basic hospital doctor logs in Tele-consultation System by doctor's authority management module, carries out ID to image;
Medical image file compresses by step 2, remote medical consultation with specialists workflow personalization system application GPEG2000 data compression and decompression functional module, content in report is carried out automatic translation by Medical Language intertranslation database module, and the workflow defined according to keeper is sent to overseas central hospital by image and report automatically;
The transmission success ensured under different linking Internet and transmission mode or transmission problem solve and instruct by step 3, image transmitting optimizational function module;
Step 4, central hospital doctor read image and the report of acquisition, carry out further consultation, are sent by final report;
Content in report is carried out automatic translation by step 5, Medical Language intertranslation database module, and basic hospital doctor obtains last diagnostic report.
Further, the concrete steps that edge is extracted in described Canny operator intellectuality are:
Step one, filtering;
Step 2, enhancing, adopt amplitude and the direction of finite difference formulations gradient, some gray scale in neighborhood had significant change highlights;
Step 3, detection, for determining that edge must retain the maximum point of partial gradient, suppress the direction of operating of non-maximum value as shown in table 1, divide into four direction after quantizing according to edge direction, respectively correspondence 0, π/4, pi/2, π/4, if center pixel Amplitude Ration is large along the amplitude of two adjacent pixels of edge direction, be then marginal point, otherwise by clear for amplitude 0;
Table 1
/ 4 π / 2 π / 4
0 Center pixel 0
π / 4 π / 2 / 4
Step 4, location, in order to accurately determine the position at edge, what Canny operator adopted is dual threshold method and be connected edge., dual threshold algorithm is to non-maxima suppression image effect two threshold tau 1 and τ 2, and 2 τ 1 ≈ τ 2, thus two threshold skirt image N1 [i, j] and N2 [i, j] can be obtained, algorithm is constantly at N1 [i, j] middle collection edge, until till N2 [i, j] is coupled together.
Further, in order to the effect making intelligent picture superposition algorithm possess overall bilateral histogram equalization and the enhancing of local detail self-adaptation, local enhancement can adopt improvement type f ' (i, j)=BHE [f (i, j)]+k* [f (i, j)-m (i, j)]
BHE [f (i, j)] expression carries out gray scale Double-histogram equalization to original image pixel grey scale. f ' (i, j) details that is balanced by the gray level of macroscopic view and local strengthen two parts add and, having had the good characteristic of two kinds of methods concurrently, is that a kind of intelligent local auto-adaptive strengthens algorithm.Canny operator has more advantages as the senior operator of edge extracting compared with other operators, and such as edge continuity is better, and it is more accurate etc. to locate, and key is that anti-noise ability is stronger.
Further, described MINI PACS follows DICOM3.0 standard, reduce the image transmitting time by JPEG2000 image Compression technology and reduce taking of storage space, the digitizing storage of each application section office whole image data and filing management, image nephrite cat's-eye and unbiased LMSE, with no paper operating mode is realized by DIOCOM server, by the realization to HL7 standard, ensure the seamless link with HIS/RIS system.
Further, described MINI PACS in conjunction with remote medical consultation with specialists workflow personalization system, by internet realize zones of different across hospital patient data exchange, complete the flow process of various remote medical consultation with specialists.
Digitized X-ray machine system of the present invention has concentrated direct digital radiograph, imaging processing, the total solution of Image Management, storage, transmission, and its general technical advantage comprises:
(1) full-automatic imaging noise reduction algorithm is solving while traditional algorithm may produce artificial artifact problem, the structural similarity making full use of local in overall figure promotes denoising effect, be separated by carrying out maximization in the graphical analysis stage to the details of image high frequency spatial and noise, do different optimization processes for pixel value place zones of different, reach the maximum enhancing of maximum reservation to resolution and image detail contrast.
(2) intelligent picture superposition algorithm the graphical analysis stage can will have same nature but spatially separately or continuous print region correctly divide, the contrast strengthen high efficiency of modified form algorithm of histogram equalization is make use of simultaneously in image processing process, avoid the spinoff that it may bring, image enhancement effects is finally made greatly to improve, intelligent image enhaucament for zones of different can each detail content of clear display, realizes " Z-operation " diagnosis of radiologist.
(3) integration of wireless DR flat board realizes the maximization space free of x-ray shooting;
(4) PACS system and remote medical consultation with specialists personalization system are to the unlimited extension of digitizing range of application.Achieve remote medical consultation with specialists function.
(5) achieve the integration of software and hardware, software algorithm and PACS system and Remote consultation platform, solve 3 problems that conventional DR hardware vendor brings to user: owing to lacking the imaging effect problem that autonomous core imaging algorithm brings; There is no the high cost problem that built-in PACS brings to hospital; Software and hardware is compatible, the problem safeguarded and upgrade.
The foregoing is only preferred embodiment of the present invention, not in order to limit the present invention, all any amendments done within the spirit and principles in the present invention, equivalent replacement and improvement etc., all should be included within protection scope of the present invention.

Claims (6)

1. a digitized X-ray machine system, it is characterized in that, described digitized X-ray machine system comprises wireless DR flat board, MINI PACS, image processing software, remote medical consultation with specialists workflow personalization system, described MINI PACS as image storage, transmission administrating system, remote medical consultation with specialists function both domestic and external and tele-medicine function can be realized, and provide iphone client and Andriod client for mobile device; Described image processing software comprises full-automatic imaging noise reduction algorithm bag and intelligent picture superposition algorithm bag.
2. digitized X-ray machine system as claimed in claim 1, it is characterized in that, image analysis module drawn together by described full-automatic imaging noise reduction algorithm handbag, histogram analysis module, global noise prediction module, local CNR prediction module, mask image computing module, gain calculation module, this full-automatic imaging noise reduction algorithm utilizes the structural similarity of local in overall figure to promote denoising effect, be separated by carrying out maximization in the graphical analysis stage to the details of image high frequency spatial and noise, different optimization processes is done for pixel value place zones of different, idiographic flow comprises:
Original image input, gain-adjusted, Intelligent noise reduction, region cutting, excessive contrast minimizing, detail contrast enhancing, edge enhancing, the restructuring of front and back scape, pictorial element add, process rear image output.
3. digitized X-ray machine system as claimed in claim 1, it is characterized in that, described intelligent picture superposition algorithm the graphical analysis stage will have same nature but spatially separately or continuous print region correctly divide, in image processing process, utilize the contrast strengthen high efficiency of modified form algorithm of histogram equalization, idiographic flow comprises:
Seed Points selection, neighborhood inspection, growth point judgement, the separation of front and back scape, the equilibrium of Canny operator edge extracting, Double-histogram, local auto-adaptive enhancing, image reorganization.
4. digitized X-ray machine system as claimed in claim 1, it is characterized in that, described remote medical consultation with specialists workflow personalization system comprise the medical image of DICOM3.0 form is processed GPEG2000 data compression and decompression functional module, the image transmitting optimizational function module for different linking Internet and transmission mode, the authority management module of each rank doctor and user, case diagnosis report orderly management module, be used in Medical Language intertranslation database module, Work Process Management person's definition module of transnational remote medical consultation with specialists scene;
The idiographic flow of described remote medical consultation with specialists work is:
Step one, basic hospital obtain patient's image, and basic hospital doctor logs in Tele-consultation System by doctor's authority management module, carries out ID to image;
Medical image file compresses by step 2, remote medical consultation with specialists workflow personalization system application GPEG2000 data compression and decompression functional module, content in report is carried out automatic translation by Medical Language intertranslation database module, and the workflow defined according to keeper is sent to overseas central hospital by image and report automatically;
The transmission success ensured under different linking Internet and transmission mode or transmission problem solve and instruct by step 3, image transmitting optimizational function module;
Step 4, central hospital doctor read image and the report of acquisition, carry out further consultation, are sent by final report;
Content in report is carried out automatic translation by step 5, Medical Language intertranslation database module, and basic hospital doctor obtains last diagnostic report.
5. digitized X-ray machine system as claimed in claim 1, is characterized in that, the concrete steps that edge is extracted in described Canny operator intellectuality are:
Step one, filtering;
Step 2, enhancing, adopt amplitude and the direction of finite difference formulations gradient, some gray scale in neighborhood had significant change highlights;
Step 3, detection, for determining that edge must retain the maximum point of partial gradient, four direction is divide into after quantizing according to edge direction, corresponding 0, π/4 respectively, pi/2, π/4, if center pixel Amplitude Ration is large along the amplitude of two adjacent pixels of edge direction, be then marginal point, otherwise by clear for amplitude 0;
Step 4, location, in order to accurately determine the position at edge, what Canny operator adopted is dual threshold method and be connected edge., dual threshold algorithm is to non-maxima suppression image effect two threshold tau 1 and τ 2, and 2 τ 1 ≈ τ 2, thus two threshold skirt image N1 [i, j] and N2 [i, j] can be obtained, algorithm is constantly at N1 [i, j] middle collection edge, until till N2 [i, j] is coupled together.
6. further, in order to the effect making intelligent picture superposition algorithm possess overall bilateral histogram equalization and the enhancing of local detail self-adaptation, local enhancement can adopt improvement type f ' (i, j)=BHE [f (i, j)]+k* [f (i, j)-m (i, j)];
Further, described MINI PACS follows DICOM3.0 standard, reduce the image transmitting time by JPEG2000 image Compression technology and reduce taking of storage space, the digitizing storage of each application section office whole image data and filing management, image nephrite cat's-eye and unbiased LMSE, with no paper operating mode is realized by DIOCOM server, by the realization to HL7 standard, ensure the seamless link with HIS/RIS system;
Digitized X-ray machine system as claimed in claim 1, it is characterized in that, described MINI PACS in conjunction with remote medical consultation with specialists workflow personalization system, by internet realize zones of different across hospital patient data exchange, complete the flow process of various remote medical consultation with specialists.
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