CN1045527C - Paeonol health cigarette and production thereof - Google Patents
Paeonol health cigarette and production thereof Download PDFInfo
- Publication number
- CN1045527C CN1045527C CN 96108385 CN96108385A CN1045527C CN 1045527 C CN1045527 C CN 1045527C CN 96108385 CN96108385 CN 96108385 CN 96108385 A CN96108385 A CN 96108385A CN 1045527 C CN1045527 C CN 1045527C
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- CN
- China
- Prior art keywords
- paeonol
- peonol
- cigarette
- health care
- pipe tobacco
- Prior art date
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- Expired - Fee Related
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- Medicines Containing Plant Substances (AREA)
Abstract
The present invention discloses a health care cigarette of paeonol, and a manufacture method thereof. The manufacture method is characterized in that paeonol is prepared from medical parts of six traditional Chinese medicines such as peony park, etc. by using a steam distillation method and an artificial chemical synthesis method, composite paeonol exaction substances containing the paeonol are extracted by using a grain alcohol percolation method, and the paeonol and tobacco shreds are uniformly mixed proportionally by using a direct addition method and a displacement method of super critical extraction and are coiled and packed by a machine to prepare the health care cigarette of paeonol. The health care cigarette of paeonol uses abundant traditional Chinese herbal medicine resources, and the extracted peonol is used to prepare a health care cigarette to benefit heart and blood vessels of a smoker and a passive smoker and to prevent cancers. Harmful ingredients displaced in super critical extraction of the tobacco shreds can be purified into important materials of medical chemical industry.
Description
The present invention relates to the preparation method in cigarette industry field, particularly paeonol health cigarette.It is to form by mixing to roll with pipe tobacco from the medicinal extracting section of Chinese herbal medicine or artificial synthetic peonol.
As everyone knows, Smoking is harmful to your health, contaminated environment, has been people's common recognition.In the face of China several hundred million smokers, become worthy of the name global No.1 smoking big country, how to solve the contradiction of " smoking is with healthy ", the measure of Tobacco Control is worldwide proposed, The World Health Organization (WHO) proposes 1995-1999 " tobacco and healthy action plan ", and the Chinese government has also done corresponding Tobacco Control and promised to undertake.At present the world all in research, find out the way of the contradiction of solutions " smoking and health ".
The object of the present invention is to provide a kind of preparation method of paeonol health cigarette.The prepared cigarette of the present invention had both been satisfied smoker's needs, made smoker and involuntary smoker reduce murder by poisoning again, solved the contradiction of " smoking is with healthy " preferably.
The objective of the invention is to realize as follows:
One, the raw material of peonol and preparation
1. peonol has another name called Paeonol, paeonol, be the active ingredient of extracting from multiple Chinese herbal medicine, as: moutan bark (CORTEXMOUTAN), paniculate swallowwort (pycnostel Ma paniculatum Bunge K.schum) herb, white birch (Betula platy-phylla suk Var japonica sieb Hera) bark, auricula (Primula auricub L.) herb, alizarin (the Buthysa meridionalis L.B.Smity﹠amp of Brazil; Downs) root, and the medicinal part of Chinese medicinal herbs such as Dian clove (Luculia intermedia Hutch) complete stool all contains peonol.
2. with six kinds of above-mentioned moutan bark, paniculate swallowwort, white birch, auricula, Brazilian madder and Dian cloves etc. or one or more Chinese medicinal herbses wherein, break into fine powder, make the crude product of peonol with steam distillation, promptly get pure peonol through the ethyl alcohol recrystallization method is refining again;
3. also the peonol of available artificial chemical synthesis comes adapted;
4. with the said herbal medicine material, be broken into meal, the compound alcohol extract that gets peonol through the ethanol percolation legal system is standby.
Two, the method for making of paeonol health cigarette
1. with moutan bark, paniculate swallowwort, white birch, auricula, alizarin, the six kinds of Chinese herbal medicines of Dian clove of Brazil, pass through steam distillation, artificial chemical synthesis is produced peonol and is extracted the compound alcohol extract of peonol with the ethanol percolation method, this extract is joined in the pipe tobacco, make every cigarette contain the 0.1-5mg peonol, pack then;
2. after described peonol and other perfume additive being mixed, directly join in the pipe tobacco;
With pipe tobacco through CO
2Overcritical benzene get back and described peonol and other perfume additive mix platform even after, drying under reduced pressure was put and is rolled after cold in 2 hours at normal temperatures.
Used supercritical extract displacement method can be removed harmful components in the pipe tobacco, does not have harmful solvent; Extract the eggplant Buddhist nun alcohol in the harmful components, produce the main component of carcinogenic substance BaP when being burning, eggplant Buddhist nun alcohol is again the important source material of medication chemistry through purifying; Compound alcohol extract with peonol adds in the pipe tobacco, can replenish the pipe tobacco degree that cigarette " strength " reduces after the supercritical extract displacement.
Three, embodiment:
1. get 20g peonol (the present invention extracted all can), and add other perfume additive mixing, add again and evenly mix, go up machine in the pipe tobacco of 20kg and roll, make every cigarette contain the 1mg peonol, packing;
Earlier with the 20kg pipe tobacco through CO
2Supercritical extract displacement back is standby, gets compound alcohol extract and other perfume additive mixing that 2kg contains peonol, evenly be sprayed onto again in the standby pipe tobacco, at normal temperatures drying under reduced pressure put in 2 hours cold after, last machine rolls, and makes every cigarette contain the 5mg peonol, packs.
Six kinds of used Chinese herbal medicine resources of the present invention enrich, utilize contained active ingredient peonol, have according to the pharmacological testing proof: anti-inflammation, increase coronary blood flow, improve myocardial metabolism, reduce cardiac muscle cell's endoperoxides fat content, the protection cardiac muscle cell, bring high blood pressure down, and can change the enzyme regioselectivity, suppress the function of the formation of ultimate carcinogen, be that a kind of toxicity is very little, safe range is big, the micromolecular compound of effumability; Make paeonol health cigarette with tobacco cartridge, the smoker is had health-care effect preferably, solved the contradiction of " smoking is with healthy " well.
Claims (3)
1. the preparation method of a paeonol health cigarette, it is characterized in that: with moutan bark, paniculate swallowwort, white birch, ear shape herald spring China, alizarin, the six kinds of Chinese herbal medicines of Dian clove of Brazil, pass through steam distillation, artificial chemical synthesis is produced peonol and is extracted the compound alcohol extract of peonol with the ethanol percolation method, this extract is joined in the pipe tobacco, make every cigarette contain the 0.01-5mg peonol, pack then.
2. with the preparation method of the described paeonol health cigarette of claim 1, it is characterized in that: after described peonol and other perfume additive mix, directly join in the pipe tobacco.
3. by the preparation method of the described paeonol health cigarette of claim 1, it is characterized in that: with pipe tobacco through CO
2After mixing with described peonol and other perfume additive behind the supercritical extract, drying under reduced pressure was put and is rolled after cold in 2 hours at normal temperatures.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96108385 CN1045527C (en) | 1996-07-05 | 1996-07-05 | Paeonol health cigarette and production thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 96108385 CN1045527C (en) | 1996-07-05 | 1996-07-05 | Paeonol health cigarette and production thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN1142338A CN1142338A (en) | 1997-02-12 |
| CN1045527C true CN1045527C (en) | 1999-10-13 |
Family
ID=5119959
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 96108385 Expired - Fee Related CN1045527C (en) | 1996-07-05 | 1996-07-05 | Paeonol health cigarette and production thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN1045527C (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10933030B2 (en) | 2005-05-06 | 2021-03-02 | Angiolab, Inc. | Use of paeonol for inhibiting angiogenesis or for enhancing radiosensitization |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100452998C (en) * | 2005-04-21 | 2009-01-21 | 高勇 | Integrated utilization process for separating solanesol, tobacco extract and residue from waste and inferior tobacco leaf |
| KR100903030B1 (en) | 2007-08-23 | 2009-06-18 | 주식회사 안지오랩 | A fraction of Melissa leaf extract and a composition comprising the same |
| CN105779125A (en) * | 2016-03-18 | 2016-07-20 | 云南中烟工业有限责任公司 | Luculia pinceana Hook.extract with glycerol triacetate serving as extracting agent and application of Luculia pinceana Hook.extract with glycerol triacetate serving as extracting agent to cigarettes |
-
1996
- 1996-07-05 CN CN 96108385 patent/CN1045527C/en not_active Expired - Fee Related
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US10933030B2 (en) | 2005-05-06 | 2021-03-02 | Angiolab, Inc. | Use of paeonol for inhibiting angiogenesis or for enhancing radiosensitization |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1142338A (en) | 1997-02-12 |
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| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C14 | Grant of patent or utility model | ||
| GR01 | Patent grant | ||
| C19 | Lapse of patent right due to non-payment of the annual fee | ||
| CF01 | Termination of patent right due to non-payment of annual fee |