CN104547485A - Externally applied traditional Chinese medicine spray for treating chronic pharyngitis and preparation method of external traditional Chinese medicine spray - Google Patents

Externally applied traditional Chinese medicine spray for treating chronic pharyngitis and preparation method of external traditional Chinese medicine spray Download PDF

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Publication number
CN104547485A
CN104547485A CN201410797838.8A CN201410797838A CN104547485A CN 104547485 A CN104547485 A CN 104547485A CN 201410797838 A CN201410797838 A CN 201410797838A CN 104547485 A CN104547485 A CN 104547485A
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chinese medicine
radix
traditional chinese
medicine spray
externally applied
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王和花
梁化德
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BENGBU CITY MUSSELS MOUNTAIN CULTURE ASSOCIATION
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BENGBU CITY MUSSELS MOUNTAIN CULTURE ASSOCIATION
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Publication of CN104547485A publication Critical patent/CN104547485A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966Fritillaria, e.g. checker lily or mission bells
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/10Dispersions; Emulsions
    • A61K9/12Aerosols; Foams
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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  • Health & Medical Sciences (AREA)
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  • Life Sciences & Earth Sciences (AREA)
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Abstract

The invention relates to an externally applied traditional Chinese medicine spray for treating chronic pharyngitis and a preparation method of the externally applied traditional Chinese medicine spray, relating to the technical field of Chinese herbal medicines. The externally applied traditional Chinese medicine spray disclosed by the invention is composed of the following medicinal raw materials in weight: 18-20g of towel gourd, 5-18g of platycodon grandiflorum, 10-24g of liquorice, 2-12g of white paeony root, 2-12g of radix scrophulariae, 8-20g of oroxylum indicum, 6-18g of chrysanthemum, 5-18g of tendril-leaved fritillary bulb, and 6-15g of radix scrophulariae. The externally applied traditional Chinese medicine spray disclosed by the invention has the beneficial effects that authentic natural traditional Chinese medicinal materials are adopted in the formula; and the externally applied traditional Chinese medicine spray is simple to operate, painless, convenient to store, rapid to take effect, short in treatment course, convenient to use and free from toxic or side effect, and raw materials are easily available.

Description

A kind of external application Chinese medicine spray for the treatment of chronic pharyngitis and preparation method thereof
Technical field
The present invention relates to field of Chinese herbal medicine technology, be specifically related to a kind of external application Chinese medicine spray for the treatment of chronic pharyngitis and preparation method thereof.
Background technology
Chinese medicine is the one country rarity that China exists at present, and Chinese medicine refers to the medicine of application under Chinese tradition medical skill instructs.Chinese medicine is divided into Chinese patent medicine, Chinese crude drug by processing technique.Chinese medicine is originating primarily from China, except plant amedica, animal drugs as Fel Serpentis, Fel Ursi, Agkistrodon, Cornu Cervi Pantotrichum, Cornu Cervi etc.; Shell class as Margarita, Concha Meretricis seu Cyclinae; Mineral substance is as Os Draconis, and Magnetitum etc. are all used to the Chinese medicine of curing the disease.Adopting Chinese medicine to carry out spray making, is mode more prevailing at present, but many times, curative effect is not remarkable, mainly because medical material is selected indefinite, and using method is unreasonable.
Summary of the invention
Technical problem to be solved by this invention is to provide a kind of materials accurately and external application Chinese medicine spray of the treatment chronic pharyngitis that active constituent content is high, absorbability is good and preparation method thereof.
Technical problem to be solved by this invention realizes by the following technical solutions:
Treat an external application Chinese medicine spray for chronic pharyngitis, it is characterized in that: be made up of the crude drug of following weight portion:
Fructus Luffae 18-20g, Radix Platycodonis 5-18g, Radix Glycyrrhizae 10-24g, Radix Paeoniae Alba 2-12g, Radix Scrophulariae 2-12g, Semen Oroxyli 8-20g, Flos Chrysanthemi 6-18g, Bulbus Fritillariae Cirrhosae 5-18g, Radix Scrophulariae 6-15g.
Another object of the present invention is to provide a kind of method preparing medicinal herb spray of the present invention, comprises the following steps:
Each crude drug is taken by following weight:
Fructus Luffae 18g, Radix Platycodonis 10g, Radix Glycyrrhizae 15g, Radix Paeoniae Alba 6g, Radix Scrophulariae 6g, Semen Oroxyli 12g, Flos Chrysanthemi 18g, Bulbus Fritillariae Cirrhosae 10g, Radix Scrophulariae 9g.
Another object of the present invention is to provide a kind of method preparing medicinal herb spray of the present invention, comprises the following steps:
Each crude drug is taken by following weight:
Fructus Luffae 18-20g, Radix Platycodonis 5-18g, Radix Glycyrrhizae 10-24g, Radix Paeoniae Alba 2-12g, Radix Scrophulariae 2-12g, Semen Oroxyli 8-20g, Flos Chrysanthemi 6-18g, Bulbus Fritillariae Cirrhosae 5-18g, Radix Scrophulariae 6-15g.
A, get Fructus Luffae, Radix Platycodonis, Radix Glycyrrhizae, the Radix Paeoniae Alba, Radix Scrophulariae, Semen Oroxyli, Flos Chrysanthemi, Bulbus Fritillariae Cirrhosae, Radix Scrophulariae carry out drying and processing after cleaning up;
B, by above-mentioned steps a dry after raw material carry out pulverizing the container put into and put sealing;
C, the ethanol adding 75% in the container of above-mentioned steps b is carried out immersion 10d;
D, by above-mentioned steps c soak after get lixiviating solution, in lixiviating solution, add the analgesics of 20%, then add the high molecular film former of 10%, load pressure spray bottle in, can use.
Usage and consumption: external.Every 30 minutes spray medicines 1 time, changing every 2 hours after 24 hours into and spray medicine 1 time, 1-3 days is a course for the treatment of.
The invention has the beneficial effects as follows: the external application Chinese medicine spray for the treatment of chronic pharyngitis provided by the invention, have the advantages that medication is accurate, drug absorption is strong, active constituent content is high, evident in efficacy, not easily recur, treatment cycle is short, and using method is simple and easy to do, and raw material is easy to get, cheap, have no side effect.
Detailed description of the invention
The technological means realized to make the present invention, creation characteristic, reaching object and effect is easy to understand, below in conjunction with specific embodiment, setting forth the present invention further.
Embodiment 1
Each crude drug is taken by following weight:
Fructus Luffae 18-20g, Radix Platycodonis 5-18g, Radix Glycyrrhizae 10-24g, Radix Paeoniae Alba 2-12g, Radix Scrophulariae 2-12g, Semen Oroxyli 8-20g, Flos Chrysanthemi 6-18g, Bulbus Fritillariae Cirrhosae 5-18g, Radix Scrophulariae 6-15g.
A, get Fructus Luffae, Radix Platycodonis, Radix Glycyrrhizae, the Radix Paeoniae Alba, Radix Scrophulariae, Semen Oroxyli, Flos Chrysanthemi, Bulbus Fritillariae Cirrhosae, Radix Scrophulariae carry out drying and processing after cleaning up;
B, by above-mentioned steps a dry after raw material carry out pulverizing the container put into and put sealing;
C, the ethanol adding 75% in the container of above-mentioned steps b is carried out immersion 10d;
D, by above-mentioned steps c soak after get lixiviating solution, in lixiviating solution, add the analgesics of 20%, then add the high molecular film former of 10%, load pressure spray bottle in, can use.
Usage and consumption: external.Every 30 minutes spray medicines 1 time, changing every 2 hours after 24 hours into and spray medicine 1 time, 1-3 days is a course for the treatment of.
Embodiment 2
Each crude drug is taken by following weight:
Fructus Luffae 18g, Radix Platycodonis 10g, Radix Glycyrrhizae 15g, Radix Paeoniae Alba 6g, Radix Scrophulariae 6g, Semen Oroxyli 12g, Flos Chrysanthemi 18g, Bulbus Fritillariae Cirrhosae 10g, Radix Scrophulariae 9g.
A, get Fructus Luffae, Radix Platycodonis, Radix Glycyrrhizae, the Radix Paeoniae Alba, Radix Scrophulariae, Semen Oroxyli, Flos Chrysanthemi, Bulbus Fritillariae Cirrhosae, Radix Scrophulariae carry out drying and processing after cleaning up;
B, by above-mentioned steps a dry after raw material carry out pulverizing the container put into and put sealing;
C, the ethanol adding 75% in the container of above-mentioned steps b is carried out immersion 10d;
D, by above-mentioned steps c soak after get lixiviating solution, in lixiviating solution, add the analgesics of 20%, then add the high molecular film former of 10%, load pressure spray bottle in, can use.
Usage and consumption: external.Every 30 minutes spray medicines 1 time, changing every 2 hours after 24 hours into and spray medicine 1 time, 1-3 days is a course for the treatment of.
In order to better verify curative effect of the present invention, below by way of the contrast experiment of curative effect group, matched group, further illustrate medicinal herb spray beneficial effect provided by the invention.
1, grouping and Therapeutic Method
1.1, divide into groups, successively patient is divided into treatment group and matched group at random by consultation time, treatment group 80 example, matched group 80 example;
1.2, treatment group, uses medicinal herb spray provided by the invention to treat patients with chronic pharyngitis;
1.3, matched group, commercially available slow tight Shu Ning treats patients with chronic pharyngitis;
1.4, the course for the treatment of, treatment group and matched group are a course for the treatment of in equal 15 days.
2, the related data for the treatment of group and matched group.
2.1, Sex distribution is in table one:
Table one
Group Number of cases Man Female
Treatment group 80 60 20
Matched group 90 70 20
[0046] 2.2, age distribution is in table two
Table two
2.3, course of disease situation is in table three
Table three
3, efficacy assessment standard
3.1, effective, clinical symptom disappearance, recovers normally to work;
3.2, take a turn for the better, clinical symptom remission, breathe without obviously restriction, work slightly receives impact, occasionally has recurrence.
3.3, invalid, after treating 3 courses for the treatment of, symptom has no alleviation.
Experimental result (after 3 courses for the treatment of) is in table four
Table four
Group Number of cases Effective Take a turn for the better Invalid Total effective rate %
Treatment group 80 43 36 1 95.5%
Matched group 90 36 39 15 84.4%
As can be seen from above experiment, medicinal herb spray provided by the invention has more significant curative effect to chronic pharyngitis.
More than show and describe ultimate principle of the present invention and principal character and advantage of the present invention.The technical staff of the industry should understand; the present invention is not restricted to the described embodiments; what describe in above-described embodiment and description just illustrates principle of the present invention; without departing from the spirit and scope of the present invention; the present invention also has various changes and modifications, and these changes and improvements all fall in the claimed scope of the invention.Application claims protection domain is defined by appending claims and equivalent thereof.

Claims (3)

1. treat an external application Chinese medicine spray for chronic pharyngitis, it is characterized in that: be made up of the raw material of following weight:
Fructus Luffae 18-20g, Radix Platycodonis 5-18g, Radix Glycyrrhizae 10-24g, Radix Paeoniae Alba 2-12g, Radix Scrophulariae 2-12g, Semen Oroxyli 8-20g, Flos Chrysanthemi 6-18g, Bulbus Fritillariae Cirrhosae 5-18g, Radix Scrophulariae 6-15g.
2. the external application Chinese medicine spray for the treatment of chronic pharyngitis according to claim 1, is characterized in that: described quick-dissolving agent is made up of following raw material:
Fructus Luffae 18g, Radix Platycodonis 10g, Radix Glycyrrhizae 15g, Radix Paeoniae Alba 6g, Radix Scrophulariae 6g, Semen Oroxyli 12g, Flos Chrysanthemi 18g, Bulbus Fritillariae Cirrhosae 10g, Radix Scrophulariae 9g.
3. prepare the method for the external application Chinese medicine spray of the treatment chronic pharyngitis of claim 1-2 described in any one, it is characterized in that: comprise the following steps,
A, get Fructus Luffae, Radix Platycodonis, Radix Glycyrrhizae, the Radix Paeoniae Alba, Radix Scrophulariae, Semen Oroxyli, Flos Chrysanthemi, Bulbus Fritillariae Cirrhosae, Radix Scrophulariae carry out drying and processing after cleaning up;
B, by above-mentioned steps a dry after raw material carry out pulverizing the container put into and put sealing;
C, the ethanol adding 75% in the container of above-mentioned steps b is carried out immersion 10d;
D, by above-mentioned steps c soak after get lixiviating solution, in lixiviating solution, add the analgesics of 20%, then add the high molecular film former of 10%, load pressure spray bottle in, can use.
CN201410797838.8A 2014-12-19 2014-12-19 Externally applied traditional Chinese medicine spray for treating chronic pharyngitis and preparation method of external traditional Chinese medicine spray Pending CN104547485A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106377687A (en) * 2016-09-20 2017-02-08 尚伟 Externally applied drug for treating pharyngitis
CN107362271A (en) * 2017-08-03 2017-11-21 华子昂 A kind of Chinese medicine composition for treating breathing problem and preparation method thereof

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1730078A (en) * 2005-08-09 2006-02-08 石新元 Pharynx clearing tea
CN101590179A (en) * 2009-06-26 2009-12-02 王春兰 Traditional Chinese medicine for treating pharyngitis
CN102764288A (en) * 2012-07-28 2012-11-07 聊城大学 Application of luffa water spray for treating acute pharyngitis

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1730078A (en) * 2005-08-09 2006-02-08 石新元 Pharynx clearing tea
CN101590179A (en) * 2009-06-26 2009-12-02 王春兰 Traditional Chinese medicine for treating pharyngitis
CN102764288A (en) * 2012-07-28 2012-11-07 聊城大学 Application of luffa water spray for treating acute pharyngitis

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
刘桂智等: "丝瓜的药用价值", 《北方园艺》 *

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106377687A (en) * 2016-09-20 2017-02-08 尚伟 Externally applied drug for treating pharyngitis
CN107362271A (en) * 2017-08-03 2017-11-21 华子昂 A kind of Chinese medicine composition for treating breathing problem and preparation method thereof

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Application publication date: 20150429