CN104547175A - Traditional Chinese medicine for treating rheumatic heart disease - Google Patents
Traditional Chinese medicine for treating rheumatic heart disease Download PDFInfo
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Abstract
The invention relates to a traditional Chinese medicine for treating rheumatic heart disease. The traditional Chinese medicine comprises the following traditional Chinese medicine in parts by mass: 5-8 part of radix ilicis pubescentis, 4-9 part of radix paeoniae rubra, 8-15 part of cortex erythrinae, 7-12 part of fructus aurantii, 6-10 part of radix ginseng, 8-12 part of folium perillae, 5-9 part of radix bupleuri, 4-6 part of lotus seed pulp, 6-10 part of semen descurainiae, 8-12 part of rhizoma ligustici chuanxiong, 10-14 part of radix astragali seu hedysari, 3-5 part of herba asari, 4-8 part of cortex acanthopanax radices and 5-8 part of herba leonuri. The traditional Chinese medicine has the efficacies of regulating vital energy and promoting blood circulation, and clearing away heat and removing dampness by adopting the reasonable traditional Chinese medicine formula in which all the traditional Chinese medicines are combined and synergistic. All the traditional Chinese medicines are combined, thus being capable of nourishing yin and clearing heat without affecting relieving of exterior syndrome, and inducing sweat and dispelling exogenous evils without damaging yin qi; and the traditional Chinese medicine has better effect on treatment of rheumatic heart disease. For five years, through the use by 145 patients, the traditional Chinese medicine can effectively treat rheumatic heart disease, with the effective rate up to 88.5%.
Description
Technical field
The present invention relates to a kind of Chinese medicine for the treatment of rheumatic heart disease, belong to Chinese medicine formula technical field.
Background technology
Rheumatic heart disease is called for short rheumatic heart disease, refers to due to rheumatic fever activity, involves cardiac valve and the valve disorder that causes.Show as in Bicuspid valve, Tricuspid valve, aortic valve and have one or several valvular stenosis and (or) incompetence.Narrow or incompetence often exists simultaneously clinically, but normal based on one.Usually non-evident sympton of ill initial stage, stage shows as palpitation and short breath, weak, cough, lower limbs edema, cough the cardiac function such as pink foam expectorant loses compensatory performance.Primary disease is mainly in winter-spring season, under cold, humidity and crowded environment.Chinese traditional treatment, from entirety, has the advantage of comprehensive function, is thus paid close attention to widely.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine for the treatment of rheumatic heart disease, by selecting suitable medical material and proportioning thereof, reach safe and effective treatment rheumatic heart disease object.
To achieve these goals, technical scheme of the present invention is as follows.
Treat a Chinese medicine for rheumatic heart disease, be made up of the Chinese medicine of following quality proportioning: Radix Ilicis Pubescentis 5 ~ 8 parts, Radix Paeoniae Rubra 4 ~ 9 parts, Cortex erythrinae 8 ~ 15 parts, Fructus Aurantii 7 ~ 12 parts, Radix Ginseng 6 ~ 10 parts, Folium Perillae 8 ~ 12 parts, Radix Bupleuri 5 ~ 9 parts, Semen Nelumbinis 4 ~ 6 parts, Semen Lepidii (Semen Descurainiae) 6 ~ 10 parts, Rhizoma Chuanxiong 8 ~ 12 parts, the Radix Astragali 10 ~ 14 parts, Herba Asari 3 ~ 5 parts, Cortex Acanthopancis 4 ~ 8 parts, Herba Leonuri 5 ~ 8 parts.
Further, the Chinese medicine of above-mentioned treatment rheumatic heart disease, is made up of the Chinese medicine of following quality proportioning: Radix Ilicis Pubescentis 6 parts, Radix Paeoniae Rubra 5 parts, Cortex erythrinae 8 parts, Fructus Aurantii 8 parts, Radix Ginseng 8 parts, Folium Perillae 10 parts, Radix Bupleuri 6 parts, Semen Nelumbinis 4 parts, Semen Lepidii (Semen Descurainiae) 6 parts, Rhizoma Chuanxiong 8 parts, the Radix Astragali 10 parts, Herba Asari 3 parts, Cortex Acanthopancis 5 parts, Herba Leonuri 6 parts.
Further, the Chinese medicine of above-mentioned treatment rheumatic heart disease, is made up of the Chinese medicine of following quality proportioning: Radix Ilicis Pubescentis 8 parts, Radix Paeoniae Rubra 9 parts, Cortex erythrinae 12 parts, Fructus Aurantii 12 parts, Radix Ginseng 10 parts, Folium Perillae 8 parts, Radix Bupleuri 9 parts, Semen Nelumbinis 5 parts, Semen Lepidii (Semen Descurainiae) 10 parts, Rhizoma Chuanxiong 10 parts, the Radix Astragali 12 parts, Herba Asari 5 parts, Cortex Acanthopancis 8 parts, Herba Leonuri 8 parts.
Further, the Chinese medicine of above-mentioned treatment rheumatic heart disease, is made up of the Chinese medicine of following quality proportioning: Radix Ilicis Pubescentis 5 parts, Radix Paeoniae Rubra 9 parts, Cortex erythrinae 15 parts, Fructus Aurantii 7 parts, Radix Ginseng 6 parts, Folium Perillae 12 parts, Radix Bupleuri 5 parts, Semen Nelumbinis 6 parts, Semen Lepidii (Semen Descurainiae) 8 parts, Rhizoma Chuanxiong 12 parts, the Radix Astragali 14 parts, Herba Asari 4 parts, Cortex Acanthopancis 4 parts, Herba Leonuri 5 parts.
(1) Radix Ilicis Pubescentis: be the root of holly plant Radix Ilicis Pubescentis.Mildly bitter flavor is sweet, and property is put down, nontoxic.Function cures mainly: loose wind heat, refresh oneself, relieving thirst and restlessness.Modern pharmacological research then proves, the trace element such as the several amino acids not only containing needed by human in Folium Ilicis Pubescentis, vitamin and zinc, manganese, rubidium, also there is blood fat reducing, increase coronary artery blood flow, increase the effect such as blood supply of cardiac muscle, atherosclerosis, all have good preventive and therapeutic effect to symptoms such as the dizziness of Patients with Cardiovascular/Cerebrovascular Diseases, headache, uncomfortable in chest, weak, insomnias.
(2) Radix Paeoniae Rubra: be the dry root of ranunculaceae plant Radix Paeoniae Rubra or river Radix Paeoniae Rubra.Spring, Qiu Erji excavate, and removing rhizome, fibrous root and silt, dry.Hardship, is slightly cold.Return Liver Channel.There is clearing away heat and cooling blood, effect of blood circulation promoting and blood stasis dispelling.For thermal man's nutrient blood, maculae caused by violent heat pathogen, hematemesis and epistaxis, conjunctival congestion and swelling pain, hypochondriac pain due to stagnation of liverQI, amenorrhea dysmenorrhea, addiction abdominal mass is suffered from abdominal pain, injury from falling down, carbuncle skin infection.
(3) Cortex erythrinae: bitter, pungent is flat.Enter liver, spleen two warp.Hardship can dampness damp eliminating, pungently walks to alter circulation of qi promoting, and property is flat biased without cold and heat, and arthralgia due to cold, pyretic arthralgia all can be applied.Especially imitate good to rheumatism arthromyodynia, spasm of the limbs, lumbocrural pain.
(4) Fructus Aurantii: [nature and flavor] toil is cool.[return through] enters lung, spleen, large intestine channel.[function cures mainly] dispelling the stagnated QI, row expectorant, removing food stagnancy.Control chest and diaphragm expectorant stagnant, the feeling of stuffiness in chest, coerce swollen, food stagnation, eructation, vomiting, heavy after dysentery, proctoptosis, uterine prolapse.
(5) Radix Ginseng: property is flat, sweet in the mouth, micro-hardship, tepor.Return spleen, lung meridian.Effect: strongly invigorating primordial QI, multiple arteries and veins takes off admittedly, invigorating the spleen to benefit the lung, promoting the production of body fluid to quench thirst, Fructus Alpiniae Oxyphyllae of calming the nerves.Cure mainly: impairment caused by overstrain is deficient, food is told in lack of appetite, asthenia, regurgitation, stool lingering diarrhea, empty cough with asthma are short, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, frequent micturition, quench one's thirst, woman uterine bleeding, children's's intermittent infantile convulsion and prolonged deficiency be multiple, the card of all qi-blood-body fluid deficiencies.
(6) Folium Perillae: acrid in the mouth, warm in nature.Return lung, spleen channel.Induce sweat cold expelling, relieving QI stagnancy in the stomach.For anemofrigid cold, cough vomiting and nausea, vomiting during pregnancy, fish Eriocheir sinensis is poisoning.Folium Perillae can fall apart exterior cold, and diaphoresis power is comparatively strong, for wind and cold table disease, sees aversion to cold, heating, the disease such as lossless.
(7) Radix Bupleuri: induce sweat and bring down a fever; Dispersing the stagnated live-QI to relieve the stagnation of QI, elevate a turnable ladder yang-energy.Main fever caused by exogenous pathogens; Alternate attack of chill and fever; Malaria; Hypochondriac pain due to stagnation of liverQI mammary swelling; Headache dizziness; Menoxenia; The proctoptosis of collapse of QI; Uterine prolapse; Gastroptosis.Its composition mainly contains saikoside, sterol, volatile oil (bupleurumol, eugenol etc.), fatty oil (oleic acid, linoleic acid, Palmic acid, stearic acid etc.) and polysaccharide etc.In addition, still containing alkaloid, flavonoid, Rhizoma Kaempferiae glycosides, glucose, aminoacid etc.
(8) Semen Nelumbinis: property is flat, sweet-puckery flavor, enters the heart, spleen, kidney channel; Spleen reinforcing antidiarrheal, kidney tonifying is clearly puckery, tranquilizing by nourishing the heart.For insufficiency of the spleen chronic diarrhea, seminal emission leukorrhagia, palpitation and insomnia.Cure mainly dreaminess of sleeping night, insomnia, forgetful, restlessness and thirst, lumbago flaccidity of the lower limbs, dysfunction of vision and hearing, seminal emission, stranguria with turbid discharge, chronic dysentery, diarrhea of deficiency type, the diseases such as woman uterine bleeding leukorrhagia and insufficiency of stomach loss of appetite.Semen Nelumbinis are good at tonifying five ZANG-organs deficiency, tonneau twelve regular channels QI and blood, make QI and blood smooth and are stale-proof.Contained by Semen Nelumbinis, noncrystalline shape alkaloid N-9 has hypotensive activity.The core that Semen Nelumbinis central authorities are green, claim embryo nelumbinis, containing the multiple alkaloid such as liensinine, isoliensinine, taste is extremely bitter, has the function of clearing away heat-fire, also has significant cardiotonic, can expand peripheral blood vessel, reduce blood pressure.
(9) Semen Lepidii (Semen Descurainiae): nature and flavor: pungent; Bitter; Cold.Gui Jing: lung meridian; Heart channel; Liver Channel; Stomach warp; Urinary bladder channel.Function: eliminating the pathogens from the lung sending down the abnormal ascending QI; Eliminating phlegm and relieving asthma; Inducing diuresis to remove edema; Let out by heresy.Cure mainly: sputum stops up the dyspnea and cough with excessive sputum of lung; Lung abscess; Edema; Breast abdomen hydrops; Dysuria; Chronic pulmonary heart disease; Breathing heavily of heart failure is swollen; Scrofula tuberculosis.
(10) Rhizoma Chuanxiong: enter liver, gallbladder meridian.Function cures mainly: activating QI to alleviate the depression, and method wind-dryness is wet, promoting blood circulation and stopping pain.Controlling air-cooled headache revolves dizzy, and hypochondriac pain abdomen aches, arthralgia due to cold clonic spasm of the muscle, amenorrhea, difficult labour, postpartum stagnation block pain, ulcer sores.For menoxenia, amenorrhea dysmenorrhea, abdominal mass is suffered from abdominal pain, the twinge of the breast side of body, tumbling and swelling, headache, rheumatic arthralgia.
(11) Radix Astragali: sweet in the mouth slightly warm in nature.Return lung, spleen, liver, kidney channel.Polishing consolidating superficial resistance, holder skin ulcer granulation promoting.Cure mainly the empty spontaneous perspiration of body, chronic diarrhea, proctoptosis, uterine prolapse, chronic nephritis, body is impractical swollen, chronic ulcer, open sore part disunion of a specified duration.The life Radix Astragali, has effect of benefiting QI for strengthening the superficies, inducing diuresis to remove edema, detoxification, granulation promoting, is applicable to spontaneous perspiration, night sweat, arthralgia due to stagnation of blood, edema, carbuncle and does not burst or burst and the disease such as not hold back for a long time.Radix Astragali (processed with Mel) has QI invigorating, nourishes blood, effect in benefit, is applicable to the diseases such as internal injury overstrain, diarrhea due to hypofunction of the spleen, the deficiency of vital energy, blood deficiency, weakness of QI.Modern medicine proves; the Radix Astragali have reduce blood viscosity, reduce thrombosis, reduce blood pressure, cardioprotection, two-ways regulation blood glucose, free radical resisting damage, defying age, anti-hypoxia, antitumor, the effect of enhancing human body immunity power, can be used to treat the disease such as heart disease, hypertension, diabetes.The Radix Astragali can also blood vessel dilating, improves cutaneous circulation and nutriture, therefore effective to chronic ulcer disunion person of a specified duration.It can also eliminate the albuminuria of nephritis patient, the liver protecting, prevents hepatic glycogen from reducing.
(12) Herba Asari: [nature and flavor] are pungent, temperature.[return through] enters lung, kidney channel.[function cures mainly] dispels the wind, cold expelling, and row water, has one's ideas straightened out.Control air-cooled headache, nasal sinusitis, toothache, phlegm retention cough with dyspnea, rheumatic arthralgia.
(13) Cortex Acanthopancis: wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening.
(14) Herba Leonuri: intact animal's platelet aggregation that Herba Leonuri and extract thereof have antagonism ADP to induce.Experiment in vivo also proves that Herba Leonuri significantly can reduce platelet and aggregation thereof in total number of blood platelet in peripheral circulation and alveolar wall blood capillary.Herba Leonuri has remarkable dissolution to rabbit pulmonary circulation red thrombus.In addition, Herba Leonuri also has the effects such as the cellular immunization of enhancing body.Herba Leonuri can promote recovering very soon of the regional flow's microcirculation disturbance caused by isoproterenol, significantly can increase coronary flow and decreased heart rate quite significantly, have reduction coronary resistance, decreased heart rate and reduce the effect of output and left ventricular work.
The traditional Chinese medical science thinks that rheumatic heart disease is that impatency passages through which vital energy circulates causes due to the exopathogen such as wind, cold, wet, heat invasion and attack human body.Compared with general rheumatism, rheumatism is a kind of chronic disease, easily repeatedly occurs acute attack.But at After acute stage, even if redness disappears, joint is indeformable, function seems to recover completely, is still not equal to and recovers completely.There will be the little erythema of not aching and not itching with it during rheumatism outbreak, just disappear two days later; Sometimes extremity or scalp also there will be unnoticed little scleroma.Especially it is appreciated that the pathological changes caused after recurrent exerbation, heart is damaged, and from occurring having palpitation, breathe hard, become thin, the pathological changes such as hyperhidrosis is rheumatic heart disease.
Rheumatic heart disease Chinese medical discrimination is divided into that asthenia of qi and blood loses, disease sees the types such as cardiopalmus stasis blocking, deficiency of heart-YANG and kidney-YANG.Be common with lung network blood stasis blocking type clinically.This kind of pathological characteristic is that exopathogen enters body, and involve heart, dampness blood stasis, cardiopulmonary are impaired.Therefore method for the treatment of gives prominence to dampness removing and blood stasis dispelling develops simultaneously, i.e. " dampness removing is double invigorates blood circulation, invigorate blood circulation must dampness removing ".In this formula, with ginseng qi-tonifying with eliminating evil, with Folium Perillae dispelling wind to relieve the exterior syndrome, with Fructus Aurantii a surname reason lung qi, preventing phlegm from forming and stopping coughing, to fall apart wind damp eliminating with Cortex erythrinae, removing obstruction in the collateral to relieve pain and the property of medicine is not warm, exempts from the fraud of dry impairment of YIN.The present invention adopts rational Chinese prescription, and all medicine phases 5 in prescription, synergism, has effect of vital energy regualting and blood circulation-promoting, removing damp-heat.All medicines coordinates, and can nourishing YIN and clearing away heat and not hindering induce sweat, relieving the exterior syndrome by diaphoresis and non-impairment of YIN gas, has better effects to treatment rheumatic heart disease.Over 5 years, by showing the use of 145 patients, this medicine effectively can treat rheumatic heart disease, and effective percentage reaches 88.5%.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, physical data: inventor have collected 140 routine rheumatic heart disease out-patients between in August ,-2014 in May, 2009 altogether, wherein, man 76 example, female 64 example, 30 ~ 59 years old age, the state of an illness 6 months ~ 4 years.Be divided at random: treatment group 70 example, matched group 70 example.The data there was no significant differences such as two groups of ages, have comparability.
2, test method: the oral YINQIAO Baihu Tang of (1) matched group, takes to specifications.30 days courses for the treatment of.(2) the oral the present invention for the treatment of group is according to the obtained capsule of specific embodiment 1, early, middle and late each once.30 days courses for the treatment of.(3) criterion of therapeutical effect and therapeutic outcome: criterion of therapeutical effect: recovery from illness: the clinical symptoms of rheumatic heart disease all disappears.Take a turn for the better: the clinical symptom relief of rheumatic heart disease, the state of an illness is controlled.Invalid: the clinical symptoms of rheumatic heart disease is without being clearly better or increasing the weight of.Treatment statistical result is in table 1.
Table 1 liang group comparitive study
As can be seen here, the medicine adopting prescription of the present invention obtained can safe and effective treatment rheumatic heart disease.
Detailed description of the invention
Below in conjunction with embodiment, the specific embodiment of the present invention is described, better to understand the present invention.
specific embodiment 1
Take Radix Ilicis Pubescentis 6 grams, Radix Paeoniae Rubra 5 grams, Cortex erythrinae 8 grams, Fructus Aurantii 8 grams, Radix Ginseng 8 grams, Folium Perillae 10 grams, Radix Bupleuri 6 grams, Semen Nelumbinis 4 grams, Semen Lepidii (Semen Descurainiae) 6 grams, Rhizoma Chuanxiong 8 grams, the Radix Astragali 10 grams, Herba Asari 3 grams, Cortex Acanthopancis 5 grams, Herba Leonuri 6 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, mix homogeneously, incapsulates shell, must meet the capsule of adult normal's 1 day consumption.
Be used for the treatment of rheumatic heart disease, oral, every bu is taken for early, middle and late three times.
specific embodiment 2
Take Radix Ilicis Pubescentis 8 grams, Radix Paeoniae Rubra 9 grams, Cortex erythrinae 12 grams, Fructus Aurantii 12 grams, Radix Ginseng 10 grams, Folium Perillae 8 grams, Radix Bupleuri 9 grams, Semen Nelumbinis 5 grams, Semen Lepidii (Semen Descurainiae) 10 grams, Rhizoma Chuanxiong 10 grams, the Radix Astragali 12 grams, Herba Asari 5 grams, Cortex Acanthopancis 8 grams, Herba Leonuri 8 grams, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, close evenly, packaging, must meet the powder of adult normal's 1 day consumption.
Be used for the treatment of rheumatic heart disease, oral, every bu is taken for early, middle and late three times.
specific embodiment 3
Take Radix Ilicis Pubescentis 5 grams, Radix Paeoniae Rubra 9 grams, Cortex erythrinae 15 grams, Fructus Aurantii 7 grams, Radix Ginseng 6 grams, Folium Perillae 12 grams, Radix Bupleuri 5 grams, Semen Nelumbinis 6 grams, Semen Lepidii (Semen Descurainiae) 8 grams, Rhizoma Chuanxiong 12 grams, the Radix Astragali 14 grams, Herba Asari 4 grams, Cortex Acanthopancis 4 grams, Herba Leonuri 5 grams, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, mix homogeneously, granulates according to this area common process, and packaging, must meet the granule of adult normal's 1 day consumption.
Be used for the treatment of rheumatic heart disease, oral, every bu is taken for early, middle and late three times.
The above is the preferred embodiment of the present invention; it should be pointed out that for those skilled in the art, under the premise without departing from the principles of the invention; can also make some improvements and modifications, these improvements and modifications are also considered as protection scope of the present invention.
Claims (4)
1. treat a Chinese medicine for rheumatic heart disease, it is characterized in that: be made up of the Chinese medicine of following quality proportioning: Radix Ilicis Pubescentis 5 ~ 8 parts, Radix Paeoniae Rubra 4 ~ 9 parts, Cortex erythrinae 8 ~ 15 parts, Fructus Aurantii 7 ~ 12 parts, Radix Ginseng 6 ~ 10 parts, Folium Perillae 8 ~ 12 parts, Radix Bupleuri 5 ~ 9 parts, Semen Nelumbinis 4 ~ 6 parts, Semen Lepidii (Semen Descurainiae) 6 ~ 10 parts, Rhizoma Chuanxiong 8 ~ 12 parts, the Radix Astragali 10 ~ 14 parts, Herba Asari 3 ~ 5 parts, Cortex Acanthopancis 4 ~ 8 parts, Herba Leonuri 5 ~ 8 parts.
2. the Chinese medicine for the treatment of rheumatic heart disease according to claim 1, is characterized in that: described formula is made up of the Chinese medicine of following quality proportioning: Radix Ilicis Pubescentis 6 parts, Radix Paeoniae Rubra 5 parts, Cortex erythrinae 8 parts, Fructus Aurantii 8 parts, Radix Ginseng 8 parts, Folium Perillae 10 parts, Radix Bupleuri 6 parts, Semen Nelumbinis 4 parts, Semen Lepidii (Semen Descurainiae) 6 parts, Rhizoma Chuanxiong 8 parts, the Radix Astragali 10 parts, Herba Asari 3 parts, Cortex Acanthopancis 5 parts, Herba Leonuri 6 parts.
3. the Chinese medicine for the treatment of rheumatic heart disease according to claim 1, is characterized in that: described formula is made up of the Chinese medicine of following quality proportioning: Radix Ilicis Pubescentis 8 parts, Radix Paeoniae Rubra 9 parts, Cortex erythrinae 12 parts, Fructus Aurantii 12 parts, Radix Ginseng 10 parts, Folium Perillae 8 parts, Radix Bupleuri 9 parts, Semen Nelumbinis 5 parts, Semen Lepidii (Semen Descurainiae) 10 parts, Rhizoma Chuanxiong 10 parts, the Radix Astragali 12 parts, Herba Asari 5 parts, Cortex Acanthopancis 8 parts, Herba Leonuri 8 parts.
4. the Chinese medicine for the treatment of rheumatic heart disease according to claim 1, is characterized in that: described formula is made up of the Chinese medicine of following quality proportioning: Radix Ilicis Pubescentis 5 parts, Radix Paeoniae Rubra 9 parts, Cortex erythrinae 15 parts, Fructus Aurantii 7 parts, Radix Ginseng 6 parts, Folium Perillae 12 parts, Radix Bupleuri 5 parts, Semen Nelumbinis 6 parts, Semen Lepidii (Semen Descurainiae) 8 parts, Rhizoma Chuanxiong 12 parts, the Radix Astragali 14 parts, Herba Asari 4 parts, Cortex Acanthopancis 4 parts, Herba Leonuri 5 parts.
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| CN1555866A (en) * | 2004-01-05 | 2004-12-22 | 广州中一药业有限公司 | Medicine for treating congestion arhythmia and its preparation method |
| CN102961491A (en) * | 2012-10-26 | 2013-03-13 | 郗光敏 | Traditional Chinese medicine composition for treating chronic congestive heart failure |
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2015
- 2015-01-15 CN CN201510019900.5A patent/CN104547175A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1555866A (en) * | 2004-01-05 | 2004-12-22 | 广州中一药业有限公司 | Medicine for treating congestion arhythmia and its preparation method |
| CN102961491A (en) * | 2012-10-26 | 2013-03-13 | 郗光敏 | Traditional Chinese medicine composition for treating chronic congestive heart failure |
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Application publication date: 20150429 |