CN104541169B - 个体的结核感染状态 - Google Patents

个体的结核感染状态 Download PDF

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Publication number
CN104541169B
CN104541169B CN201380038250.8A CN201380038250A CN104541169B CN 104541169 B CN104541169 B CN 104541169B CN 201380038250 A CN201380038250 A CN 201380038250A CN 104541169 B CN104541169 B CN 104541169B
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China
Prior art keywords
monocytes
aladh
individual
level
tuberculosis
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Expired - Fee Related
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CN201380038250.8A
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English (en)
Chinese (zh)
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CN104541169A (zh
Inventor
M·辛格
M·M·德莱斯
贝拉 C·黛拉
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LIONEX GmbH
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LIONEX GmbH
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6863—Cytokines, i.e. immune system proteins modifying a biological response such as cell growth proliferation or differentiation, e.g. TNF, CNF, GM-CSF, lymphotoxin, MIF or their receptors
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/195—Assays involving biological materials from specific organisms or of a specific nature from bacteria
    • G01N2333/35—Assays involving biological materials from specific organisms or of a specific nature from bacteria from Mycobacteriaceae (F)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52—Assays involving cytokines
    • G01N2333/54—Interleukins [IL]
    • G01N2333/55—IL-2
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90—Enzymes; Proenzymes
    • G01N2333/902—Oxidoreductases (1.)
    • G01N2333/906—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7)
    • G01N2333/90605—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4)
    • G01N2333/90611—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1) in general
    • G01N2333/90616—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.7) acting on the CH-NH2 group of donors (1.4) with NAD or NADP as acceptor (1.4.1) in general with a definite EC number (1.4.1.-)

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Cell Biology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
CN201380038250.8A 2012-07-16 2013-07-16 个体的结核感染状态 Expired - Fee Related CN104541169B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP12176506.9A EP2687848A1 (en) 2012-07-16 2012-07-16 Status of tuberculosis infection in an individual
EP12176506.9 2012-07-16
PCT/EP2013/065002 WO2014012928A1 (en) 2012-07-16 2013-07-16 Status of tuberculosis infection in an individual

Publications (2)

Publication Number Publication Date
CN104541169A CN104541169A (zh) 2015-04-22
CN104541169B true CN104541169B (zh) 2017-09-15

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ID=48795573

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201380038250.8A Expired - Fee Related CN104541169B (zh) 2012-07-16 2013-07-16 个体的结核感染状态

Country Status (13)

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EP (2) EP2687848A1 (https=)
CN (1) CN104541169B (https=)
AU (1) AU2013292040B2 (https=)
CA (1) CA2878497C (https=)
DK (1) DK2872896T3 (https=)
EA (1) EA030721B1 (https=)
ES (1) ES2666073T3 (https=)
IN (1) IN2015MN00140A (https=)
NO (1) NO2872896T3 (https=)
PL (1) PL2872896T3 (https=)
PT (1) PT2872896T (https=)
WO (1) WO2014012928A1 (https=)
ZA (1) ZA201500254B (https=)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP3171170A1 (en) * 2015-11-17 2017-05-24 Lionex GmbH Device for use in elispot
KR20180104038A (ko) * 2016-01-20 2018-09-19 시아먼 유니버시티 활동성 결핵의 진단을 위한 방법 및 키트
CN106501530A (zh) * 2017-01-05 2017-03-15 复旦大学附属华山医院 一种诊断结核杆菌感染的生物标志物及其相关试剂盒
RU2726789C1 (ru) * 2020-01-17 2020-07-15 Федеральное государственное бюджетное учреждение "Национальный медицинский исследовательский центр фтизиопульмонологии и инфекционных заболеваний" Министерства здравоохранения Российской Федерации (ФГБУ "НМИЦ ФПИ" Минздрава России) Способ иммунологического определения активности туберкулезной инфекции у детей и подростков с латентной инфекцией
CN115598353B (zh) * 2022-10-24 2024-09-13 首都医科大学附属北京胸科医院 细胞因子作为标记物在制备肺外结核诊断或治疗预后产品中的应用

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020094336A1 (en) * 1997-04-02 2002-07-18 Statens Serum Institut Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis
US20070026473A1 (en) * 2005-07-26 2007-02-01 Gennaro Maria L Antibody profiles characteristic of tuberculosis state
CN101868724A (zh) * 2007-10-29 2010-10-20 自体免疫诊断有限责任公司 用于体外诊断和/或体外治疗监测感染的方法
CN102033129A (zh) * 2009-09-29 2011-04-27 上海英伯肯医学生物技术有限公司 用抗原刺激的细胞免疫反应来检测病原微生物的方法及测试笔

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998036089A2 (de) 1997-01-29 1998-08-20 Flohe Leopold Testkit für tuberkulosediagnose durch bestimmung von alanindehydrogenase

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020094336A1 (en) * 1997-04-02 2002-07-18 Statens Serum Institut Nucleic acid fragments and polypeptide fragments derived from M. tuberculosis
US20070026473A1 (en) * 2005-07-26 2007-02-01 Gennaro Maria L Antibody profiles characteristic of tuberculosis state
CN101868724A (zh) * 2007-10-29 2010-10-20 自体免疫诊断有限责任公司 用于体外诊断和/或体外治疗监测感染的方法
CN102033129A (zh) * 2009-09-29 2011-04-27 上海英伯肯医学生物技术有限公司 用抗原刺激的细胞免疫反应来检测病原微生物的方法及测试笔

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
Antibody markers of incident tuberculosis among HIV-infected;M. L. Gennaro,et al;《INT J TUBERC LUNG DIS》;20071231;第11卷(第6期);624-631 *
Hla-A2-restricted CD8+-cytotoxic-T-cell responses to novel epitopes in Mycobacterium tuberculosis superoxide dismutase, alanine dehydrogenase, and glutamine synthetase;Yuzhi Dong，et al;《INFECTION AND IMMUNITY》;20040430;第72卷(第4期);第2412页左栏第2段至右栏第2段，第2413页左栏第3段至第2414页右栏第1段 *
Latent tuberculosis infection in children: diagnostic;V. Amanatidou，et al;《Eur J Clin Microbiol Infect Dis》;20120104;第31卷;1285-1294 *
结核分枝杆菌蛋白抗原T细胞表位的研究进展;彭美玉等;《蚌埠医学院学报》;20110430(第04期);第424页左栏第2段 *

Also Published As

Publication number Publication date
CA2878497A1 (en) 2014-01-23
ES2666073T3 (es) 2018-04-30
EP2872896A1 (en) 2015-05-20
PL2872896T3 (pl) 2018-08-31
EP2872896B1 (en) 2017-12-27
CA2878497C (en) 2021-06-08
AU2013292040B2 (en) 2018-07-12
AU2013292040A1 (en) 2015-02-05
PT2872896T (pt) 2018-04-02
DK2872896T3 (en) 2018-04-09
CN104541169A (zh) 2015-04-22
EA201590220A1 (ru) 2015-06-30
IN2015MN00140A (https=) 2015-10-16
ZA201500254B (en) 2016-06-29
NO2872896T3 (https=) 2018-05-26
EA030721B1 (ru) 2018-09-28
WO2014012928A1 (en) 2014-01-23
EP2687848A1 (en) 2014-01-22

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