CN104540938A - 治疗方法 - Google Patents

治疗方法 Download PDF

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Publication number
CN104540938A
CN104540938A CN201280069662.3A CN201280069662A CN104540938A CN 104540938 A CN104540938 A CN 104540938A CN 201280069662 A CN201280069662 A CN 201280069662A CN 104540938 A CN104540938 A CN 104540938A
Authority
CN
China
Prior art keywords
cells
mice
hippocampus
nrp2
neural crest
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201280069662.3A
Other languages
English (en)
Chinese (zh)
Inventor
A·洛佩兹
Q·施瓦茨
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medvet Science Pty Ltd
Original Assignee
Medvet Science Pty Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AU2011905180A external-priority patent/AU2011905180A0/en
Application filed by Medvet Science Pty Ltd filed Critical Medvet Science Pty Ltd
Publication of CN104540938A publication Critical patent/CN104540938A/zh
Pending legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32—Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0623—Stem cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Chemistry (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Psychiatry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Ophthalmology & Optometry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Dermatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pain & Pain Management (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN201280069662.3A 2011-12-13 2012-12-13 治疗方法 Pending CN104540938A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AU2011905180A AU2011905180A0 (en) 2011-12-13 Method of treatment
AU2011905180 2011-12-13
PCT/AU2012/001530 WO2013086574A1 (en) 2011-12-13 2012-12-13 Method of treatment

Publications (1)

Publication Number Publication Date
CN104540938A true CN104540938A (zh) 2015-04-22

Family

ID=48611719

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201280069662.3A Pending CN104540938A (zh) 2011-12-13 2012-12-13 治疗方法

Country Status (9)

Country Link
US (1) US20140348793A1 (enExample)
EP (1) EP2791324B1 (enExample)
JP (1) JP2015500297A (enExample)
KR (1) KR20140116103A (enExample)
CN (1) CN104540938A (enExample)
AU (1) AU2012350357A1 (enExample)
CA (1) CA2859213A1 (enExample)
IN (1) IN2014DN05769A (enExample)
WO (1) WO2013086574A1 (enExample)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20230218213A1 (en) * 2020-07-02 2023-07-13 The Johns Hopkins University Fmri-hippocampus acoustic battery (fhab)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000052143A2 (en) * 1999-03-05 2000-09-08 California Institute Of Technology The isolation and enrichment of neural stem cells from uncultured tissue based on cell-surface marker expression
CN101384708A (zh) * 2006-02-20 2009-03-11 泰斯拉博有限公司 从成人牙周滤泡组织中收集和分离胚胎样干细胞群的方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011096728A2 (en) * 2010-02-03 2011-08-11 Samsung Life Public Welfare Foundation Method for proliferating stem cells by activating c-met/hgf signaling and notch signaling
AU2012313353B2 (en) * 2011-09-22 2018-03-08 Precision Medicine Holdings Pty Ltd Screening method

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000052143A2 (en) * 1999-03-05 2000-09-08 California Institute Of Technology The isolation and enrichment of neural stem cells from uncultured tissue based on cell-surface marker expression
CN101384708A (zh) * 2006-02-20 2009-03-11 泰斯拉博有限公司 从成人牙周滤泡组织中收集和分离胚胎样干细胞群的方法

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
RAGAD EL SEADY ET AL.: "Uncomplicated differentiation of stem cells into bipolar neurons and myelinating glia", 《BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS》 *
SCHWARZ Q ET AL.: "Neuropilin-mediated neural crest cell guidance is essential to organise sensory neurons into segmented dorsal root ganglia.", 《DEVELOPMENT》 *
卢静等: "躯干神经嵴干细胞体外分离培养及其增殖、分化的实验研究", 《山东大学学报（医学版）》 *

Also Published As

Publication number Publication date
JP2015500297A (ja) 2015-01-05
CA2859213A1 (en) 2013-06-20
US20140348793A1 (en) 2014-11-27
AU2012350357A1 (en) 2014-07-24
IN2014DN05769A (enExample) 2015-04-10
EP2791324B1 (en) 2017-05-10
EP2791324A4 (en) 2015-04-29
EP2791324A1 (en) 2014-10-22
WO2013086574A1 (en) 2013-06-20
KR20140116103A (ko) 2014-10-01

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Application publication date: 20150422

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