CN104529709B - Phenyl propanediol derivative, Preparation Method And The Use - Google Patents
Phenyl propanediol derivative, Preparation Method And The Use Download PDFInfo
- Publication number
- CN104529709B CN104529709B CN201510021682.9A CN201510021682A CN104529709B CN 104529709 B CN104529709 B CN 104529709B CN 201510021682 A CN201510021682 A CN 201510021682A CN 104529709 B CN104529709 B CN 104529709B
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- China
- Prior art keywords
- compound
- present
- preparation
- sglt2
- diabetes
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- JFMBRUXGCNQLQA-RUINGEJQSA-N CC(c1ccc(C[C@@H](CO)O)cc1C1)c2c1ccc(C)c2 Chemical compound CC(c1ccc(C[C@@H](CO)O)cc1C1)c2c1ccc(C)c2 JFMBRUXGCNQLQA-RUINGEJQSA-N 0.000 description 1
- BUSFWQGAXLUXBO-AOMKIAJQSA-N C[C@@H]([C@H](Cc1ccc(C)c(Cc2ccc(C3=CCC3)cc2)c1)O)O Chemical compound C[C@@H]([C@H](Cc1ccc(C)c(Cc2ccc(C3=CCC3)cc2)c1)O)O BUSFWQGAXLUXBO-AOMKIAJQSA-N 0.000 description 1
Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
Abstract
Description
Compound number | IC 50(hSGLT2,nM) |
I-1 | 11.4 |
I-2 | 13.1 |
I-3 | 19.5 |
I-4 | 17.9 |
I-5 | 27.3 |
I-6 | 24.7 |
Claims (2)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510021682.9A CN104529709B (en) | 2015-01-15 | 2015-01-15 | Phenyl propanediol derivative, Preparation Method And The Use |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201510021682.9A CN104529709B (en) | 2015-01-15 | 2015-01-15 | Phenyl propanediol derivative, Preparation Method And The Use |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104529709A CN104529709A (en) | 2015-04-22 |
CN104529709B true CN104529709B (en) | 2016-02-24 |
Family
ID=52845395
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN201510021682.9A Active CN104529709B (en) | 2015-01-15 | 2015-01-15 | Phenyl propanediol derivative, Preparation Method And The Use |
Country Status (1)
Country | Link |
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CN (1) | CN104529709B (en) |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102757415B (en) * | 2011-04-25 | 2015-07-29 | 北京普禄德医药科技有限公司 | A kind of sodium dependent glucose transporter inhibitors and its production and use |
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2015
- 2015-01-15 CN CN201510021682.9A patent/CN104529709B/en active Active
Also Published As
Publication number | Publication date |
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CN104529709A (en) | 2015-04-22 |
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Legal Events
Date | Code | Title | Description |
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Class of derivative containing alcoxyl phenyl group and halogenated phenyl group propylene glycol and preparation method and application of class of derivative containing alcoxyl phenyl group and halogenated phenyl group propylene glycol Effective date of registration: 20170816 Granted publication date: 20160224 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20190604 Granted publication date: 20160224 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20190716 Address after: Room 505, Building C, 606 Ningliu Road, Changlu Street, Jiangbei New District, Nanjing City, Jiangsu Province, 210000 Patentee after: Nanjing Triumph Chemical Technology Co., Ltd. Address before: Chancheng district has 528000 Taiwan public in Guangdong province Foshan City No. 32 first floor 1636, shop No. 1637 Patentee before: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. |