CN104478671B - The two alkoxyphenyl radical propanediol derivative of one class and purposes - Google Patents
The two alkoxyphenyl radical propanediol derivative of one class and purposes Download PDFInfo
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- CN104478671B CN104478671B CN201510021521.XA CN201510021521A CN104478671B CN 104478671 B CN104478671 B CN 104478671B CN 201510021521 A CN201510021521 A CN 201510021521A CN 104478671 B CN104478671 B CN 104478671B
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- 0 *CNc1ccccc1 Chemical compound *CNc1ccccc1 0.000 description 1
- HHVKLSMQQJOXHF-UHFFFAOYSA-N CCOc1ccc(Cc2cc(CC(CO)O)ccc2OC)cc1 Chemical compound CCOc1ccc(Cc2cc(CC(CO)O)ccc2OC)cc1 HHVKLSMQQJOXHF-UHFFFAOYSA-N 0.000 description 1
- MNHMPECXVMOVDZ-SFHVURJKSA-N CCOc1ccc(Cc2cc(C[C@@H](CO)O)ccc2OCC)cc1 Chemical compound CCOc1ccc(Cc2cc(C[C@@H](CO)O)ccc2OCC)cc1 MNHMPECXVMOVDZ-SFHVURJKSA-N 0.000 description 1
Classifications
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Abstract
Description
Compound number | IC 50(hSGLT2,nM) |
Reference compound D-1 | 19.5 |
I-1 | 13.9 |
I-2 | 11.4 |
I-3 | 18.1 |
I-4 | 17.2 |
Claims (3)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
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CN201510021521.XA CN104478671B (en) | 2015-01-15 | 2015-01-15 | The two alkoxyphenyl radical propanediol derivative of one class and purposes |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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CN201510021521.XA CN104478671B (en) | 2015-01-15 | 2015-01-15 | The two alkoxyphenyl radical propanediol derivative of one class and purposes |
Publications (2)
Publication Number | Publication Date |
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CN104478671A CN104478671A (en) | 2015-04-01 |
CN104478671B true CN104478671B (en) | 2016-03-09 |
Family
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CN201510021521.XA Active CN104478671B (en) | 2015-01-15 | 2015-01-15 | The two alkoxyphenyl radical propanediol derivative of one class and purposes |
Country Status (1)
Country | Link |
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CN (1) | CN104478671B (en) |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103596564A (en) * | 2011-06-01 | 2014-02-19 | 株式会社绿十字 | Novel diphenylmethane derivatives as SGLT2 inhibitors |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2013152476A1 (en) * | 2012-04-10 | 2013-10-17 | Theracos, Inc. | Process for the preparation of benzylbenzene sglt2 inhibitors |
EP2925735B1 (en) * | 2012-11-20 | 2019-03-13 | Lexicon Pharmaceuticals, Inc. | Inhibitors of sodium glucose cotransporter 1 |
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2015
- 2015-01-15 CN CN201510021521.XA patent/CN104478671B/en active Active
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103596564A (en) * | 2011-06-01 | 2014-02-19 | 株式会社绿十字 | Novel diphenylmethane derivatives as SGLT2 inhibitors |
Non-Patent Citations (1)
Title |
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SGLT2 抑制剂Canagliflozin——Ⅱ型糖尿病治疗的新药;首要富等;《中国现代应用药学》;20140930;第31卷(第9期);第1154-1160页 * |
Also Published As
Publication number | Publication date |
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CN104478671A (en) | 2015-04-01 |
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Legal Events
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C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right | ||
PE01 | Entry into force of the registration of the contract for pledge of patent right |
Denomination of invention: Class of bis-alcoxyl phenyl group propylene glycol derivative and application of class of bis-alcoxyl phenyl group propylene glycol derivative Effective date of registration: 20170816 Granted publication date: 20160309 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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PC01 | Cancellation of the registration of the contract for pledge of patent right | ||
PC01 | Cancellation of the registration of the contract for pledge of patent right |
Date of cancellation: 20190604 Granted publication date: 20160309 Pledgee: Guangdong Nanhai Rural Commercial Bank branch branch of Limited by Share Ltd Pledgor: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. Registration number: 2017990000756 |
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TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20191016 Address after: 225321 No. 21 Gangcheng Road, Gaogang District, Taizhou City, Jiangsu Province Patentee after: Sun Jian Chun Address before: Chancheng district has 528000 Taiwan public in Guangdong province Foshan City No. 32 first floor 1636, shop No. 1637 Patentee before: FOSHAN SAIWEISI PHARMACEUTICAL TECHNOLOGY CO., LTD. |