CN104525065A - Bisphosphate microbial aerosol generator - Google Patents
Bisphosphate microbial aerosol generator Download PDFInfo
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- CN104525065A CN104525065A CN201410826305.8A CN201410826305A CN104525065A CN 104525065 A CN104525065 A CN 104525065A CN 201410826305 A CN201410826305 A CN 201410826305A CN 104525065 A CN104525065 A CN 104525065A
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- aerosol
- air
- microbial
- microbial aerosol
- bisphosphate
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/0095—Preparation of aerosols
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- Organic Chemistry (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a bisphosphate microbial aerosol generator. The bisphosphate microbial aerosol generator comprises an air compressor and an air storage tank, wherein the air compressor is connected with the air storage tank, and the air storage tank is connected with the air filter; a bisphosphate microorganism solution and a storage are connected with a liquid peristaltic pump, an air filter and the liquid peristaltic pump are connected with an aerodynamic sprayer and an aerosol generating device, and the aerodynamic sprayer and the aerosol generating device are connected with an aerosol recycling device; the air filter is also connected with an air rotor flow meter; the liquid peristaltic pump is also connected with a liquid flow meter; and the aerodynamic sprayer and the aerosol generating device are connected with a sampling controller. The bisphosphate microbial aerosol generator is applicable to simulated generation and preparation of experimental microbial aerosol and is frequently applied to preparation of a microbial aerosol animal model and research on microbial aerosol animal infection dosage, microbial aerosol survival recovery rate, an aerosol tracer agent, contrast between natural microbial aerosol and simulated microbial aerosol and the like.
Description
Technical field
The invention belongs to generation and the preparing technical field of microbial aerosol, be specially a kind of Diphosphonate microbial aerosol generating apparatus.
Background technology
Aerosol receives the concern of people day by day as one of focus in recent environmental problems.Although microbial aerosol is the component that in aerosol, content is little, more and more come into one's own because it plays an important role in many Aerosol Pollution processes.Microbial aerosol is that a group body is small, simply constructed unicellular or close to single celled biological suspension colloidal dispersion formed thereby in air, particle size, at 0.01 ~ 100 μm, is generally 0.1 ~ 30 μm.Microbial aerosol has 6 large characteristics: the heterogeneity in source, the diversity of kind, and active mutability, that sends out is three-dimensionality, the reproducibility of deposition, the popularity of infection.Microbial aerosol Carried bacteria, fungi (comprising fungal spore), virus, mycoplasma, Chlamydia and other microorganisms, mankind's various diseases can be caused, as various diseases such as various respiratory infectious disease, asthma, building syndromes under certain time and condition.Therefore, research causes communicable disease mechanism and mechanism etc. significant with the aerocolloidal concentration of monitoring air microbe, kind, distribution and Changing Pattern thereof and its.
At present, China mostly is investigation to the aerocolloidal research of air microbe, namely carries out air microbe sampling to certain place within a certain period of time, understands the situation such as concentration, kind of microorganism.But, research is further lacked for the route of transmission of microbial aerosol, Pathogenic Types, pathogenesis and mechanism.And study its mechanism of causing a disease and mechanism, need simulation preparation controllability microbial aerosol, set up reliable aerosol infection animal model.For this reason, the microbial aerosol needing the features such as a kind of controlled, stable, target badly is equipped.At present, mainly microbial aerosol sampler, the aerosol complexity of collection is various, active mutability, poor controllability, be difficult to meet experimental study needs.
Summary of the invention
The object of the present invention is to provide a kind of Diphosphonate microbial aerosol generator, comprise air compressor, air storage tank, air compressor is connected with air storage tank, and air storage tank connects air cleaner; Diphosphonate microbial solution and storage appts are connected with liquid peristaltic pump, and air cleaner is connected aerodynamic force shower nozzle and aerosol generating device with liquid peristaltic pump, and aerodynamic force shower nozzle and aerosol generating device connect aerosol recover.
Air cleaner is also connected with air robot flowmeter.
Liquid peristaltic pump is also connected with fluid flowmeter.
Aerodynamic force shower nozzle and aerosol generating device are connected with sampling controller.
The present invention is a kind of preparation and generating means of simulating microbial aerosol, makes the preparation of microbial aerosol and summary, procedure occur, having more controllability, stability and targeting.Further, the dissimilar microbial aerosol of preparation can be simulated as required.The present invention is usually used in the preparation of microbial aerosol animal model, the animal infected dosage of microbial aerosol, the rate of recovery of microbial aerosol survival, aerosol tracer, the research of the contrast of natural microbial aerosol and simulation microbial aerosol etc.For the aerocolloidal preparation of different microorganisms and generation, and its formation mechanism and in disease development effect there is directive significance.For preparing the animal model of certain specificity communicable disease, studying its pathogenesis and mechanism, providing a kind of novel feasible methods and direction, significant and broad prospect of application.
Accompanying drawing explanation
Accompanying drawing is structural representation of the present invention.
Below in conjunction with accompanying drawing, content of the present invention is described in further detail.
Detailed description of the invention
With reference to shown in accompanying drawing, comprise air compressor 1, air storage tank 2, air compressor 1 is connected with air storage tank 2, and air storage tank 2 connects air cleaner 3; Diphosphonate microbial solution and storage appts 5 are connected with liquid peristaltic pump 6, and air cleaner 3 is connected aerodynamic force shower nozzle and aerosol generating device 8 with liquid peristaltic pump 6, and aerodynamic force shower nozzle and aerosol generating device 8 connect aerosol recover 10.Air cleaner 3 is also connected with air robot flowmeter 4.
Liquid peristaltic pump 6 is also connected with fluid flowmeter 7.Aerodynamic force shower nozzle and aerosol generating device 8 are connected with sampling controller 9.
Air compressor 1 compressed air is also stored in air storage tank 2, is purified air by air cleaner 3, the flow of gas controlled by air robot flowmeter 4 or oxygen with high velocity air by thin bore nozzle.Prefabricated Diphosphonate solution is extracted out by liquid peristaltic pump 6, controls flow by thin bore nozzle with fluid flowmeter 7.Pure air and Diphosphonate microbial solution be mutual impingement mix in the chamber aerodynamic force shower nozzle and aerosol generator 8 of nozzle, the biphase gas and liquid flow that formation drop and air coexist.Change liquid-gas ratio, the particle size of droplet cluster can be controlled.Collide tiny droplet remaining in the receiver that falls back with ejection at a high speed by the interception of aerodynamic force spray nozzle, hit the particle fallen and be again atomized.Form aerosolized Diphosphonate microorganism liquid particulate in atmosphere, grain spectrum diameter is from 0.01 μm to 100 μm (being determined by different spray nozzles), and particle diameter is stablized, can be in atmosphere floating for a long time.Require to gather aerosol by microbial aerosol sampling controller root difference again, or be recovered in different aerosol recover.
Claims (4)
1. a Diphosphonate microbial aerosol generator, comprise air compressor (1), air storage tank (2), it is characterized in that, air compressor (1) is connected with air storage tank (2), and air storage tank (2) connects air cleaner (3); Diphosphonate microbial solution and storage appts (5) are connected with liquid peristaltic pump (6), air cleaner (3) is connected aerodynamic force shower nozzle and aerosol generating device (8) with liquid peristaltic pump (6), and aerodynamic force shower nozzle and aerosol generating device (8) connect aerosol recover (10).
2. Diphosphonate microbial aerosol generator according to claim 1, is characterized in that, air cleaner (3) is also connected with air robot flowmeter (4).
3. Diphosphonate microbial aerosol generator according to claim 1, is characterized in that, liquid peristaltic pump (6) is also connected with fluid flowmeter (7).
4. Diphosphonate microbial aerosol generator according to claim 1, is characterized in that, aerodynamic force shower nozzle and aerosol generating device (8) are connected with sampling controller (9).
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410826305.8A CN104525065A (en) | 2014-12-25 | 2014-12-25 | Bisphosphate microbial aerosol generator |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410826305.8A CN104525065A (en) | 2014-12-25 | 2014-12-25 | Bisphosphate microbial aerosol generator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104525065A true CN104525065A (en) | 2015-04-22 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN201410826305.8A Pending CN104525065A (en) | 2014-12-25 | 2014-12-25 | Bisphosphate microbial aerosol generator |
Country Status (1)
| Country | Link |
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| CN (1) | CN104525065A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104857901A (en) * | 2015-06-15 | 2015-08-26 | 华北电力大学（保定） | Microorganism aerosol generation device |
| CN105486624A (en) * | 2015-12-15 | 2016-04-13 | 江苏苏净集团有限公司 | Aerosol generating device |
| CN109266524A (en) * | 2018-09-21 | 2019-01-25 | 中国科学院生态环境研究中心 | A kind of closed micro-organism aerosol generating apparatus |
| CN110151793A (en) * | 2018-03-29 | 2019-08-23 | 中国人民解放军军事科学院军事医学研究院 | Plague bacillus liquid aersol lung delivers infecting mouse model |
| CN110252217A (en) * | 2019-06-20 | 2019-09-20 | 南京信息职业技术学院 | A kind of simulation aerosol generating device |
Citations (4)
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| US4917830A (en) * | 1988-09-19 | 1990-04-17 | The United States Of America As Represented By The United States Department Of Energy | Monodisperse aerosol generator |
| CN201193988Y (en) * | 2008-04-10 | 2009-02-11 | 中国建筑科学研究院 | Micro-organism aerosol generating apparatus |
| CN201568057U (en) * | 2009-11-26 | 2010-09-01 | 上海建工（集团）总公司 | Foam generating device for shield |
| CN202860509U (en) * | 2012-09-28 | 2013-04-10 | 青岛众瑞智能仪器有限公司 | DOP (Dioctyl-Phthalate) aerosol generator |
-
2014
- 2014-12-25 CN CN201410826305.8A patent/CN104525065A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4917830A (en) * | 1988-09-19 | 1990-04-17 | The United States Of America As Represented By The United States Department Of Energy | Monodisperse aerosol generator |
| CN201193988Y (en) * | 2008-04-10 | 2009-02-11 | 中国建筑科学研究院 | Micro-organism aerosol generating apparatus |
| CN201568057U (en) * | 2009-11-26 | 2010-09-01 | 上海建工（集团）总公司 | Foam generating device for shield |
| CN202860509U (en) * | 2012-09-28 | 2013-04-10 | 青岛众瑞智能仪器有限公司 | DOP (Dioctyl-Phthalate) aerosol generator |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104857901A (en) * | 2015-06-15 | 2015-08-26 | 华北电力大学（保定） | Microorganism aerosol generation device |
| CN104857901B (en) * | 2015-06-15 | 2017-03-22 | 华北电力大学（保定） | Microorganism aerosol generation device |
| CN105486624A (en) * | 2015-12-15 | 2016-04-13 | 江苏苏净集团有限公司 | Aerosol generating device |
| CN110151793A (en) * | 2018-03-29 | 2019-08-23 | 中国人民解放军军事科学院军事医学研究院 | Plague bacillus liquid aersol lung delivers infecting mouse model |
| CN109266524A (en) * | 2018-09-21 | 2019-01-25 | 中国科学院生态环境研究中心 | A kind of closed micro-organism aerosol generating apparatus |
| CN109266524B (en) * | 2018-09-21 | 2021-07-06 | 中国科学院生态环境研究中心 | Closed microorganism aerosol generating device |
| CN110252217A (en) * | 2019-06-20 | 2019-09-20 | 南京信息职业技术学院 | A kind of simulation aerosol generating device |
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Application publication date: 20150422 |