CN104524114A - Traditional Chinese medicine composition for treating non-estrous sows and preparation method - Google Patents
Traditional Chinese medicine composition for treating non-estrous sows and preparation method Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/894—Dioscoreaceae (Yam family)
- A61K36/8945—Dioscorea, e.g. yam, Chinese yam or water yam
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
- A61K36/296—Epimedium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/34—Campanulaceae (Bellflower family)
- A61K36/344—Codonopsis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
Abstract
The invention relates to a traditional Chinese medicine composition for treating non-estrous sows. The traditional Chinese medicine composition is prepared by Chinese yam, Chinese angelica, monkshood, cortex cinnamomi, herba epimedii, Chinese dates, codonopsis pilosula, astragalus membranaceus, root of common peony and moutan bark. The traditional Chinese medicine composition is powder. A traditional Chinese medicine composition preparation method includes the steps that (1) by weight, 10-16 parts of the Chinese yam, 10-15 parts of the Chinese angelica, 5-8 parts of the monkshood, 5-8 parts of the cortex cinnamomi, 15-20 parts of the herba epimedii, 5-8 parts of the Chinese dates, 10-15 parts of the codonopsis pilosula, 10-15 parts of the astragalus membranaceus, 3-10 parts of the roots of common peony and 4-8 parts of the moutan bark are weighed according to a formula; (2) the traditional Chinese medicine is smashed and screened through a screen with the mesh ranging from 40 to 100; (3) the traditional Chinese medicine is mixed for 5 minutes to 15 minutes, and traditional Chinese medicine powder is obtained; (4) every 100 g to 200 g of the traditional Chinese medicine powder is packaged per bag in a split mode, and finished products are obtained. The traditional Chinese medicine composition has the effects of warming the kidney and tonifying spleen, replenishing qi and enriching the blood, tonifying fire and helping yang and promoting estrus and ovulation. The traditional Chinese medicine composition is capable of effectively treating the non-estrous sows, and the curing rate reaches 96%.
Description
Technical field
The invention belongs to Chinese veterinary drug preparation field, especially a kind ofly treat Chinese medicine composition of sow non-estrus and preparation method thereof.
Background technology
Along with greatly developing of pig industry, the continuous introduction of external improved seeds and utilization and extention, the clinical manifestation of sow non-estrus problem is more and more outstanding.Sow non-estrus is a kind of important obstetric conditions, and it seriously governs the regenerative ratio of pig industry and the reduction of feeding cost, has become the bottleneck improving pig industry economic benefit.
Sow is once non-estrus, often more and more fertile, and the time is longer, promotes the sexual maturity and medicine is promoted the sexual maturity more insensitive to management.Therefore, carry out positive treatment to the sow of non-estrus to be very important.Cause the factor of sow non-estrus a lot, different Therapeutic Method need be adopted for different reasons.Conventional method is except employing nutrition regulation and stimulated in vitro method, and Drug therapy injects estrogen usually.After using hormone, oestrus of sow is exceedingly fast, often after intramuscular injection estrogen, several hours sows can show symptom of estrus, but sow only oestruses and does not ovulate, breed after oestrusing often failed, even if success, conception rate is also very low, only cherishes 1 ~ 3 son, and is repeatedly difficult to treatment by the disease such as ovarian cyst that can cause sow after estrogen.Although promote the sexual maturity oestrus of sow slowly with Chinese medicine, breeding easily success after oestrusing, conception rate is also high, cherishes young number between 10 ~ 19, and safety is safe, can not cause other diseases.Therefore, with treatment by Chinese herbs sow non-estrus, be worth research further.
Summary of the invention
The problem to be solved in the present invention is: overcome the deficiencies in the prior art, provides a kind of evident in efficacy, cure rate is high, side effect is low Chinese medicine composition.
Another technical problem that the present invention will solve is: provide a kind of Chinese medicine formula for the treatment of sow non-estrus.
Another technical problem that the present invention will solve is: the preparation method providing the powder of above-mentioned Chinese medicine composition.
For solving the problems of the technologies described above, the technical solution used in the present invention is: a kind of Chinese medicine composition for the treatment of sow non-estrus, is characterized in that: be prepared from by the raw material of following mass fraction: Rhizoma Dioscoreae 10-16 part, Radix Angelicae Sinensis 10-15 part, Radix Aconiti Lateralis Preparata 5-8 part, Cortex Cinnamomi 5-8 part, Herba Epimedii 15-20 part, Fructus Jujubae 5-8 part, Radix Codonopsis 10-15 part, Radix Astragali 10-15 part, Radix Paeoniae Rubra 5-10 part, Cortex Moutan 4-8 part.
Further, the mass fraction of the optimum feed stock of this Chinese medicine composition is as follows: Rhizoma Dioscoreae 16 parts, Radix Angelicae Sinensis 13 parts, Radix Aconiti Lateralis Preparata 8 parts, Cortex Cinnamomi 8 parts, Herba Epimedii 20 parts, 6 parts, Fructus Jujubae, Radix Codonopsis 10 parts, the Radix Astragali 10 parts, Radix Paeoniae Rubra 5 parts, Cortex Moutan 4 parts.
Further, this Chinese medicine composition is the various conventional extract oral medicine dosage form containing or do not contain pharmaceutic adjuvant.
Further, described preparation can be powder.
Further, the preparation method of the powder of said composition is:
(1) each Chinese medicine is taken by formula ratio, wherein, Rhizoma Dioscoreae 10-16 part, Radix Angelicae Sinensis 10-15 part, Radix Aconiti Lateralis Preparata 5-8 part, Cortex Cinnamomi 5-8 part, Herba Epimedii 15-20 part, Fructus Jujubae 5-8 part, Radix Codonopsis 10-15 part, Radix Astragali 10-15 part, Radix Paeoniae Rubra 5-10 part, Cortex Moutan 4-8 part; (2) Chinese medicine is pulverized, cross 40-100 mesh sieve; (3) mix 5-15 minute and obtain Chinese medicine powder; (4) Chinese medicine powder is got product by every bag of 100-200g subpackage.
The advantage that the present invention has and good effect are:
(1) this prescription is according to tcm theory, scientific compatibility, has invigorating kidney qi, promoting flow of QI and blood, the fiery supporing yang effect of benefit, through clinical verification determined curative effect, cure rate can reach more than 96%, solves and needs clinically to use hormone to promote oestrus of sow, the defect that side effect is large.The Chinese medicine preparation simultaneously obtained according to this prescription have evident in efficacy, side effect is low, the advantage of environmental protection.
(2) pharmacology of each raw material of Chinese medicine of the present invention is:
Rhizoma Dioscoreae: supplementing QI and nourishing YIN, spleen reinforcing lung kidney, treating spontaneous emission and leukorrhagia;
Radix Angelicae Sinensis: tonifying blood and regulating menstruation, promoting blood circulation and stopping pain, loosening bowel to relieve constipation;
Radix Aconiti Lateralis Preparata: recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, dispersing cold for relieving pain;
Cortex Cinnamomi: mend fire supporing yang, dispersing cold for relieving pain, promoting the flow of QI-blood by warming the meridian, conducting fire back to its origin;
Herba Epimedii: kidney invigorating and YANG supporting, expelling wind and removing dampness;
Fructus Jujubae: invigorating the spleen and replenishing QI, nourishing blood to tranquillize the mind;
Radix Codonopsis: spleen reinforcing lung qi, enriches blood, promotes the production of body fluid;
The Radix Astragali: air making-up and spleen enlivening, ascending up spleen-Qi and Yang, benefit defends consolidating superficial resistance;
Radix Paeoniae Rubra: nourish blood yin fluid astringing, easing the affected liver to relieve pain, suppressing liver-YANG;
Cortex Moutan: blood circulation promoting and blood stasis dispelling.
According to the viewpoint of Chinese veterinarian, sow non-estrus be because the sexual function that causes of spleen, insufficiency of kidney-YANG inharmonious, decline, invigorate blood circulation spleen reinforcing, kidney yang of the rule for the treatment of is promoted the sexual maturity.Among formula, Rhizoma Dioscoreae nature and flavor are sweet flat, can invigorating the spleen and replenishing QI, and it is cloudy to nourish spleen, again can the kidney invigorating gas, doublely can nourish kidney yin.Herba Epimedii is pungent sweet warm in nature dry strong, is longer than kidney invigorating and YANG supporting, for treating key medicine of suffering from a deficiency of the kidney.Kidney is sky basis, and kidney qi is prosperous, expedites the emergence of the normal function of each genitals such as ovary and uterus, reaches rutting on time.The Radix Astragali, Radix Codonopsis, Fructus Jujubae is separately had to be the medicine of invigorating the spleen and replenishing QI; Radix Angelicae Sinensis, Cortex Moutan, Radix Paeoniae Rubra nourishing blood and promoting blood circulation, sweet Wen Zhirun is conventional medicine of enriching blood.Enrich blood and need QI invigorating, spleen is source of generating QI and blood, and blood deficiency comes from insufficiency of the spleen, therefore enrich blood medicine and spleen reinforcing drug combination, sow blood circulation can be made to keep unimpeded, vigorous, physical strength reinforcing, recover the function ovulation rate of sow reproduction body.There is Radix Aconiti Lateralis Preparata pungent sweet warm again, high complement sun; Cortex Cinnamomi is also the thing of pungent sweet large heat, can mend fire supporing yang, Radix Aconiti Lateralis Preparata and Cortex Cinnamomi compatibility sexual impotence spermatorrhea, the infertility of controlling insufficiency of kidney-YANG decline of the fire from the gate of life, can add the conceived probability of sow, improve farrowing amount.Above-mentioned ten taste medicine compatibilities use, can reinforcing spleen and kidney, promoting flow of QI and blood, benefit fire is supporing yang, thus promote oestrus of sow, increase farrowing probability.
Detailed description of the invention
Be further described the present invention below by specific embodiment, following examples are descriptive, are not determinate, can not limit protection scope of the present invention with this.
Embodiment 1
Treat a Chinese powder medicine for sow non-estrus, the parts by weight of each raw material are as follows: Rhizoma Dioscoreae 16 parts, Radix Angelicae Sinensis 13 parts, Radix Aconiti Lateralis Preparata 8 parts, Cortex Cinnamomi 8 parts, Herba Epimedii 20 parts, 6 parts, Fructus Jujubae, Radix Codonopsis 10 parts, the Radix Astragali 10 parts, Radix Paeoniae Rubra 5 parts, Cortex Moutan 4 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mix 10 minutes and obtain Chinese medicine powder; (4) Chinese medicine powder is pressed every bag of 200g subpackage, get product.
Embodiment 2
Treat a Chinese powder medicine for sow non-estrus, the parts by weight of each raw material are as follows: Rhizoma Dioscoreae 12 parts, Radix Angelicae Sinensis 10 parts, Radix Aconiti Lateralis Preparata 5 parts, Cortex Cinnamomi 5 parts, Herba Epimedii 15 parts, 5 parts, Fructus Jujubae, Radix Codonopsis 15 parts, the Radix Astragali 15 parts, Radix Paeoniae Rubra 10 parts, Cortex Moutan 8 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mix 10 minutes and obtain Chinese medicine powder; (4) Chinese medicine powder is pressed every bag of 200g subpackage, get product.
Embodiment 3
Treat a Chinese powder medicine for sow non-estrus, the parts by weight of each raw material are as follows: Rhizoma Dioscoreae 10 parts, Radix Angelicae Sinensis 15 parts, Radix Aconiti Lateralis Preparata 6 parts, Cortex Cinnamomi 7 parts, Herba Epimedii 18 parts, 8 parts, Fructus Jujubae, Radix Codonopsis 13 parts, the Radix Astragali 12 parts, Radix Paeoniae Rubra 6 parts, Cortex Moutan 5 parts are prepared from.Its preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized, cross 60 mesh sieves; (3) mix 10 minutes and obtain Chinese medicine powder; (4) Chinese medicine powder is pressed every bag of 200g subpackage, get product.
Clinical trial
Experiment 1:
Henan Province villager Wang, a black sow of raising, farrowing wean is oestrused latter two moon not yet.Find that this sow body constitution is thin and weak on inspection, appetite is normal, and labia reacts without redness, and pale tongue is white, touches and presses waist, show without recessed waist, boar examination feelings, asexual wish.Feed with medicine spice obtained in embodiment 1, spice ratio is every 200g spice 100kg feedstuff.One day twice, connect and feed 20 days.Drug withdrawal is oestrus of sow after 2 days, and breeding is become pregnant successfully.
Test 1 result and show that the Chinese powder medicine treatment sow non-estrus of use obtained by the present invention is evident in efficacy.
Experiment 2
Pig farm, Hebei province, about wherein having 18 8 monthly ages, white replacement gilt is not oestrused always, separately has more than 15 Suprapubic arch sling farrowing wean March and oestruses not yet.Then feed with the Chinese powder medicine spice obtained by the embodiment of the present invention 1.Spice ratio is every 200g spice 100kg feedstuff.One day twice, connect and feed 20.Except a sow non-estrus, all oestrus after all the other 32 sow medications, and breeding is become pregnant successfully.
Test 2 results to show, use the Chinese powder medicine treatment sow non-estrus obtained by the present invention, evident in efficacy, clinical effective rate can reach more than 96%, and there is not the untoward reaction of Western medicine, is worth promoting the use of clinically.
The above, be only preferred embodiments of the present invention, is illustrative instead of determinate, can list several embodiments according to limited range, therefore in the change do not departed under general plotting of the present invention and amendment, should belong within protection scope of the present invention.
Claims (8)
1. one kind is used for the treatment of the Chinese medicine composition of sow non-estrus, it is characterized in that, be prepared from by the raw material of following mass fraction: Rhizoma Dioscoreae 10-16 part, Radix Angelicae Sinensis 10-15 part, Radix Aconiti Lateralis Preparata 5-8 part, Cortex Cinnamomi 5-8 part, Herba Epimedii 15-20 part, Fructus Jujubae 5-8 part, Radix Codonopsis 10-15 part, Radix Astragali 10-15 part, Radix Paeoniae Rubra 5-10 part, Cortex Moutan 4-8 part.
2. the Chinese medicine composition for the treatment of sow non-estrus according to claim 1, is characterized in that: the mass fraction of optimum feed stock is as follows:
Rhizoma Dioscoreae 16 parts, Radix Angelicae Sinensis 13 parts, Radix Aconiti Lateralis Preparata 8 parts, Cortex Cinnamomi 8 parts, Herba Epimedii 20 parts, 6 parts, Fructus Jujubae, Radix Codonopsis 10 parts, the Radix Astragali 10 parts, Radix Paeoniae Rubra 5 parts, Cortex Moutan 4 parts.
3. the Chinese medicine composition for the treatment of sow non-estrus according to claim 1 and 2, is characterized in that: this Chinese medicine composition is the various conventional extract oral medicine dosage form containing or do not contain pharmaceutic adjuvant.
4. the Chinese medicine composition for the treatment of sow non-estrus according to claim 3, is characterized in that: described preparation can be powder.
5. prepare a method for the Chinese medicine composition for the treatment of sow non-estrus as claimed in claim 4, it is characterized in that, preparation method is: (1) takes each Chinese medicine by formula ratio; (2) Chinese medicine is pulverized and sieved; (3) Chinese medicine powder is mixed; (4) subpackage gets product.
6. the preparation method of the Chinese medicine composition for the treatment of sow non-estrus according to claim 5, is characterized in that: Chinese medicine is pulverized as 40-100 order.
7. the preparation method of the Chinese medicine composition for the treatment of sow non-estrus according to claim 5, is characterized in that: Chinese medicine powder incorporation time is 5-15 minute.
8. the preparation method of the Chinese medicine composition for the treatment of sow non-estrus according to claim 5, is characterized in that: packing specification is 100-200g/ bag.
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CN105943600A (en) * | 2016-06-27 | 2016-09-21 | 烟台海研制药有限公司 | Traditional Chinese medicine composition for treating sows showing no estrus |
CN105995086A (en) * | 2016-05-27 | 2016-10-12 | 垫江县国英生猪养殖场 | Feed additive capable of increasing farrowing quantity of sows |
CN106071194A (en) * | 2016-06-08 | 2016-11-09 | 詹中伦 | A kind of feed additive improving sows farrowing amount |
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105995086A (en) * | 2016-05-27 | 2016-10-12 | 垫江县国英生猪养殖场 | Feed additive capable of increasing farrowing quantity of sows |
CN106071194A (en) * | 2016-06-08 | 2016-11-09 | 詹中伦 | A kind of feed additive improving sows farrowing amount |
CN105943600A (en) * | 2016-06-27 | 2016-09-21 | 烟台海研制药有限公司 | Traditional Chinese medicine composition for treating sows showing no estrus |
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