CN104509855A - Auxiliary hypoglycemic composition and preparation method thereof - Google Patents
Auxiliary hypoglycemic composition and preparation method thereof Download PDFInfo
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Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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- Medicines Containing Plant Substances (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
The invention discloses an auxiliary hypoglycemic composition, preparation method and application thereof to preparation of hypoglycemic health food, and belongs to the field of health food. The auxiliary hypoglycemic composition disclosed by the invention mainly consists of the following eight medicinal materials: Astragalus membranaceus, Chinese yam, Radix Codonopsis, the root of kudzu vine, ophiopogon root, rhizoma anemarrhenae, Chinese angelica and rose. The composition has clear hypoglycemic function, is suitable for people with high blood sugar, and can improve the immunity of patients with diabetes. Therefore, the composition can be used as health food for long-term usage, and is suitable for adjuvant treatment of diabetes.
Description
Technical field
The present invention relates to a kind of can the composition of auxiliary hyperglycemic, and the preparation method of said composition and preparing the application in hypoglycemia healthcare food, belongs to field of health care food.
Background technology
Diabetes (DM) are one of modal epidemic diseases of world wide, have become the disease of the third-largest serious threat human health after cardiovascular, tumour.Along with the change of the raising of people's living standard, the aging of population and resident living mode, diabetes prevalence is in rising trend.About there are 1.5 hundred million diabetics in the current whole world, predicts 2025 and will be increased to 300,000,000.
The prevention of DM is one of world's public health difficult problem.The complication such as diabetes and diabetic nephropathies, ephrosis, vascular lesion, DPN not only threaten health and the life of people, reduce quality of life, bring serious financial burden especially.Diabetes are a kind of general chronic diseases, cannot effect a radical cure at present, so no matter which kind of type it belongs to, state of an illness weight how, with or without complication, whether with insulin or oral hypoglycemic drug therapy, all must strict implement and adhere to diet control for a long time, psychological regulation, motion exercise, the methods such as traditional medicine, carry out nursing and keeping healthy energetically.The health products of auxiliary hyperglycemic, because of the function factor contained by it, have assisting patients and reduce blood sugar, improve illness, promote the effect of body function.
The therapeutic scheme of current diabetes, dietetic treatment is all extremely praised highly in countries in the world, emphasizes the importance of dietetic treatment energetically, emphasizes the wholistic therapy scheme of routing motion treatment, drug therapy etc. on dietetic treatment basis.In addition, due to diabetes all the life can not the reason such as side effect of healing property and drug resistance, the resistance to the action of a drug and medicine, diabetes patient is very large to the demand of hypoglycemic health-care product.
Chinese herbal medicine has remarkable effect, the health-care efficacy of measure in succession for playing traditional Chinese medicine that herbal cuisine etc. are new preventing and treating in the various chronic complicating diseases of diabetes, improves this illness to can quantitatively keep healthy for a long time, and exploitation auxiliary hyperglycemic health products are very valuable.
This assistant hypoglycemia healthcare food formulation manipulation to combine prescription according to Traditional Chinese medical theory and modern scientific research achievement.In this Ricipe for health care food: the Radix Astragali, sweet in flavor and warm in property, tonifying middle-Jiao and Qi; Radix Codonopsis, air making-up and spleen enlivening; Radix Angelicae Sinensis, nourshing blood and promoting blood circulation, association's Radix Codonopsis, the Radix Astragali, with benefiting qi and nourishing blood, Chinese yam, have supplementing qi and nourishing yin, effect of tonifying speen and tonifying kidney, nourishing Yin and clearing heatly can treat diabetes, the root of kudzu vine, Gan Xinping, except dysphoria with smothery sensation, promote the production of body fluid to quench thirst; The tuber of dwarf lilyturf, enriching yin; Wind-weed heat-clearing and enriching yin is not enough, joins nutrient solution of promoting the production of body fluid the tuber of dwarf lilyturf, moisturizes and quench the thirst.Rose has promotes longevity, effect of the promoting flow of qi and blood circulation, and its extract significantly can reduce type II diabetes rat blood sugar level, and adjusting blood lipid is abnormal.Therefore this assistant hypoglycemia healthcare food be by: the extract of the Radix Astragali, Radix Codonopsis, Chinese yam, Radix Angelicae Sinensis, the root of kudzu vine, the wind-weed, the tuber of dwarf lilyturf, rose, preparation, takes.
The function of blood sugar reduction factor has: flavonoids, glycitols, saponins, dietary fiber class (water-soluble), polysaccharide, thioether class, amino acids, trace element and vitamin, unrighted acid etc.The mixed extract of the Radix Astragali, Radix Codonopsis, Chinese yam, Radix Angelicae Sinensis, the root of kudzu vine, the wind-weed, the tuber of dwarf lilyturf, rose is had in this formula for a product, astragalus polyose, Codonopsis pilosula polysaccharide, ophiopogonpolysaccharide, anemaran, Chinese yam polysaccharide etc. are all polysaccharides, and water extraction completely can these active components of cost-effective acquisition, in addition the saponins compound such as astragaloside, timosaponin is also had, also has the flavonoids such as rose flavone, kudzu root flavone active component, these are all hypoglycemic function factors, and the hypoglycemic function of this product has modern compatibility theory foundation.
Beneficial effect of the present invention is:
1, of the present invention can auxiliary hyperglycemic composition safety, effectively, cost is low;
2, of the present invention can the composition extraction process simple (water extraction, concentrated) of auxiliary hyperglycemic, preparation process stable and simple (dry, grinding, sieves).
3, the present invention can auxiliary hyperglycemic composition preparation in do not use organic reagent, it is Chinese medicinal plant the water extracted immersing paste, composition scientific formula of the present invention is reasonable, there is clear and definite function of blood sugar reduction, be applicable to the crowd of high blood glucose, the immunity of diabetes patient can be improved, and safety, toxic and side effect be low simultaneously, be a kind of can the health food of long-term taking, be applicable to the supplemental treatment of diabetes.
Therefore, disclosed by the invention can auxiliary hyperglycemic composition can preparation hypoglycemic health food in apply.
Summary of the invention
The object of the invention be to provide a kind of can the composition and method of making the same of auxiliary hyperglycemic, another object of the present invention is to provide a kind ofly the composition of auxiliary hyperglycemic can prepare the application in health-caring product capable of reducing blood sugar, described the composition of auxiliary hyperglycemic can comprise following 8 taste medicinal materials: the Radix Astragali, Chinese yam, Radix Codonopsis, the root of kudzu vine, the tuber of dwarf lilyturf, the wind-weed, Radix Angelicae Sinensis, rose.
Wherein, said composition by weight: the Radix Astragali is 15-20, and Chinese yam is 15-20, and Radix Codonopsis is 10-15, and the root of kudzu vine is 6-10, and the tuber of dwarf lilyturf is 6-10, and the wind-weed is 6-9, and when being classified as 6-12, rose is 3-4.
Wherein, can select, the Radix Astragali is 15, and Chinese yam is 15, and Radix Codonopsis is 10, and the root of kudzu vine is 6, and the tuber of dwarf lilyturf is 6, and the wind-weed is 6, and when being classified as 6, rose is 3.
Wherein, can select, said composition by weight: the Radix Astragali is 18, and Chinese yam is 18, and Radix Codonopsis is 13, and the root of kudzu vine is 8, and the tuber of dwarf lilyturf is 8, and the wind-weed is 8, and when being classified as 9, rose is 4.
Wherein, can select, said composition by weight: the Radix Astragali is 20, and Chinese yam is 20, and Radix Codonopsis is 15, and the root of kudzu vine is 10, and the tuber of dwarf lilyturf is 10, and the wind-weed is 9, and when being classified as 12, rose is 4.
This Chinese medicine composition is powder, pill, granule, capsule, tablet as the pharmaceutical preparation of active component.
Preparing can the method for composition of auxiliary hyperglycemic, comprises the steps:
(1) take the Radix Astragali, Chinese yam, Radix Codonopsis, the root of kudzu vine, the tuber of dwarf lilyturf, the wind-weed, Radix Angelicae Sinensis, rose respectively in proportion, removing foreign material, clean, dry;
(2) by the Radix Astragali, Chinese yam, Radix Codonopsis, the root of kudzu vine, the tuber of dwarf lilyturf, the wind-weed, Radix Angelicae Sinensis, rose, put in refluxing extraction device, add 10 times of water gaging refluxing extraction 2 hours, filter to obtain supernatant, the dregs of a decoction add 8 times of water refluxing extraction 1.5 hours again, merge extracted twice liquid, be separated to obtain supernatant, supernatant concentration is become thick paste.
Wherein, described thick paste, at 70 DEG C, after dry, pulverize, is crossed 100 mesh sieves and is obtained fine powder under 0.8Mpa condition.
The invention also discloses a kind of can auxiliary hyperglycemic composition preparation hypoglycemic health food in application.
Detailed description of the invention
Below in conjunction with specific embodiment, technical scheme of the present invention is described in further detail, but protection scope of the present invention is not limited to the following stated.
Embodiment 1 can the preparation of composition of auxiliary hyperglycemic
1, material: Radix Astragali medicine materical crude slice, Chinese yam medicine materical crude slice, Radix Codonopsis medicine materical crude slice, root of kudzu vine medicine materical crude slice, the tuber of dwarf lilyturf medicine materical crude slice, wind-weed medicine materical crude slice, angelica sinensis, rose medicine materical crude slice, all purchased from the Lanzhou chain Co., Ltd of Hui Rentang medicine company.
2, can the composite formula of auxiliary hyperglycemic
(1) 1 is filled a prescription:
Said composition is by weight: the Radix Astragali is 15, and Chinese yam is 15, and Radix Codonopsis is 10, and the root of kudzu vine is 6, and the tuber of dwarf lilyturf is 6, and the wind-weed is 6, and when being classified as 6, rose is 3.
(2) 2 are filled a prescription:
Said composition is by weight: the Radix Astragali is 15, and Chinese yam is 20, and Radix Codonopsis is 10, and the root of kudzu vine is 6, and the tuber of dwarf lilyturf is 6, and the wind-weed is 6, and when being classified as 6, rose is 3.
(3) 3 are filled a prescription:
Said composition is by weight: the Radix Astragali is 15, and Chinese yam is 15, and Radix Codonopsis is 15, and the root of kudzu vine is 10, and the tuber of dwarf lilyturf is 6, and the wind-weed is 6, and when being classified as 6, rose is 3.
(4) 4 are filled a prescription:
Said composition is by weight: the Radix Astragali is 18, and Chinese yam is 18, and Radix Codonopsis is 13, and the root of kudzu vine is 8, and the tuber of dwarf lilyturf is 8, and the wind-weed is 8, and when being classified as 9, rose is 4.
(5) 5 are filled a prescription:
Said composition is by weight: the Radix Astragali is 20, and Chinese yam is 15, and Radix Codonopsis is 10, and the root of kudzu vine is 10, and the tuber of dwarf lilyturf is 10, and the wind-weed is 9, and when being classified as 12, rose is 4.
(6) 6 are filled a prescription:
Said composition is by weight: the Radix Astragali is 20, and Chinese yam is 20, and Radix Codonopsis is 15, and the root of kudzu vine is 10, and the tuber of dwarf lilyturf is 10, and the wind-weed is 9, and when being classified as 12, rose is 4.
3, preparation method
(1) take the Radix Astragali, Chinese yam, Radix Codonopsis, the root of kudzu vine, the wind-weed, the tuber of dwarf lilyturf, Radix Angelicae Sinensis, rose respectively in proportion, removing foreign material, clean, dry;
(2) by the Radix Astragali, Chinese yam, Radix Codonopsis, the root of kudzu vine, the tuber of dwarf lilyturf, the wind-weed, Radix Angelicae Sinensis, rose, put in refluxing extraction device, add 10 times of water gaging refluxing extraction 2 hours, filter to obtain supernatant, the dregs of a decoction add 8 times of water refluxing extraction 1.5 hours again, merge extracted twice liquid, be separated to obtain supernatant, supernatant concentration is become thick paste.Thick paste, at 70 DEG C, after dry, pulverize, is crossed 100 mesh sieves and is obtained fine powder under 0.8Mpa condition.
This Chinese medicine composition is powder, pill, granule, capsule, tablet as the pharmaceutical preparation of active component.
Embodiment 2 can auxiliary hyperglycemic composition auxiliary hyperglycemic efficacy assessments experiment
1, reagent
(1) the present embodiment is used can the composition of auxiliary hyperglycemic be fill a prescription 6, the product prepared according to embodiment 1 method therefor according in embodiment one.
(2) alloxan (sigma company), for manufacturing zoic model with hyperglycemia medicine used.
2, animal used as test:
Female cleaning grade kunming mice, purchased from Lanzhou University GLP Experimental Base animal center (authentication code SCXK (sweet) 2013-0002), body weight 26.0 ± 2.0g; Wherein 110 animals manufacture hyperglycemia model, and after modeling screening, for the impact of working sample on hyperglycemia model animal blood glucose, 30 animals are used for sample to normal animal blood glucose impact experiment.
3, key instrument, equipment:
Electronic balance (0.0001g), blood sugar kit (company is built up in Nanjing), ELIASA.4, experimental technique
(1) zoic model with hyperglycemia made by alloxan: after mouse fasting 24h, tail vein injection alloxan (48mg/kg. presses batheroom scale), fasting 5 hours after 7 days, surveys fasting blood sugar, and blood glucose value 10 ~ 25mmol/L is hyperglycemia model success animal.
(2) dosage choice: according to human oral's recommended amounts, if the present invention can be respectively to mouse stomach by batheroom scale by auxiliary hyperglycemic composition: low dose group mouse 0.2g/kg, middle dosage group mouse 0.40g/kg, high dose group mouse 1.20g/kg (being equivalent to 5,10,30 times of human body recommended amounts respectively).Every day gavage once, gavage volume is 0.2ml/10g, and control group gives isopyknic distilled water, continuous 30 days.
(3) sample preparation: get can auxiliary hyperglycemic composition 2.00g, 4.00g, 12.00g adding distil water to 200ml, be made into basic, normal, high dosage desired concn, i.e. low dosage 0.01g/ml, middle dosage 0.02g/ml, high dose 0.06g/ml.
4, Data Processing in Experiment: carry out data transformations and statistical analysis with Excel, Spss software.When comparing by Spss software statistics, first homogeneity test of variance is carried out to data, if variance is neat, adopts one-way analysis of variance totally to compare, then carry out comparing between two between multiple dosage group with a control group mean by Dunnett method.If heterogeneity of variance, then suitable variable transitions is carried out to initial data, after meeting homogeneity test of variance, add up by the data after conversion; If do not reach the neat object of variance after variable transitions yet, use rank test instead and add up, find overall more variant, then adopt and do not require that Tamhane ' the s T2 of homogeneity of variance inspection is compared between two.
Result judges: according to foundation " health food inspection and assessment technical specification " version in 2003, an index positive in fasting blood-glucose and sugar tolerance binomial index, and on intact animal fasting blood-glucose without impact, can judge that this given the test agent auxiliary hyperglycemic function results of animal is positive.
5, fasting blood-glucose experiment is reduced
(1) intact animal: 30 mouse, by the grouping of the fasting blood sugar level of 5 hours, are divided into 1 control group and 1 given the test agent group (high dose group) at random.High dose group gives by test solution (high dose 0.06g/ml), and control group gives equal-volume distilled water, continuous 30 days, and fasting surveys fasting blood sugar, more each treated animal blood glucose value and blood sugar decline percentage in 5 hours.Blood glucose value × 100% before blood sugar decline percentage=(before experiment the rear blood glucose value of blood glucose value-experiment)/experiment.
Table 1 can the composition of auxiliary hyperglycemic on the impact (x ± s, n=10) of normal Mouse Weight
| Group | Number of animals (only) | Original body mass (g) | Body weight in mid-term (g) | Body weight in latter stage (g) |
| Control group | 15 | 26.5±3.7 | 32.3±3.6 | 33.8±2.3 |
| High dose group | 15 | 25.8±2.8 | 31.9±2.0 | 32.8±2.9 |
From table 1, per os gives normal mouse high dose content of the present invention 30 days, does not affect (P > 0.05) the body weight of mouse.
Table 2 can the composition of auxiliary hyperglycemic on the impact of normal mouse fasting blood-glucose
From table 2, per os gives normal mouse high dose content of the present invention 30 days, and the fasting blood sugar of mouse does not reduce (P > 0.05).Illustrate that the present invention is little on normal mouse blood sugar level impact, more can not cause hypoglycemia.
(2) hyperglycemia model animal: select hyperglycemia model success animal 70, be divided into a model control group and three dosage groups (group difference is less than 0.1mmol/L) at random.Dosage group gives variable concentrations by test solution, and model control group gives equal-volume distilled water, continuous 30 days, and fasting surveys fasting blood sugar, more each treated animal blood glucose value and blood sugar decline percentage in 5 hours.
Blood glucose value × 100% before blood sugar decline percentage=(before experiment the rear blood glucose value of blood glucose value-experiment)/experiment.
Table 3 can the composition of auxiliary hyperglycemic on the impact (x ± s, n=10) of hyperglycemia model Mouse Weight
| Group | Number of animals (only) | Original body mass (g) | Body weight in mid-term (g) | Body weight in latter stage (g) |
| Control group | 15 | 26.5±3.7 | 24.6±2.7 | 27.1±2.9 |
| Low dose group | 15 | 27.0±5.1 | 22.0±2.0 | 26.7±2.4 |
| Middle dosage group | 15 | 24.9±4.8 | 23.1±2.7 | 25.9±3.1 |
| High dose group | 15 | 24.5±5.2 | 26.1±4.3 | 27.3±2.4 |
From table 3, per os gives the content of the present invention 30 days of mouse various dose, and the changes of weight of each dosage group on mouse does not affect (P > 0.05).
Table 4 can the composition of auxiliary hyperglycemic on the impact of hyperglycemia model mouse fasting blood-glucose
From table 4, per os gives the content of the present invention 30 days of mouse various dose, property (P < 0.05) that high dose group mouse fasting blood-glucose measured value compares with control group that there were significant differences, the present invention can reduce mouse fasting blood sugar.
6, sugar tolerance experiment
Hyperglycemia model success animal fasting 5 hours, dosage group gives variable concentrations by test solution, model control group gives equal-volume distilled water, glucose 2.0g/kg is given through mouth by batheroom scale after 15 ~ 20 minutes, measure to the blood glucose value of glucose after 0,0.5,2 hour, the change of each time point Area under the curve of blood glucose after observing and nursing control group and given the test agent group give glucose.
Area under the curve of blood glucose=0.25 × (0 hours blood glucose value+4 × 0.5 hours blood glucose value+3 × 2 hours blood glucose value).
Table 5 can the composition of auxiliary hyperglycemic on the impact of hyperglycemia model animal sugar tolerance
From table 5, said composition can reduce mouse postprandial blood sugar, oral administration of glucose 0.5h, and during 2h, the blood glucose value of high dose mouse lower than model control group, and has significant difference; Can strengthen the glucose load sugar tolerance of mouse, compare with model control group, Area under the curve of blood glucose reduces significant difference (P < 0.05).
7, conclusion
Under the present embodiment experiment condition, give the content of the present invention 30 days of mouse 0.20g/kg, 0.40g/kg, 1.20g/kg dosage by batheroom scale per os.The present composition can reduce hyperglycemia model mouse fasting blood sugar, compares with hyperglycemia model control group, and high dose group mouse blood sugar decline percentage increases, and difference has conspicuousness (P < 0.05); Can improve glucose tolerance in mice, compare with hyperglycemia model control group, high dose group mouse blood sugar TG-AUC reduces, and difference has conspicuousness (P < 0.05).Normal mouse fasting blood-glucose is had no significant effect (P > 0.05).Can judge according to according to " health food inspection and assessment technical specification " version in 2003, the present invention has auxiliary hyperglycemic function to animal.
Embodiment 3 can the composition of auxiliary hyperglycemic affect the immunity of diabetic mice
By hyperglycemia model control group mice and blank group mouse, by batheroom scale, low dose group per os gives mouse 0.20g/kg, high dose group its mouse oral gives 1.20g/kg, hyperglycemia model control group gives distilled water, often organizes 10, gets Thymus and spleen respectively, weigh, calculate thymus index and index and spleen index.
Thymus index=thymus gland average weight (mg)/average mice body weight (g)
Index and spleen index=spleen average weight (mg)/average mice body weight (g)
Table 6 can the composition of auxiliary hyperglycemic on the impact of hyperglycemia model animal thymus index
From table 6, after alloxan modeling, model control group compares with blank group, the thymus index of mouse reduces, there is significant difference (P < 0.05), per os gives mouse various dose content of the present invention 30 days, and high dose group mouse thymus index compares with model control group significant difference (P < 0.05).
Table 7 can the composition of auxiliary hyperglycemic on the impact of hyperglycemia model animal spleen index
From table 7, after alloxan modeling, model control group compares with blank group, the index and spleen index of mouse reduces, there is no significant difference (P > 0.05), per os gives mouse various dose content of the present invention 30 days, and high dose group mouse spleen index compares with model control group does not have significant difference (P > 0.05).
Under this experiment condition, raise after 30 days, model control group thymus index compares with blank, there is significant difference (P < 0.05), model control group index and spleen index compares with blank group does not have significant difference (P > 0.05), the content of the present invention 30 days of mouse 1.20g/kg high dose is given by batheroom scale per os, high dose group hyperglycemia model mouse thymus index compares to have with control group and increases, and difference has conspicuousness (P < 0.05); Hyperglycemia model mouse spleen index is had no significant effect (P > 0.05).Because diabetes can suppress the growth of mouse thymus, spleen, produce infringement to immune function of mice, the present invention can strengthen the function of diabetic mice partial immunity organ as can be seen from the above results, thus improves diabetic mice non-specific immune function.
Claims (8)
1. one kind can the composition of auxiliary hyperglycemic, it is characterized in that, this can the composition of auxiliary hyperglycemic comprise: the Radix Astragali, Chinese yam, Radix Codonopsis, the root of kudzu vine, the tuber of dwarf lilyturf, the wind-weed, Radix Angelicae Sinensis, rose, said composition by weight: the Radix Astragali is 15-20, and Chinese yam is 15-20, Radix Codonopsis is 10-15, the root of kudzu vine is 6-10, and the tuber of dwarf lilyturf is 6-10, and the wind-weed is 6-9, when being classified as 6-12, rose is 3-4.
2. a kind of as claimed in claim 1 can the composition of auxiliary hyperglycemic, it is characterized in that, said composition by weight: the Radix Astragali is 15, and Chinese yam is 15, and Radix Codonopsis is 10, and the root of kudzu vine is 6, and the tuber of dwarf lilyturf is 6, and the wind-weed is 6, and when being classified as 6, rose is 3.
3. a kind of as claimed in claim 1 can the composition of auxiliary hyperglycemic, it is characterized in that, said composition by weight: the Radix Astragali is 18, and Chinese yam is 18, and Radix Codonopsis is 13, and the root of kudzu vine is 8, and the tuber of dwarf lilyturf is 8, and the wind-weed is 8, and when being classified as 9, rose is 4.
4. a kind of as claimed in claim 1 can the composition of auxiliary hyperglycemic, it is characterized in that, said composition by weight: the Radix Astragali is 20, and Chinese yam is 20, and Radix Codonopsis is 15, and the root of kudzu vine is 10, and the tuber of dwarf lilyturf is 10, and the wind-weed is 9, and when being classified as 12, rose is 4.
5. a kind of as claimed in claim 1 can the composition of auxiliary hyperglycemic, it is characterized in that, this Chinese medicine composition is powder, pill, granule, capsule, tablet as the pharmaceutical preparation of active component.
6. prepare described in claim 1 can the method for composition of auxiliary hyperglycemic, it is characterized in that, comprise the steps:
(1) take the Radix Astragali, Chinese yam, Radix Codonopsis, the root of kudzu vine, the tuber of dwarf lilyturf, the wind-weed, Radix Angelicae Sinensis, rose respectively in proportion, removing foreign material, clean, dry;
(2) by the Radix Astragali, Chinese yam, Radix Codonopsis, the root of kudzu vine, the tuber of dwarf lilyturf, the wind-weed, Radix Angelicae Sinensis, rose, put in refluxing extraction device, add 10 times of water gaging refluxing extraction 2 hours, filter to obtain supernatant, the dregs of a decoction add 8 times of water refluxing extraction 1.5 hours again, merge extracted twice liquid, be separated to obtain supernatant, supernatant concentration is become thick paste.
7. a kind of preparation according to claim 6 can the method for composition of auxiliary hyperglycemic, and it is characterized in that, described thick paste, at 70 DEG C, after dry, pulverize, is crossed 100 mesh sieves and obtained fine powder under 0.8Mpa condition.
8. according to any one of claim 1-5 a kind of can auxiliary hyperglycemic composition preparation hypoglycemic health food in application.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105521269A (en) * | 2015-12-16 | 2016-04-27 | 甘肃东方天润玫瑰科技发展有限公司 | Rose composition for treating Alzheimer disease and application of rose composition |
| CN109430854A (en) * | 2018-09-18 | 2019-03-08 | 广东精核生物科技发展有限公司 | A kind of health care product and preparation method thereof |
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| JPH08198768A (en) * | 1995-01-20 | 1996-08-06 | Osamu Mimura | Diabetes-treating agent |
| CN101590175A (en) * | 2008-05-29 | 2009-12-02 | 北京卓越同创药物研究院 | A kind of pharmaceutical preparation and preparation method thereof with hypoglycemic activity |
| CN103202470A (en) * | 2013-04-25 | 2013-07-17 | 福建永生活力生物工程有限公司 | Health food for reducing blood sugar in auxiliary manner and preparation method of health food |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH08198768A (en) * | 1995-01-20 | 1996-08-06 | Osamu Mimura | Diabetes-treating agent |
| CN101590175A (en) * | 2008-05-29 | 2009-12-02 | 北京卓越同创药物研究院 | A kind of pharmaceutical preparation and preparation method thereof with hypoglycemic activity |
| CN103202470A (en) * | 2013-04-25 | 2013-07-17 | 福建永生活力生物工程有限公司 | Health food for reducing blood sugar in auxiliary manner and preparation method of health food |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN105521269A (en) * | 2015-12-16 | 2016-04-27 | 甘肃东方天润玫瑰科技发展有限公司 | Rose composition for treating Alzheimer disease and application of rose composition |
| CN105521269B (en) * | 2015-12-16 | 2018-02-13 | 甘肃东方天润玫瑰科技发展有限公司 | A kind of rose composition for treating Alzheimer's disease and its application |
| CN109430854A (en) * | 2018-09-18 | 2019-03-08 | 广东精核生物科技发展有限公司 | A kind of health care product and preparation method thereof |
| CN109430854B (en) * | 2018-09-18 | 2021-10-26 | 广东精核生物科技发展有限公司 | Health product and preparation method thereof |
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