CN104508114A - 用于在细胞中表达基因的启动子 - Google Patents
用于在细胞中表达基因的启动子 Download PDFInfo
- Publication number
- CN104508114A CN104508114A CN201380032068.1A CN201380032068A CN104508114A CN 104508114 A CN104508114 A CN 104508114A CN 201380032068 A CN201380032068 A CN 201380032068A CN 104508114 A CN104508114 A CN 104508114A
- Authority
- CN
- China
- Prior art keywords
- seq
- promoter
- sequence
- dna
- dna sequence
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
- C12N9/18—Carboxylic ester hydrolases (3.1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2408—Glucanases acting on alpha -1,4-glucosidic bonds
- C12N9/2411—Amylases
- C12N9/2428—Glucan 1,4-alpha-glucosidase (3.2.1.3), i.e. glucoamylase
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/24—Hydrolases (3) acting on glycosyl compounds (3.2)
- C12N9/2402—Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
- C12N9/2405—Glucanases
- C12N9/2434—Glucanases acting on beta-1,4-glucosidic bonds
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Botany (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP12172605 | 2012-06-19 | ||
| EP12172605.3 | 2012-06-19 | ||
| PCT/EP2013/062490 WO2013189878A1 (en) | 2012-06-19 | 2013-06-17 | Promoters for expressing a gene in a cell |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN104508114A true CN104508114A (zh) | 2015-04-08 |
Family
ID=48703430
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201380032068.1A Pending CN104508114A (zh) | 2012-06-19 | 2013-06-17 | 用于在细胞中表达基因的启动子 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20150197760A1 (enExample) |
| EP (1) | EP2861714A1 (enExample) |
| CN (1) | CN104508114A (enExample) |
| BR (1) | BR112014031526A2 (enExample) |
| IN (1) | IN2014DN10111A (enExample) |
| WO (1) | WO2013189878A1 (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112795567A (zh) * | 2020-12-24 | 2021-05-14 | 广东省微生物研究所(广东省微生物分析检测中心) | 一种深海真菌FS140 O-甲基转移酶基因GliM启动子及其应用 |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013191651A1 (en) * | 2012-06-19 | 2013-12-27 | Nanyang Technological University | An expression construct for sensing cell density and substrate availability and its use in conversion of hydroxycinnamic acids |
| US20190330612A1 (en) | 2016-06-30 | 2019-10-31 | Danisco Us Inc | Aspartic proteases |
| US10035997B2 (en) * | 2016-07-21 | 2018-07-31 | Fornia Biosolutions, Inc. | G24 glucoamylase compositions and methods |
| US11634673B2 (en) * | 2017-09-29 | 2023-04-25 | Dupont Nutrition Biosciences Aps | Production of brewer's wort having increase fermentable sugars for fermentation |
| WO2019173424A1 (en) | 2018-03-09 | 2019-09-12 | Danisco Us Inc | Glucoamylases and methods of use thereof |
| CN110331144B (zh) * | 2019-08-01 | 2023-01-20 | 天津科技大学 | 一种真菌启动子及其应用 |
| CN113061538A (zh) * | 2021-03-23 | 2021-07-02 | 江南大学 | 一种构巢曲霉自诱导型表达系统及其应用 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011054899A1 (en) * | 2009-11-04 | 2011-05-12 | Dsm Ip Assets B.V. | Talaromyces transformants |
Family Cites Families (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5198345A (en) | 1985-04-15 | 1993-03-30 | Gist-Brocades N.V. | Vectors in use in filamentous fungi |
| DK122686D0 (da) | 1986-03-17 | 1986-03-17 | Novo Industri As | Fremstilling af proteiner |
| CA1341226C (en) | 1988-08-16 | 2001-05-01 | Wim Van Hartingsveldt | Gene replacement as a tool for the construction of aspergillus strains |
| WO1994004673A1 (en) | 1992-08-19 | 1994-03-03 | Alko Group Ltd. | Fungal promoters active in the presence of glucose |
| EP0673429B1 (en) | 1992-12-10 | 2002-06-12 | Dsm N.V. | Production of heterologous proteins in filamentous fungi |
| EP1321523A3 (en) | 1993-07-23 | 2004-03-03 | DSM IP Assets B.V. | Selection marker gene free recombinant strains; a method for obtaining them and the use of these strains |
| CN1192108C (zh) | 1994-06-03 | 2005-03-09 | 诺沃奇梅兹生物技术有限公司 | 纯化的毁丝霉属漆酶及编码该酶的核酸 |
| WO1996000787A1 (en) | 1994-06-30 | 1996-01-11 | Novo Nordisk Biotech, Inc. | Non-toxic, non-toxigenic, non-pathogenic fusarium expression system and promoters and terminators for use therein |
| US5795737A (en) | 1994-09-19 | 1998-08-18 | The General Hospital Corporation | High level expression of proteins |
| KR100576576B1 (ko) | 1997-02-20 | 2006-05-04 | 디에스엠 아이피 어셋츠 비.브이. | 화학적 합성 배지를 이용하는 가치있는 화합물들의 산업적 규모의 발효적 생산 |
| EP2298913A1 (en) | 1997-04-11 | 2011-03-23 | DSM IP Assets B.V. | Gene conversion as a tool for the construction of recombinant industrial filamentous fungi |
| ATE367439T1 (de) | 1997-12-22 | 2007-08-15 | Dsm Ip Assets Bv | Expressionsklonierung in filamentösen pilzen |
| WO2001021779A2 (en) | 1999-09-17 | 2001-03-29 | Dsm N.V. | Penicillium chrysogenum transcriptional activator blar, a pathway specific regulator of beta-lactam biosynthesis, and uses therof |
| AU2005229437A1 (en) | 2004-04-02 | 2005-10-13 | Dsm Ip Assets B.V. | Filamentous fungal mutants with improved homologous recombination efficiency |
| CN102286483B (zh) | 2004-04-16 | 2014-06-04 | 中化帝斯曼制药有限公司荷兰公司 | 用于在真菌细胞中表达基因的真菌启动子 |
| US20080227148A1 (en) | 2005-03-01 | 2008-09-18 | Thibaut Jose Wenzel | Aspergillus Promotors for Expressing a Gene in a Fungal Cell |
| JP2010517587A (ja) | 2007-02-15 | 2010-05-27 | ディーエスエム アイピー アセッツ ビー.ブイ. | 関心のある化合物を生産するための組み換え宿主細胞 |
| US20100120154A1 (en) | 2007-03-21 | 2010-05-13 | Dsm Ip Assets B.V. | Method for homologous recombination |
| BRPI0911966B1 (pt) * | 2008-05-11 | 2018-11-13 | Univ Stellenbosch | polinucleotídeo codificando uma celobioidrolase |
-
2013
- 2013-06-17 US US14/408,089 patent/US20150197760A1/en not_active Abandoned
- 2013-06-17 EP EP13732397.8A patent/EP2861714A1/en not_active Withdrawn
- 2013-06-17 CN CN201380032068.1A patent/CN104508114A/zh active Pending
- 2013-06-17 IN IN10111DEN2014 patent/IN2014DN10111A/en unknown
- 2013-06-17 BR BR112014031526A patent/BR112014031526A2/pt not_active IP Right Cessation
- 2013-06-17 WO PCT/EP2013/062490 patent/WO2013189878A1/en not_active Ceased
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2011054899A1 (en) * | 2009-11-04 | 2011-05-12 | Dsm Ip Assets B.V. | Talaromyces transformants |
Non-Patent Citations (1)
| Title |
|---|
| PATRICK MURRAYA等: "Expression in Trichoderma reesei and characterisation of a thermostable family 3 β-glucosidase from the moderately thermophilic fungus Talaromyces emersonii", 《PROTEIN EXPRESSION AND PURIFICATION》, vol. 38, no. 2, 31 December 2004 (2004-12-31), XP004649879, DOI: 10.1016/j.pep.2004.08.006 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112795567A (zh) * | 2020-12-24 | 2021-05-14 | 广东省微生物研究所(广东省微生物分析检测中心) | 一种深海真菌FS140 O-甲基转移酶基因GliM启动子及其应用 |
| CN112795567B (zh) * | 2020-12-24 | 2022-04-15 | 广东省微生物研究所(广东省微生物分析检测中心) | 一种深海真菌FS140 O-甲基转移酶基因GliM启动子及其应用 |
Also Published As
| Publication number | Publication date |
|---|---|
| IN2014DN10111A (enExample) | 2015-08-21 |
| BR112014031526A2 (pt) | 2017-08-01 |
| EP2861714A1 (en) | 2015-04-22 |
| US20150197760A1 (en) | 2015-07-16 |
| WO2013189878A1 (en) | 2013-12-27 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20150408 |