CN104502171B - A kind of automatic fluorescence sheet stainer - Google Patents

A kind of automatic fluorescence sheet stainer Download PDF

Info

Publication number
CN104502171B
CN104502171B CN201410696030.0A CN201410696030A CN104502171B CN 104502171 B CN104502171 B CN 104502171B CN 201410696030 A CN201410696030 A CN 201410696030A CN 104502171 B CN104502171 B CN 104502171B
Authority
CN
China
Prior art keywords
arms
circuit module
pin
liquid pin
operating table
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201410696030.0A
Other languages
Chinese (zh)
Other versions
CN104502171A (en
Inventor
王林
黄鹤
李慧刚
章丰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jiaxing Kaishi Biotechnology Co.,Ltd.
Original Assignee
JIAXING QUEST LIFE SCIENCE CO Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by JIAXING QUEST LIFE SCIENCE CO Ltd filed Critical JIAXING QUEST LIFE SCIENCE CO Ltd
Priority to CN201410696030.0A priority Critical patent/CN104502171B/en
Publication of CN104502171A publication Critical patent/CN104502171A/en
Application granted granted Critical
Publication of CN104502171B publication Critical patent/CN104502171B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Abstract

The present invention relates to technical field of medical inspection equipment, specifically a kind of automatic fluorescence sheet stainer.The automatic fluorescence sheet stainer includes shell, operating table surface, arm group, liquid circuit module and circuit module, the operating table surface is provided with sample rack, glass frame, reagent rack and dilution frame, the arm group includes X arms and Y arms, the Y arms are slided along X arms, Z arms are slidably connected on the Y arms, the liquid circuit module and circuit module are located at the operating table surface rear, and positioned at enclosure, the Y arms, Z arms and liquid circuit module are electrically connected with circuit module respectively, include liquid pin and waste liquid pin on the Z arms, it is described go out liquid pin and waste liquid pin it is arranged in parallel, and be slidably connected with the Z arms, it is described go out the liquid pin waste liquid pin relatively move up and down, the liquid circuit module with it is described go out liquid pin and waste liquid pin be connected.The small automatic fluorescence sheet stainer of a kind of simple structure of present invention offer, high degree of automation, cross pollution.

Description

A kind of automatic fluorescence sheet stainer
Technical field
The present invention relates to technical field of medical inspection equipment, specifically a kind of automatic fluorescence sheet stainer.
Background technology
In recent years, as autoimmune disease is given more sustained attention, autoimmunity diagnostic products and producer also constantly gush out, Spearhead unanimously points to the most abundant BLOT class products of profit margin, but most hospital clients are in operation, also locate In a low-down state of automatization level, detection project is numerous and diverse, and the announcement time cycle of transmitting messages is long, detection project hand-manipulated New detection project is increased in the excessive negative conflict for causing client;Due to specimen amount and instrument cost, the dispensing of instrument Working, it is fully under way to be able to again, and these imbalances between supply and demand limit the development in market.
The autoimmunity of current main flow is diagnosed by IIF (IFA), Western blot(BLOT)And enzyme exempts from method (EIA) three bulks composition.The automaticity of blotting is of a relatively high, due to Cost of Medical Treatment limitation, indirect immunofluorescence diagnosis Reagent producer is less, and automatization level is relatively low, but does not automate platform.IIF is autoimmunity detection Internationally recognized goldstandard in diagnostic method, and BLOT methods and enzyme are exempted from method and are had by new methodology instead risk.
, it is necessary to first sample is attached on slide before Immunofluorescence test is carried out, then it is badly in need of a sheet stainer of exploitation.
The content of the invention
The small automatic fluorescence sheet stainer of a kind of simple structure of present invention offer, high degree of automation, cross pollution.
The present invention is achieved through the following technical solutions:
A kind of automatic fluorescence sheet stainer, including shell, operating table surface, arm group, liquid circuit module and circuit module, the operation Table top is provided with sample rack, glass frame, reagent rack and dilution frame, and the arm group includes X arms and Y arms, and the Y arms are slided along X arms, Z arms are slidably connected on the Y arms, the liquid circuit module and circuit module are located at the operating table surface rear, and positioned at shell Inside, the Y arms, Z arms and liquid circuit module are electrically connected with circuit module respectively, include liquid pin and waste liquid pin, institute on the Z arms State out liquid pin and waste liquid pin be arranged in parallel, and be slidably connected with the Z arms, it is described go out the relatively described waste liquid pin of liquid pin it is upper and lower Motion, the liquid circuit module with it is described go out liquid pin and waste liquid pin be connected.
The Z arms also include Z arms base plate, the first motor, crosspointer support plate and direct current generator, and the Z arms base plate is perpendicular Nogata is provided with Z-direction line slideway upwards, and on the one hand the crosspointer support plate is slidably connected with the Z-direction line slideway, another Aspect is connected by the first Timing Belt with first motor, and the waste liquid pin is fixed on the crosspointer component by fixed block On base plate, it is described go out liquid pin be slidably connected with the fixed block by tooth bar, the direct current generator be located at the crosspointer component bottom On plate, the output end of the direct current generator is provided with gear, and the gear is meshed with the tooth bar, first motor and direct current Motor is electrically connected with the circuit module respectively.
It is described go out liquid pin and waste liquid pin on be arranged with fairlead, the fairlead is fixedly connected with the waste liquid pin, described Go out liquid pin through fairlead, and slided up and down in fairlead.
The Y arms are provided with Y-direction line slideway, X to sliding block and the second motor, and the Z arms are provided with Y-direction sliding block, the Z Arm is slidably connected by Y-direction sliding block with the Y-direction line slideway, and the Y-direction sliding block is by the second Timing Belt and the described second electricity Machine is connected, and the X is slidably connected to sliding block with the X arms, and second motor is electrically connected with the circuit module.
The operating table surface is provided with least one stop bit bar, the sample rack, glass frame, reagent rack and dilution frame frame in On the stop bit bar.
The upper surface of the glass frame is provided with some slide mounting planes, and the slide mounting plane top is provided with glass Piece, the slide mounting plane both sides are provided with a groove, and the outside of the groove is located at the slide mounting plane It is respectively arranged at the two ends with a fluting;The operating table surface is provided with two the first stop bit bars being parallel to each other, the first stop bit bar Some screens are provided with, the lower surface of the glass frame is provided with support block, and the support block is snapped in the screens.
The sample rack includes base plate, first panel and second panel, the four of the base plate, first panel and second panel Individual angle is connected by four support columns, and the support column sequentially passes through first panel, second panel and base plate from top to down, under End is fixed by nut, is arranged with Upper shaft sleeve and Lower shaft sleeve on every support column, the Upper shaft sleeve be located at the first panel and Between second panel, the Lower shaft sleeve is located between the second panel and base plate, the first panel, second panel and base plate In the vertical direction is coaxially provided with first through hole, the second through hole and third through-hole, and the diameter of the third through-hole leads to less than first Hole and the second through hole;The operating table surface is provided with two the second stop bit bars being parallel to each other, every two ends of the second stop bit bar A mounting hole is respectively provided with, the lower end of the support column is snapped in the mounting hole.
The operating table surface is provided with two group of first stop bit bar, and every group of first stop bit bar includes two first stop bit bars, one The first stop bit bar of group is used to place glass frame, and another group of the first stop bit bar is used to place reagent rack and dilution frame, the dilution frame Frame and deep-well plates dilution frame are diluted including microwell plate.
The operating table surface is provided with washes pin pond, the liquid circuit module include fluid filling pump and drawing liquid pump, the fluid filling pump and Drawing liquid pump respectively with wash pin pond and be connected, the fluid filling pump with it is described go out liquid pin be connected, the drawing liquid pump and the waste liquid pin It is connected, the fluid filling pump and drawing liquid pump are electrically connected with circuit module respectively.
The shell is renovated including one, and described renovating is connected with shell rotation, described to renovate positioned at the upper of operating table surface Side and front, and described renovate transparent shape.
The beneficial effect brought of the present invention is:
In the present invention, the automatic fluorescence sheet stainer includes shell, operating table surface, arm group, liquid circuit module and circuit module, The operating table surface is provided with sample rack, glass frame, reagent rack and dilution frame, and the arm group includes X arms, Y arms and Z arms, wherein Z It is provided with out liquid pin and waste liquid pin on arm, and then realizes out liquid pin and waste liquid pin in X to the movement in, Y-direction and Z-direction, completes Sample Dilution, it is loaded, washes pin, cleaning slide, the operating procedure such as reagent adding, the circuit module plays synthetically control action, The liquid circuit module is mainly the discharge of control cleaning fluid and waste liquid;The double needle configuration of liquid pin and waste liquid pin is set out on Z arms, On the one hand slide can be cleaned multiple times, another aspect double needle configuration can reduce cross pollution, it is described go out liquid pin be used for Sample-adding, reagent adding and output cleaning fluid, the waste liquid pin are used to for the cleaning fluid on slide to detach slide, and crosspointer respective Use during there is difference in height.
Brief description of the drawings
The present invention is described in further detail below in conjunction with accompanying drawing.
Fig. 1 is the structural representation of automatic fluorescence sheet stainer closed mode of the present invention.
Fig. 2 is the structural representation of automatic fluorescence sheet stainer open mode of the present invention.
Fig. 3 is the assembling figure of Y arms of the present invention and Z arms.
Fig. 4 is the structural representation of Z arms of the present invention.
Fig. 5 is the explosive view of operating table surface of the present invention and sample rack, glass frame, reagent rack and dilution frame.
Fig. 6 is the assembling figure of glass frame of the present invention and slide.
Fig. 7 is the structural representation of glass frame of the present invention.
Fig. 8 is the profile of sample rack of the present invention.
Fig. 9 is the structural representation of sample rack reverse side of the present invention.
Figure 10 is the structural representation of reagent rack of the present invention.
Figure 11 is the structural representation that deep-well plates of the present invention dilute frame.
Figure 12 is the structural representation that microwell plate of the present invention dilutes frame.
The corresponding label of component names is as follows in figure:
1st, shell;2nd, operating table surface;3rd, sample rack;4th, glass frame;5th, reagent rack;6th, frame is diluted;7th, X arms;8th, Y arms;9、Z Arm;10th, liquid pin is gone out;11st, waste liquid pin;12nd, Z arms base plate;13rd, the first motor;14th, crosspointer support plate;15th, direct current generator;16、 Z-direction line slideway;17th, the first Timing Belt;18th, fixed block;19th, tooth bar;20th, gear;21st, fairlead;22nd, Y-direction line slideway; 23rd, X is to sliding block;24th, the second motor;25th, Y-direction sliding block;26th, the second Timing Belt;27th, slide mounting plane;28th, slide;29th, it is recessed Groove;30th, slot;31st, the first stop bit bar;32nd, screens;33rd, support block;34th, base plate;35th, first panel;36th, second panel; 37th, support column;38th, nut;39th, Upper shaft sleeve;40th, Lower shaft sleeve;41st, first through hole;42nd, the second through hole;43rd, third through-hole;44、 Second stop bit bar;45th, mounting hole;46th, pin pond is washed;47th, fluid filling pump;48th, drawing liquid pump;49th, renovate;50th, convex tendon;51st, microwell plate Dilution frame;52nd, deep-well plates dilution frame.
Specific embodiment
Below in conjunction with the accompanying drawings and embodiment the present invention is described in further detail:
As the embodiment of automatic fluorescence sheet stainer of the present invention, as shown in Figure 1, Figure 2, Fig. 3, Fig. 4, Fig. 5, Fig. 6, Fig. 7, figure 8th, shown in Fig. 9, Figure 10, Figure 11 and Figure 12, including shell 1, operating table surface 2, arm group, liquid circuit module and circuit module, the behaviour Make table top and be provided with sample rack 3, glass frame 4, reagent rack 5 and dilution frame 6, the arm group includes X arms 7 and Y arms 8, the Y arms 8 Slided along X arms 7, Z arms 9 are slidably connected on the Y arms 8, after the liquid circuit module and circuit module are located at the operating table surface 2 Side, and inside shell 1, the Y arms 8, Z arms 9 and liquid circuit module are electrically connected with circuit module respectively, are included on the Z arms 9 Go out liquid pin 10 and waste liquid pin 11, it is described go out liquid pin 10 and waste liquid pin 11 it is arranged in parallel, and be slidably connected with the Z arms 9, institute The relatively described waste liquid pin 11 of liquid pin 10 is stated out to move up and down, the liquid circuit module with it is described go out liquid pin 10 and waste liquid pin 11 be connected It is logical.The double needle configuration of liquid pin 10 and waste liquid pin 11 is set out on Z arms 9, on the one hand slide 27 can be cleaned multiple times, separately One side double needle configuration can reduce cross pollution, it is described go out liquid pin 10 be used to being loaded, reagent adding and output cleaning fluid, it is described useless Liquid pin 11 is used to for the cleaning fluid on slide to detach slide, and crosspointer has difference in height during respective use; In addition, it is described go out liquid needle set have detection liquid level function.
In the present embodiment, the Z arms 9 also include Z arms base plate 12, the first motor 13, crosspointer support plate 14 and direct current Machine 15, the in the vertical direction of Z arms base plate 12 is provided with Z-direction line slideway 16, the one side of crosspointer support plate 14 and institute State Z-direction line slideway 16 to be slidably connected, be on the other hand connected with first motor 13 by the first Timing Belt 17, it is described useless Liquid pin 11 is fixed on the crosspointer support plate 14 by fixed block 18, it is described go out liquid pin 10 pass through tooth bar 19 and the fixation Block 18 is slidably connected, and on the crosspointer support plate 14, the output end of the direct current generator 15 sets the direct current generator 15 Have gear 20, the gear 20 is meshed with the tooth bar 19, first motor 13 and direct current generator 15 respectively with the electricity Road module electrical connection.The crosspointer support plate 14 drives out liquid pin 10 and waste liquid pin 11 simultaneously under the driving of the first motor 13 Move up and down, when needing sample-adding, reagent adding or adding cleaning fluid, the direct current generator 15 is rotated, by gear 20 and tooth bar 19 intermeshing, make it is described go out liquid pin 10 moved downward relative to the waste liquid pin 11, and then realize sample-adding, reagent adding and add Cleaning fluid etc. operate, now, it is described go out liquid pin 10 lower end less than the waste liquid pin 11 lower end, both have a height Difference, then effectively reduce cross pollution, when when slide is cleaned, it is described go out liquid pin 10 it is relative under the drive of direct current generator 15 Waste liquid pin 11 upwards move, now, it is described go out liquid pin 10 lower end higher than the waste liquid pin 11 lower end, between the two with one Individual difference in height, effectively reduces cross pollution.
In the present embodiment, it is described go out liquid pin 10 and waste liquid pin 11 on be arranged with fairlead 21, the fairlead 21 with it is described Waste liquid pin 11 is fixedly connected, it is described go out liquid pin 10 pass through fairlead 21, and slide up and down in the fairlead 21.The fairlead 21 The depth of parallelism between liquid pin 10 and waste liquid pin 11 can well be ensured, prevent out liquid pin 10 to go out during up and down motion The problem of existing position skew, is fixed with two fairleads 21 on the waste liquid pin 11, it is described go out liquid pin 10 can be in two guiding Slided up and down in set 21.
In the present embodiment, the Y arms 8 are provided with Y-direction line slideway 22, X to the motor 24 of sliding block 23 and second, the Z arms 9 Y-direction sliding block 25 is provided with, the Z arms 9 are slidably connected by Y-direction sliding block 25 with the Y-direction line slideway 22, the Y-direction sliding block 25 are connected by the second Timing Belt 26 with second motor 24, and the X is slidably connected to sliding block 23 with the X arms 7, described Second motor 24 is electrically connected with the circuit module.Under the drive of the second motor 24, the Z arms 9 can be moved along Y arms 8, Y arms 8 In the 3rd motor(It is to show in figure)Drive under can be moved along X arms 7, and then realize Z arms 9 in any one position of horizontal plane The place of putting can stop, and complete dilution, sample-adding, reagent adding, add the operation such as cleaning fluid.
In the present embodiment, the upper surface of the glass frame 4 is provided with five slide mounting planes 27, and the slide is installed flat The top of face 27 is provided with slide 28, and the both sides of slide mounting plane 27 are provided with a groove 29, the outside of the groove 29 A fluting 30 is respectively arranged at the two ends with positioned at the slide mounting plane 27;The operating table surface 2 is provided with two and is parallel to each other The first stop bit bar 31, the first stop bit bar 31 is provided with three screens 32, and the lower surface of the glass frame 4 is provided with support Block 33, the support block 33 is snapped in the screens 32.A convex tendon 50, institute are provided between two neighboring slide mounting plane 27 Slide 28 is stated to be installed on slide mounting plane 27, and between adjacent two convex tendons 50, when user needs to take slide 28 When lower, the two ends of slide 28 only need to be respectively pressed against by forefinger and thumb, and be located at 27 liang of slide mounting plane respectively Easily slide 28 can be removed in the fluting 30 at end, the effect of the fluting 30 is stepped down to forefinger and thumb;It is described recessed The effect of groove 29 one side, can be as spillage accumulator tank when cleaning fluid overflows slide 28, and it is appropriate on the other hand can to add Water, as the evaporation of moisture carries out moisturizing to slide 28;Three screens 32 simultaneously on the first stop bit bar 31, then can be simultaneously Three glass frames 4 are placed, and then dye piece can be carried out simultaneously with multiple slides 28, improve the efficiency of dye piece, the support block 33 Just snap in the screens 32, can be very good to realize in the horizontal direction spacing, prevent the movement of glass frame 4, and user Operation is more convenient.
In the present embodiment, the sample rack 3 includes base plate 34, first panel 35 and second panel 36, the base plate 34, the One panel 35 is connected with four angles of second panel 36 by four support columns 37, and the support column 37 is worn successively from top to down First panel 35, second panel 36 and base plate 34 are crossed, lower end is fixed by nut 38, and Upper shaft sleeve is arranged with every support column 37 39 and Lower shaft sleeve 40, the Upper shaft sleeve 39 is located between the first panel 35 and second panel 36, and the Lower shaft sleeve 40 is located at Between the second panel 36 and base plate 34, the first panel 35, second panel 36 and the in the vertical direction of base plate 34 are coaxial It is provided with first through hole 41, the second through hole 42 and third through-hole 43, the diameter of the third through-hole 43 is less than first through hole 41 and the Two through holes 42;The operating table surface 2 is provided with two the second stop bit bars 44 being parallel to each other, every two ends of the second stop bit bar 44 A mounting hole 45 is respectively provided with, the lower end of the support column 37 is snapped in the mounting hole 45.The frame of the sample rack 3 stops in second On the bar 44 of position, and there is position-limiting action in the horizontal direction, prevent the sample rack 3 during piece is contaminated from the feelings of displacement occur Condition.
In the present embodiment, the operating table surface 2 is provided with two group of first stop bit bar 31, and every group of first stop bit bar 31 includes two The first stop bit of root bar 31, one group of first stop bit bar 31 is used to place glass frame 4, and another group of the first stop bit bar is used to place reagent rack 5 include that microwell plate dilutes frame 51 and deep-well plates dilute frame 52 with dilution frame 6, the dilution frame 6.Two group of first knot of stop bit bar 31 Structure is identical, the card on the glass frame 4, reagent rack 5, microwell plate dilution frame 51 and the deep-well plates dilution stop bit bar 31 of frame 52 and first The physical dimension that position 32 is mutually clamped is also identical, therefore, the glass frame 4, reagent rack 5, microwell plate dilution frame 51 and deep-well plates Dilution frame 52 can be arbitrarily placed in any one screens 32 on two group of first stop bit bar 31, so make operating table surface can Denaturation is further improved.
In the present embodiment, the operating table surface 2 is provided with washes pin pond 46, and the liquid circuit module includes fluid filling pump 47 and drawing liquid Pump 48, the fluid filling pump 47 and drawing liquid pump 48 respectively with wash pin pond 46 and be connected, the fluid filling pump 47 with it is described go out the phase of liquid pin 10 Connection, the drawing liquid pump 48 is connected with the waste liquid pin 11, and the fluid filling pump 47 and drawing liquid pump 48 are electric with circuit module respectively Connection.Cross pollution is further reduced for washing out liquid pin 10 and waste liquid pin 11 in the pin pond 46 of washing.
In the present embodiment, the shell 1 renovates 49 including one, it is described renovate 49 and rotated with shell 1 be connected, it is described to renovate 49 are located at the tops and front of operating table surface 2, and described renovate 49 transparent shapes.User is being needed in operating table surface 2 Sample rack 3, reagent rack 5, glass frame 4 and dilution frame 6 be when being operated, need to only open it is described renovate 49, carrying out dye piece During operation, 49 are renovated in closure state, and then ensure the effect of dye piece.
Certainly, one or three fairleads are fixed with the waste liquid pin;Have four on the upper surface of the glass frame Individual or six or eight slide mounting planes, card has a slide on each slide mounting plane.So, also all in this hair Within bright protection domain, no longer repeat one by one here.

Claims (9)

1. a kind of automatic fluorescence sheet stainer, it is characterised in that including shell, operating table surface, arm group, liquid circuit module and circuit module, The operating table surface is provided with sample rack, glass frame, reagent rack and dilution frame, and the arm group includes X arms and Y arms, the Y arms edge X arms are slided, and Z arms are slidably connected on the Y arms, and the liquid circuit module and circuit module are located at the operating table surface rear, and Positioned at enclosure, the Y arms, Z arms and liquid circuit module are electrically connected with circuit module respectively, include on the Z arms liquid pin and Waste liquid pin, it is described go out liquid pin and waste liquid pin it is arranged in parallel, and be slidably connected with the Z arms, it is described go out liquid pin it is relatively described Waste liquid pin moves up and down, the liquid circuit module with it is described go out liquid pin and waste liquid pin be connected;The Z arms also include Z arms base plate, the One motor, crosspointer support plate and direct current generator, the Z arms base plate in the vertical direction are provided with Z-direction line slideway, the crosspointer On the one hand support plate is slidably connected with the Z-direction line slideway, on the other hand by the first Timing Belt and first motor Be connected, the waste liquid pin is fixed on the crosspointer support plate by fixed block, it is described go out liquid pin by tooth bar with it is described Fixed block is slidably connected, and on the crosspointer support plate, the output end of the direct current generator is provided with tooth to the direct current generator Wheel, the gear is meshed with the tooth bar, and first motor and direct current generator are electrically connected with the circuit module respectively.
2. fluorescence sheet stainer as claimed in claim 1 automatic, it is characterised in that it is described go out liquid pin and waste liquid pin on be arranged with and lead To set, the fairlead is fixedly connected with the waste liquid pin, it is described go out liquid pin pass through fairlead, and in the fairlead on glide It is dynamic.
3. fluorescence sheet stainer as claimed in claim 2 automatic, it is characterised in that the Y arms be provided with Y-direction line slideway, X to Sliding block and the second motor, the Z arms are provided with Y-direction sliding block, and the Z arms are slided with the Y-direction line slideway by Y-direction sliding block and connected Connect, the Y-direction sliding block is connected by the second Timing Belt with second motor, the X is slided with the X arms to sliding block and connected Connect, second motor is electrically connected with the circuit module.
4. the automatic fluorescence sheet stainer as described in claim any one of 1-3, it is characterised in that the operating table surface be provided with to A kind of few stop bit bar, the sample rack, glass frame, reagent rack and dilution frame frame are on the stop bit bar.
5. fluorescence sheet stainer as claimed in claim 4 automatic, it is characterised in that the upper surface of the glass frame is provided with five Slide mounting plane, slide mounting plane top is provided with slide, the slide mounting plane both sides be provided with one it is recessed Groove, the outside of the groove is respectively arranged at the two ends with a fluting positioned at the slide mounting plane;The operating table surface is provided with Two the first stop bit bars being parallel to each other, the first stop bit bar is provided with three screens, is set on the lower surface of the glass frame There is support block, the support block is snapped in the screens.
6. fluorescence sheet stainer as claimed in claim 4 automatic, it is characterised in that the sample rack include base plate, first panel and Four angles of second panel, the base plate, first panel and second panel are connected by four support columns, the support column from First panel, second panel and base plate are sequentially passed through under above, lower end is fixed by nut, and axle is arranged with every support column Set and Lower shaft sleeve, the Upper shaft sleeve are located between the first panel and second panel, and the Lower shaft sleeve is located at second face Between plate and base plate, the first panel, second panel and base plate in the vertical direction are coaxially provided with first through hole, the second through hole And third through-hole, the diameter of the third through-hole is less than first through hole and the second through hole;The operating table surface is provided with two phases Mutual parallel the second stop bit bar, every second stop bit bar is respectively arranged at the two ends with a mounting hole, and the lower end of the support column snaps in In the mounting hole.
7. fluorescence sheet stainer as claimed in claim 4 automatic, it is characterised in that the operating table surface is provided with two group first and stops Position bar, every group of first stop bit bar includes two first stop bit bars, and one group of first stop bit bar is used to place glass frame, another group first Stop bit bar is used to place reagent rack and dilution frame, and the dilution frame includes that microwell plate dilutes frame and deep-well plates dilution frame.
8. the automatic fluorescence sheet stainer as described in claim any one of 5-7, it is characterised in that the operating table surface is provided with washes Pin pond, the liquid circuit module includes fluid filling pump and drawing liquid pump, the fluid filling pump and drawing liquid pump respectively with wash pin pond and be connected, it is described Fluid filling pump with it is described go out liquid pin be connected, the drawing liquid pump is connected with the waste liquid pin, and the fluid filling pump and drawing liquid pump are distinguished Electrically connected with circuit module.
9. fluorescence sheet stainer as claimed in claim 1 automatic, it is characterised in that the shell is renovated including, described to renovate Rotated with shell and be connected, it is described to renovate positioned at the top and front of operating table surface, and described renovate transparent shape.
CN201410696030.0A 2014-11-27 2014-11-27 A kind of automatic fluorescence sheet stainer Active CN104502171B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201410696030.0A CN104502171B (en) 2014-11-27 2014-11-27 A kind of automatic fluorescence sheet stainer

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201410696030.0A CN104502171B (en) 2014-11-27 2014-11-27 A kind of automatic fluorescence sheet stainer

Publications (2)

Publication Number Publication Date
CN104502171A CN104502171A (en) 2015-04-08
CN104502171B true CN104502171B (en) 2017-05-31

Family

ID=52943590

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201410696030.0A Active CN104502171B (en) 2014-11-27 2014-11-27 A kind of automatic fluorescence sheet stainer

Country Status (1)

Country Link
CN (1) CN104502171B (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105547794B (en) * 2016-02-18 2018-12-04 南昌德漫多科技有限公司 A kind of immunostaining machine
CN108106911A (en) * 2017-12-29 2018-06-01 山东仕达思生物产业有限公司 A kind of full-automatic glass slide smear dyeing machine
CN108117972A (en) * 2017-12-30 2018-06-05 郑州游爱网络技术有限公司 A kind of plasma pigment inhibits reaction unit
CN108593400A (en) * 2018-04-26 2018-09-28 福州迈新生物技术开发有限公司 The dyeing mechanism for biological sample on glass slide with loading system
EP3841370A4 (en) * 2018-12-20 2021-12-15 Leica Biosystems Melbourne Pty Ltd A slide output module
US20220032309A1 (en) * 2018-12-20 2022-02-03 Leica Biosystems Melbourne Pty Ltd A slide tray assembly

Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5439649A (en) * 1993-09-29 1995-08-08 Biogenex Laboratories Automated staining apparatus
US6495106B1 (en) * 1998-03-24 2002-12-17 Biogenex Laboratories Automated staining apparatus
CN1789957A (en) * 2005-12-10 2006-06-21 王海波 Automatic sputum smear staining instrument for medical use and staining method thereof
CN1965223A (en) * 2004-03-02 2007-05-16 丹麦达科有限公司 Reagent delivery system, dispensing device and container for a biological staining apparatus
CN101021455A (en) * 2007-03-22 2007-08-22 广州安必平医药科技有限公司 Slide-making staining machine and method for slide-making staining method
CN103175724A (en) * 2013-03-20 2013-06-26 嘉兴凯实生物科技有限公司 Full-automatic dyeing machine
CN203083865U (en) * 2013-03-20 2013-07-24 嘉兴凯实生物科技有限公司 Full-automatic dyeing machine
CN103217327A (en) * 2013-03-28 2013-07-24 广州安必平医药科技有限公司 Tissue slice and cell smear sample treating device
CN204330454U (en) * 2014-11-27 2015-05-13 嘉兴凯实生物科技有限公司 A kind of fluorescence sheet stainer automatically

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7648678B2 (en) * 2002-12-20 2010-01-19 Dako Denmark A/S Method and system for pretreatment of tissue slides

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5439649A (en) * 1993-09-29 1995-08-08 Biogenex Laboratories Automated staining apparatus
US6495106B1 (en) * 1998-03-24 2002-12-17 Biogenex Laboratories Automated staining apparatus
CN1965223A (en) * 2004-03-02 2007-05-16 丹麦达科有限公司 Reagent delivery system, dispensing device and container for a biological staining apparatus
CN1789957A (en) * 2005-12-10 2006-06-21 王海波 Automatic sputum smear staining instrument for medical use and staining method thereof
CN101021455A (en) * 2007-03-22 2007-08-22 广州安必平医药科技有限公司 Slide-making staining machine and method for slide-making staining method
CN103175724A (en) * 2013-03-20 2013-06-26 嘉兴凯实生物科技有限公司 Full-automatic dyeing machine
CN203083865U (en) * 2013-03-20 2013-07-24 嘉兴凯实生物科技有限公司 Full-automatic dyeing machine
CN103217327A (en) * 2013-03-28 2013-07-24 广州安必平医药科技有限公司 Tissue slice and cell smear sample treating device
CN204330454U (en) * 2014-11-27 2015-05-13 嘉兴凯实生物科技有限公司 A kind of fluorescence sheet stainer automatically

Also Published As

Publication number Publication date
CN104502171A (en) 2015-04-08

Similar Documents

Publication Publication Date Title
CN104502171B (en) A kind of automatic fluorescence sheet stainer
CN204330454U (en) A kind of fluorescence sheet stainer automatically
CN209727592U (en) A kind of agitating device of tomato jam detection
CN204072013U (en) Brush chospticks machine
CN205732179U (en) A kind of barrelled water bucket cleaning inside device
CN104415942A (en) Keyboard dust remover
CN203870115U (en) Mechanical blood card sampling arm
CN204330452U (en) A kind of fluorescence sheet stainer operating table surface automatically
CN204177561U (en) A kind of endurance test equipment of glass-frame riser
CN203356135U (en) PCB cleaning device
CN215702190U (en) Automatic blanking device of circuit board
CN207231080U (en) A kind of chemical engineering experiment test tube dehydrating unit
CN103405220B (en) Water turning wheel type fatigue tester
CN204695587U (en) English reading assistor
CN115318689A (en) Dustproof device and dustproof method for computer
CN207463267U (en) One kind is convenient for clean chemistry experiment operation console
CN209439159U (en) A kind of drum cleaning device
CN207681103U (en) A kind of ultrasonic cleaning equipment for liquid crystal display production
CN201444376U (en) Automatic electric-hydraulic analogue underground water simulation system
CN209901900U (en) Computer screen cleaning device
CN205995876U (en) A kind of cleaning equipment being applied to immunoassay instrument
CN207285127U (en) A kind of environmental protection fruit washing apparatus
CN205008343U (en) Wash tank ware cardump device
CN204770814U (en) Drilling work platform
CN203841681U (en) Water rotating wheel type fatigue tester

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
PE01 Entry into force of the registration of the contract for pledge of patent right

Denomination of invention: Automatic fluorescence slice dyeing machine

Effective date of registration: 20200710

Granted publication date: 20170531

Pledgee: Agricultural Bank of China Limited by Share Ltd. Jiaxing science and Technology Branch

Pledgor: JIAXING QUEST BIOTECHNOLOGY Co.,Ltd.

Registration number: Y2020330000469

PE01 Entry into force of the registration of the contract for pledge of patent right
CP03 Change of name, title or address

Address after: 314000 floor 3, building 1, floor 2-3, building 2, No. 3535, linggongtang Road, Nanhu District, Jiaxing City, Zhejiang Province

Patentee after: Jiaxing Kaishi Biotechnology Co.,Ltd.

Address before: 314000 3, east 6, 6 linggong Road, South Lake District, Jiaxing, Zhejiang (Jiaxing science and technology city)

Patentee before: JIAXING QUEST BIOTECHNOLOGY Co.,Ltd.

CP03 Change of name, title or address
PC01 Cancellation of the registration of the contract for pledge of patent right

Date of cancellation: 20211126

Granted publication date: 20170531

Pledgee: Agricultural Bank of China Limited by Share Ltd. Jiaxing science and Technology Branch

Pledgor: JIAXING QUEST BIOTECHNOLOGY Co.,Ltd.

Registration number: Y2020330000469

PC01 Cancellation of the registration of the contract for pledge of patent right