CN104491215A - 一种治疗痿症的中药 - Google Patents
一种治疗痿症的中药 Download PDFInfo
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Abstract
本发明涉及一种治疗痿症的中药，由以下重量配比的药材制备而成：八月札2份、楮实6份、大血藤3份、柳叶2份、漏芦2份、肿节风9份、刺蒺藜6份、白毛夏枯草7份、墨旱莲2份、白蔹5份、秦皮3份、勾儿茶2份、牛肝3份。临床实验证明，本发明能够安全有效治疗痿症。
Description
技术领域
本发明涉及一种中药，尤其是涉及一种治疗痿症的中药。
背景技术
中医称痿病系指外感或内伤，使精血受损，肌肉筋脉失养以致肢体弛缓、软弱无力，甚至日久不用，引起肌肉萎缩或瘫痪的一种病证。痿者萎也，枯萎之义，即指肢体痿弱，肌肉萎缩。凡手足或其他部位的肌肉痿弱无力，弛缓不收者均属痿病范畴。因多发生在下肢，故又有“痿蹙”之称。
对于痿症其在临床表现上常见于以筋脉弛缓，肢体肌肉软弱无力，不能随意活动，甚至肌肉萎缩或瘫痪为主要证候特征。但因证不同，临床表现各异。有急性起病，进行性加重者；有缓慢发病者；也有时轻时重，周期性发作者；有疲劳后发病者，有睡卧后发作者。有以女性多见，有以男性为主者。一般以下肢发病多见，也有见于上肢、肩背者，有影响窍隧，难于张口、睁目者，甚至瘫痪于床者。有以肢体近端肌肉弱于远端者，或以肢体远端肌肉弱于近端者。初则仅为肌肉软弱无力，久则肌肉萎缩不用。
目前对于痿症目前尚缺少公认安全有效的治疗药物，且现有的药物效果不都理想，并有副作用。因此研究开发一种安全有效的治疗痿症的中药非常有实用价值。
本发明中药所涉及药材的研究现状如下：
八月札
【来源】 为本通科植物木通、三叶木通、白本通的果实。
【功能主治】 舒肝理气，活血止痛，除烦利尿。
【用法用量】 内服：煎汤，0。5～1两；或浸酒。
楮实
【来源】 为桑科植物构树的果实。
【功能主治】 滋肾；清肝明目；健脾利水。
【用法用量】 内服：煎汤，6-10g
大血藤
【来源】 为木通科植物大血藤的茎。
【功能主治】 清热解毒，活血，祛风。用于肠痈腹痛，经闭痛经，风湿痹痛，跌扑肿痛。
【用法用量】 内服：煎汤，3～5钱
柳叶
【来源】 为杨柳科植物垂柳的叶。
【功能主治】 清热；解毒；利尿；平肝；止痛。
【用法用量】 内服:煎汤，鲜者1～2两。
漏芦
【来源】 药材基源：为菊科植物祁州漏芦或禹州漏芦的根。
【功能主治】 清热解毒；活血通乳。主疮疖肿毒
【用法用量】 内服：煎汤，9-15g。
肿节风
【来源】 本品为金粟兰科植物草珊瑚Sarcandra glabra （Thunb.）Nakai的干燥全株。
【功能主治】 清热凉血，活血消斑，祛风通络。
【用法用量】 9～30g。
刺蒺藜
【来源】 药材基源：为蒺藜科植物蒺藜和大花疾藜的果实。
【功能主治】 平肝；解郁；祛风明目。
【用法用量】 内服：煎汤，6-9g
白毛夏枯草
【来源】 为唇形科植物筋骨草的全株。
【功能主治】 止咳化痰，清热，凉血，消肿，解毒,治危笃肺痈痿症.
【用法用量】 内服：煎汤，10-30g
墨旱莲
【来源】 为菊科植物鳢肠的全草。
【功能主治】 凉血，止血，补肾，益阴。
【用法用量】 内服：煎汤，0.3～1两
白蔹
【来源】 为葡萄科植物白蔹的根。
【功能主治】 清热解毒，消痈散结。
【用法用量】 4.5～9g
秦皮
【来源】 为木犀科植物苦枥白蜡树，小叶白蜡树或秦岭白蜡树的树皮。
【功能主治】 清热燥湿，平喘止咳，明目。
【用法用量】 内服：煎汤，1.5～3钱
勾儿茶
【来源】 为鼠李科植物牛鼻拳的根。
【功能主治】 补脾利湿，舒筋活络，调经止痛。
【用法用量】 根1～2两
牛肝
【来源】 牛科动物黄牛或水牛的肝。
【功能主治】 补肝；养血。主虚劳赢瘦；血虚萎黄；惊痫。
【用法用量】 内服：煮食或入丸、散。
发明内容
本发明旨在提供一种治疗痿症的中药，通过选择合适的药材及其配比，达到安全有效治愈痿症的目的。
为了达到上述目的，本发明采用以下技术方案：
一种治疗痿症的中药，其特征在于，由以下重量配比的药材制备而成：八月札2份、楮实6份、大血藤3份、柳叶2份、漏芦2份、肿节风9份、刺蒺藜6份、白毛夏枯草7份、墨旱莲2份、白蔹5份、秦皮3份、勾儿茶2份、牛肝3份。
下面结合临床实验数据说明本发明的有益效果：
1、一般资料
发明人2010年3月-2014年8月间共收集85例痿症的门诊患者，年龄23-55岁，病程1-12月。随机分为：治疗组60例，空白组25例。两组年龄、病情等资料无显著性差异，具有可比性。
2、试验方法
2.1治疗方法
对照组口服舒筋活血片，按照说明书服用。疗程2个月。
治疗组口服本发明按照具体实施例1制得的胶囊，每日2次，疗程2个月。
2.2观察项目：实验前后，对疼痛，麻痹，萎缩等情况进行观察，记录。
3、疗效标准与治疗结果
3.1疗效标准
痊愈：临床症状如肌肉无力等症状全部消失，试验室检查正常，愈后半年内未见复发。
好转：临床症状减轻，实验室检查改善或正常。
无效：临床症状、实验室检查无明显好转或加重。
表1 两组疗效比较
| 组别 | n | 痊愈 | 好转 | 无效 | 总有效率（%） | 不良反应例 |
| 治疗组 | 60 | 25(41.6%) | 28(46.6%) | 7(11.7%) | 88.3% | 0 |
| 空白组 | 25 | 0(0%) | 4(16.0%) | 21(84.0%) | 16.0% | 0 |
为证明本发明具有很好的疗效，列举典型病例如下：
1、陈某，男，26岁，IT白领，本人主诉近段时间感觉肢体肌肉软弱无力，严重时不能随意活动，特别是上肢手臂有时不能扶握杯子，日常生活受其影响，但手部无疼痛症状随后赴当地医院就诊，确诊为痿症，后医院采用西医常规药物治疗一周后效果不佳，并伴有症状加重趋势。后给予本发明中药治疗，服用一周后，痿症症状有所好转，肢体力气缓慢恢复，续用一个半月后，病情明显好转，至今并无复发。
2、齐某，女，42岁，2013年10月18日初诊。其主诉：下肢体软弱无力，严重时双脚无力导致无法正常站立但双脚却无明显疼痛感，由此已严重影响生活、工作等。随后及时赴当地医院诊断，通过肌力，肌萎缩，肌电图、肌活检与酶学等等检查后确诊为痿症，医院立即采用西医治疗，经5天治疗不见症状有所好转。后给予本发明中药治疗，服用一周后，双脚力气恢复能够逐步站立，，继续服用一个月后，病情康复完全，并且至今无复发。
3、孙某某，男，38岁，务农。双侧肢体筋脉弛缓，痿软无力，处于半瘫痪状态，生活需要家人照顾，病人又诉病发突然但双侧肢体却没有明显疼痛感，随后赴当地中医院，医生通过中医证候分类确诊为其属痿症，医院后采用中医常规治疗，一周后症状不见好转。随后给予本发明中药治疗，服用一周后，作相关检查均趋于正常化，痿软无力症状减轻，继续服用两个月后，痿症症状褪去，患者各方面反应良好，尚无复发，并能进行正常工作、生活。
可见，本发明采用科学的配方及适宜的配比，各药物之间相互配合，协同作用，所制成的中药药物能够安全有效治疗痿症。
具体实施方式
为了更好地理解和实施本发明，下面结合具体实施例进一步说明本发明。
具体实施例1
称取：八月札2克、楮实6克、大血藤3克、柳叶2克、漏芦2克、肿节风9克、刺蒺藜6克、白毛夏枯草7克、墨旱莲2克、白蔹5克、秦皮3克、勾儿茶2克、牛肝3克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗痿症。口服，每日分早晚两次服用。
具体实施例2
称取：八月札2克、楮实6克、大血藤3克、柳叶2克、漏芦2克、肿节风9克、刺蒺藜6克、白毛夏枯草7克、墨旱莲2克、白蔹5克、秦皮3克、勾儿茶2克、牛肝3克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，粉碎，即得符合正常成人1天用量的散剂。
用于治疗痿症。口服，每日分早晚两次服用。
具体实施例3
称取：八月札2克、楮实6克、大血藤3克、柳叶2克、漏芦2克、肿节风9克、刺蒺藜6克、白毛夏枯草7克、墨旱莲2克、白蔹5克、秦皮3克、勾儿茶2克、牛肝3克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再加入适量糊精和矫味剂，按照本领域常规工艺制粒，包装，即可制得符合正常成人1天用量的颗粒剂。
用于治疗痿症。口服，每日分早晚两次服用。
Claims (1)
1.一种治疗痿症的中药，其特征在于，由以下重量配比的药材制备而成：八月札2份、楮实6份、大血藤3份、柳叶2份、漏芦2份、肿节风9份、刺蒺藜6份、白毛夏枯草7份、墨旱莲2份、白蔹5份、秦皮3份、勾儿茶2份、牛肝3份。
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