CN104491089A - 一种治疗颈肩腰腿痛的药物组合物 - Google Patents
一种治疗颈肩腰腿痛的药物组合物 Download PDFInfo
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Abstract
本发明公开一种治疗颈肩腰腿痛的药物组合物。该组合物由王不留行、旋复花、旱莲草、肉豆蔻、威灵仙、牵牛子、蓖麻子、蒲公英、合欢皮、决明子、蜈蚣、水蛭、丝瓜络、半枝莲、鸦胆子、骨碎补、白鲜皮、葶苈子、紫河车、菟丝子、羚羊角、苏木、川牛膝和车前子组成。本发明药物组合物按照常规工艺加入常规辅料制成临床接受的胶囊剂、片剂、丸剂、颗粒剂、口服液、贴膏剂、软膏剂、喷雾剂、擦剂或酊剂。本发明药物组合物具有活血化瘀、祛风通络、抗炎和镇痛作用,对治疗风湿、类风湿性关节炎、骨质增生、颈椎病、腰椎病、肩周炎、腰间盘突出、跌打损伤、腰肌劳损或坐骨神经痛效果显著。
Description
技术领域
本发明涉及一种药物组合物,特别是涉及一种治疗颈肩腰腿痛的药物组合物。
背景技术
颈肩腰腿痛属中医痹症范畴,由正气不足,肝肾亏虚,风寒湿邪侵入骨络或跌仆闪挫,伤损骨络,以致气血瘀滞,运行失畅,不通则痛。肝肾亏虚导致汗出腠理疏松,更因汗出入水,寒湿之邪乘虚入侵,影响气血运行,故周身关节疼痛。“肾主藏精,主骨生髓”,若肾精充足则机体强健,骨骼外形及内部结构正常,且可耐劳累及一般伤损。而“肝主藏血,主筋束骨利关节”,肝血充足则筋脉强劲,静可保护诸骨,充养骨髓;动则约束诸骨,免致过度活动,防止脱位。若肾精亏虚,肝血不足,则骨髓发育异常,更兼筋肉不坚,荣养乏源,既无力保护骨髓、充养骨髓,又不能约束诸骨,防止脱位。目前市场上用于治疗颈肩腰腿痛的药物品种类繁多,西药副作用大,中药效果并不太显著。
发明内容
本发明目的在于提供一种治疗颈肩腰腿痛的药物组合物。
本发明是通过如下技术方案实现的:
本发明药物组合物的原料药组成为:
本发明药物组合物的原料药组成优选为:
本发明药物组合物的原料药组成优选为:
本发明药物组合物的原料药组成优选为:
本发明药物组合物按照常规工艺加入常规辅料制成临床接受的胶囊剂、片剂、丸剂、颗粒剂、口服液、贴膏剂、软膏剂、喷雾剂、擦剂或酊剂。
本发明药物组合物具有活血化瘀、祛风通络、抗炎和镇痛作用,对治疗风湿、类风湿性关节炎、骨质增生、颈椎病、腰椎病、肩周炎、腰间盘突出、跌打损伤、腰肌劳损或坐骨神经痛效果显著。
下面实验例用于进一步说明本发明,但不限于本发明。
实验例一:临床试验
1、临床观察
本发明胶囊剂(按照实施例1方法制备)对治疗颈肩腰腿痛患者100例,其中男性50例,女性50例。
2、药物选择
治疗组选本发明胶囊剂(按照实施例1方法制备),二个疗程(10天一疗程),0.5g/粒,一日三次,每次2粒。
3、诊断标准
①持续性疼痛,疼痛成了生活的一部分。
②活动稍多甚至弯腰拾物、打喷嚏时便发病,疼痛难忍,功能受限。
③阴雨天或受风着凉可引起疼痛的复发或加重。
4、疗效标准
参照国家中医药管理局1994年实施的《中医病诊断疗效标准》拟定如下:
临床痊愈:中医临床症状、体征消失或基本消失;
显效:中医临床症状、体征明显改变;
有效:中医临床症状、体征均有好转;
无效:中医临床症状、体征均无明显改善;
5、治疗结果
组别 | 治疗人数 | 治愈 | 显效 | 有效 | 无效 | 总有效率 |
治疗组 | 100 | 75 | 15 | 9 | 1 | 99% |
6、结论
100例患者服用本发明胶囊剂二个疗程(每个疗程10天),治疗结果显示,总有效率为99%。
实验例二:典型病例
病例1:王某,男,61岁。症状:患者左腿踝关节,疼痛肿胀,行走不便,因劳动病情加重,经诊断确诊为风湿病。通过服用本发明胶囊剂(按照实施例1方法制备,一日三次,每次2粒。)一个疗程(一疗程10天),关节肿痛明显好转,左踝关节功能明显改善,患者可正常行走,继续服用本发明胶囊剂一个疗程,经检查已基本恢复正常。
病例2:李某某,女,58岁。症状:患颈椎病(神经根型)1月余。颈椎疼痛,放射至左侧肩臂膀疼痛难忍、左手大拇指麻木,夜不能眠、害怕晚上睡觉。通过使用本发明贴膏剂(按照实施例2方法制备)治疗三天后见效,晚上疼痛减轻,继续使用7天后疼痛基本减轻。巩固使用10天后,彻底治愈。
病例3:赵某某,男,65岁。症状:腰椎间盘突出,椎管狭窄。腰椎间盘突出L4-5\L5-S1、椎管狭窄,因右下肢疼痛、右足麻木数月,走不能走远,走一段距离(10多米)后下肢出现麻木、疼痛、无力、加重而无法行走,间断休息(下蹲或弯腰一会)后症状减轻或消失,继续行走后又反复出现这种临床症状。牵引按摩、外贴风湿膏治疗无效,口服药物不见好转。来诊时查腰L4、5椎棘突旁右侧压疼明显并向右下肢放射。直腿抬高30度,腰椎活动受限,右足肌力减弱,膝腱反射良好。通过服用本发明丸剂(按照实施例3方法制备)治疗一个疗程后(每个疗程10天),疼痛减轻,继续治疗一个疗程后,上述症状完全消失,痊愈。随访1年无复发。
病例4:周某,女,58岁。症状:肩周炎。患者4年前偶受风寒,右肩患上了肩周炎,昼夜疼痛难忍,肌肉无力、活动障碍。刀割样持久性疼痛。疼痛呈游走性,时而是手掌,时而是肩膀。通过使用本发明软膏剂(按照实施例4方法制备)治疗一个疗程后(每个疗程10天),疼痛明显减轻。继续治疗一个疗程,疼痛症状完全消除,肩部和手臂活动自如,彻底治愈。
下述实施例均能实现上述实验例的效果。
具体实施方式
实施例1胶囊剂
上述药物按照常规工艺加入常规辅料制成胶囊剂,0.5g/粒,一日三次,每次2粒。
实施例2贴膏剂
上述药物按照常规工艺加入常规辅料制成贴膏剂。
实施例3丸剂
上述药物按照常规工艺加入常规辅料制成丸剂。
实施例4软膏剂
上述药物按照常规工艺加入常规辅料制成软膏剂。
实施例5片剂
上述药物按照常规工艺加入常规辅料制成片剂。
实施例6喷雾剂
上述药物按照常规工艺加入常规辅料制成喷雾剂。
Claims (6)
1.一种治疗颈肩腰腿痛的药物组合物,其特征在于,该组合物的原料药组成为:
2.如权利要求1所述的药物组合物,其特征在于该组合物的原料药组成为:
3.如权利要求1所述的药物组合物,其特征在于该组合物的原料药组成为:
4.如权利要求1所述的药物组合物,其特征在于该组合物的原料药组成为:
5.如权利要求1-4之一所述的药物组合物,其特征在于该组合物按照常规工艺加入常规辅料制成临床接受的胶囊剂、片剂、丸剂、颗粒剂、口服液、贴膏剂、软膏剂、喷雾剂、擦剂或酊剂。
6.如权利要求1-4之一所述的药物组合物在制备治疗颈肩腰腿痛的药物中的应用。
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