CN104474049A - Traditional Chinese medicine spray and preparation method thereof - Google Patents
Traditional Chinese medicine spray and preparation method thereof Download PDFInfo
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- CN104474049A CN104474049A CN201410697031.7A CN201410697031A CN104474049A CN 104474049 A CN104474049 A CN 104474049A CN 201410697031 A CN201410697031 A CN 201410697031A CN 104474049 A CN104474049 A CN 104474049A
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/12—Aerosols; Foams
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
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- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a traditional Chinese medicine spray which is prepared from the following raw materials: barks of fresh moringa tree roots, leaves of moringa oleifera, armadillidiam vulgare, radix aconiti agrestis, radix aconiti carmichaeli, flos carthami, lushan mountain barberry roots, nettle roots and borneol. The invention also discloses a preparation method of the traditional Chinese medicine spray. The various raw materials of the traditional Chinese medicine spray achieve a synergistic effect, and the prepared traditional Chinese medicine spray has the effects of quickening blood and dissipating stasis, decreasing swellings and relieving pain, relieving rigidity of muscles and activating collaterals, and has a good treatment effect on rheumatism diseases; and the spray also can be applied to the treatment of various soft tissue injuries such as sprain, bruising and swelling and pain.
Description
Technical field
The invention belongs to field of traditional Chinese, particularly relating to a kind ofly has the Traditional Chinese medicinal spray of good therapeutic effect and the preparation method of this Traditional Chinese medicinal spray to rheumatism.
Background technology
Rheumatalgia refers to mainly to invade joint, muscle, the locality caused by disease of skeleton and periarticular soft tissue (position such as tendon, ligament, synovial bursa, fascia) or systemic pain.Its disease belongs to paralysis one class, and the traditional Chinese medical science thinks wind and the disease caused by wet two kinds of pathogenic factor combination.Disease opinion has headache, heating, slight perspiration, aversion to wind, heavy sensation of the body, dysuria, joint to ache, can not bend and stretch.Arthropathy is outer still with swelling and moving obstacle apart from pain, in outbreak with the alleviation chronic course of disease alternately.Because the blood circulation of patient is obstructed, cause muscle or the nutrition required for tissue cannot be carried by blood circulation, cause that patient muscle lacks nutrition and accelerated ageing becomes stiff, serious meeting causes patient muscle and blood vessel die back, some patients and can occur disabling and viscera function exhaustion in joint.
The existing various medicines for rheumatalgia, but the defect such as it is long all to there is the medication cycle, and curative effect is not obvious, bring great misery to patient.
Summary of the invention
The object of the present invention is to provide a kind of Traditional Chinese medicinal spray with and preparation method thereof, this Traditional Chinese medicinal spray has good therapeutic effect to rheumatism.
On the one hand, the invention provides a kind of Traditional Chinese medicinal spray, be made up of following raw material: skin, leaf of Moringa, Armadillidium, Radix Aconiti Kusnezoffii, Radix Aconiti Lateralis Preparata, Flos Carthami, Berberis soulieana Schaeid, Radix Urticae Cannabinae and the Borneolum Syntheticum of fresh Moringa tree root.
On the other hand, the invention provides a kind of preparation method of Traditional Chinese medicinal spray, comprise the steps:
Material preparation step: prepare following raw material A and raw material B, wherein, the weight proportion of raw material A is: skin 50-75 part of fresh Moringa tree root, leaf of Moringa 10-30 part, Armadillidium 5-20 part; The weight proportion of raw material B is: Radix Aconiti Kusnezoffii 5-20 part, Radix Aconiti Lateralis Preparata 10-30 part, Flos Carthami 15-50 part, Berberis soulieana Schaeid 10-30 part, Radix Urticae Cannabinae 10-30 part;
Aqueous extraction step: described raw material A is placed in water and soaks 150-200 minute, filters to obtain A filtrate;
Alcohol extraction step: described raw material B is placed in ethanol sealing and soaks 20-35 days, filter to obtain B filtrate;
Blend step: by described A filtrate and B filtrate according to the volume ratio mix homogeneously of 60-75:25-40, obtain initial mixing liquid;
Borneolum Syntheticum adds step: in described initial mixing liquid, add Borneolum Syntheticum, forms mixed liquor and mixed liquor is loaded spray bottle after Borneolum Syntheticum dissolves.
Alternatively, preparation in accordance with the present invention, the weight proportion of described raw material A is: the skin of Moringa tree root 65 parts, leaf of Moringa 25 parts, Armadillidium 10 parts; The weight proportion of raw material B is: Radix Aconiti Kusnezoffii 12 parts, Radix Aconiti Lateralis Preparata 20 parts, 35 parts, Flos Carthami, Berberis soulieana Schaeid 17 parts, Radix Urticae Cannabinae 16 parts.
Alternatively, preparation in accordance with the present invention, in described aqueous extraction step, the consumption of described water is 6-10 times of described raw material A weight.
Alternatively, preparation in accordance with the present invention, described aqueous extraction step carries out at 80-90 DEG C.
Alternatively, preparation in accordance with the present invention, in described alcohol extraction step, the consumption of described ethanol is 4-8 times of described raw material B weight.
Alternatively, preparation in accordance with the present invention, in described alcohol extraction step, described ethanol is the ethanol of 80-90vol%.
Alternatively, preparation in accordance with the present invention, adds in step at described Borneolum Syntheticum, and the addition of described Borneolum Syntheticum is the 2-10% of described initial mixing liquid weight.
Alternatively, preparation in accordance with the present invention, described leaf of Moringa is the leaf of Moringa of 6-8 maturation.
In above-mentioned raw material of Chinese medicine, effect of each medical material respectively:
Moringa, set also known as drumstick, Wasabia japonic (Euterma Wasabi) is set, belong to Moringa tree section, for perennial evergreen dungarunga is to megaphanerophyte, its nature and flavor are pungent, tepor, nontoxic, according to the record of " Indian medicinal plant encyclopedia ", Moringa each position except seed has urges wish, spasmolytic, anthelmintic, antiinflammatory, excited, heart tonifying, blood circulation promoting, diuresis, prevention calculus, drive away intestinal parasite, dispel the wind and digestive effect, therefore be used to treat apoplexy, depressed, facial palsy, intestinal colic, calculus of urethra, diabetes, epilepsy, hysteria, gout, lumbago, rheumatism, dermatosis, spleen and liver enlargement and tumor, ulcer, animal bite and ophthalmic.In the present invention, employing be skin and the leaf of Moringa of fresh Moringa tree root.
Armadillidium, the dry polypide of armadillidum vulgare section animal armadillidum vulgare Armadillidium vulgare (Latreille) or Armadillidium Porcellio scaber Latreille; Nature and flavor are sour, salty, cool in nature, return liver, kidney channel; Removing blood stasis with potent drugs eliminating mass, stimulate the menstrual flow, diuretic, removing toxic substances, pain relieving, primary symptom abdominal mass, malaria with splenomegaly, blood stasis amenorrhea, urinary obstruction, infantile convulsion locked jaw, dental pain, all skin ulcers of thrush.
Radix Aconiti Kusnezoffii, the dried root of ranunculaceae plant Aconitum kusnezoffii Reichb Aconitum kusnezoffii Reichb.; Nature and flavor are pungent, bitter, heat; Very toxic, GUIXIN, liver,kidney,spleen warp; Expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, narcotic analgesic.
Flos Carthami, the dried floral of feverfew Flos Carthami Carthamus tinctorius L.; Nature and flavor are pungent, temperature, GUIXIN, Liver Channel; Promoting blood circulation to restore menstrual flow, eliminating stasis to stop pain, for amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, injury from falling down, skin infection swells and ache.
Radix Aconiti Lateralis Preparata, the processed goods of the daughter root of ranunculaceae plant Aconitum carmichjaelii Debx. Aconitum carmichaeli Debx.; Nature and flavor are pungent, sweet, hot greatly; Poisonous, GUIXIN, kidney, spleen channel; Recuperating depleted YANG and rescuing the patient from collapse, mends fire supporing yang, and by wind-cold damp pathogen, for YANG-depletion collapse, cold extremities faint pulse, sexual impotence, cold womb, trusted subordinate's cold type of pain, deficiency and coldness is vomited and diarrhoea, YIN-cold edema, yang deficiency diseases caused by exogenous pathogenic factor, arthralgia due to cold-dampnes.
Radix Berberidis soulieanae, the root of the yellow leaf Mahonia fortunei (Lindl.) Fedde of Berberidaceae plant, west place in Hubei Mahonia fortunei (Lindl.) Fedde and Mengzi Mahonia fortunei (Lindl.) Fedde and stem; Nature and flavor are bitter; Tremble with fear and return liver, stomach warp; Heat-clearing and toxic substances removing; Preventing phlegm from forming and stopping coughing, main cold, fever, laryngopharynx swelling and pain, enteritis, dysentery, jaundice, hypertension, consumptive disease loudspeaker spitting of blood, traumatic injury, toothache.
Radix Urticae Cannabinae, the root of contrayerva fiber crops urtica angustifolia, Folium Cannabis Herba Urticae Cannabinae etc.; Nature and flavor are bitter, pungent, warm in nature, slightly poisonous; Dispel the wind, invigorate blood circulation, pain relieving, main rheumatalgia, urticaria, eczema, hypertension.
Borneolum Syntheticum, the processed goods of Spore density Borneolum Syntheticum resin, or the product of being processed into chemically synthesized for Camphora, Lignum Pini Nodi wet goods; Nature and flavor are pungent, bitter, are slightly cold, GUIXIN, spleen, lung meridian; Have one's ideas straightened out refreshment, clearing away heat to alleviate pain, faints for calentura coma, convulsion, apoplexy syncope due to accumulation of phlegm, stagnation of QI sudden syncope, and attacked by pestiferous factors is gone into a coma, and conjunctival congestion, aphtha, laryngopharynx swelling and pain, auditory meatus is suppurated.
Traditional Chinese medicinal spray of the present invention is with above-mentioned several kinds of Chinese medicinal materials for raw material, and play synergism, obtained Traditional Chinese medicinal spray has promoting blood circulation to remove blood stasis, reducing swelling and alleviating pain, effect of relaxing muscles and tendons and activating QI and blood in the collateral, good to the therapeutic effect of rheumatism, also can be used for various soft tissue injurys such as spraining, congestion swells and ache.
Accompanying drawing explanation
By reading hereafter detailed description of the preferred embodiment, various other advantage and benefit will become cheer and bright for those of ordinary skill in the art.Accompanying drawing only for illustrating the object of preferred implementation, and does not think limitation of the present invention.In the accompanying drawings:
Fig. 1 is the schematic flow sheet of Traditional Chinese medicinal spray preparation method of the present invention.
Detailed description of the invention
The invention provides many applicable creative concepts, this creative concept can be reflected in a large number of in concrete context.The specific embodiment described in following embodiments of the present invention only as the exemplary illustration of the specific embodiment of the present invention, and does not form limitation of the scope of the invention.
Below in conjunction with concrete embodiment, the invention will be further described.
On the one hand, the invention provides a kind of Traditional Chinese medicinal spray, be made up of following raw material: skin, leaf of Moringa, Armadillidium, Radix Aconiti Kusnezoffii, Radix Aconiti Lateralis Preparata, Flos Carthami, Berberis soulieana Schaeid, Radix Urticae Cannabinae and the Borneolum Syntheticum of fresh Moringa tree root.
On the other hand, the invention provides the preparation method of above-mentioned Traditional Chinese medicinal spray, Fig. 1 shows the schematic flow sheet of Traditional Chinese medicinal spray preparation method of the present invention.As shown in Figure 1, the method comprises the steps:
Material preparation step S1100: prepare following raw material A and raw material B, wherein, the weight proportion of raw material A is: skin 50-75 part of fresh Moringa tree root, leaf of Moringa 10-30 part, Armadillidium 5-20 part; The weight proportion of raw material B is: Radix Aconiti Kusnezoffii 5-20 part, Radix Aconiti Lateralis Preparata 10-30 part, Flos Carthami 15-50 part, Berberis soulieana Schaeid 10-30 part, Radix Urticae Cannabinae 10-30 part;
Aqueous extraction step S1200: described raw material A is placed in water and soaks 150-200 minute, filters to obtain A filtrate;
Alcohol extraction step S1300: described raw material B is placed in ethanol sealing and soaks 20-35 days, filter to obtain B filtrate;
Blend step S1400: by described A filtrate and B filtrate according to the volume ratio mix homogeneously of 60-75:25-40, obtain initial mixing liquid;
Borneolum Syntheticum adds step S1500: in described initial mixing liquid, add Borneolum Syntheticum, forms mixed liquor and mixed liquor is loaded spray bottle after Borneolum Syntheticum dissolves.
Wherein, in described material preparation step S1100, the weight proportion of described raw material A is: the skin of Moringa tree root 65 parts, leaf of Moringa 25 parts, Armadillidium 10 parts; The weight proportion of raw material B is: Radix Aconiti Kusnezoffii 12 parts, Radix Aconiti Lateralis Preparata 20 parts, 35 parts, Flos Carthami, Berberis soulieana Schaeid 17 parts, Radix Urticae Cannabinae 16 parts.
In described aqueous extraction step S1200, the consumption of described water is preferably the 6-10 of described raw material A weight doubly, is more preferably 8 times; And described aqueous extraction step preferably carries out 180 minutes at 80-90 DEG C.Described aqueous extraction step can carry out once also can carrying out repeatedly, to extract the active substance in raw material more fully.First raw material A can also be soaked 60 minutes in water, and then heating is extracted.
In described alcohol extraction step S1300, preferably use the ethanol of 80-90vol% to soak raw material B, the use amount of described ethanol is 4-8 times of described raw material B gross weight, and more preferably 6 times, soak time is preferably 28 days.Described alcohol extraction step can carry out once also can carrying out repeatedly, to extract the active substance in raw material more fully.
In described blend step S1400, described A filtrate and B filtrate preferably mix according to the volume ratio of 68:32.
Add in step S1500 at described Borneolum Syntheticum, the addition of described Borneolum Syntheticum is the 2-10% of described initial mixing liquid weight, is preferably 5%.
Preparation method of the present invention, the leaf of Moringa that described leaf of Moringa preferably uses Maturity to become for 6-8.
The Traditional Chinese medicinal spray proposed according to the present invention and the optional element of Traditional Chinese medicinal spray preparation method more, various embodiments can be designed, therefore specific embodiment is only as the exemplary illustration of specific implementation of the present invention, and does not form limitation of the scope of the invention.In order to concrete description the present invention, following examples are selected to carry out exemplary illustration.
Embodiment 1
First prepare raw material A and raw material B, wherein, the weight proportion of raw material A is: the skin of fresh Moringa tree root 50 parts, the leaf of Moringa of 8 maturations 30 parts, Armadillidium 20 parts; The weight proportion of raw material B is: Radix Aconiti Kusnezoffii 5 parts, Radix Aconiti Lateralis Preparata 10 parts, 25 parts, Flos Carthami, Berberis soulieana Schaeid 30 parts, Radix Urticae Cannabinae 30 parts.
Described raw material A is placed in weight be raw material A weight 6 times water soak 60 minutes, be then heated to 90 DEG C and extract, extract after 180 minutes, filter to obtain A filtrate.Described raw material B being placed in weight is that the ethanol of raw material B weight 4 times seals immersion 20 days, filters to obtain B filtrate.
By described A filtrate and B filtrate according to the volume ratio mix homogeneously of 60:40, obtain initial mixing liquid.In described initial mixing liquid, add the Borneolum Syntheticum of its weight 8%, after Borneolum Syntheticum dissolves, form mixed liquor, finally mixed liquor being loaded spray bottle can obtain Traditional Chinese medicinal spray.
Embodiment 2
First prepare raw material A and raw material B, wherein, the weight proportion of raw material A is: the skin of fresh Moringa tree root 65 parts, the leaf of Moringa of 8 maturations 25 parts, Armadillidium 10 parts; The weight proportion of raw material B is: Radix Aconiti Kusnezoffii 12 parts, Radix Aconiti Lateralis Preparata 20 parts, 35 parts, Flos Carthami, Berberis soulieana Schaeid 17 parts, Radix Urticae Cannabinae 16 parts.
Described raw material A is placed in weight be raw material A weight 8 times water soak 60 minutes, be then heated to 80 DEG C and extract, extract after 180 minutes, filter to obtain A filtrate.Described raw material B being placed in weight is that the ethanol of raw material B weight 6 times seals immersion 28 days, filters to obtain B filtrate.
By described A filtrate and B filtrate according to the volume ratio mix homogeneously of 68:32, obtain initial mixing liquid.In described initial mixing liquid, add the Borneolum Syntheticum of its weight 5%, after Borneolum Syntheticum dissolves, form mixed liquor, finally mixed liquor being loaded spray bottle can obtain Traditional Chinese medicinal spray.
Embodiment 3
First prepare raw material A and raw material B, wherein, the weight proportion of raw material A is: the skin of fresh Moringa tree root 75 parts, the leaf of Moringa of 6 maturations 10 parts, Armadillidium 15 parts; The weight proportion of raw material B is: Radix Aconiti Kusnezoffii 20 parts, Radix Aconiti Lateralis Preparata 30 parts, 30 parts, Flos Carthami, Berberis soulieana Schaeid 10 parts, Radix Urticae Cannabinae 10 parts.
Described raw material A is placed in weight be raw material A weight 10 times water soak 60 minutes, be then heated to 90 DEG C and extract, extract after 150 minutes, filter to obtain A filtrate.Described raw material B being placed in weight is that the ethanol of raw material B weight 6 times seals immersion 30 days, filters to obtain B filtrate.
By described A filtrate and B filtrate according to the volume ratio mix homogeneously of 75:25, obtain initial mixing liquid.In described initial mixing liquid, add the Borneolum Syntheticum of its weight 10%, after Borneolum Syntheticum dissolves, form mixed liquor, finally mixed liquor being loaded spray bottle can obtain Traditional Chinese medicinal spray.
Embodiment 4
First prepare raw material A and raw material B, wherein, the weight proportion of raw material A is: the skin of fresh Moringa tree root 70 parts, the leaf of Moringa of 7 maturations 25 parts, Armadillidium 5 parts; The weight proportion of raw material B is: Radix Aconiti Kusnezoffii 20 parts, Radix Aconiti Lateralis Preparata 15 parts, 15 parts, Flos Carthami, Berberis soulieana Schaeid 20 parts, Radix Urticae Cannabinae 30 parts.
Described raw material A is placed in weight be raw material A weight 8 times water soak 60 minutes, be then heated to 90 DEG C and extract, extract after 180 minutes, filter to obtain A filtrate.Described raw material B being placed in weight is that the ethanol of raw material B weight 4 times seals immersion 35 days, filters to obtain B filtrate.
By described A filtrate and B filtrate according to the volume ratio mix homogeneously of 70:30, obtain initial mixing liquid.In described initial mixing liquid, add the Borneolum Syntheticum of its weight 5%, after Borneolum Syntheticum dissolves, form mixed liquor, finally mixed liquor being loaded spray bottle can obtain Traditional Chinese medicinal spray.
Embodiment 5
First prepare raw material A and raw material B, wherein, the weight proportion of raw material A is: the skin of fresh Moringa tree root 60 parts, the leaf of Moringa of 8 maturations 20 parts, Armadillidium 20 parts; The weight proportion of raw material B is: Radix Aconiti Kusnezoffii 10 parts, Radix Aconiti Lateralis Preparata 25 parts, 40 parts, Flos Carthami, Berberis soulieana Schaeid 15 parts, Radix Urticae Cannabinae 10 parts.
Described raw material A is placed in weight be raw material A weight 8 times water soak 60 minutes, be then heated to 90 DEG C and extract, extract after 180 minutes, filter to obtain A filtrate.Described raw material B being placed in weight is that the ethanol of raw material B weight 6 times seals immersion 28 days, filters to obtain B filtrate.
By described A filtrate and B filtrate according to the volume ratio mix homogeneously of 65:35, obtain initial mixing liquid.In described initial mixing liquid, add the Borneolum Syntheticum of its weight 5%, after Borneolum Syntheticum dissolves, form mixed liquor, finally mixed liquor being loaded spray bottle can obtain Traditional Chinese medicinal spray.
Comparative example 1
Prepare Traditional Chinese medicinal spray according to the weight proportion identical with embodiment 2 and making step, wherein, difference is, the leaf of Moringa of employing is 5 maturations.
Test case 1-6
Test case 1-6 is used for the effect that the Traditional Chinese medicinal spray treatment rheumatalgia that embodiment of the present invention 1-5 and comparative example 1 provide schematically is described.
Select 300 men and women patients with rheumatalgia in various degree, age of patient 30-65 year between, be divided into 6 groups (often organizing 50 patients) at random.Sprayed coating Chinese medicine preparation 1-6 respectively, morning, noon and afternoon every day each sprayed coating 1 time, covers sufferer place with Traditional Chinese medicinal spray at every turn.Namely obviously what after sprayed coating, half an hour, pain was alleviated is labeled as zero, and what after sprayed coating, 1 hour pain was just slightly alleviated is labeled as △, after sprayed coating 2 hours pain still without being labeled as of obvious alleviation ×; The therapeutic effect of 6 groups is as shown in table 3.
Table 1
As can be seen from the test result of above test case, the Traditional Chinese medicinal spray that embodiment of the present invention 1-5 provides can be better to the curative effect of rheumatalgia, Most patients's pain after spray medicine half an hour can obviously be alleviated, especially best with the therapeutic effect of embodiment 2, therefore this embodiment is most preferred embodiment of the present invention.Meanwhile, as can be seen from the testing result of embodiment 2 and the testing result of comparative example 1, the therapeutic effect tool of Maturity to Traditional Chinese medicinal spray of leaf of Moringa has a certain impact, and when the Maturity of leaf of Moringa is less than 6 one-tenth, the therapeutic effect of Traditional Chinese medicinal spray is just aobvious to decline.
It should be noted, the present invention will be described instead of limit the invention for above-described embodiment, and those skilled in the art can design alternative embodiment when not departing from the scope of claims.In the claims, any reference marks between bracket should be configured to limitations on claims.Word " comprises " not to be got rid of existence and does not arrange element in the claims or step.Word first, second and third-class use do not represent any order, can be title by these word explanations.
Claims (9)
1. a Traditional Chinese medicinal spray, is made up of following raw material: skin, leaf of Moringa, Armadillidium, Radix Aconiti Kusnezoffii, Radix Aconiti Lateralis Preparata, Flos Carthami, Berberis soulieana Schaeid, Radix Urticae Cannabinae and the Borneolum Syntheticum of fresh Moringa tree root.
2. a preparation method for Traditional Chinese medicinal spray according to claim 1, comprises the steps:
Material preparation step: prepare following raw material A and raw material B, wherein, the weight proportion of raw material A is: skin 50-75 part of fresh Moringa tree root, leaf of Moringa 10-30 part, Armadillidium 5-20 part; The weight proportion of raw material B is: Radix Aconiti Kusnezoffii 5-20 part, Radix Aconiti Lateralis Preparata 10-30 part, Flos Carthami 15-50 part, Berberis soulieana Schaeid 10-30 part, Radix Urticae Cannabinae 10-30 part;
Aqueous extraction step: described raw material A is placed in water and soaks 150-200 minute, filters to obtain A filtrate;
Alcohol extraction step: described raw material B is placed in ethanol sealing and soaks 20-35 days, filter to obtain B filtrate;
Blend step: by described A filtrate and B filtrate according to the volume ratio mix homogeneously of 60-75:25-40, obtain initial mixing liquid;
Borneolum Syntheticum adds step: in described initial mixing liquid, add Borneolum Syntheticum, forms mixed liquor and mixed liquor is loaded spray bottle after Borneolum Syntheticum dissolves.
3. preparation method according to claim 2, wherein, the weight proportion of described raw material A is: the skin of Moringa tree root 65 parts, leaf of Moringa 25 parts, Armadillidium 10 parts; The weight proportion of raw material B is: Radix Aconiti Kusnezoffii 12 parts, Radix Aconiti Lateralis Preparata 20 parts, 35 parts, Flos Carthami, Berberis soulieana Schaeid 17 parts, Radix Urticae Cannabinae 16 parts.
4. preparation method according to claim 2, wherein, in described aqueous extraction step, the consumption of described water is 6-10 times of described raw material A weight.
5. preparation method according to claim 2, wherein, described aqueous extraction step carries out at 80-90 DEG C.
6. preparation method according to claim 2, wherein, in described alcohol extraction step, the consumption of described ethanol is 4-8 times of described raw material B weight.
7. preparation method according to claim 2, wherein, in described alcohol extraction step, described ethanol is the ethanol of 80-90vol%.
8. preparation method according to claim 2, wherein, adds in step at described Borneolum Syntheticum, and the addition of described Borneolum Syntheticum is the 2-10% of described initial mixing liquid weight.
9. the preparation method according to any one of claim 2-8, wherein, described leaf of Moringa is the leaf of Moringa of 6-8 maturation.
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| CN113952498B (en) * | 2021-09-28 | 2022-11-29 | 江西中医药大学 | Chinese medicine multi-component liquid wound healing dressing and preparation method thereof |
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