CN104436339A - 无动力性人工心室装置 - Google Patents

无动力性人工心室装置 Download PDF

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Publication number
CN104436339A
CN104436339A CN201310440122.8A CN201310440122A CN104436339A CN 104436339 A CN104436339 A CN 104436339A CN 201310440122 A CN201310440122 A CN 201310440122A CN 104436339 A CN104436339 A CN 104436339A
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China
Prior art keywords
ventricle
artificial
patient
heart
artificial ventricle
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CN201310440122.8A
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Inventor
李温斌
许秀芳
任学军
吴昊
徐志伟
周子凡
裴金凤
张健群
龚达
石秋霞
陈宝田
周其文
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/10—Location thereof with respect to the patient's body
    • A61M60/122—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body
    • A61M60/126—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel
    • A61M60/148—Implantable pumps or pumping devices, i.e. the blood being pumped inside the patient's body implantable via, into, inside, in line, branching on, or around a blood vessel in line with a blood vessel using resection or like techniques, e.g. permanent endovascular heart assist devices
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M60/00—Blood pumps; Devices for mechanical circulatory actuation; Balloon pumps for circulatory assistance
    • A61M60/20—Type thereof
    • A61M60/247—Positive displacement blood pumps
    • A61M60/253—Positive displacement blood pumps including a displacement member directly acting on the blood
    • A61M60/268—Positive displacement blood pumps including a displacement member directly acting on the blood the displacement member being flexible, e.g. membranes, diaphragms or bladders

Abstract

技术领域医学，组织工程学；发明内容设计并制作了“无动力人性工心室装置”。制作方法：按附图方法缝制一种无动力人工心室，该装置由一个囊腔和二个开口组成，囊的容积为正常左或右心室容积的大小；两开口分别位于囊的两端，分别为含有人工心脏瓣膜的入口和出口。应用方法及效果：将人工心室置于单心室患者的单心室腔内，其入口与患者的三(二)尖瓣环连接，出口与患者的肺动脉瓣环(主动脉瓣环)连接。如此形成的心脏结构可将患者的动、静脉血液切开，以根治单心室病变。工作原理：人工心室容纳静脉血(或动脉血)，起到右(左)心脏的功能，而单心室腔仅接受动脉(或静脉)血液，起到左(右)心室的功能。人工心室依赖患者自身单心室动力工作。

Description

无动力性人工心室装置
技术领域医学，组织工程学。 
背景技术水生动物进化到陆生动物见证了循环系统由简单向复杂迈进的过程。鱼类只有单心房单心室，单一的血液循环途径，两栖类除了鳄鱼，心脏已演变为双心房和分割不完全的单心室，两条循环途径。而哺乳动物心脏具有完整的双心房和双心室，两个心室均呈现并列排列的结构关系，均相对独立的工作，动、静脉血完全分开，具有体、肺两条血液循环路线，分别与体、肺循环系统相连接，心脏的双心室同步收缩与舒张，两心室即相互依赖，又各自相对独立地工作。但是，至今自然界从没有发现这样一种心脏结构关系，即一个心室位于另一个心室当中，二者呈现包含与被包含的寄生性心室结构，并且一个心室无动力特性，它的收缩与舒张有赖于另一心室的动力。目前这种心脏结构在自然界是不存在的。 
发明内容设计并制作了“无动力性人工心室装置”。该装置可以用来治疗单心室患者和为设计新型人工心脏提供新的思路。 
附图说明
图1：无动力性人工心室装置切面图；
图2：无动力性人工心室装置的效果图；
图3：无动力性人工心室装置放入单心室腔内的效果图 
具体实施方式按照预先设计方案，应用生物材料(包括牛心包膜、自体心包膜以及组织工程心包膜等)人工缝制(应用各种无创缝线)一种无动力的人工心室，我们将其称为“无动力性人工心室装置”(见附图)。设计方案：无动力性人工心室装置由一个囊腔和二个开口组成，囊的容积为正常左或右心室容积的大小，50-100m，由两张牛心包缝制而成，其形状与正常人体右心室相似，两开口分别位于囊的两端，分别为入口和出口，并在出入口处人工缝合方法分别置入一枚人工心脏瓣膜(包括人工生物瓣或机械瓣或组织工程瓣)瓣口直径20-30mm。无动力性人工心室装置的应用方法及效果：在全身麻醉和体外循环下，手术中打开胸腔，在心脏停跳下切开心脏，将无动力性人工心室装置置于先天性心脏病单心室患者的单心室腔内，其入口与患者的三(二)尖瓣环连接，出口与患者的肺动脉瓣环(主动脉瓣环)连接，将其囊腔部分置业入患者的单心室腔内，如此形成的心脏结构可将患者的动静脉血液在新的两腔心室内分开，起到正常人的心脏功能，形成动、静脉两条血液循环回路，以根治单心室病变。无动力人性工心室装置的工作原理：无动力人性工心室的入口借助于人工三(二)尖瓣连接于三(二)尖瓣环，出口直接或借人工生物瓣连接于主肺动脉瓣环或主动脉瓣环上，从而将该右(左)心室与肺(体)循环连接。人工心室容纳静脉血(或动脉血)，并将其射 入肺(主)动脉内，并依靠单心室的收缩舒张功能来工作，从而起到右(左)心脏的功能，而单心室腔仅接受动脉(或静脉)血液，并将其射入主(肺)动脉内，起到左(右)心室的功能。二者呈包含与被包含关系，该人工心室与单心室腔呈包含与被包含关系，且无动力性人工心室装置依赖患者自身单心室动力工作。 

Claims (3)

  1. 该项申请的无动力人工心室装置专利，其人工心室是应用生物材料按正常人心脏左或右心室的形态及大小制作的，其制作方法简单，多样，但应用价值大，故要求以下专利权：
    1.人工心室的结构特征，包括：
    1).带各种人工心脏瓣膜(包括人工生物瓣或机械瓣或组织工程瓣)的无动力性人工心室装置以及只在入口处安装人工心脏瓣膜的无动力人工心室装置。
    2).心室囊的结构多样性，如心形，梨形，梭形，球形等。
    3).心室囊制作材料的多样性，如自体心包，组织工程心包等。
  2. 2.人工心室的制作方法，包括人工缝制，机械缝制，机械压制等。
  3. 3.人工心室的用途，如治疗单心室病变，用于研制该类似结构的人工心脏或心室辅助装置等。
CN201310440122.8A 2013-09-25 2013-09-25 无动力性人工心室装置 Pending CN104436339A (zh)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648690A (zh) * 2016-07-26 2018-02-02 广东省心血管病研究所 腔肺辅助循环装置
CN109420206A (zh) * 2017-08-29 2019-03-05 李温斌 无动力性人工心室装置

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0324669A1 (fr) * 1988-01-14 1989-07-19 Universite Pierre Et Marie Curie Paris Vi Prothèse cardiaque totalement implantable à membranes flottantes, à raccord rapide et à éléments sensibles amovibles
WO1992020303A1 (en) * 1991-05-16 1992-11-26 Mures Cardiovascular Research, Inc. Cardiac valve
CN1279114A (zh) * 1999-06-28 2001-01-10 山东省千佛山医院 一种人工心脏瓣膜生物材料的加工方法
WO2005084224A2 (en) * 2004-02-27 2005-09-15 Ep Medsystems, Inc. Methods and systems for ultrasound imaging of the heart from the pericardium
CN1785136A (zh) * 2004-12-09 2006-06-14 解启莲 永久植入性心腔内仿生心脏
CN1806774A (zh) * 2005-01-19 2006-07-26 百奥阿提斯有限公司 人工血管支架和人工器官
CN101472629A (zh) * 2006-06-15 2009-07-01 道达尔卡朋特马塔卡玛人造心脏集团 可移植在解剖位置中的整体式心脏假体

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0324669A1 (fr) * 1988-01-14 1989-07-19 Universite Pierre Et Marie Curie Paris Vi Prothèse cardiaque totalement implantable à membranes flottantes, à raccord rapide et à éléments sensibles amovibles
WO1992020303A1 (en) * 1991-05-16 1992-11-26 Mures Cardiovascular Research, Inc. Cardiac valve
CN1279114A (zh) * 1999-06-28 2001-01-10 山东省千佛山医院 一种人工心脏瓣膜生物材料的加工方法
WO2005084224A2 (en) * 2004-02-27 2005-09-15 Ep Medsystems, Inc. Methods and systems for ultrasound imaging of the heart from the pericardium
CN1785136A (zh) * 2004-12-09 2006-06-14 解启莲 永久植入性心腔内仿生心脏
CN1806774A (zh) * 2005-01-19 2006-07-26 百奥阿提斯有限公司 人工血管支架和人工器官
CN101472629A (zh) * 2006-06-15 2009-07-01 道达尔卡朋特马塔卡玛人造心脏集团 可移植在解剖位置中的整体式心脏假体

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107648690A (zh) * 2016-07-26 2018-02-02 广东省心血管病研究所 腔肺辅助循环装置
CN109420206A (zh) * 2017-08-29 2019-03-05 李温斌 无动力性人工心室装置

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