CN104436288A - 一种复合医用水凝胶敷料材料及其制备方法 - Google Patents
一种复合医用水凝胶敷料材料及其制备方法 Download PDFInfo
- Publication number
- CN104436288A CN104436288A CN201410626766.0A CN201410626766A CN104436288A CN 104436288 A CN104436288 A CN 104436288A CN 201410626766 A CN201410626766 A CN 201410626766A CN 104436288 A CN104436288 A CN 104436288A
- Authority
- CN
- China
- Prior art keywords
- dressing material
- aerogel dressing
- preparation
- composite medical
- alginic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000000463 material Substances 0.000 title claims abstract description 76
- 239000002131 composite material Substances 0.000 title claims abstract description 38
- 238000002360 preparation method Methods 0.000 title claims abstract description 36
- 239000000017 hydrogel Substances 0.000 title claims abstract description 32
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims abstract description 75
- 239000000783 alginic acid Substances 0.000 claims abstract description 47
- 235000010443 alginic acid Nutrition 0.000 claims abstract description 47
- 229920000615 alginic acid Polymers 0.000 claims abstract description 47
- 229960001126 alginic acid Drugs 0.000 claims abstract description 47
- 150000004781 alginic acids Chemical class 0.000 claims abstract description 47
- 229920000159 gelatin Polymers 0.000 claims abstract description 47
- 235000019322 gelatine Nutrition 0.000 claims abstract description 47
- 108010010803 Gelatin Proteins 0.000 claims abstract description 42
- 239000008273 gelatin Substances 0.000 claims abstract description 42
- 235000011852 gelatine desserts Nutrition 0.000 claims abstract description 42
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 41
- 239000004372 Polyvinyl alcohol Substances 0.000 claims abstract description 31
- 229920002451 polyvinyl alcohol Polymers 0.000 claims abstract description 31
- 238000003756 stirring Methods 0.000 claims abstract description 9
- 239000004964 aerogel Substances 0.000 claims description 52
- -1 Hydroxypropyl Chemical group 0.000 claims description 24
- 238000013019 agitation Methods 0.000 claims description 24
- 230000006641 stabilisation Effects 0.000 claims description 9
- 238000011105 stabilization Methods 0.000 claims description 9
- 239000001828 Gelatine Substances 0.000 claims description 5
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 abstract 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 abstract 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 abstract 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 abstract 2
- 238000001816 cooling Methods 0.000 abstract 1
- 239000008367 deionised water Substances 0.000 abstract 1
- 229910021641 deionized water Inorganic materials 0.000 abstract 1
- 239000012567 medical material Substances 0.000 abstract 1
- 230000000630 rising effect Effects 0.000 abstract 1
- 238000010521 absorption reaction Methods 0.000 description 7
- 230000000052 comparative effect Effects 0.000 description 6
- 108010025899 gelatin film Proteins 0.000 description 5
- 239000000499 gel Substances 0.000 description 4
- 238000001035 drying Methods 0.000 description 2
- 229920002521 macromolecule Polymers 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 206010070834 Sensitisation Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 238000010382 chemical cross-linking Methods 0.000 description 1
- 229920006037 cross link polymer Polymers 0.000 description 1
- 238000004132 cross linking Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 125000001165 hydrophobic group Chemical group 0.000 description 1
- 230000014759 maintenance of location Effects 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 239000003883 ointment base Substances 0.000 description 1
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000002861 polymer material Substances 0.000 description 1
- 235000019422 polyvinyl alcohol Nutrition 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000008313 sensitization Effects 0.000 description 1
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 description 1
- 238000001291 vacuum drying Methods 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Materials For Medical Uses (AREA)
Abstract
Description
Claims (10)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410626766.0A CN104436288B (zh) | 2014-11-10 | 2014-11-10 | 一种复合医用水凝胶敷料材料及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201410626766.0A CN104436288B (zh) | 2014-11-10 | 2014-11-10 | 一种复合医用水凝胶敷料材料及其制备方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN104436288A true CN104436288A (zh) | 2015-03-25 |
CN104436288B CN104436288B (zh) | 2017-02-08 |
Family
ID=52883539
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201410626766.0A Expired - Fee Related CN104436288B (zh) | 2014-11-10 | 2014-11-10 | 一种复合医用水凝胶敷料材料及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN104436288B (zh) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106362201A (zh) * | 2016-08-29 | 2017-02-01 | 桂林新艺制冷设备有限责任公司 | 一种医用水凝胶敷料材料 |
CN107456602A (zh) * | 2017-08-04 | 2017-12-12 | 北京化工大学常州先进材料研究院 | 一种全生物可降解短纤增强的医用水凝胶体敷料及其制备方法 |
CN115138345A (zh) * | 2022-07-13 | 2022-10-04 | 青岛科技大学 | 一种水凝胶微珠制剂、其制备方法及应用 |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1616116A (zh) * | 2004-09-29 | 2005-05-18 | 杭州拜康医用产品有限公司 | 含有辐照敏感剂的水凝胶创伤敷料及制备方法 |
CN101316618A (zh) * | 2005-11-14 | 2008-12-03 | 株式会社大熊 | 包含表皮生长因子的用于愈合伤口的缓释膜剂 |
CN101524545A (zh) * | 2008-03-07 | 2009-09-09 | 大连永兴生物医药孵化器有限公司 | 一种止血凝胶栓剂 |
KR20130006834A (ko) * | 2011-06-24 | 2013-01-18 | 주식회사 바이오알파 | 피부 및 상처 보호를 위한 실크 필름의 제조방법 |
CN103083713A (zh) * | 2012-12-10 | 2013-05-08 | 江苏华亿细胞组织工程有限公司 | 一种无菌聚合创面覆盖物敷料 |
-
2014
- 2014-11-10 CN CN201410626766.0A patent/CN104436288B/zh not_active Expired - Fee Related
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1616116A (zh) * | 2004-09-29 | 2005-05-18 | 杭州拜康医用产品有限公司 | 含有辐照敏感剂的水凝胶创伤敷料及制备方法 |
CN101316618A (zh) * | 2005-11-14 | 2008-12-03 | 株式会社大熊 | 包含表皮生长因子的用于愈合伤口的缓释膜剂 |
CN101524545A (zh) * | 2008-03-07 | 2009-09-09 | 大连永兴生物医药孵化器有限公司 | 一种止血凝胶栓剂 |
KR20130006834A (ko) * | 2011-06-24 | 2013-01-18 | 주식회사 바이오알파 | 피부 및 상처 보호를 위한 실크 필름의 제조방법 |
CN103083713A (zh) * | 2012-12-10 | 2013-05-08 | 江苏华亿细胞组织工程有限公司 | 一种无菌聚合创面覆盖物敷料 |
Non-Patent Citations (1)
Title |
---|
丁晔等: "壳聚糖复合海绵材料的制备及性能", 《中国医药工业杂志》 * |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106362201A (zh) * | 2016-08-29 | 2017-02-01 | 桂林新艺制冷设备有限责任公司 | 一种医用水凝胶敷料材料 |
CN107456602A (zh) * | 2017-08-04 | 2017-12-12 | 北京化工大学常州先进材料研究院 | 一种全生物可降解短纤增强的医用水凝胶体敷料及其制备方法 |
CN115138345A (zh) * | 2022-07-13 | 2022-10-04 | 青岛科技大学 | 一种水凝胶微珠制剂、其制备方法及应用 |
CN115138345B (zh) * | 2022-07-13 | 2023-10-20 | 青岛科技大学 | 一种水凝胶微珠制剂、其制备方法及应用 |
Also Published As
Publication number | Publication date |
---|---|
CN104436288B (zh) | 2017-02-08 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Fahmy et al. | К‐carrageenan/Na‐alginate wound dressing with sustainable drug delivery properties | |
JP5503888B2 (ja) | 化粧品パック用ゲルシート | |
CN103520767B (zh) | 一种抗菌促愈水凝胶敷料及其制备方法 | |
Duquette et al. | Comparative studies of chemical crosslinking reactions and applications of bio-based hydrogels | |
CN102764447B (zh) | 水凝胶敷料及其制备工艺 | |
CN103494668B (zh) | 医用水凝胶保湿护眼贴及其制备方法 | |
Sadeghi | Synthesis of a biocopolymer carrageenan-g-poly (AAm-co-IA)/montmorilonite superabsorbent hydrogel composite | |
Pandey et al. | Microwaved bacterial cellulose-based hydrogel microparticles for the healing of partial thickness burn wounds | |
Islan et al. | Studies of ciprofloxacin encapsulation on alginate/pectin matrixes and its relationship with biodisponibility | |
CN104436288B (zh) | 一种复合医用水凝胶敷料材料及其制备方法 | |
US20210207098A1 (en) | Drying formulation for hydrogel microcarriers | |
CN106474523A (zh) | 基于羧甲基壳聚糖的聚电解质海绵创伤敷料的制备方法 | |
CN103113600A (zh) | 一种光响应可逆壳聚糖水凝胶及其制备方法 | |
CN104987816B (zh) | 一种多功能乳胶漆配方及其生产方法 | |
CN105936674A (zh) | 一种紫外光3d打印用海藻酸水凝胶基质的制备方法 | |
CN104262880B (zh) | 一种高强度抑菌纳米复合阳离子双网络水凝胶及其制备方法 | |
CN104353105A (zh) | 一种医用纳米抗菌凝胶材料及其制备方法 | |
Zhou et al. | Effect of metal ions with reducing properties on hydrogels containing catechol groups | |
Nath et al. | Multifunctional mussel‐inspired Gelatin and Tannic acid‐based hydrogel with pH‐controllable release of vitamin B12 | |
CN107955188B (zh) | 一种改性羟乙基纤维素超吸水凝胶及其制备方法和应用 | |
Mali et al. | Synthesis and characterization of citric acid crosslinked carboxymethyl tamarind gum-polyvinyl alcohol hydrogel films | |
Sun et al. | Chitosan-based supramolecular aerogel with “skeletal structure” constructed in natural deep eutectic solvents for medical dressings | |
CN104403249A (zh) | 一种抗菌性高吸水树脂的制备方法 | |
Sun et al. | Construction of chitosan-based supramolecular biofilm material for wound dressing based on natural deep eutectic solvents | |
CN109880218B (zh) | 一种水发泡抗菌透气微孔薄膜母料、薄膜及制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
C41 | Transfer of patent application or patent right or utility model | ||
CB03 | Change of inventor or designer information |
Inventor after: Wu Zhenbiao Inventor after: Quan Chunlan Inventor after: Zhang Fan Inventor before: Jin Zhongen Inventor before: Quan Chunlan Inventor before: Zhang Fan |
|
COR | Change of bibliographic data | ||
TA01 | Transfer of patent application right |
Effective date of registration: 20160928 Address after: 362300 Fujian city of Quanzhou province Nanan kangmeikang beauty Development Zone Applicant after: NAN'AN YONGTENG TECHNOLOGY CONSULTATION Co.,Ltd. Address before: 215163 Suzhou province high tech Zone Longshan Road, No. 10, Jiangsu Applicant before: SUZHOU COSMETIC MATERIALS Co.,Ltd. |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
CB03 | Change of inventor or designer information | ||
CB03 | Change of inventor or designer information |
Inventor after: Zhang Shaopeng Inventor before: Wu Zhenbiao |
|
TR01 | Transfer of patent right | ||
TR01 | Transfer of patent right |
Effective date of registration: 20170315 Address after: 102200 room A323, Zhongxing Road, Changping District science and Technology Park, Beijing, China, 10 Patentee after: BEIJING ZHONGKE TIEZHENJIU HEALTH TECHNOLOGY CO.,LTD. Address before: 362300 Fujian city of Quanzhou province Nanan kangmeikang beauty Development Zone Patentee before: NAN'AN YONGTENG TECHNOLOGY CONSULTATION Co.,Ltd. |
|
CF01 | Termination of patent right due to non-payment of annual fee | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20170208 Termination date: 20211110 |