CN104436038A - Compound preparation for treating hysteromyoma and preparation method thereof - Google Patents

Compound preparation for treating hysteromyoma and preparation method thereof Download PDF

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CN104436038A
CN104436038A CN201410659519.0A CN201410659519A CN104436038A CN 104436038 A CN104436038 A CN 104436038A CN 201410659519 A CN201410659519 A CN 201410659519A CN 104436038 A CN104436038 A CN 104436038A
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parts
preparation
compound preparation
hysteromyoma
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张登山
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/64—Insects, e.g. bees, wasps or fleas
    • A61K35/644—Beeswax; Propolis; Royal jelly; Honey
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/13—Coniferophyta (gymnosperms)
    • A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232—Angelica
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/324—Boswellia, e.g. frankincense
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A61K36/328—Commiphora, e.g. mecca myrrh or balm of Gilead
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10—Preparation or pretreatment of starting material
    • A61K2236/13—Preparation or pretreatment of starting material involving cleaning, e.g. washing or peeling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50—Methods involving additional extraction steps
    • A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

The invention discloses a compound preparation for treating hysteromyoma. The compound preparation is prepared from the following main raw materials in parts by weight: 5-15 parts of zedoary, 10-20 parts of propolis, 3-9 parts of maifanite, 4-9 parts of grape pip extract, 3-10 parts of pubescent angelica root, 15-30 parts of coptis root, 1-5 parts of ground beetles, 10-30 parts of frankincense, 10-20 parts of cinnamon, 5-9 parts of goldenlarch bark, 10-20 parts of myrrh and 12-16 parts of allium macrostemon. The compound preparation has a remarkable effect on hysteromyoma, has the effects of alleviating pain, sterilizing, diminishing inflammation and regulating endocrine secretion, and plays roles in promoting blood circulation to dispel blood stasis and clearing away heat and eliminating dampness. The compound preparation is prepared from locally-common medicinal materials mainly and is low in cost, and thus the economical burden of patients is lightened.

Description

A kind of compound preparation and method for making for the treatment of hysteromyoma
Technical field
The invention belongs to traditional Chinese medicine field, especially relate to a kind of compound preparation and method for making for the treatment of hysteromyoma.
Background technology
Hysteromyoma is modal a kind of benign tumor in female sex organ, is also one of modal tumor in human body, is also called fibromyoma, fibroma uteri.Because hysteromyoma is mainly formed by Uterine Smooth Cell hypertrophy, wherein there is a small amount of fibrous connective tissue to exist as a kind of supporting tissue, therefore be called that leiomyoma of uterus is comparatively definite.Be called for short hysteromyoma.
The cause of disease: about the cause of disease of hysteromyoma is still not fully aware of so far, may relate to the comparatively complicated interaction between the cell mutation of normal muscle layer, gonadal hormone and tropic growth factors.Show that hysteromyoma is a kind of hormone-dependent tumor according to a large amount of clinical observation and experimental result.Estrogen is the principal element impelling muscular tumor to grow, scholar is also had to think that growth hormone (GH) and muscular tumor grow also relevant, GH can work in coordination with estrogen mitosis promoting and promote that muscular tumor grows, and infer that human placental lactogen (HPL) also can work in coordination with estrogen mitogenesis effect, think Uterus during Pregnancy muscular tumor Acceleration of growth except outside the Pass having with trimester of pregnancy height hormonal milieu, possible HPL has also participated in effect.In addition ovarian function, hormone metabolism are all by the regulating and controlling of higher nervous center, therefore nerve centre activity also may play an important role to the morbidity of muscular tumor.Because hysteromyoma is more common in the inharmonic women of reproduction age, the death of one's spouse and sexual life.Chronicity life is lacked of proper care and causes pelvic cavity chronic congestion also may be one of reason of bringing out hysteromyoma.In a word, the generation development of hysteromyoma may be multifactor coefficient result.
Clinical manifestation: 1. symptom: most of patients is asymptomatic, is only occasionally found when pelvioscopy or ultrasonic examination.If any symptom then with muscular tumor growth site, speed, with or without degeneration and in close relations with or without complication, and relatively little with muscular tumor size, number how many relations.Suffer from multiple Subserous myoma person and may not have symptom, and under a less mucosa, muscular tumor often can cause irregular colporrhagia or menorrhagia.Symptom common clinically has: (1) metrorrhagia is the topmost symptom of hysteromyoma, comes across patient more than half.Be wherein many with cyclic hemorrhage, hyper-menorrhea, menostaxis or cycle time can be shown as.Also the irregular colporrhagia without menstrual cycle can be shown as.Metrorrhagia with muscular tumor under mucosa and intramural myoma more common, and Subserous myoma seldom causes metrorrhagia.(2) abdominal mass and pressure symptom muscular tumor grow gradually, when its make uterus increase above 3 months gravid uterus sizes or for being positioned at the larger Subserous myoma bottom palace time, often can lay one's hand on enclosed mass at abdominal part, more obvious during filling of bladder in early morning.Enclosed mass is solid, movable, without tenderness.Muscular tumor can cause peripheral organs pressure symptom when growing to a certain size, and anterior uterine wall muscular tumor presses close to bladder, and person can produce frequent micturition, urgent micturition; Huge cervical myoma compressing bladder can cause not smooth even urine retention of urinating; Uterus posterior myomas particularly isthmus or cervix uteri posterior lip muscular tumor can oppress rectum, causes that stool is smooth, sense of discomfort after defecation; Huge broad ligament myoma can oppress ureter, even causes hydronephrosis.(3) pain generally hysteromyoma do not cause pain, but many patients can tell the sense of lower abdomen falling inflation, aching pain in waist and back.Can acute abdominal pain be produced when Subserous myoma generation torsion of pedicle or hysteromyoma generation red degeneration, muscular tumor merge endometriosis or adenomyosis person also not rare, then can have dysmenorrhea.(4) leucorrhoea grow in quantity cavity of uterus increases, and endometrial gland increases, in addition pelvic congestion, and leucorrhea can be made to increase.Under the mucosa of uterus or cervix uteri when muscular tumor generation ulcer, infection, necrosis, then produce courageous and upright or purulent leukorrhea.(5) infertilely infertile or easy miscarriage is accompanied, on to become pregnant and the impact of pregnancy outcome may be relevant with the growth site of muscular tumor, size and number with some patients with uterine myoma of miscarriage.Giant left ventricle can cause uterine cavity to be out of shape, and hinders pregnant capsule implantation and embryo cutting; Muscular tumor compressing fallopian tube can cause tube chamber obstructed; Under mucosa, muscular tumor can hinder pregnant capsule implantation or affect sperm and enter uterine cavity.Hysteromyoma Patients rate of spontaneous abortion is higher than normal population, and it is than about 4: 1.(6) anemia can cause hemorrhagic anemia due to long-term menorrhagia or irregular colporrhagia, and more serious anemia is more common in Hysteromyoma Patients under mucosa.(7) other only a few patients with uterine myoma can produce erythrocytosis, hypoglycemia, it is generally acknowledged that to produce ectopic hormone with tumor relevant.
2. sign: (1) abdomen examination uterus increases above Subserous myoma bottom 3 months pregnant sizes or larger palace, can above pubic symphysis or hypogastric region center lay one's hand on and enclosed mass, solid, without tenderness, if the profile of multiple myomata then lump is irregular.(2) pelvioscopy gynecological bimanual examination, trimanual gynecologica examination, uterus is in increasing in various degree, and owe rule, there is irregular projection on surface, uterus, and in solid, if there is degeneration, quality is softer.During gynecologial examination, the sign of hysteromyoma is dissimilar and different according to it, if the pedunculated subserous myoma base of a fruit is longer, otherly in palace can to lay one's hand on and substantive enclosed mass, activity freely, this kind of situation easily and ovarian tumor obscure.Under mucosa, muscular tumor drops to cervix uteri mouth of pipe place, palace mouth pine, and examiner's finger stretches into the tumor body that can touch smooth, spherical in cervix uteri mouth, if emerged in cervix uteri mouth outward, can see tumor, and, in kermesinus, there is ulcer on surface sometimes, downright bad.Larger cervical myoma can make cervix uteri be shifted and distortion, cervix uteri can flattened or on move to pubic symphysis rear.
It is the medicament be made up by weight ratio of following traditional Chinese medicine raw that the patent document of Authorization Notice No. CN 103071007 A (application number 201110327277.1) discloses a kind of medicine for the treatment of hysteromyoma: Radix Scutellariae 5-15 gram, Radix Rehmanniae 10-20 gram, Rhizoma Coptidis 5-15 gram, Rhizoma Chuanxiong 3-10 gram, Radix Paeoniae Alba 5-15 gram, Olibanum 5-15 gram, Radix Rehmanniae Preparata 10-20 gram, Colla Corii Asini 10-20 gram, Herba Ecliptae 10-20 gram, Semen Cuscutae 10-20 gram, Os Sepiae 10-20 gram, Cacumen Platycladi 10-20 gram, Cortex Ailanthi 10-20 gram, Radix Rubiae 5-15 gram, Petiolus Trachycarpi 5-15 gram.The patent document of Authorization Notice No. CN 103550330 B (application number 201310560875.2) discloses a kind of Chinese drugs agentia for the treatment of hysteromyoma, it is characterized in that it is made up of following raw material medicaments: Herba Camptosori Sibirici 40-60 part, Herba Lactucae Indicae 20-40 part, chaetomers lagochilline 20-40 part, Radix Potentillae Fragarioidis 20-40 part, Rhizoma Polygoni Cuspidati 10-20 part, Olibanum 20-30 part, Myrrha 20-30 part, Radix et Rhizoma Dysosmatis 10-20 part, Caulis Fibraureae 10-20 part, Semen Momordicae 10-20 part, Semen Cuscutae 10-20 part, Radix Angelicae Dahuricae 10-15 part.
As can be seen here: Chinese medicine occupies very important status in treatment hysteromyoma, but in existing patent documentation, therapeutic effect is also bad, take how very large to the side effect of human body.
Summary of the invention
Along with the development of Chinese Chinese medicine, on Cure and control hysteromyoma, people gradually appreciate treatment by Chinese herbs hysteromyoma disease therapeutic process and have no side effect, patient bears painful little, and the advantage that cost is saved relatively, for the present situation of existing western medical treatment hysteromyoma, an object of the present invention is to provide a kind of compound preparation for the treatment of hysteromyoma, there is feature easy to operate, evident in efficacy, and it adopts Chinese crude drug comparatively common in the localities as raw material, with low cost.
Above-mentioned purpose of the present invention is achieved through the following technical solutions:
Treat a compound preparation for hysteromyoma, take off the primary raw material stating weight proportion and be prepared from: Rhizoma Curcumae 5-15 part, propolis 10-20 part, Maifanitum 3-9 part, Semen Vitis viniferae extract 4-9 part, Radix Angelicae Pubescentis 3-10 part, Rhizoma Coptidis 15-30 part, Eupolyphaga Seu Steleophaga 1-5 part, Olibanum 10-30 part, Cortex Cinnamomi 10-20 part, Cortex Pseudolaricis 5-9 part, Myrrha 10-20 part, Bulbus Allii Macrostemonis 12-16 part.
Treat a compound preparation for hysteromyoma, preferred scheme, take off the primary raw material stating weight proportion and be prepared from: Rhizoma Curcumae 8-13 part, propolis 13-18 part, Maifanitum 4-8 part, Semen Vitis viniferae extract 5-8 part, Radix Angelicae Pubescentis 4-8 part, Rhizoma Coptidis 18-28 part, Eupolyphaga Seu Steleophaga 2-4 part, Olibanum 13-25 part, Cortex Cinnamomi 14-18 part, Cortex Pseudolaricis 6-8 part, Myrrha 13-18 part, Bulbus Allii Macrostemonis 13-15 part.
Treat a compound preparation for hysteromyoma, best scheme, takes off the primary raw material stating weight proportion and is prepared from: Rhizoma Curcumae 10 parts, propolis 15 parts, Maifanitum 6 parts, Semen Vitis viniferae extract 7 parts, Radix Angelicae Pubescentis 5 parts, Rhizoma Coptidis 20 parts, Eupolyphaga Seu Steleophaga 3 parts, Olibanum 20 parts, Cortex Cinnamomi 15 parts, Cortex Pseudolaricis 7 parts, Myrrha 15 parts, Bulbus Allii Macrostemonis 14 parts.
Treat a preparation method for the compound preparation of hysteromyoma, be prepared from primarily of following step:
(1) Maifanitum is broken into the block of nail cover size, as in speciality container, in smokeless stove fire, forging is crisp, cools, and it is stand-by to grind to form smalls;
(2) Eupolyphaga Seu Steleophaga white vinegar is soaked 1-5 hour, take out, be placed in microwave oven, 80-90 DEG C, dry 1-5 minute, take out, it is stand-by to grind to form smalls;
(3) Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis are picked decontamination, clean, shredding, be placed in non iron container, add Chinese liquor, sealing and standing 10-20 hour, takes out, and is placed in and burns on hot iron plate, spread out even, little fire dries 20-30 minute slowly, cools, and becomes smalls stand-by with mortar grinder;
(4) by step (1)-(3) gained smalls mixing, as for the warm water adding 30-40 DEG C in marmite, intense fire is fried open, and boils 1-6 minute, turn 40-60 minute at a simmer, then put into continuous decoction of Semen Vitis viniferae extract slow fire to blow out to savory, put into propolis, again decoct 10-20 minute, to decoct after adding propolis while stir, leave standstill 50-100 minute, get supernatant, bottle and obtain compound preparation.
Above-mentioned preparation method, Eupolyphaga Seu Steleophaga white vinegar soaks 2-4 hour (preferred, Eupolyphaga Seu Steleophaga white vinegar is soaked 3 hours) by step (2).
Above-mentioned preparation method, step (2) is placed in microwave oven, 83-88 DEG C, dries 2-4 minute (preferred, to be placed in microwave oven, 85 DEG C, to dry 3 minutes).
Above-mentioned preparation method, the consumption of step (3) Chinese liquor be Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis gross weight 1-5 doubly (preferred, the consumption of Chinese liquor be Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis gross weight 2-4 doubly, be more preferably, the consumption of Chinese liquor be Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis gross weight 3 times).
Above-mentioned preparation method, the number of degrees of step (3) Chinese liquor are 40-55 degree (preferred, the number of degrees of Chinese liquor are 48-52 degree, are more preferably, and the number of degrees of Chinese liquor are 50 degree).
Above-mentioned preparation method, step (4) is as the warm water adding 33-38 DEG C in marmite, and intense fire is fried open, boil 2-5 minute, turn 45-55 at a simmer minute (preferred, as the warm water adding 35 DEG C in marmite, intense fire is fried open, and boils 4 minutes, turns 50 minutes at a simmer).
Above-mentioned preparation method, step (4) leaves standstill 60-90 minute, gets supernatant (preferred, to leave standstill 75 minutes, get supernatant).
This compound preparation, to hysteromyoma Be very effective, not only has effect of pain relieving, sterilization, antiinflammatory, endocrine regulation, also has the effect of blood circulation promoting and blood stasis dispelling, clearing away heat and eliminating dampness.The local common medical material of multiselect of the present invention, cheap, alleviate the financial burden of patient.
The pharmacological effect of each crude drug is respectively:
Rhizoma Curcumae: Rhizoma Curcumae, other Cheng Shu medicine, Curcuma Shu, blue or green Rhizoma Zingiberis Recens, evil mind Rhizoma Zingiberis Recens, Rhizoma Curcumae Longae, (1) removing blood stasis circulation of qi promoting, removing food stagnancy pain relieving.For abdominal pain due to blood stasis, hepatosplenomegaly, trusted subordinate's distending pain, gather, women's blood stasis amenorrhea, traumatic injury is had a pain eating accumulation.(2) promoting the circulation of QI to relieve pain, removing blood stasis removing food stagnancy: for the amenorrhea of qi depression to blood stasis, chest and hypochondrium, stomachache and lump in the abdomen lump etc.
Maifanitum: base is former: be Acid-intermediate igneous rock rocks beschtauite.Composition: Maifanitum main component has silicon dioxide, aluminium oxide, ferrum oxide, ferrous oxide, magnesium oxide, calcium oxide, sodium oxide, potassium oxide, titanium dioxide, phosphorus pentoxide, manganese oxide, carbon dioxide, and the trace element such as fluorine, sulfur, strontium, barium, copper, zinc.The property of medicine: " detailed outline ": " sweet, temperature, nontoxic." function cures mainly: removing toxic substances and promoting granulation, damp eliminating spleen invigorating.Cure mainly carbuncle carbuncle on the back, acne, eczema, beriberi, miliaria, finger is chapped, chloasma, toothache, oral ulcer, rheumatic arthralgia, lumbago and backache, chronic hepatitis, gastritis, dysentery, diabetes, neurasthenia, wound is red and swollen, hypertension, senile sclerosis of blood vessels, tumor, lithangiuria.Generally make health product.Compatibility and incompatibility of drugs: superfine end need be ground during external application, otherwise easily cause pain.
Semen Vitis viniferae extract: Semen Vitis viniferae extract is the nutraceutical that the effective active nutrition extracted from natural grape seed is equipped with the primary raw materials such as vitamin E and refines.Semen Vitis viniferae extract is the new and effective Natural antioxidant material that can not synthesize in a kind of human body of extracting from Semen Vitis viniferae.It is the antioxidation that current occurring in nature finds, the material that Scavenging ability is the strongest, its antioxidant activity is 50 times, ascorbic 20 times of the plain E of dimension, it can effectively remove free radical unnecessary in human body, has superpower slow down aging and the effect of enhancing immunity.Antioxidation, antiallergic, resisting fatigue health invigorating, improve sub-health state slow down aging, improve irritable, the symptom such as dizzy weak, hypomnesis.1. Semen Vitis viniferae extract main active is the low-molecular-weight of procyanidin, and it is a kind of antioxidant of brute force, a kind of effective free radical scavenger; 2. are natural sunlight overcovers, skin can be encroached on by shielding of ultraviolet; 3. procyanidin can repair injured collagen protein and elastic fiber, has astriction, tightens up skin, and prevent wrinkle of skin from occurring ahead of time, life-time service can make skin smooth, high resilience, has the effect of looks improving and the skin nourishing; 4, the initiation potential of the symptoms such as heart disease, cancer, senilism, arthritis, hypertension, senile dementia, degenerative eye speckle and cataract can be reduced.
Propolis: antibacterial action.The sterilizing of propolis energy, sterilization, sterilization, antibacterial, mildew-resistant, anticorrosion, solve the defect that antibiotic only works to single microorganism, and be free from side effects.Good therapeutic effect is had in daily life to dermatosis.Antivirus action.Propolis is natural antiviral substance, has very strong suppression and killing action to multiple virus.Antioxidation.Propolis is called as antioxidant and free radical scavenger, effectively can remove the refuses such as excess activated oxygen because the bad life habits such as fat, overworked, environmental pollution, smoking and extraneous factor produce and free radical.Enhancing immunity effect.The immune system of human body is easily infracting by virus, and propolis can strengthen body immunity, strengthens the ability of human body opposing virus infraction.Antitumaous effect.Both at home and abroad large quantifier elimination shows, propolis has good effect pressing down cancer anticancer aspect.Promote cell regeneration effect.Propolis can accelerate the healing of tissue regeneration and wound.Effects of beautification and nourishing face.Propolis can decompose pigment, calm down wrinkle, delaying senility etc., is women's cosmetic good merchantable brand.Analgesic activity.Propolis also has good effect in analgesia.Prophylaxis of tumours.Containing abundant cancer-resisting substance in propolis, research proves, cancer patient after taking propolis, can cancerous cell be reduced and chemotherapy can be alleviated, side effect that radiotherapy causes.Resisting hypertension.Suffering from hypertensive patient takes containing very many Flavonoid substances and the propolis with very strong anti-oxidation ability continuously, not only can reduce over the harm of lipid oxide to blood vessel, prevent sclerosis of blood vessels, and effectively can also reduce the content of triglyceride, reduce platelet aggregation, improve microcirculation, too high blood pressure can be reduced, prevent the generation of unexpected thing.Thus, middle-aged and elderly people, particularly hypertension, heart disease, arteriosclerosis patient, usually take propolis, quite has benifit to good health and a long life.
Radix Angelicae Pubescentis: be the root of the heavy tooth Radix Angelicae Sinensis of Umbelliferae archangel.Composition: containing coumarin kind compound, volatile oil, acetas, angelol, thymol.Pharmacology: play a very important role to cardiovascular system, has the effect of blood pressure lowering, can promote hematoblastic gathering, have good analgesia and antiinflammatory action.There is anti-light quick effect, have significant curative effect to opposing tumor, anti-inflammation is also played a very important role.The property of medicine: bitter, tepor, pungent.Return kidney, urinary bladder channel.Function cures mainly: expelling wind and dampness, dispersing cold for relieving pain.
Rhizoma Coptidis: Rhizoma Coptidis, another name: taste company, Rhizoma Coptidis, Rhizoma Coptidis, belongs to Ranunculaceae, Coptis herbaceos perennial, heat clearing and damp drying, eliminating fire and detoxication.For damp and hot feeling of fullness, vomiting acid regurgitation, dysentery, jaundice, unconsciousness due to high fever, hyperactivity of heart-fire, dysphoria and insomnia, heat in blood tells nosebleed, conjunctival congestion, and toothache, quenches one's thirst, carbuncle furuncle; External treatment eczema, eczema, auditory meatus is suppurated.It is burning hot that Rhizoma Coptidis (processed with wine) is apt to the clear part of the body cavity above the diaphragm housing the heart and lungs.For conjunctival congestion, aphtha.Prepared RHIZOMA COPTIDIS with rhizoma zingiberis recens juice clearing stomach stomach function regulating preventing or arresting vomiting.Tie mutually for cold and heat, damp and hot middle resistance, feeling of fullness is vomitted.Cornel Rhizoma Coptidis soothing liver-QI stomach function regulating preventing or arresting vomiting.For incoordination between the liver and stomach, vomiting acid regurgitation.
Eupolyphaga Seu Steleophaga: nature and flavor: salty, cold; Slightly poisonous.Gui Jing: return Liver Channel.Effect: removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.Cure mainly: for injured bone, blood stasis amenorrhea ， mass in the abdomen mass in the abdomen.
Olibanum: Olibanum, real name smokes land, and the smoked Lu Xiang of another name, horse hair is fragrant, nipple is fragrant, the perfume (or spice) that collapses, sky pool is fragrant, Moller is fragrant, many gals Luo Xiang etc., and regulating qi and activating blood, analgesic therapy, chases after poison.Control coagulation of QI-blood, trusted subordinate's pain, carbuncle pyogenic infections from tumour or sore, traumatic injury, dysmenorrhea, postnatal blood stasis twinge.
Cortex Cinnamomi: base is former: be dried bark, the branch skin of Lauraceae cinnamon Cortex Cinnamomi.Composition: Cortex cinnamomi japonici (Ramulus Cinnamomi) is containing volatile oil 1.89%-2.06%, and its main component is cinnamic aldehyde, accounts for 52.92%-61.20%, also has acetic acid Cortex cinnamomi japonici (Ramulus Cinnamomi) ester, ethyl cinnamate, benzaldehyde benzyl ester, benzaldehyde, coumarin etc.The property of medicine: pungent, sweet, heat.Return kidney, spleen, the heart, Liver Channel.Function cures mainly: mend fire supporing yang, dispersing cold for relieving pain, warming the meridian and promoting blood circulation.Cure mainly insufficiency of kidney-YANG, the aversion to cold and cold limbs of decline of the fire from the gate of life, soreness of the waist and knees, impotence and seminal emission, dysuria or frequency, dyspnea with rapid and short breath of losing heart, all diseases of edema oliguria; Decline of the fire from the gate of life, fire is Gui Yuan not, floating YANG, refusing yang, and heat in the upper and cold in the lower, flushed complexion cold foot, dizziness and tinnitus, and dispute gruel is broken; Spleen-kidney vacuity cold, coldness and pain in the epigastrium, decreased food intake loose stool; Lumbago due to renal deficiency; Arthralgia due to cold-dampnes; Colic of cold type pain, cold womb is infertile, dysmenorrhea amenorrhea, stomachache of being retarded by silt puerperal; Carbuncle of yin nature multiple abscess, or deficiency and coldness carbuncle and ulcer difficulty in discharging of pus, or do not hold back after bursting.
Cortex Pseudolaricis: have another name called arhat Cortex Pini Massonianae, wattle skin, pseudolaricis,cortex is root bark and the near root bark of Pinaceae Pseudolarix plant golden larch.The property of medicine: root bark is irregular strip, distortion and slightly rolling up, not of uniform size, matter is tough, feeble QI, acrid in the mouth, hardship, warm in nature.Composition: root bark contains pseudolaric acid B, betulic acid, myricetin, amaron alcohol A and B etc.Find according to modern pharmacological research, this medical instrument has effect of antifungal, anticancer, expelling wind and removing dampness, killing parasites for relieving itching, for eczema, and neurodermatitis.
Myrrha: cure mainly breast abdomen stasis of blood pain, dysmenorrhea, amenorrhea, lump in the abdomen, traumatic injury, carbuncle skin infection, acute appendicitis, conjunctival congestion and swelling pain.There is the effect such as promoting blood circulation and stopping pain, detumescence and promoting granulation.
Bulbus Allii Macrostemonis: Bulbus Allii Macrostemonis, another name Allium macrostemon, Bullbus Allii nipponici, bitter Bulbus Allii, little Bulbus Allii, little root vegetables, little root vegetables, large head, wild Bulbus Allii, Herba Allii prattii, wild Taipa.Pungent, bitter, temperature.GUIXIN, lung, stomach, large intestine channel.Activating YANG and eliminating stagnation, circulation of qi promoting intestinal stasis relieving.For obstruction of qi in the chest and cardialgia, gastral cavity abdomen feeling of fullness distending pain, heavy after dysentery.
Compound preparation of the present invention debates the principle of disease treatment based on Chinese medicine, and treatment is more comprehensive, and affected area administration is more rapid, and lasting medicine, the hysteromyoma prescription for the treatment of both the principal and secondary aspects of a disease, has fabulous therapeutical effect to hysteromyoma.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not by this restriction.
Embodiment 1 one kinds treats the compound preparation of hysteromyoma, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Curcumae 5 parts, propolis 10 parts, Maifanitum 3 parts, Semen Vitis viniferae extract 4 parts, Radix Angelicae Pubescentis 3 parts, Rhizoma Coptidis 15 parts, Eupolyphaga Seu Steleophaga 1 part, Olibanum 10 parts, Cortex Cinnamomi 10 parts, Cortex Pseudolaricis 5 parts, Myrrha 10 parts, Bulbus Allii Macrostemonis 12 parts.
The preparation method of the compound preparation of above-mentioned treatment hysteromyoma, step is as follows:
(1) Maifanitum is broken into the block of nail cover size, as in speciality container, in smokeless stove fire, forging is crisp, cools, and it is stand-by to grind to form smalls;
(2) Eupolyphaga Seu Steleophaga white vinegar is soaked 1 hour, take out, be placed in microwave oven, 80 DEG C, dry 1 minute, taking-up, it is stand-by to grind to form smalls;
(3) Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis are picked decontamination, clean, shredding, be placed in non iron container, add the Chinese liquor of 40 degree, the consumption of Chinese liquor be Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis gross weight 1 times, sealing and standing 10 hours, take out, be placed in and burn on hot iron plate, spread out even, little fire dries 20 minutes slowly, cool, become smalls stand-by with mortar grinder;
(4) by step (1)-(3) gained smalls mixing, as for the warm water adding 30 DEG C in marmite, intense fire is fried open, and boils 1 minute, turn 40 minutes at a simmer, then put into continuous decoction of Semen Vitis viniferae extract slow fire to blow out to savory, put into propolis, again decoct 10 minutes, to decoct after adding propolis while stir, leave standstill 50 minutes, get supernatant, bottle and obtain compound preparation.
Model case one: Song XX, female, 45 years old, people from Jiyang, Shandong Province.Patient is the multiple muscular tumor in ultrasound diagnosis discovery uterus before 3 years.After ultrasonic interventional therapy, in uneven strong echo in antetheca muscular tumor essence, border is comparatively clear, has no blood flow signal in essence; In opaque dark area of fluid (opaque dark area of fluid represents liquefaction and necrosis) in posterior myomas essence.1, the multiple muscular tumor in uterus, antetheca muscular tumor 39x37mm at the bottom of former palace, posterior myomas 33x31mm, 2, CDFI shows visible abundant blood flow signal in antetheca muscular tumor, 3, PW:VS318.6mm/s, RI0.64mm.After comprehensively checking, doctor advised takes gained compound preparation of the present invention.
Take embodiment 1 gained compound preparation and combined with chemotherapy treats 10 days, self-induction symptom alleviates; Use compound preparation of the present invention to treat 15 days, antetheca muscular tumor is reduced into 34x33mm to go examination in hospital to find, in the strong echo of inequality in antetheca muscular tumor essence, border is comparatively clear, the visible strong echo ring of light of periphery; Continue medication 1 month, complexion is than originally there being very large change, and through hospital's check, stable disease, posterior myomas is reduced into 24x22mm, and in opaque dark area of fluid in posterior myomas essence, rule is owed on (opaque dark area of fluid represents liquefaction and necrosis) border, and self-induction is fully recovered.
Embodiment 2 one kinds treats the compound preparation of hysteromyoma, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Curcumae 15 parts, propolis 20 parts, Maifanitum 9 parts, Semen Vitis viniferae extract 9 parts, Radix Angelicae Pubescentis 10 parts, Rhizoma Coptidis 30 parts, Eupolyphaga Seu Steleophaga 5 parts, Olibanum 30 parts, Cortex Cinnamomi 20 parts, Cortex Pseudolaricis 9 parts, Myrrha 20 parts, Bulbus Allii Macrostemonis 16 parts.
The preparation method of the compound preparation of above-mentioned treatment hysteromyoma, step is as follows:
(1) Maifanitum is broken into the block of nail cover size, as in speciality container, in smokeless stove fire, forging is crisp, cools, and it is stand-by to grind to form smalls;
(2) Eupolyphaga Seu Steleophaga white vinegar is soaked 1-5 hour, take out, be placed in microwave oven, 90 DEG C, dry 5 minutes, taking-up, it is stand-by to grind to form smalls;
(3) Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis are picked decontamination, clean, shredding, be placed in non iron container, add the Chinese liquor of 55 degree, the consumption of Chinese liquor be Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis gross weight 5 times, sealing and standing 20 hours, take out, be placed in and burn on hot iron plate, spread out even, little fire dries 30 minutes slowly, cool, become smalls stand-by with mortar grinder;
(4) by step (1)-(3) gained smalls mixing, as for the warm water adding 40 DEG C in marmite, intense fire is fried open, and boils 6 minutes, turn 60 minutes at a simmer, then put into continuous decoction of Semen Vitis viniferae extract slow fire to blow out to savory, put into propolis, again decoct 20 minutes, to decoct after adding propolis while stir, leave standstill 100 minutes, get supernatant, bottle and obtain compound preparation.
Embodiment 3 one kinds treats the compound preparation of hysteromyoma, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Curcumae 8 parts, propolis 13 parts, Maifanitum 4 parts, Semen Vitis viniferae extract 5 parts, Radix Angelicae Pubescentis 4 parts, Rhizoma Coptidis 18 parts, Eupolyphaga Seu Steleophaga 2 parts, Olibanum 13 parts, Cortex Cinnamomi 14 parts, Cortex Pseudolaricis 6 parts, Myrrha 13 parts, Bulbus Allii Macrostemonis 13 parts.
The preparation method of the compound preparation of above-mentioned treatment hysteromyoma, step is as follows:
(1) Maifanitum is broken into the block of nail cover size, as in speciality container, in smokeless stove fire, forging is crisp, cools, and it is stand-by to grind to form smalls;
(2) Eupolyphaga Seu Steleophaga white vinegar is soaked 2 hours, take out, be placed in microwave oven, 83 DEG C, dry 2 minutes, taking-up, it is stand-by to grind to form smalls;
(3) Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis are picked decontamination, clean, shredding, be placed in non iron container, add the Chinese liquor of 48 degree, the consumption of Chinese liquor be Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis gross weight 2 times, sealing and standing 13 hours, take out, be placed in and burn on hot iron plate, spread out even, little fire dries 23 minutes slowly, cool, become smalls stand-by with mortar grinder;
(4) by step (1)-(3) gained smalls mixing, as for the warm water adding 33 DEG C in marmite, intense fire is fried open, and boils 2 minutes, turn 45 minutes at a simmer, then put into continuous decoction of Semen Vitis viniferae extract slow fire to blow out to savory, put into propolis, again decoct 13 minutes, to decoct after adding propolis while stir, leave standstill 60 minutes, get supernatant, bottle and obtain compound preparation.
Embodiment 4 one kinds treats the compound preparation of hysteromyoma, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Curcumae 13 parts, propolis 18 parts, Maifanitum 8 parts, Semen Vitis viniferae extract 8 parts, Radix Angelicae Pubescentis 8 parts, Rhizoma Coptidis 28 parts, Eupolyphaga Seu Steleophaga 4 parts, Olibanum 25 parts, Cortex Cinnamomi 18 parts, Cortex Pseudolaricis 8 parts, Myrrha 18 parts, Bulbus Allii Macrostemonis 15 parts.
The preparation method of the compound preparation of above-mentioned treatment hysteromyoma, step is as follows:
(1) Maifanitum is broken into the block of nail cover size, as in speciality container, in smokeless stove fire, forging is crisp, cools, and it is stand-by to grind to form smalls;
(2) Eupolyphaga Seu Steleophaga white vinegar is soaked 4 hours, take out, be placed in microwave oven, 88 DEG C, dry 4 minutes, taking-up, it is stand-by to grind to form smalls;
(3) Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis are picked decontamination, clean, shredding, be placed in non iron container, add the Chinese liquor of 52 degree, the consumption of Chinese liquor be Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis gross weight 4 times, sealing and standing 18 hours, take out, be placed in and burn on hot iron plate, spread out even, little fire dries 28 minutes slowly, cool, become smalls stand-by with mortar grinder;
(4) by step (1)-(3) gained smalls mixing, as for the warm water adding 38 DEG C in marmite, intense fire is fried open, and boils 5 minutes, turn 55 minutes at a simmer, then put into continuous decoction of Semen Vitis viniferae extract slow fire to blow out to savory, put into propolis, again decoct 18 minutes, to decoct after adding propolis while stir, leave standstill 90 minutes, get supernatant, bottle and obtain compound preparation.
Model case two: Zhu xx, female, 44 years old, people from Jinan City, Shandong Province.Make a living to sell vegetable, lumbago companion stomachache more than ten sky.Private prosecution May menstruation rear ten days only, answers colporrhagia more than ten sky again, and amount is few, color is dark red, accompanies slight lumbosacral region and middle lower abdominal pain 12 days Mays 20 to two in my clinic transfusion (medication clindamycin, etamsylate) after three days, through clean, but lumbago and hypogastralgia do not subtract, and over nearest more than ten skies, lumbago and lower abdominal pain increase the weight of, pain is persistence dull pain, tired postemphasis, without paroxysmal aggravation, leucorrhea amount is few, slightly yellow, free from extraneous odour.The heat that do not occur together shiver with cold, nausea and vomiting, other discomfort such as extremity limitation of activity.Spirit since patient's onset, appetite, defecation is normal.Tentative diagnosis through doctor is diagnosed as hysteromyoma, doctor advised its take gained compound preparation of the present invention.
Take embodiment 4 gained compound preparation and treat 5 days, pain symptom alleviates; Use compound preparation of the present invention to treat 1 month, pain disappears, and leucorrhea is normal, and menstrual blood volume also recovers normal; Use compound preparation of the present invention to treat 10 days, the state of an illness is basicly stable, and self-induction is fully recovered.
Embodiment 5 one kinds treats the compound preparation of hysteromyoma, takes off the primary raw material stating weight proportion and is prepared from (getting 10g for every part): Rhizoma Curcumae 10 parts, propolis 15 parts, Maifanitum 6 parts, Semen Vitis viniferae extract 7 parts, Radix Angelicae Pubescentis 5 parts, Rhizoma Coptidis 20 parts, Eupolyphaga Seu Steleophaga 3 parts, Olibanum 20 parts, Cortex Cinnamomi 15 parts, Cortex Pseudolaricis 7 parts, Myrrha 15 parts, Bulbus Allii Macrostemonis 14 parts.
The preparation method of the compound preparation of above-mentioned treatment hysteromyoma, step is as follows:
(1) Maifanitum is broken into the block of nail cover size, as in speciality container, in smokeless stove fire, forging is crisp, cools, and it is stand-by to grind to form smalls;
(2) Eupolyphaga Seu Steleophaga white vinegar is soaked 3 hours, take out, be placed in microwave oven, 85 DEG C, dry 3 minutes, taking-up, it is stand-by to grind to form smalls;
(3) Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis are picked decontamination, clean, shredding, be placed in non iron container, add the Chinese liquor of 50 degree, the consumption of Chinese liquor be Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis gross weight 3 times, sealing and standing 15 hours, take out, be placed in and burn on hot iron plate, spread out even, little fire dries 25 minutes slowly, cool, become smalls stand-by with mortar grinder;
(4) by step (1)-(3) gained smalls mixing, as for the warm water adding 35 DEG C in marmite, intense fire is fried open, and boils 4 minutes, turn 50 minutes at a simmer, then put into continuous decoction of Semen Vitis viniferae extract slow fire to blow out to savory, put into propolis, again decoct 15 minutes, to decoct after adding propolis while stir, leave standstill 75 minutes, get supernatant, bottle and obtain compound preparation.
Experimental example: in order to verify the effect of compound preparation of the present invention, from in January, 2011 in January, 2014 in 10 hospitals, have chosen the experiment (embodiment 5) that 400 patients with uterin leiomyoma patients have carried out medicine, be divided into matched group and experimental group, matched group 200 people, experimental group 200 people, matched group takes the Western medicine of other treatment hysteromyoma (as Xiaojin Capsules, puerperal blood clot dispersing tablet, GUIZHI FULING JIAONANG, the medicine of the conventional therapy hysteromyoma such as PINGXIAO PIAN), experimental group takes gained compound preparation of the present invention, instructions of taking: be the therapeutic effect making the present invention reach best, get the compound preparation 5-10m1 prepared at every turn, warm water delivery service, sugaring that can be suitable according to individual taste, in sooner or later taking half an hour after meal, it within 10 days, is a course for the treatment of.Criterion: cure: after taking medicine, malaise symptoms disappears, menstruation recovery is normal, does not have the phenomenon of suffering from abdominal pain, and effectively: after taking medicine, malaise symptoms improves, menstruation recovers normal substantially, does not have the phenomenon of suffering from abdominal pain, invalid: malaise symptoms is unchanged.Accurately statistics and mathematical analysis are carried out to data.
Specific experiment result is as following table:
Table 1:
During taking, patient's self-induction symptom is as shown in table 2:
Table 2:
Prove through clinical trial, use compound preparation of the present invention compared with the means of western medical treatment hysteromyoma, control recurrence rate after healing low, treatment means is more comprehensive thoroughly, have no side effect between the operating period, while treatment hysteromyoma, the symptom such as pain, inappetence, menoxenia brought by hysteromyoma can be alleviated.Prove through clinical trial, Chinese drugs agentia effective percentage of the present invention is 98%, all has good therapeutical effect for hysteromyoma in early stage and late period, and most of patients with uterine myoma was medication about 2 days, and pain symptom has and obviously alleviates.For early stage patients with uterine myoma, adhere to using compound preparation of the present invention, be substantially inhibited about 1 month disease, therefore compound preparation of the present invention is a kind of medicine for the treatment of hysteromyoma safely and effectively.

Claims (10)

1. treat a compound preparation for hysteromyoma, it is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Rhizoma Curcumae 5-15 part, propolis 10-20 part, Maifanitum 3-9 part, Semen Vitis viniferae extract 4-9 part, Radix Angelicae Pubescentis 3-10 part, Rhizoma Coptidis 15-30 part, Eupolyphaga Seu Steleophaga 1-5 part, Olibanum 10-30 part, Cortex Cinnamomi 10-20 part, Cortex Pseudolaricis 5-9 part, Myrrha 10-20 part, Bulbus Allii Macrostemonis 12-16 part.
2. the compound preparation for the treatment of hysteromyoma according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Rhizoma Curcumae 8-13 part, propolis 13-18 part, Maifanitum 4-8 part, Semen Vitis viniferae extract 5-8 part, Radix Angelicae Pubescentis 4-8 part, Rhizoma Coptidis 18-28 part, Eupolyphaga Seu Steleophaga 2-4 part, Olibanum 13-25 part, Cortex Cinnamomi 14-18 part, Cortex Pseudolaricis 6-8 part, Myrrha 13-18 part, Bulbus Allii Macrostemonis 13-15 part.
3. the compound preparation for the treatment of hysteromyoma according to claim 1, is characterized in that: take off the primary raw material stating weight proportion and be prepared from: Rhizoma Curcumae 10 parts, propolis 15 parts, Maifanitum 6 parts, Semen Vitis viniferae extract 7 parts, Radix Angelicae Pubescentis 5 parts, Rhizoma Coptidis 20 parts, Eupolyphaga Seu Steleophaga 3 parts, Olibanum 20 parts, Cortex Cinnamomi 15 parts, Cortex Pseudolaricis 7 parts, Myrrha 15 parts, Bulbus Allii Macrostemonis 14 parts.
4. the preparation method of the compound preparation of the treatment hysteromyoma according to any one of claim 1-3, is characterized in that: step is as follows:
(1) Maifanitum is broken into the block of nail cover size, as in speciality container, in smokeless stove fire, forging is crisp, cools, and it is stand-by to grind to form smalls;
(2) Eupolyphaga Seu Steleophaga white vinegar is soaked 1-5 hour, take out, be placed in microwave oven, 80-90 DEG C, dry 1-5 minute, take out, it is stand-by to grind to form smalls;
(3) Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis are picked decontamination, clean, shredding, be placed in non iron container, add Chinese liquor, sealing and standing 10-20 hour, takes out, and is placed in and burns on hot iron plate, spread out even, little fire dries 20-30 minute slowly, cools, and becomes smalls stand-by with mortar grinder;
(4) by step (1)-(3) gained smalls mixing, as for the warm water adding 30-40 DEG C in marmite, intense fire is fried open, and boils 1-6 minute, turn 40-60 minute at a simmer, then put into continuous decoction of Semen Vitis viniferae extract slow fire to blow out to savory, put into propolis, again decoct 10-20 minute, to decoct after adding propolis while stir, leave standstill 50-100 minute, get supernatant, bottle and obtain compound preparation.
5. preparation method according to claim 4, is characterized in that: Eupolyphaga Seu Steleophaga white vinegar soaks 2-4 hour (preferred, Eupolyphaga Seu Steleophaga white vinegar is soaked 3 hours) by step (2).
6. preparation method according to claim 4, is characterized in that: step (2) is placed in microwave oven, 83-88 DEG C, dries 2-4 minute (preferred, to be placed in microwave oven, 85 DEG C, to dry 3 minutes).
7. preparation method according to claim 4, it is characterized in that: the consumption of step (3) Chinese liquor be Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis gross weight 1-5 doubly (preferred, the consumption of Chinese liquor be Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis gross weight 2-4 doubly, be more preferably, the consumption of Chinese liquor be Rhizoma Curcumae, Radix Angelicae Pubescentis, Rhizoma Coptidis, Olibanum, Cortex Cinnamomi, Cortex Pseudolaricis, Myrrha and Bulbus Allii Macrostemonis gross weight 3 times).
8. preparation method according to claim 4, is characterized in that: the number of degrees of step (3) Chinese liquor are 40-55 degree (preferred, the number of degrees of Chinese liquor are 48-52 degree, are more preferably, and the number of degrees of Chinese liquor are 50 degree).
9. preparation method according to claim 4, it is characterized in that: step (4) is as the warm water adding 33-38 DEG C in marmite, intense fire is fried open, boil 2-5 minute, (preferred, as the warm water adding 35 DEG C in marmite, intense fire is fried open to turn 45-55 at a simmer minute, boil 4 minutes, turn 50 minutes at a simmer).
10. preparation method according to claim 4, is characterized in that: step (4) leaves standstill 60-90 minute, gets supernatant (preferred, to leave standstill 75 minutes, get supernatant).
CN201410659519.0A 2014-11-18 2014-11-18 Compound preparation for treating hysteromyoma and preparation method thereof Pending CN104436038A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090031297A (en) * 2007-09-20 2009-03-25 김상수 Method for making pills for obsteric symptoms
CN102302659A (en) * 2011-06-28 2012-01-04 上海泰坤堂中医医院 Chinese medicinal composition for kidney-yang deficiency and phlegm-retention type polycystic ovanian syndrome

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20090031297A (en) * 2007-09-20 2009-03-25 김상수 Method for making pills for obsteric symptoms
CN102302659A (en) * 2011-06-28 2012-01-04 上海泰坤堂中医医院 Chinese medicinal composition for kidney-yang deficiency and phlegm-retention type polycystic ovanian syndrome

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
周秋丽等: "《现代中药基础研究与临床》", 30 June 2012, 天津科技翻译出版公司 *
安徽省食品药品监督管理局: "《安徽省中药饮片炮制规范：2005年版》", 31 October 2006, 安徽科学技术出版社 *
李宇燕: "中药内服外渗法治疗子宫肌瘤98例", 《湖北中医杂志》 *
梁惠风: "《《黄帝内经》和《本草纲目》中的女人养生药膳速查全书》", 31 December 2013, 金盾出版社 *
高彦祥: "《食品添加剂》", 31 May 2011, 中国轻工业出版社 *

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Application publication date: 20150325