CN104435844A - Asthma construction clearing and detoxifying pharmaceutical preparation and preparation method - Google Patents
Asthma construction clearing and detoxifying pharmaceutical preparation and preparation method Download PDFInfo
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Abstract
The invention discloses an asthma construction clearing and detoxifying pharmaceutical preparation, which is mainly prepared from the following active pharmaceutical ingredients in parts by weight: 6-9 parts of light wheat, 5-10 parts of codonopsis pilosula, 5-9 parts of henbane leaf, 9-15 parts of caulis bambusae, 6-9 parts of scorch-fried white atractylodes, 4-8 parts of terminalia chebula retz, 6-12 parts of almonds, 3-6 parts of alkali, 3-6 parts of agilawood, 8-12 parts of centella and 3-6 parts of scorpion. The preparation is obvious in efficacy, safe to take and free from side effects.
Description
Technical field
The present invention relates to traditional Chinese medicine field, particularly relate to a kind of asthma clearing heat in YING system antidote preparation and preparation method.
Background technology
Asthma is a kind of multiple commonly encountered diseases, its cardinal symptom be paroxysmally to pant, the symptom such as out of breath, uncomfortable in chest or cough, small number of patients may take also chest pain as main manifestations, these symptoms are shown effect after contacting the irritative gass such as smog, perfume, paint, dust, house pet, pollen or allergen through the patient that is everlasting, night and (or) also easily generation or the aggravation of symptom in early morning.A lot of patient is oneself audible and sound of stridulating when asthma attack.Symptom is normally paroxysmal, most of patients can spontaneous remission or through treatment alleviate.If asthmatic patient occurs that serious acute shows effect, may be fatal when giving treatment to not in time.Control not good asthmatic patient all can make a difference to routine work and daily life, can cause delaying work, learn by mistake, cause activity, limitation of movement, quality of life is declined, and bring burden economically and the life generation negative effect to household.The drug main of western medical treatment asthma will be divided into control medicine and cushion, wherein control medicine and refer to the medicine needing use long-term every day, asthma is made to maintain clinic control mainly through antiinflammatory action, comprising inhaled (abbreviation hormone) whole body hormone, leukotrienes regulator, long acting β_2 agonistics (long-acting Β 2-receptor stimulating agent, must with powder for inhalation use in conjunction), sustained-release theophyline, anti-IgE antibodies and other contribute to the medicine etc. reducing systemic hormone dosage; Cushion refers to the medicine used as required, by removing bronchospasm rapidly thus relieving asthma symptoms, comprising quick-acting suction broxaterol, whole body hormone, imbedibility anticholinergic agents, fugitive theophylline and fugitive oral broxaterol etc.
Publication No. CN 102716290 A(application number 201210231814.7) Chinese patent literature disclose a kind of Chinese medicine for the treatment of bronchial asthma, the ingredient comprising following parts by weight is prepared from: the Rhizoma Cynanchi Stauntonii of the Pericarpium Citri Reticulatae of the Herba Ephedrae of 5 ~ 15 parts by weight, the Semen Armeniacae Amarum of 5 ~ 15 parts by weight, 10 ~ 20 parts by weight, the Rhizoma Pinelliae of 5 ~ 15 parts by weight, 10 ~ 20 parts by weight, the Radix Peucedani of 10 ~ 20 parts by weight, the Folium Eriobotryae of 10 ~ 20 parts by weight, the Radix Glycyrrhizae of 5 ~ 10 parts by weight, the present invention has effect of depressed lung-energy dispersing, expelling phlegm for arresting cough.Publication No. CN 102145144 A(application number 201110084709.0) Chinese patent literature disclose a kind of Chinese medicine preparation for the treatment of asthma, be made up of following raw material of Chinese medicine, Semen Lepidii (Semen Descurainiae), Rhizoma Belamcandae, Radix Scutellariae, Concha Meretricis seu Cyclinae, the Radix Stemonae, Fructus Chebulae, Cortex Mori, Radix Peucedani, Flos Farfarae, Flos Inulae, Ramulus Uncariae Cum Uncis, Radix Trichosanthis, Fructus Mume, Fructus Perillae, Semen Sinapis Albae, Fructus Schisandrae Chinensis, Poria, Fluoritum, Folium Pyrrosiae, Rhizoma Polygonati Odorati, Haematitum, Carapax Trionycis, Herba Epimedii, Fructus Aurantii Immaturus, Radix Rehmanniae Preparata, Radix Scrophulariae, Radix Aconiti Lateralis Preparata, Rhizoma Dioscoreae, Rhizoma Alismatis, Rhizoma Cimicifugae, Semen Arecae, the Rhizoma Anemarrhenae.Publication No. CN 103169754 A(application number 201110407564.3) Chinese patent literature disclose a kind of Chinese medicine composition for the treatment of asthma, described Chinese medicine composition is made up of the crude drug of following weight portion: Radix Kansui 1.8-2.2 part, Semen Sinapis Albae 0.8-1.2 part, Herba Asari 0.8-1.2 part.
In modern medicine, the medicine that western medical treatment uses is cured the symptoms, not the disease, dependency and side effect larger, comparatively speaking, Chinese traditional treatment is more safe and effective, current traditional Chinese medical science formula has much, but its suitability and concrete curative effect still to be tested, so also need the research further strengthened this aspect Chinese medicine.
Summary of the invention
For the problem of prior art, the object of this invention is to provide a kind of Be very effective, take the clearing heat in YING system antidote preparation of the wide treatment asthma of safe and applicable.
Technical scheme of the present invention is:
Asthma clearing heat in YING system antidote preparation, is prepared from primarily of following bulk drugs, is weight portion: Fructus Tritici Levis 6-9; Radix Codonopsis 5-10; Folium Hyoscyami 5-9; Caulis Bambusae In Taenia 9-15; Rhizoma Atractylodis Macrocephalae preparata 6-9; Fructus Chebulae 4-8; Semen Armeniacae Amarum 6-12; Salt alkali 3-6; Lignum Aquilariae Resinatum 3-6; Herba Centellae 8-12; Scorpio 3-6.
Preferably: Fructus Tritici Levis 7-8; Radix Codonopsis 6-9; Folium Hyoscyami 6-8; Caulis Bambusae In Taenia 10-14; Rhizoma Atractylodis Macrocephalae preparata 7-8; Fructus Chebulae 5-7; Semen Armeniacae Amarum 8-10; Salt alkali 4-5; Lignum Aquilariae Resinatum 4-5; Herba Centellae 9-11; Scorpio 4-5.
More preferably: Fructus Tritici Levis 7.5; Radix Codonopsis 7.5; Folium Hyoscyami 7; Caulis Bambusae In Taenia 12; Rhizoma Atractylodis Macrocephalae preparata 7.5; Fructus Chebulae 6; Semen Armeniacae Amarum 9; Salt alkali 4.5; Lignum Aquilariae Resinatum 4.5; Herba Centellae 10; Scorpio 4.5.
Described asthma clearing heat in YING system antidote preparation, be made into pharmaceutically acceptable powder, its preparation method is:
(1) by Fructus Tritici Levis, Fructus Chebulae and Semen Armeniacae Amarum, clean remove impurity, be placed in baking box, 250 DEG C, continue 4 minutes, taking-up is dried in the air cool;
(2) get ginger slice, add decocting and become soup, by Radix Codonopsis, Folium Hyoscyami, Caulis Bambusae In Taenia, Lignum Aquilariae Resinatum and Herba Centellae bundling, be placed in ginger decoction, be heated to ginger decoction with slow fire and exhaust, taking-up, shredding, drying;
(3) cleaned by salt alkali, smash, be put in container, add the water dissolution of 3 times of weight, after filtered through gauze, add hot filtrate, evaporate, be dried into block, taking-up cools, and pulverizes;
(4) Scorpio is placed in boiling water, adds mentha leave, soak 20-30 minute (preferably: soak 22-28 minute; Be more preferably: soak 25 minutes), take out, dry;
(5) above-mentioned made medical material and Rhizoma Atractylodis Macrocephalae preparata are pulverized respectively, cross 150-180 mesh sieve (preferred: to cross 160-170 mesh sieve: be more preferably: to cross 165 mesh sieves), mixing, sterilizing encapsulate to obtain powder.
The preparation method of described asthma clearing heat in YING system antidote preparation powder, in step (2), ginger decoction did not have medical material 3-5cm(preferred: ginger decoction did not have medical material 4cm).
Described asthma clearing heat in YING system antidote preparation, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) by Fructus Tritici Levis, Fructus Chebulae and Semen Armeniacae Amarum, clean remove impurity, be placed in baking box, 250 DEG C, continue 4 minutes, taking-up is dried in the air cool;
(2) get ginger slice, add decocting and become soup, by Radix Codonopsis, Folium Hyoscyami, Caulis Bambusae In Taenia, Lignum Aquilariae Resinatum and Herba Centellae bundling, be placed in ginger decoction and do not have medical material 3cm, be heated to ginger decoction with slow fire and exhaust, taking-up, shredding, drying;
(3) cleaned by salt alkali, smash, be put in container, add the water dissolution of 3 times of weight, after filtered through gauze, add hot filtrate, evaporate, be dried into block, taking-up cools, and pulverizes;
(4) Scorpio is placed in boiling water, adds mentha leave, soak 20-30 minute (preferably: soak 22-28 minute; Be more preferably: soak 25 minutes), take out, dry;
(5) mix above-mentioned made medical material and Rhizoma Atractylodis Macrocephalae preparata, decoct with water, turn little fire after being heated to boiling and continue 30 minutes, filter to get filtrate; Residue medicinal residues, add the water of 4 times of medical material amounts, then decoct 25 minutes, filter and mix twice gained filtrate, be evaporated to the half of original volume, sterilizing encapsulates to obtain decoction.
The preparation method of described asthma clearing heat in YING system antidote preparation decoction, in step (5), amount of water is that the 6-9 of medical material gross weight is doubly (preferred: amount of water is 7-8 times of medical material gross weight; Be more preferably: amount of water is 7.5 times of medical material gross weight).
Described asthma clearing heat in YING system antidote preparation, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) by Fructus Tritici Levis, Fructus Chebulae and Semen Armeniacae Amarum, clean remove impurity, be placed in baking box, 250 DEG C, continue 4 minutes, taking-up is dried in the air cool;
(2) get ginger slice, add decocting and become soup, by Radix Codonopsis, Folium Hyoscyami, Caulis Bambusae In Taenia, Lignum Aquilariae Resinatum and Herba Centellae bundling, be placed in ginger decoction and do not have medical material 3cm, be heated to ginger decoction with slow fire and exhaust, taking-up, shredding, drying;
(3) cleaned by salt alkali, smash, be put in container, add the water dissolution of 3 times of weight, after filtered through gauze, add hot filtrate, evaporate, be dried into block, taking-up cools, and pulverizes;
(4) Scorpio is placed in boiling water, adds mentha leave, soak 20-30 minute (preferably: soak 22-28 minute; Be more preferably: soak 25 minutes), take out, dry;
(5) mix above-mentioned made medical material and Rhizoma Atractylodis Macrocephalae preparata, add the soak by water of 6 times of medical material amounts, turn little fire after being heated to boiling and continue 30 minutes, filter to get filtrate; Residue medicinal residues, add the water of 4 times of medical material amounts, then decoct 25 minutes, filter and mix twice gained filtrate, being evaporated to thick paste, obtaining unguentum.
The preparation method of described asthma clearing heat in YING system antidote preparation unguentum, being evaporated to relative density in step (5) is 1.21-1.23(60 DEG C) the thick paste of thick paste (preferred: to be evaporated to relative density 1.22(60 DEG C)).
Described asthma clearing heat in YING system antidote preparation, be made into pharmaceutically acceptable honeyed pill, its preparation method is:
(1) by Fructus Tritici Levis, Fructus Chebulae and Semen Armeniacae Amarum, clean remove impurity, be placed in baking box, 250 DEG C, continue 4 minutes, taking-up is dried in the air cool;
(2) get ginger slice, add decocting and become soup, by Radix Codonopsis, Folium Hyoscyami, Caulis Bambusae In Taenia, Lignum Aquilariae Resinatum and Herba Centellae bundling, be placed in ginger decoction and do not have medical material 3cm, be heated to ginger decoction with slow fire and exhaust, taking-up, shredding, drying;
(3) cleaned by salt alkali, smash, be put in container, add the water dissolution of 3 times of weight, after filtered through gauze, add hot filtrate, evaporate, be dried into block, taking-up cools, and pulverizes;
(4) Scorpio is placed in boiling water, adds mentha leave, soak 20-30 minute (preferably: soak 22-28 minute; Be more preferably: soak 25 minutes), take out, dry;
(5) above-mentioned made medical material and Rhizoma Atractylodis Macrocephalae preparata are pulverized respectively, cross 130-150 mesh sieve (preferred: to cross 135-145 mesh sieve; Be more preferably: cross 140 mesh sieves), then mix homogeneously with refined honey, rubbing pill, sterilization packaging obtain honeyed pill.
The preparation method of described asthma clearing heat in YING system antidote preparation honeyed pill, the ratio of step (5) Chinese medicine powder and refined honey is that 1:1-1:1.5(is preferred: the ratio of medicated powder and refined honey is 1:1.3).
Asthma clearing heat in YING system antidote pharmaceutical formulation science provided by the invention, preparation method is simple.In addition, its excellent part also shows:
1, this prescription clinical effectiveness is remarkable, has therapeutic effect significantly to asthma;
2, medicine of the present invention is natural Chinese medicine, safely, has no side effect;
3, the present invention is applicable to people's use of various age bracket, does not increase financial burden.
Detailed description of the invention
Describe technical scheme of the present invention in detail below in conjunction with embodiment and experimental example, but protection domain is not limited thereto.
The pharmacology of the present invention's main raw material of Chinese medicine used is as follows:
Fructus Tritici Levis: base is former: the fruit of the frivolous lack of filling power of drying of grass family Triticum plant Semen Tritici aestivi.Gather during fruit maturation, get the wheat grain of the frivolous and non-peeling of lack of filling power, decontamination, sieve dedust bits, with water rinse, dry.Nature and flavor: sweet are cool.Function cures mainly: only sweating due to debility, tranquilizing by nourishing the heart.For the empty hyperhidrosis of body, hysteria.
Radix Codonopsis: nature and flavor with return through: sweet, flat.Return spleen, lung meridian.Function with cure mainly: spleen invigorating lung benefiting, nourishing blood to promote the production of body fluid.For deficiency of both the splenic and pulmonary QI, lack of appetite asthenia, cough dyspnea due to deficiency, insufficiency of vital energy and blood, shallow complexion, shortness of breath and palpitation, Tianjin wound is thirsty, and interior-heat is quenched one's thirst.
Folium Hyoscyami: base is former: be the blade of plant of Solanaceae hyoscyami.Nature and flavor: bitter in the mouth; Cold in nature; Large poison.Function cures mainly: analgesia; Spasmolytic.Main epigastric pain; Toothache; Cough and asthma.
Caulis Bambusae In Taenia: base is former: the intermediate layer that the stem stalk for grass family Phyllostachys plant phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle, the blue or green pole bamboo of Thorny Sinobambusa plant, Sinocalamus plant major part allusion quotation bamboo etc. goes crust to scrape.Composition: the Caulis Bambusae In Taenia of phyllostachys nigra (lodd.ex lindl.) munro var.henonis (miff.) spapf et rendle is containing phenolic constituent: 2,5-dimethoxy-1,4-benzoquinone, hydroxy benzaldehyde, syringic aldehyde, coniferyl aldehyde.Another containing p-phthalic acid 2 '-hydroxyethyl methyl ester.The property of medicine: sweet, is slightly cold.Return spleen, stomach, gallbladder meridian.Function cures mainly: removing heat-phlegm, relieves restlessness and prevents vomiting, safe and sound removing heat from blood.Cure mainly cough due to lung-heat, dysphoria with smothery sensation is palpitated with fear, and gastric heat is vomitted oh, pregnancy reactions, frequent fetal movement, spits blood, epistaxis, hematuria, metrorrhagia.
Rhizoma Atractylodis Macrocephalae preparata: base is former: be the Preparation process product of the Rhizoma Atractylodis Macrocephalae, get Rhizoma Atractylodis Macrocephalae sheet, put in hot pot, fries to surface coke brown with moderate heat (150 ~ 180 DEG C), and water spray is a little, extinguishes Mars, takes out, dries in the air cool, sieve.Character: this product is irregular sheet, surface coke brown, section coke yellow, and matter is crisp, has burnt odor gas, mildly bitter flavor.Nature and flavor with return through: bitter, sweet, temperature.Return spleen, stomach warp.Function with cure mainly: invigorating the spleen to arrest diarrhea.For diarrhea due to hypofunction of the spleen, chronic dysentery, or the disease such as the pouring band nebulousurine of women.
Fructus Chebulae: base is former: be the dry mature fruit of Combretum Racemosum plant Fructus Chebulae or Terminalia chebula Retz. var. tomentella Kurt..Nature and flavor with return through: bitter, acid, puckery, flat.Return lung, large intestine channel.Function with cure mainly: relieving diarrhea with astringents, astringing lung-QI and relieving cough, pathogenic fire reducing sore-throat relieving.For chronic diarrhea chronic dysentery, proctoptosis of having blood in stool, the deficiency of the lung is breathed with cough, and chronic cough is more than, pharyngalgia hoarseness.
Semen Armeniacae Amarum: base is former: be the dry seed of the bitter in the mouth such as rosaceous plant Fructus Pruni or Prunus armeniaca L.var.ansu Maxim..Composition: containing amygdalin about 3%, fatty oil (almond oil) about 50%, protein and various free amino acid.Nature and flavor: bitter, temperature, poisonous.Enter lung, large intestine channel.There is expelling phlegm for arresting cough, relieving asthma, effect of intestine moistening.For controlling exogenous cough, dyspnea with fullness of the chest, sore throat, dryness of the intestine constipation.
Salt alkali: base is former: for enriched bittern cake (solid salt) decocts through processing the white crystals body made.Nature and flavor: bitter salty; Cold; Nontoxic.Gui Jing: the heart; Lung; Kidney channel.Function cures mainly: clearing away heat-fire; Reduce phlegm; Softening the hard mass; Improving eyesight.Main large hot excessive thirst; The puckery pain of wind heat conjunctival congestion; Keshan disease; Kaschin-Beck disease; Goiter; Hypertension; Rheumatic heart disease; Chronic bronchitis; Rheumatic arthritis.
Lignum Aquilariae Resinatum: nature and flavor: pungent, bitter, tepor.Gui Jing: return spleen, stomach, kidney channel.Effect: promoting the circulation of QI to relieve pain, warming middle-JIAO to arrest vomiting, helping inspiration to relieve asthma.Cure mainly: for the vexed pain of breast abdominal distention, gastrofrigid vomiting singultus, QI rising in reverse order of suffering from a deficiency of the kidney dyspnea with rapid respiration.
Herba Centellae: base is former: be dry herb or the whole herb with root of dicotyledon Umbelliferae Herba Centellae.Composition: containing the Triterpenoid of multiple α-balsam alcohol type, wherein have asiaticoside, thankuniside, isothankuniside, asiaticoside, Brahmoside, broken hot rice glycosides and Brahmic acid etc., and madasiatic acid.The property of medicine: bitter, acrid, cold.Return liver,spleen,kidney warp.Function cures mainly: heat-clearing and toxic substances removing, inducing diuresis and reducing edema.Be the long-lived medicine of Asians, can refresh oneself by beneficial brain.Research shows to have nourishing, antiinflammatory, healing of wound, diuresis relieving constipation and calm effect.Also effective in cure to leprosy, ulcer, there is activation to blood purification and immunity, because it can stimulate the replacement of deep skin cell.It is neural nourishing agent, can improve memory, alleviate mental fatigue; Also can blood pressure lowering, treatment hepatopathy etc.
Scorpio: nature and flavor with return through: pungent, flat; Poisonous.Return Liver Channel.There is endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, effect of dispersing pathogen accumulation.For liver-wind stirring up internally, spasm twitch, infantile convulsion, middle air port fish sticking its mouth out of the water, hemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
embodiment 1asthma clearing heat in YING system antidote preparation, is prepared from primarily of following bulk drugs: Fructus Tritici Levis 6g, Radix Codonopsis 5g, Folium Hyoscyami 5g, Caulis Bambusae In Taenia 9g, Rhizoma Atractylodis Macrocephalae preparata 6g, Fructus Chebulae 4g, Semen Armeniacae Amarum 6g, salt alkali 3g, Lignum Aquilariae Resinatum 3g, Herba Centellae 8g, Scorpio 3g.The preparation method of above-mentioned asthma clearing heat in YING system antidote preparation powder is:
(1) by Fructus Tritici Levis, Fructus Chebulae and Semen Armeniacae Amarum, clean remove impurity, be placed in baking box, 250 DEG C, continue 4 minutes, taking-up is dried in the air cool;
(2) get ginger slice, add decocting and become soup, by Radix Codonopsis, Folium Hyoscyami, Caulis Bambusae In Taenia, Lignum Aquilariae Resinatum and Herba Centellae bundling, be placed in ginger decoction and do not have medical material 4cm, be heated to ginger decoction with slow fire and exhaust, taking-up, shredding, drying;
(3) cleaned by salt alkali, smash, be put in container, add the water dissolution of 3 times of weight, after filtered through gauze, add hot filtrate, evaporate, be dried into block, taking-up cools, and pulverizes;
(4) Scorpio is placed in boiling water, adds mentha leave, soak 25 minutes, take out, dry;
(5) above-mentioned made medical material and Rhizoma Atractylodis Macrocephalae preparata are pulverized respectively, cross 165 mesh sieves, mixing, sterilizing encapsulate to obtain powder.
embodiment 2asthma clearing heat in YING system antidote preparation, is prepared from primarily of following bulk drugs: Fructus Tritici Levis 9g, Radix Codonopsis 10g, Folium Hyoscyami 9g, Caulis Bambusae In Taenia 15g, Rhizoma Atractylodis Macrocephalae preparata 9g, Fructus Chebulae 8g, Semen Armeniacae Amarum 12g, salt alkali 6g, Lignum Aquilariae Resinatum 6g, Herba Centellae 12g, Scorpio 6g.The preparation method of above-mentioned asthma clearing heat in YING system antidote preparation decoction is:
(1) by Fructus Tritici Levis, Fructus Chebulae and Semen Armeniacae Amarum, clean remove impurity, be placed in baking box, 250 DEG C, continue 4 minutes, taking-up is dried in the air cool;
(2) get ginger slice, add decocting and become soup, by Radix Codonopsis, Folium Hyoscyami, Caulis Bambusae In Taenia, Lignum Aquilariae Resinatum and Herba Centellae bundling, be placed in ginger decoction and do not have medical material 3cm, be heated to ginger decoction with slow fire and exhaust, taking-up, shredding, drying;
(3) cleaned by salt alkali, smash, be put in container, add the water dissolution of 3 times of weight, after filtered through gauze, add hot filtrate, evaporate, be dried into block, taking-up cools, and pulverizes;
(4) Scorpio is placed in boiling water, adds mentha leave, soak 25 minutes, take out, dry;
(5) mix above-mentioned made medical material and Rhizoma Atractylodis Macrocephalae preparata, add the soak by water of medical material gross weight 7.5 times, turn little fire after being heated to boiling and continue 30 minutes, filter to get filtrate; Residue medicinal residues, add the water of 4 times of medical material amounts, then decoct 25 minutes, filter and mix twice gained filtrate, be evaporated to the half of original volume, sterilizing encapsulates to obtain decoction.
Model case: xxx, male, 45 years old.Medical history: recurrent cough, expectoration, asthma have 2 years, and evening, cough increased the weight of, movable a little i.e. serious asthma, annual winter falls ill, easy to catch cold.Within the next few days because of sense wind and cold, the state of an illness is shown effect, and tachypnea increases the weight of, and expectorant is in white, and fear of cold, two lung is stridulated sound, is diagnosed as asthma through hospital.
Take the present embodiment gained decoction, each 50-100ml, warmly to take, one day twice five days is a course for the treatment of.After taking a course for the treatment of, patient clinical symptom is alleviated to some extent, continues two courses for the treatment of of taking medicine, and cough, expectoration disappear, what auscultation pulmonary was faint stridulate sound, a course for the treatment of of consolidate curative effect, and hospital's further consultation, all symptoms all disappear, and patient fully recovers.
embodiment 3asthma clearing heat in YING system antidote preparation, is prepared from primarily of following bulk drugs: Fructus Tritici Levis 7g, Radix Codonopsis 6g, Folium Hyoscyami 6g, Caulis Bambusae In Taenia 10g, Rhizoma Atractylodis Macrocephalae preparata 7g, Fructus Chebulae 5g, Semen Armeniacae Amarum 8g, salt alkali 4g, Lignum Aquilariae Resinatum 4g, Herba Centellae 9g, Scorpio 4g.The preparation method of above-mentioned asthma clearing heat in YING system antidote preparation unguentum is:
(1) by Fructus Tritici Levis, Fructus Chebulae and Semen Armeniacae Amarum, clean remove impurity, be placed in baking box, 250 DEG C, continue 4 minutes, taking-up is dried in the air cool;
(2) get ginger slice, add decocting and become soup, by Radix Codonopsis, Folium Hyoscyami, Caulis Bambusae In Taenia, Lignum Aquilariae Resinatum and Herba Centellae bundling, be placed in ginger decoction and do not have medical material 3cm, be heated to ginger decoction with slow fire and exhaust, taking-up, shredding, drying;
(3) cleaned by salt alkali, smash, be put in container, add the water dissolution of 3 times of weight, after filtered through gauze, add hot filtrate, evaporate, be dried into block, taking-up cools, and pulverizes;
(4) Scorpio is placed in boiling water, adds mentha leave, soak 25 minutes, take out, dry;
(5) mix above-mentioned made medical material and Rhizoma Atractylodis Macrocephalae preparata, add the soak by water of 6 times of medical material amounts, turn little fire after being heated to boiling and continue 30 minutes, filter to get filtrate; Residue medicinal residues, add the water of 4 times of medical material amounts, then decoct 25 minutes, filter and mix twice gained filtrate, being evaporated to relative density is 1.22(60 DEG C) thick paste, obtain unguentum.
Model case: xxx, women, 50 years old.Medical history: patient obtains asthma existing 3 years, since ill come resistance decline, easy to catch cold, during annual temperature cataclysm, just can cause asthma.Recently because sky cyclostrophic is cool, cough increases the weight of, abundant expectoration, rapid breathing, and activity is just coughed incessantly a little, once takes more hormone medicine, causes treatment worse and worse.
After being introduced, take the present embodiment gained unguentum, twice daily, each 4-6g, warm boiled water five days is a course for the treatment of.After taking one week, cough, expectoration take a turn for the better to some extent, and after continuing to take two courses for the treatment of, clinical symptom disappearance, patient's self-induction is fully recovered, and later six months checks, and the state of an illness does not recur.
embodiment 4asthma clearing heat in YING system antidote preparation, is prepared from primarily of following bulk drugs: Fructus Tritici Levis 8g, Radix Codonopsis 9g, Folium Hyoscyami 8g, Caulis Bambusae In Taenia 14g, Rhizoma Atractylodis Macrocephalae preparata 8g, Fructus Chebulae 7g, Semen Armeniacae Amarum 10g, salt alkali 5g, Lignum Aquilariae Resinatum 5g, Herba Centellae 11g, Scorpio 5g.The preparation method of above-mentioned asthma clearing heat in YING system antidote preparation honeyed pill is:
(1) by Fructus Tritici Levis, Fructus Chebulae and Semen Armeniacae Amarum, clean remove impurity, be placed in baking box, 250 DEG C, continue 4 minutes, taking-up is dried in the air cool;
(2) get ginger slice, add decocting and become soup, by Radix Codonopsis, Folium Hyoscyami, Caulis Bambusae In Taenia, Lignum Aquilariae Resinatum and Herba Centellae bundling, be placed in ginger decoction and do not have medical material 3cm, be heated to ginger decoction with slow fire and exhaust, taking-up, shredding, drying;
(3) cleaned by salt alkali, smash, be put in container, add the water dissolution of 3 times of weight, after filtered through gauze, add hot filtrate, evaporate, be dried into block, taking-up cools, and pulverizes;
(4) Scorpio is placed in boiling water, adds mentha leave, soak 25 minutes, take out, dry;
(5) above-mentioned made medical material and Rhizoma Atractylodis Macrocephalae preparata are pulverized respectively, cross 140 mesh sieves, according to the ratio of medicated powder and refined honey 1:1.3, mix homogeneously, rubbing pill, sterilization packaging obtain honeyed pill.
Model case: xxx, male, 5 years old.Medical history: patient occurred cough without obvious inducement before one month, with panting, panting and increasing the weight of, alleviate after sleep after activity, in persistence, through examination in hospital, find that its pair of pulmonary respiration sound is thick, expiratory phase extends, hear and two-phase wheezing sound, without fine rales, be diagnosed as asthma.
Taking this example gained honeyed pill, each two, about 5g, one day twice, warm boiled water, five days is a course for the treatment of.After taking a course for the treatment of, patient's cough, panting obviously alleviates, and after continuing to take one week, recheck to hospital, wheezing sound can not be heard substantially, also without uncomfortable disease after activity, can orthobiosis, and follow up a case by regular visits in 1 year, without recurrence.
embodiment 5asthma clearing heat in YING system antidote preparation, is prepared from primarily of following bulk drugs: Fructus Tritici Levis 7.5g, Radix Codonopsis 7.5g, Folium Hyoscyami 7g, Caulis Bambusae In Taenia 12g, Rhizoma Atractylodis Macrocephalae preparata 7.5g, Fructus Chebulae 6g, Semen Armeniacae Amarum 9g, salt alkali 4.5g, Lignum Aquilariae Resinatum 4.5g, Herba Centellae 10g, Scorpio 4.5g.The preparation method of above-mentioned asthma clearing heat in YING system antidote preparation powder is:
(1) by Fructus Tritici Levis, Fructus Chebulae and Semen Armeniacae Amarum, clean remove impurity, be placed in baking box, 250 DEG C, continue 4 minutes, taking-up is dried in the air cool;
(2) get ginger slice, add decocting and become soup, by Radix Codonopsis, Folium Hyoscyami, Caulis Bambusae In Taenia, Lignum Aquilariae Resinatum and Herba Centellae bundling, be placed in ginger decoction and do not have medical material 4cm, be heated to ginger decoction with slow fire and exhaust, taking-up, shredding, drying;
(3) cleaned by salt alkali, smash, be put in container, add the water dissolution of 3 times of weight, after filtered through gauze, add hot filtrate, evaporate, be dried into block, taking-up cools, and pulverizes;
(4) Scorpio is placed in boiling water, adds mentha leave, soak 25 minutes, take out, dry;
(5) above-mentioned made medical material and Rhizoma Atractylodis Macrocephalae preparata are pulverized respectively, cross 165 mesh sieves, mixing, sterilizing encapsulate to obtain powder.
test example 1the clinical practice of embodiment 5 gained asthma clearing heat in YING system antidote preparation powder:
Choose crowd: according to hospital outpatient case history, screening asthmatic patient 436 example, wherein women 210 example, male 226 example, the range of age 18-60 year, more than course of disease half a year.
Before test, patient is divided into two groups at random, experimental group 316 example and matched group 120 routine, two groups in sex, age, the course of disease, the state of an illness etc. without significant difference.Experimental group takes embodiment 5 gained powder, each 5-10g, and sooner or later respectively once, warm boiled water five days is a course for the treatment of; Matched group takes other conventional medicines (husky butanolamine aerosol, terbutaline sheet, aminophylline tablets and fluticasone propionate etc.).Period in a medicine carries out Continuous Observation to two groups of patients, record symptom and change.
Curative effect determinate standard: reference literature criterion of therapeutical effect, (1) is effective: asthma is not shown effect substantially, at ordinary times non-evident sympton, and auscultation two lung is without sound of stridulating; (2) effective: asthma attack number of times obviously reduces, and symptom alleviates, auscultation two lung is even to be heard and sound of stridulating; (3) invalid: asthma attack number of times and symptom are all without improvement, and auscultation two lung is often heard and sound of stridulating.
Clinical effectiveness is as shown in table 1:
The present invention is theoretical according to differential diagnosis in tcm, multiple medical material synergistic combination, there is the Fructus Tritici Levis of tranquilizing by nourishing the heart, the Radix Codonopsis of spleen invigorating lung benefiting, the Caulis Bambusae In Taenia of removing heat-phlegm, the Semen Armeniacae Amarum of relieving cough and asthma, the Herba Centellae of nourishing antiinflammatory, the Scorpio etc. of removing obstruction in the collateral to relieve pain, can the effective malaise symptoms that brings of relieving asthma disease, improves the body immunity of patient.Through the treatment of three courses for the treatment of, the total effective rate of experimental group is 97.2%, far above 82.5% of matched group.
It should be pointed out that detailed description of the invention is the more representational example of the present invention, obvious technical scheme of the present invention is not limited to above-described embodiment, can also have a lot of distortion.Those of ordinary skill in the art, with the present invention clear and definite disclosed or according to undoubted the obtaining of the written description of file, the claimed scope of this patent all should be thought.
Claims (10)
1. asthma clearing heat in YING system antidote preparation, is characterized in that, be prepared from primarily of following bulk drugs, be weight portion: Fructus Tritici Levis 6-9; Radix Codonopsis 5-10; Folium Hyoscyami 5-9; Caulis Bambusae In Taenia 9-15; Rhizoma Atractylodis Macrocephalae preparata 6-9; Fructus Chebulae 4-8; Semen Armeniacae Amarum 6-12; Salt alkali 3-6; Lignum Aquilariae Resinatum 3-6; Herba Centellae 8-12; Scorpio 3-6.
2. asthma clearing heat in YING system antidote preparation as claimed in claim 1, is characterized in that, Fructus Tritici Levis 7-8; Radix Codonopsis 6-9; Folium Hyoscyami 6-8; Caulis Bambusae In Taenia 10-14; Rhizoma Atractylodis Macrocephalae preparata 7-8; Fructus Chebulae 5-7; Semen Armeniacae Amarum 8-10; Salt alkali 4-5; Lignum Aquilariae Resinatum 4-5; Herba Centellae 9-11; Scorpio 4-5(is preferably: Fructus Tritici Levis 7.5; Radix Codonopsis 7.5; Folium Hyoscyami 7; Caulis Bambusae In Taenia 12; Rhizoma Atractylodis Macrocephalae preparata 7.5; Fructus Chebulae 6; Semen Armeniacae Amarum 9; Salt alkali 4.5; Lignum Aquilariae Resinatum 4.5; Herba Centellae 10; Scorpio 4.5).
3. the asthma clearing heat in YING system antidote preparation as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable powder, its preparation method is:
(1) by Fructus Tritici Levis, Fructus Chebulae and Semen Armeniacae Amarum, clean remove impurity, be placed in baking box, 250 DEG C, continue 4 minutes, taking-up is dried in the air cool;
(2) get ginger slice, add decocting and become soup, by Radix Codonopsis, Folium Hyoscyami, Caulis Bambusae In Taenia, Lignum Aquilariae Resinatum and Herba Centellae bundling, be placed in ginger decoction, be heated to ginger decoction with slow fire and exhaust, taking-up, shredding, drying;
(3) cleaned by salt alkali, smash, be put in container, add the water dissolution of 3 times of weight, after filtered through gauze, add hot filtrate, evaporate, be dried into block, taking-up cools, and pulverizes;
(4) Scorpio is placed in boiling water, adds mentha leave, soak 20-30 minute (preferably: soak 22-28 minute; Be more preferably: soak 25 minutes), take out, dry;
(5) above-mentioned made medical material and Rhizoma Atractylodis Macrocephalae preparata are pulverized respectively, cross 150-180 mesh sieve (preferred: to cross 160-170 mesh sieve: be more preferably: to cross 165 mesh sieves), mixing, sterilizing encapsulate to obtain powder.
4. the preparation method of asthma clearing heat in YING system antidote preparation powder as claimed in claim 3, is characterized in that, in step (2), ginger decoction did not have medical material 3-5cm(preferred: ginger decoction did not have medical material 4cm).
5. the asthma clearing heat in YING system antidote preparation as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable decoction, its preparation method is:
(1) by Fructus Tritici Levis, Fructus Chebulae and Semen Armeniacae Amarum, clean remove impurity, be placed in baking box, 250 DEG C, continue 4 minutes, taking-up is dried in the air cool;
(2) get ginger slice, add decocting and become soup, by Radix Codonopsis, Folium Hyoscyami, Caulis Bambusae In Taenia, Lignum Aquilariae Resinatum and Herba Centellae bundling, be placed in ginger decoction and do not have medical material 3cm, be heated to ginger decoction with slow fire and exhaust, taking-up, shredding, drying;
(3) cleaned by salt alkali, smash, be put in container, add the water dissolution of 3 times of weight, after filtered through gauze, add hot filtrate, evaporate, be dried into block, taking-up cools, and pulverizes;
(4) Scorpio is placed in boiling water, adds mentha leave, soak 20-30 minute (preferably: soak 22-28 minute; Be more preferably: soak 25 minutes), take out, dry;
(5) mix above-mentioned made medical material and Rhizoma Atractylodis Macrocephalae preparata, decoct with water, turn little fire after being heated to boiling and continue 30 minutes, filter to get filtrate; Residue medicinal residues, add the water of 4 times of medical material amounts, then decoct 25 minutes, filter and mix twice gained filtrate, be evaporated to the half of original volume, sterilizing encapsulates to obtain decoction.
6. the preparation method of asthma clearing heat in YING system antidote preparation decoction as claimed in claim 5, is characterized in that, in step (5), amount of water is that the 6-9 of medical material gross weight is doubly (preferred: amount of water is 7-8 times of medical material gross weight; Be more preferably: amount of water is 7.5 times of medical material gross weight).
7. the asthma clearing heat in YING system antidote preparation as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable unguentum, its preparation method is:
(1) by Fructus Tritici Levis, Fructus Chebulae and Semen Armeniacae Amarum, clean remove impurity, be placed in baking box, 250 DEG C, continue 4 minutes, taking-up is dried in the air cool;
(2) get ginger slice, add decocting and become soup, by Radix Codonopsis, Folium Hyoscyami, Caulis Bambusae In Taenia, Lignum Aquilariae Resinatum and Herba Centellae bundling, be placed in ginger decoction and do not have medical material 3cm, be heated to ginger decoction with slow fire and exhaust, taking-up, shredding, drying;
(3) cleaned by salt alkali, smash, be put in container, add the water dissolution of 3 times of weight, after filtered through gauze, add hot filtrate, evaporate, be dried into block, taking-up cools, and pulverizes;
(4) Scorpio is placed in boiling water, adds mentha leave, soak 20-30 minute (preferably: soak 22-28 minute; Be more preferably: soak 25 minutes), take out, dry;
(5) mix above-mentioned made medical material and Rhizoma Atractylodis Macrocephalae preparata, add the soak by water of 6 times of medical material amounts, turn little fire after being heated to boiling and continue 30 minutes, filter to get filtrate; Residue medicinal residues, add the water of 4 times of medical material amounts, then decoct 25 minutes, filter and mix twice gained filtrate, being evaporated to thick paste, obtaining unguentum.
8. the preparation method of asthma clearing heat in YING system antidote preparation unguentum as claimed in claim 7, it is characterized in that, being evaporated to relative density in step (5) is 1.21-1.23(60 DEG C) the thick paste of thick paste (preferred: be evaporated to relative density 1.22(60 DEG C)).
9. the asthma clearing heat in YING system antidote preparation as described in as arbitrary in claim 1-2, it is characterized in that, be made into pharmaceutically acceptable honeyed pill, its preparation method is:
(1) by Fructus Tritici Levis, Fructus Chebulae and Semen Armeniacae Amarum, clean remove impurity, be placed in baking box, 250 DEG C, continue 4 minutes, taking-up is dried in the air cool;
(2) get ginger slice, add decocting and become soup, by Radix Codonopsis, Folium Hyoscyami, Caulis Bambusae In Taenia, Lignum Aquilariae Resinatum and Herba Centellae bundling, be placed in ginger decoction and do not have medical material 3cm, be heated to ginger decoction with slow fire and exhaust, taking-up, shredding, drying;
(3) cleaned by salt alkali, smash, be put in container, add the water dissolution of 3 times of weight, after filtered through gauze, add hot filtrate, evaporate, be dried into block, taking-up cools, and pulverizes;
(4) Scorpio is placed in boiling water, adds mentha leave, soak 20-30 minute (preferably: soak 22-28 minute; Be more preferably: soak 25 minutes), take out, dry;
(5) above-mentioned made medical material and Rhizoma Atractylodis Macrocephalae preparata are pulverized respectively, cross 130-150 mesh sieve (preferred: to cross 135-145 mesh sieve; Be more preferably: cross 140 mesh sieves), then mix homogeneously with refined honey, rubbing pill, sterilization packaging obtain honeyed pill.
10. the preparation method of asthma clearing heat in YING system antidote preparation honeyed pill as claimed in claim 9, it is characterized in that, the ratio of step (5) Chinese medicine powder and refined honey is that 1:1-1:1.5(is preferred: the ratio of medicated powder and refined honey is 1:1.3).
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1616015A (en) * | 2004-09-14 | 2005-05-18 | 吴业华 | Medicine for treating asthma disease and its preparing method |
| CN103784637A (en) * | 2012-10-29 | 2014-05-14 | 刘黎明 | Traditional Chinese medicine decoction used for preventing and treating children spleen deficiency type asthma |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1616015A (en) * | 2004-09-14 | 2005-05-18 | 吴业华 | Medicine for treating asthma disease and its preparing method |
| CN103784637A (en) * | 2012-10-29 | 2014-05-14 | 刘黎明 | Traditional Chinese medicine decoction used for preventing and treating children spleen deficiency type asthma |
Non-Patent Citations (1)
| Title |
|---|
| 王灵台: "中医中药防治支气管哮喘的研究进展", 《上海中医药杂志》 * |
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