CN104435833A - Traditional Chinese drug for treating secondary thrombocytosis - Google Patents

Traditional Chinese drug for treating secondary thrombocytosis Download PDF

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CN104435833A
CN104435833A CN201410687974.1A CN201410687974A CN104435833A CN 104435833 A CN104435833 A CN 104435833A CN 201410687974 A CN201410687974 A CN 201410687974A CN 104435833 A CN104435833 A CN 104435833A
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radix
herba
blood
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徐玉文
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Abstract

The invention discloses a traditional Chinese drug for treating secondary thrombocytosis. The traditional Chinese drug is prepared from the following ingredients in parts by weight: 20 parts of root of wallich swallowwort, 15 parts of llex cornuta lindl, 18 parts of raspberry, 20 parts of Gentiana sarcorrhiza Ling et Ma, 12 parts of tiger ginger, 15 parts of white chicken gizzard, 12 parts of blackend swallowwort root, 15 parts of sibirica walking fern herb, 20 parts of Fructus Livistonae, 12 parts of Galium spurium L., 15 parts of Impetiens loulanensis Hook.f., 12 parts of jambu air, 12 parts of Ligustrum groffiae Merr., 15 parts of pinfa raspberry root and leaf, 15 parts of flos primulae secundiflorae, 15 parts of liquidambar formosana hance, 15 parts of pilose actinodaphne leaf, 18 parts of maize root, 12 parts of phlegm drugs, 12 parts of Alga Eucheumae, 20 parts of water deer's bone, 18 parts of alder-leaved mountain ash fruits, 12 parts of tiny ardisia, 15 parts of conic gymnadenia tuber, 15 parts of angled jute, 15 parts of Persicaria perfoliata and 5 parts of liquorice. The traditional Chinese drug is good in treatment effect, high in curative effect and free from relapse after healing.

Description

A kind of Chinese medicine for the treatment of secondary thrombocythemia
Technical field
The present invention relates to a kind of Chinese medicine, particularly a kind of Chinese medicine being used for the treatment of secondary thrombocythemia.
Background technology
Secondary thrombocythemia is mainly seen in chronic infection, malignant tumor, acute bleeding, hemolytic anemia, the platelet that the reaction of operating medicine and connective tissue disease cause excessively generates, generally asymptomatic, some patients can have thrombosis, and peripheral blood platelet is higher than normal >400 × 109/L.The thrombocytosis of secondary thrombocythemia, great majority are caused by thrombocytopoiesis accelerates.Secondary cases thrombocytosis is found in numerous disease or physiological conditions, can sort out as follows: malignant tumor (comprising hematologic malignancies); Chronic inflammatory disease (connective tissue disease, tuberculosis, liver cirrhosis, chronic pancreatitis, chronic pneumonia, arteritis); Acute inflammation infects; Acute bleeding; Iron deficiency anemia; Hemolytic anemia; Operation (splenectomy and other surgical operations); Drug reaction (vincristine, epinephrine, Interleukin-1β); Motor reaction; (knock-on) (stop using bone marrow depression medicine, ethanol, after VitBl2 lacks treatment) is recovered after thrombocytopenia; Other (premature infant, baby VitE lack, osteoporosis, heart disease, renal transplantation, diabetes insipidus, gestation, renal failure).At present, treatment thrombocytosis traditional remedies mainly contains four kinds, and one is Drug therapy, such as busulfan, hydroxyurea, radio-isotope phosphorus, adopts Drug therapy quick result, but easily repeatedly; Two is the treatments of platelet exclusion, although can reduce platelet counts rapidly, this therapy is only for more serious bleeding, and such as gastrointestinal hemorrhage, pregnancy and delivery are hemorrhage, frequent plateletphoresis can accelerate the development of this disease, also can cause the complication etc. such as body too little iron; 3rd, interferon therapy, interferon therapy can reduce platelet fast, but clinical response is larger, and a lot of people is difficult to adhere to for a long time injection, and the common untoward reaction of interferon is flu syndrome.Performance has heating, shiver with cold, general malaise, myalgia, headache etc., sometimes also can occur nasal obstruction, watery nasal discharge, dizziness, urgent micturition etc., and the most common with heating.Endocrine, metabolism disorder, easily there is dysthyreosis in long-term prescription person; Also can cause the reduction of decrease in estrogen, HDL-C in addition, triglyceride raises, glucose in urine raises, accidental hyperkalemia, the diseases such as low blood calcium; 4th, venesection, blood volume can be made within a short period of time to be down to normally, and symptom alleviates, and reduces hemorrhage and thrombosis chance.But the frequent blood-letting of clinical observation can accelerate the development of this disease, also can cause the complication etc. such as body too little iron.Treatment by Chinese herbs is good therapeutic modality.But Chinese medicine disclosed at present, also exists the defect that cure rate is lower.
Summary of the invention
Object of the present invention aims to provide a kind of Chinese medicine for the treatment of secondary thrombocythemia, by selecting suitable medical material and proportioning thereof, reaches the object of safe and effective healing secondary thrombocythemia.
For achieving the above object, the present invention is by the following technical solutions: a kind of Chinese medicine for the treatment of secondary thrombocythemia, it is characterized in that being made up of the medical material of following weight proportion: Radix cynanchi wallichii 20 parts, Radix Ilicis Cornutae 15 parts, Fructus Rubi 18 parts, money joins 20 parts, Rhizoma Polygonati Cirrhifolii 12 parts, Cold boiled chicken gizzard 15 parts, Radix Cynanchi Atrati 12 parts, Herba Camptosori Sibirici 15 parts, Chinese fanpalm seed 20 parts, Galium spurium L. 12 parts, light dish 15 parts, Eugenia javanica Lam 12 parts, Ligustrum groffiae Merr. 12 parts, Radix seu Folium Rubi Pinfaensis 15 parts, band leaf Flos Primulae Vittatae 15 parts, Resina Liquidambaris 15 parts, 15 parts, Cortex Seu Folium Actinodaphnes Pilosae leaf, Radix Maydis 18 parts, expectorant medicine 12 parts, Eucheuma gelatinosum 12 parts, Os Hydropotes inermis 20 parts, Fructus Sorbi Alnifoliae 18 parts, Herba Ardisiae Pusillae 12 parts, Rhizoma Gymnadeniae 15 parts, Herba corchori acutanguli 15 parts, Herba Polygoni Perfoliati 15 parts, 5 parts, Radix Glycyrrhizae.
Source and the function of the various Chinese crude drugs adopted in formula cure mainly as follows:
Radix cynanchi wallichii [source] medical material Ji Yuan: be the root of dicotyledon medicine asclepiadaceae plant Cynanchum Wallichii.[nature and flavor] are sweet; Micro-hardship; Temperature.[return through] liver; Kidney channel.[function cures mainly] invigorating the liver and kidney; Bone and muscle strengthening.Main lumbago due to renal deficiency; The foot and knee being feeble; Traumatic injury damages appoints; Fracture; Lyssodexis
The root that Radix Ilicis Cornutae [source] is holly plant Ilex cornuta Lindl..[nature and flavor] are bitter, are slightly cold, nontoxic.[function cures mainly] invigorating the liver and kidney, fresh breeze heat.Control waist knee flaccidity, arthralgia, wind syndrome of head, acute conjunctivitis, toothache.
The immature fruit that Fructus Rubi [source] is rosaceous plant Fructus Rubi, rubus coreanus etc.[nature and flavor] sweet acid, flat.[return through] enters liver, kidney two warp.[function cures mainly] invigorating the liver and kidney, urine reducing, supporing yang, controlling nocturnal emission with astringent drugs, improving eyesight.Control sexual impotence, seminal emission, frequency of micturition, incontinence of urine, asthenia, order is dark.
Money ginseng [source] Gentianaceae agueweed money ginseng Gentiana sarcorrhiza Ling et Ma, is used as medicine with herb or root.[nature and flavor] are sweet, temperature.[function cures mainly] invigorating the spleen and benefiting QI, tonifying the kidney to consolidate the essence.For body is empty after being ill, infantile malnutrition, cough due to deficiency of the lung, seminal emission, the enuresis, deficiency-heat is not moved back, children's's chronic diarrhea.
The rhizome that Rhizoma Polygonati Cirrhifolii [source] is liliaceous plant polygonatum cirrhifolium Royle.[nature and flavor] Gan Xin is flat.[function cures mainly] nourishing lung-YIN, invigorating the spleen and benefiting QI, hemostasis of eliminating the phlegm, subduing swelling and detoxicating.Control chronic consumptive disease cough, dizzy, lack of appetite, seminal emission, night sweat, bleeding not during menses, puerperal, body lost, and spitted blood, epistaxis, traumatic hemorrhage, laryngopharynx swelling and pain, and skin ulcer swells, scrofula.
Cold boiled chicken gizzard [source] medical material Ji Yuan: be root and the fruit of Celastraceae plant square roundleaf winged euonymus.[nature and flavor] are bitter; Puckery; Cold; Slightly poisonous.[function cures mainly] cooling blood for hemostasis.Main heat in blood epistaxis.
Radix Cynanchi Atrati [source] medical material Ji Yuan: be the root of asclepiadaceae plant Radix Cynanchi Atrati or Cynanchum versicolor Bunge.[nature and flavor] bitter in the mouth; Salty; Cold in nature.[return through] lung; Stomach; Liver.[function cures mainly] heat clearing away tonifying YIN; Inducing diuresis for treating stranguria syndrome; Detoxification sore treatment.Cure mainly warm; Fever of the body macule; Hectic fever hectic fever due to YIN-deficiency; Cough due to lung-heat; Puerperal fidgets due to deficiency; Pyretic stranguria; Stranguria with blood; Laryngopharynx swelling and pain; Sore and toxic; Venom.
Herba Camptosori Sibirici [source] medical material Ji Yuan: be the herb of Aspleniaceae plant walking fern.[nature and flavor] are light; Flat.[return through] heart channel.[function cures mainly] blood circulation promoting and blood stasis dispelling; Hemostasis; Removing toxic substances.Cure mainly thromboangiitis obliterans; Hemiplegia; Metrorrhagia; Traumatic hemorrhage; Neurodermatitis; Ulcer of the lower limb.
Chinese fanpalm seed [source] medical material Ji Yuan: be the seed of babassu Semen livistonae chinensis.[nature and flavor] sweet in the mouth; Bitter; Property is put down; Mild toxicity.[function cures mainly] blood circulation promoting and blood stasis dispelling; Hard masses softening and resolving.Cure mainly chronic hepatitis; Lump in the abdomen.
Galium spurium L. [source] medical material Ji Yuan: be the herb of Maguireothamnus speciosus Galium spurium L..[nature and flavor] are sweet; Pungent; Micro-hardship; Flat.[function cures mainly] heat-clearing and toxic substances removing; Promoting blood circulation to remove obstruction in the collateral; Stop blooding treating stranguria.Cure mainly stranguria; Hematuria; Appendicitis; Paronychia; Traumatic injury; Bones and muscles pain.
Light dish [source] medical material Ji Yuan: be the herb of Balsaminaceae plant south of road Flos Impatientis.[function cures mainly] promoting blood circulation to remove obstruction in the collateral; Removing toxic substances.Cure mainly traumatic injury; Venom.
Eugenia javanica Lam [source] medical material Ji Yuan: be leaf or the bark of myrtle wax jambo.[nature and flavor] bitter in the mouth; Cold in nature.[return through] GUIXIN; Liver Channel.[function cures mainly] eliminating fire and detoxication; Dampness removing to stop itchin.Cure mainly aphtha of the mouth and tongue; Thrush; Skin infection wets rotten; Pudendal pruritus.
Ligustrum groffiae Merr. [source] medical material Ji Yuan: be branch, the leaf of the little wax of Oleaceae plants light calyx.[nature and flavor] are bitter; Cold in nature.[return through] heart; Lung meridian.[function cures mainly] eliminating fire and detoxication.Cure mainly pharyngolaryngitis; Stomatitis; Carbuncle sore tumefacting virus; Traumatic injury; Scald.
Radix seu Folium Rubi Pinfaensis [source] medical material Ji Yuan: be the root of the red hair Fructus Rubi corchorifolii Immaturus of rosaceous plant.[nature and flavor] acid is salty; Cool.[return through] liver; Kidney channel.[function cures mainly] cooling blood for hemostasis, expelling wind and removing dampness, detoxification sore treatment.Cure mainly heat in blood to spit blood, hematuria, has blood in stool, metrorrhagia, rheumatic arthritis, scrofula, eczema, leukorrhagia.
Band leaf Flos Primulae Vittatae [source] medical material Ji Yuan: be the Ofthe Primulaceae flower flower of heralding spring partially.[nature and flavor] are bitter; Cold in nature.[function cures mainly] removing fire from the liver; Clearing away damp-heat.Cure mainly infantile hyperpyrexia convulsion; Damp-heat dysentery.
The resin that Resina Liquidambaris [source] is Hamamelidaceae Plants sweetgum.[nature and flavor] acrid in the mouth is bitter, flat, nontoxic.[return through] enters spleen, liver two warp.[function cures mainly] invigorates blood circulation, removing heat from blood, removing toxic substances, pain relieving.Control carbuncle, skin ulcer scabies, urticaria, scrofula, incised wound, toothache, spit blood, epistaxis.
Cortex Seu Folium Actinodaphnes Pilosae leaf [source] medical material Ji Yuan: be the leaf in the false beautiful osmanthus of Ulmaceae.[nature and flavor] are pungent; Property is put down.[function cures mainly] hemostasis by removing blood stasis.Main traumatic injury; Traumatic hemorrhage.
Zeistic of Radix Maydis [source] grass.[nature and flavor] sweet in the mouth; Property is put down.[return through] heart; Kidney; Urinary bladder channel.[function cures mainly] inducing diuresis for treating stranguria syndrome; Hemostasis by removing blood stasis.Main dysuria; Edema; Sand Stranguria; Stomachache; Spit blood.
Expectorant medicine [source] Celastraceae burning buss Flos Caryophylli winged euonymus Euonymus grandiflorus Wall. and Euonymus carnosus E. carnosus Hemsl., is used as medicine with root.[nature and flavor] micro-hardship, puckery, flat.[function cures mainly] hard masses softening and resolving, expelling wind and removing dampness, dredge the meridian passage.For tuberculous lymphadenitis, traumatic injury, lumbago due to renal deficiency, rheumatalgia, amenorrhea, dysmenorrhea.
Eucheuma gelatinosum [source] medical material Ji Yuan: be the frond of Hong Ling dish section plant Eucheuma gelatinosum.[nature and flavor] are sweet; Salty; Cold; Nontoxic.[return through] lung; Liver; Large intestine channel.[function cures mainly] removing heat from the lung and dissipating phlegm; Hard masses softening and resolving; Removing toxic substances.Main phlegm-heat cough; Gall subcutaneous nodule; Swelling and pain of hemorrhoid or hematochezia; Enteritis
The skeleton that Os Hydropotes inermis [source] is animal in deer family river deer.[nature and flavor] sweet in the mouth; Slightly warm in nature.[return through] spleen; Kidney channel.[function cures mainly] tonifying deficiency; Benefit marrow.The main deficient soreness of waist; Spermatorrhea.
The fruit that Fructus Sorbi Alnifoliae [source] is Flos Rosae Multiflorae kind of plant Sorbus alnifolia.[nature and flavor] are sweet; Flat.[return through] spleen; Liver.[function cures mainly] nourishes blood tonify deficiency.Main blood deficiency and yellow complexion, overstrain is weak.
Herba Ardisiae Pusillae [source] is the Herb of Myrsinacea vegetable hair stem Herba Ardisiae Japonicae.[nature and flavor] are bitter; Pungent; Property is put down.[return through] liver; Kidney channel.[function cures mainly] falls apart wind heat; Resolving toxin and disinhibiting the throat.Main cold anemopyretic; Cough; Laryngopharynx swelling and pain.
The tuber that Rhizoma Gymnadeniae [source] is orchid Rhizoma Gymnadeniae and gymnadenia crassinervis Finet.[nature and flavor] are sweet, flat.[return through] enters lung, spleen, stomach warp.[function cures mainly] benefiting vital QI and blood, promoting the production of body fluid to quench thirst.Control cough and asthma due to lung deficiency, asthenia is become thin, neurasthenia, and chronic diarrhea is lost blood, leukorrhagia, and breast is few, chronic hepatitis.
The herb that Herba corchori acutanguli [source] is Tiliaceae plant Herba corchori acutanguli.[nature and flavor] are lightly seasoned, cold in nature.[function cures mainly] heat-clearing and toxic substances removing.Control measles, profit under calentura, mange skin ulcer swells.
The herb that Herba Polygoni Perfoliati [source] is polygonaceae plant Herba Polygoni Perfoliati.[nature and flavor] acid; Bitter; Property is put down.[return through] lung; Small intestine meridian.[function cures mainly] heat-clearing and toxic substances removing; Inducing diuresis and reducing edema; Dissipating blood stasis stops blooding.Main furuncle carbuncle; Erysipelas; The paralysis cheek; Mastitis; Ting ear; Throat moth; Cold, fever; Cough due to lung-heat; Pertussis; Scrofula; Haemorrhoids; Lymphogranuloma inguinale inguinal bubo; Dysentery; Jaundice; Tympanites; Edema; Stranguria with turbid discharge; Leukorrhagia; Malaria; Wind-fire acute conjunctivitis; Treating swelling and pain by traumatic injury; Spit blood; Have blood in stool; Snake bite and insect sting.
Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
The traditional Chinese medical science thinks that secondary thrombocythemia belongs to traditional Chinese medical science mass in the abdomen category, and it enters blood impairing the liver because of malicious heresy and causes.The traditional Chinese medical science thinks that blood stored in the liver, liver are that blood is dirty, and malicious heresy enters blood impairing the liver, and poison enters Liver Channel, hinders blood vessels normally to run, forms blood stasis, and blood stasis is raw and form enclosed mass, is exactly the said spleen of people, hepatomegaly.Poison evil damage bone marrow, forms a series or multiple serial hematopoetic cell malignancies propagation.The pathogenesis of primary disease is blood stasis, blocks mechanism of qi because of blood stasis, makes the malicious evil stasis of blood stagnant.Therapeutic Principle is blood circulation promoting and blood stasis dispelling, hard masses softening and resolving, Fuzheng Jiedu.The present invention adopts the formula of science, and the Radix cynanchi wallichii adopted in formula has effect of invigorating the liver and kidney, bone and muscle strengthening; Radix Ilicis Cornutae has effect of invigorating the liver and kidney, fresh breeze heat; Fructus Rubi has effect of invigorating the liver and kidney, urine reducing, supporing yang, controlling nocturnal emission with astringent drugs, improving eyesight; Money ginseng has effect of invigorating the spleen and benefiting QI, tonifying the kidney to consolidate the essence; Rhizoma Polygonati Cirrhifolii has effect of nourishing lung-YIN, invigorating the spleen and benefiting QI, eliminate the phlegm hemostasis, subduing swelling and detoxicating; Cold boiled chicken gizzard has effect of cooling blood for hemostasis; Radix Cynanchi Atrati has effect of heat clearing away tonifying YIN, inducing diuresis for treating stranguria syndrome, detoxification sore treatment; Herba Camptosori Sibirici has effect of blood circulation promoting and blood stasis dispelling, hemostasis, removing toxic substances; Chinese fanpalm seed has effect of blood circulation promoting and blood stasis dispelling, hard masses softening and resolving; Galium spurium L. has heat-clearing and toxic substances removing, promoting blood circulation to remove obstruction in the collateral, effect that hemostasis is treating stranguria; Light dish has effect of promoting blood circulation to remove obstruction in the collateral, removing toxic substances; Eugenia javanica Lam has effect of eliminating fire and detoxication, dampness removing to stop itchin; Ligustrum groffiae Merr. has effect of eliminating fire and detoxication; Radix seu Folium Rubi Pinfaensis has effect of cooling blood for hemostasis, expelling wind and removing dampness, detoxification sore treatment; There is with leaf Flos Primulae Vittatae effect of removing fire from the liver, clearing away damp-heat; Resina Liquidambaris have invigorate blood circulation, removing heat from blood, removing toxic substances, pain relieving effect; Cortex Seu Folium Actinodaphnes Pilosae leaf has effect of hemostasis by removing blood stasis; Radix Maydis has effect of inducing diuresis for treating stranguria syndrome, hemostasis by removing blood stasis; Expectorant medical instrument has effect of hard masses softening and resolving, expelling wind and removing dampness, dredge the meridian passage; Eucheuma gelatinosum has effect of removing heat from the lung and dissipating phlegm, hard masses softening and resolving, removing toxic substances; Os Hydropotes inermis has effect of tonifying deficiency, beneficial marrow; Fructus Sorbi Alnifoliae has the effect of the tonify deficiency that nourishes blood; Herba Ardisiae Pusillae has effect of loose wind heat, resolving toxin and disinhibiting the throat; Rhizoma Gymnadeniae has effect of benefiting vital QI and blood, promoting the production of body fluid to quench thirst; Herba corchori acutanguli has effect of heat-clearing and toxic substances removing; Herba Polygoni Perfoliati has effect of heat-clearing and toxic substances removing, the hemostasis of inducing diuresis and reducing edema, dissipating blood stasis; Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.The present invention starts with from causing the reason of secondary thrombocythemia, carries out the formula of science, and each medicine in formula cooperatively interacts, synergism, made Chinese medicine has blood circulation promoting and blood stasis dispelling, effect of hard masses softening and resolving, Fuzheng Jiedu, effectively can treat secondary thrombocythemia.For many years, by showing the use of 45 patients, effective percentage reaches 95.5%, and therapeutic effect is good, no longer recurs more.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
Since in November, 2004 to 2012 year December, our unit have collected the patient of 45 routine secondary thrombocythemias, wherein, male 30 example, women 15 example, age, from 44-80 year, mainly causes because of reasons such as chronic inflammatory disease, acute inflammation infection, acute bleeding, iron deficiency anemia, hemolytic anemia, splenectomy operation, heart disease, diabetes insipiduss.According to the severe extent of patient, be divided into slight, moderate, severe.Wherein, patients with mild has 18 examples, and clinical symptoms shows as giddy, weak symptom; Moderate patient has 21 examples, and clinical manifestation is cause because of acute inflammation infection, acute bleeding, diabetes insipidus etc. hemorrhage; Patient with severe symptoms has 6 examples, shows as the hemorrhage and thrombosis caused because of operation and heart and brain disease etc.Hemorrhage is often spontaneous, recurrent exerbation.Patient takes the present invention by after the obtained medicine of embodiment 1, and 20 days to about one month, platelet just had obvious reduction, the lighter treats and can fully recover for about 1 month, can fully recover in a moderate patient treatment 2-3 month left side, about severe patient treatment 4-5 month, can fully recover.
The Main Diagnosis standard of secondary thrombocythemia: 1. clinical have hemorrhage or (with) thrombosis medical history; 2. splenomegaly; 3. platelet count >1000 × 109/L, numeration of leukocyte <30 × 109/L, Lactoferrin is normal or lower, but RBC number does not increase; 4. myelosis, megakaryocytic series hypertrophy is obvious; 5. leukocyte and platelet basic phosphatase increase; 6. can except secondary thrombocythemia and other myeloproliferative disease.
The criterion of therapeutical effect of secondary thrombocythemia:
Clinical recovery: the various clinical symptom disappearance of secondary thrombocythemia or substantially disappear, the indexs such as various hemogram index, bone marrow smear index, coagulogram all reach normal person's standard; Effective: the clinical symptoms of secondary thrombocythemia is obviously improved, the indexs such as various hemogram index, bone marrow smear index, coagulogram are also obviously improved; Effective: the clinical symptoms of secondary thrombocythemia takes a turn for the better, and the indexs such as various hemogram index, bone marrow smear index, coagulogram also take a turn for the better; Invalid: the clinical symptoms of secondary thrombocythemia is not improved or increases the weight of, the indexs such as various hemogram index, bone marrow smear index, coagulogram are without improvement or increase the weight of.
Treatment statistical result sees the following form
As can be seen here, medicine of the present invention effectively can treat secondary thrombocythemia.
Detailed description of the invention
Below in conjunction with the concrete example implemented, further detailed description is done to the present invention.
Embodiment 1
Take Radix cynanchi wallichii 20 grams, Radix Ilicis Cornutae 15 grams, Fructus Rubi 18 grams, money joins 20 grams, Rhizoma Polygonati Cirrhifolii 12 grams, Cold boiled chicken gizzard 15 grams, Radix Cynanchi Atrati 12 grams, Herba Camptosori Sibirici 15 grams, Chinese fanpalm seed 20 grams, Galium spurium L. 12 grams, light dish 15 grams, Eugenia javanica Lam 12 grams, Ligustrum groffiae Merr. 12 grams, Radix seu Folium Rubi Pinfaensis 15 grams, band leaf Flos Primulae Vittatae 15 grams, Resina Liquidambaris 15 grams, 15 grams, Cortex Seu Folium Actinodaphnes Pilosae leaf, Radix Maydis 18 grams, expectorant medicine 12 grams, Eucheuma gelatinosum 12 grams, Os Hydropotes inermis 20 grams, Fructus Sorbi Alnifoliae 18 grams, Herba Ardisiae Pusillae 12 grams, Rhizoma Gymnadeniae 15 grams, Herba corchori acutanguli 15 grams, Herba Polygoni Perfoliati 15 grams, 5 grams, Radix Glycyrrhizae, add 8 times of water gagings, decoct 1.5 hours, filter, filtering residue adds 6 times of water gagings, decocts 1 hour, filters, merging filtrate, concentrated, packaging, must meet the medicinal liquid of adult normal's 1 day consumption.
Be used for the treatment of secondary thrombocythemia.Oral, every bu early, late secondary takes.
Specific embodiment 2
Take Radix cynanchi wallichii 20 grams, Radix Ilicis Cornutae 15 grams, Fructus Rubi 18 grams, money joins 20 grams, Rhizoma Polygonati Cirrhifolii 12 grams, Cold boiled chicken gizzard 15 grams, Radix Cynanchi Atrati 12 grams, Herba Camptosori Sibirici 15 grams, Chinese fanpalm seed 20 grams, Galium spurium L. 12 grams, light dish 15 grams, Eugenia javanica Lam 12 grams, Ligustrum groffiae Merr. 12 grams, Radix seu Folium Rubi Pinfaensis 15 grams, band leaf Flos Primulae Vittatae 15 grams, Resina Liquidambaris 15 grams, 15 grams, Cortex Seu Folium Actinodaphnes Pilosae leaf, Radix Maydis 18 grams, expectorant medicine 12 grams, Eucheuma gelatinosum 12 grams, Os Hydropotes inermis 20 grams, Fructus Sorbi Alnifoliae 18 grams, Herba Ardisiae Pusillae 12 grams, Rhizoma Gymnadeniae 15 grams, Herba corchori acutanguli 15 grams, Herba Polygoni Perfoliati 15 grams, 5 grams, Radix Glycyrrhizae, add 10 times of water gagings, decoct 2 hours, filter, filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters, merging filtrate, concentrated, dry, packaging, must meet the powder of adult normal's 1 day consumption.
Be used for the treatment of secondary thrombocythemia.Oral, every bu is taken for early, middle and late three times.
Specific embodiment 3
Take Radix cynanchi wallichii 20 grams, Radix Ilicis Cornutae 15 grams, Fructus Rubi 18 grams, money joins 20 grams, Rhizoma Polygonati Cirrhifolii 12 grams, Cold boiled chicken gizzard 15 grams, Radix Cynanchi Atrati 12 grams, Herba Camptosori Sibirici 15 grams, Chinese fanpalm seed 20 grams, Galium spurium L. 12 grams, light dish 15 grams, Eugenia javanica Lam 12 grams, Ligustrum groffiae Merr. 12 grams, Radix seu Folium Rubi Pinfaensis 15 grams, band leaf Flos Primulae Vittatae 15 grams, Resina Liquidambaris 15 grams, 15 grams, Cortex Seu Folium Actinodaphnes Pilosae leaf, Radix Maydis 18 grams, expectorant medicine 12 grams, Eucheuma gelatinosum 12 grams, Os Hydropotes inermis 20 grams, Fructus Sorbi Alnifoliae 18 grams, Herba Ardisiae Pusillae 12 grams, Rhizoma Gymnadeniae 15 grams, Herba corchori acutanguli 15 grams, Herba Polygoni Perfoliati 15 grams, 5 grams, Radix Glycyrrhizae, add 8 times of water gagings, decoct 1.5 hours, filter, filtering residue adds 6 times of water gagings, decocts 1 hour, filters, merging filtrate, concentrated, dry, granulate according to this area common process, packaging, must meet the granule of adult normal's 1 day consumption.
Be used for the treatment of secondary thrombocythemia.Oral, every bu is taken for early, middle and late three times.

Claims (1)

1. treat the Chinese medicine of secondary thrombocythemia for one kind, it is characterized in that being made up of the medical material of following weight proportion: Radix cynanchi wallichii 20 parts, Radix Ilicis Cornutae 15 parts, Fructus Rubi 18 parts, money joins 20 parts, Rhizoma Polygonati Cirrhifolii 12 parts, Cold boiled chicken gizzard 15 parts, Radix Cynanchi Atrati 12 parts, Herba Camptosori Sibirici 15 parts, Chinese fanpalm seed 20 parts, Galium spurium L. 12 parts, light dish 15 parts, Eugenia javanica Lam 12 parts, Ligustrum groffiae Merr. 12 parts, Radix seu Folium Rubi Pinfaensis 15 parts, band leaf Flos Primulae Vittatae 15 parts, Resina Liquidambaris 15 parts, 15 parts, Cortex Seu Folium Actinodaphnes Pilosae leaf, Radix Maydis 18 parts, expectorant medicine 12 parts, Eucheuma gelatinosum 12 parts, Os Hydropotes inermis 20 parts, Fructus Sorbi Alnifoliae 18 parts, Herba Ardisiae Pusillae 12 parts, Rhizoma Gymnadeniae 15 parts, Herba corchori acutanguli 15 parts, Herba Polygoni Perfoliati 15 parts, 5 parts, Radix Glycyrrhizae.
CN201410687974.1A 2014-11-26 2014-11-26 Traditional Chinese drug for treating secondary thrombocytosis Pending CN104435833A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110107099A (en) * 2010-03-24 2011-09-30 경희대학교 산학협력단 Composition of herb medicine containing kmkkt extract for preventing or treating cytopenia
CN103610684A (en) * 2013-11-07 2014-03-05 苏州大学 Application of saccharides in preparing medicine for treating platelet quantity related diseases

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20110107099A (en) * 2010-03-24 2011-09-30 경희대학교 산학협력단 Composition of herb medicine containing kmkkt extract for preventing or treating cytopenia
CN103610684A (en) * 2013-11-07 2014-03-05 苏州大学 Application of saccharides in preparing medicine for treating platelet quantity related diseases

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李静等: "王烈教授治疗小儿继发性血小板增多症经验", 《中国中西医结合儿科学》 *

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Application publication date: 20150325