CN104435784A - Traditional Chinese medicine preparation for treating neurasthenia and preparation method and application thereof - Google Patents
Traditional Chinese medicine preparation for treating neurasthenia and preparation method and application thereof Download PDFInfo
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- CN104435784A CN104435784A CN201410791180.XA CN201410791180A CN104435784A CN 104435784 A CN104435784 A CN 104435784A CN 201410791180 A CN201410791180 A CN 201410791180A CN 104435784 A CN104435784 A CN 104435784A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/586—Turtles; Tortoises, e.g. terrapins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/69—Polygalaceae (Milkwort family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8988—Gastrodia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
Abstract
The invention discloses a traditional Chinese medicine preparation for treating neurasthenia. The traditional Chinese medicine preparation respectively comprises the following components by mass: 15-20g of polygonum multiflorum, 3-5g of gastrodia elata, 10-15g of poria cocos, 5-10g of polygala tenuifolia, 10-15g of cortex albiziae, 15-20g of tuber fleeceflower stem, 10-15g of eclipta, 15-20g of tortoise shell and 5-10g of the root of red-rooted salvia. The invention also discloses a preparation method and application of the traditional Chinese medicine preparation. According to the medicinal values of the various components in the traditional Chinese medicine preparation and the compatibility of all the medicines, the traditional Chinese medicine preparation can achieve the effects of effectively tonifying kidneys, calming the heart, clearing heat, soothing the nerves, calming the liver and relieving depression and has the advantages of good curative effect, low cost and no toxic or side effect.
Description
Technical field
The present invention relates to a kind of Chinese medicine preparation and preparation method thereof and application, especially one treats neurasthenic Chinese medicine preparation and preparation method thereof and application, belongs to Chinese medicine formula and applied technical field.
Background technology
Because the modern life, operating pressure are large, a lot of people has neurasthenic problem, often shows as and can not fall asleep night, cause insomnia, daytime absentminded, fatigue and asthenia, hypomnesis, to such an extent as to body system gets muddled.Current therapeutic modality mostly is takes Western medicine, and Western medicine cannot accomplish treating both the principal and secondary aspects of a disease, and toxic and side effects is large, and long-term taking patient easily produces medicine and relies on, and can cause further injury by health.
Summary of the invention
In order to solve the problem, the object of the present invention is to provide that a kind of side effect is little, good effect, expense are low, therapeutic effect is significantly used for the treatment of neurasthenic Chinese medicine preparation and preparation method thereof and application.
For solving the problems of the technologies described above, technical scheme of the present invention is:
Be used for the treatment of neurasthenic Chinese medicine preparation, it is characterized in that, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively:
Radix Polygoni Multiflori: 15-20g;
Rhizoma Gastrodiae: 3-5g;
Poria: 10-15g;
Radix Polygalae: 5-10g;
Cortex Albiziae: 10-15g;
Caulis Polygoni Multiflori: 15-20g;
Herba Ecliptae: 10-15g;
Carapax Et Plastrum Testudinis: 15-20g;
Radix Salviae Miltiorrhizae: 5-10g.
Preferably, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively: Radix Polygoni Multiflori: 18g; Rhizoma Gastrodiae: 4g; Poria: 12g; Radix Polygalae: 8g; Cortex Albiziae: 12g; Caulis Polygoni Multiflori: 18g; Herba Ecliptae: 12g; Carapax Et Plastrum Testudinis: 18g; Radix Salviae Miltiorrhizae: 8g.
Further, above-mentioned is used for the treatment of neurasthenic Chinese medicine preparation, also comprises Rhizoma Chuanxiong 5-10g.
Preferably, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively: Radix Polygoni Multiflori: 18g; Rhizoma Gastrodiae: 4g; Poria: 12g; Radix Polygalae: 8g; Cortex Albiziae: 12g; Caulis Polygoni Multiflori: 18g; Herba Ecliptae: 12g; Carapax Et Plastrum Testudinis: 18g; Radix Salviae Miltiorrhizae: 8g; Rhizoma Chuanxiong 8g.
The above-mentioned manufacture method being used for the treatment of neurasthenic Chinese medicine preparation, is characterized in that, the described each component in neurasthenic Chinese medicine preparation that is used for the treatment of according to after the quality proportioning mixing of every agent, after decocting with water 1.5-2h, is filtered, gets filtrate taking.
And, the application of above-mentioned Chinese medicine preparation on preparation treatment neurasthenia medicine.
Beneficial effect of the present invention is: the present invention is by the medical value of each component in Chinese medicine preparation, and compatibility effect each other, can effectively kidney calming, heat clearing and tranquillizing, suppressing the hyperactive liver resolving depression, there is the advantage that good effect, cost are low, have no side effect.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be described in detail.
As follows for the pharmacology analysis situation of component in Chinese medicine preparation of the present invention:
Fang Zhong:
Radix Polygoni Multiflori 15-20g: slightly warm in nature, bitter in the mouth, sweet, puckery, return liver, the heart, kidney channel, there is invigorating the liver and kidney, effect that benefiting essence-blood, nourishing the blood and yin are calmed the nerves.
Rhizoma Gastrodiae 3-5g: Rhizoma Gastrodiae is put down, and sweet in the mouth, has effect of suppressing the hyperactive liver relieving convulsion, dispelling wind and removing obstruction in the collateral, and the symptom such as dizziness headache, vexed irritability especially caused for neurasthenia has good therapeutic effect;
Poria 10-15g: property is put down, sweet in the mouth, light, has effect of diuretic spleen invigorating, mind tranquilizing and the heart calming;
Radix Polygalae 5-10g: slightly warm in nature, bitter in the mouth, pungent, having eliminates the phlegm has one's ideas straightened out, effect of mind tranquilizing and the heart calming;
Cortex Albiziae 10-15g: property is put down, and sweet in the mouth, has effect of promoting blood circulation and detumescence, resolving stagnation for tranquilization;
Caulis Polygoni Multiflori: 15-20g: property is put down, and sweet in the mouth, has effect of dispelling wind and removing obstruction in the collateral, tranquilizing by nourishing the heart;
Herba Ecliptae 10-15g: cool in nature, sweet in the mouth, acid, have effect of nourishing the liver and kidney, cooling blood for hemostasis, especially has significant curative effect to liver-kidney yin deficiency neurasthenia;
Carapax Et Plastrum Testudinis 15-20g: cold nature, sweet in the mouth, salty, there is effect of nourishing YIN for suppressing the hyperactive YANG, reinforcing the kidney to strengthen the bone, reinforcing the heart of nourishing blood, controlling nocturnal emission with astringent drugs hemostasis;
Radix Salviae Miltiorrhizae 5-10g: cold nature, bitter in the mouth, has effect of blood circulation promoting and blood stasis dispelling, nourishing blood to tranquillize the mind, menstruction regulating and pain relieving, removing heat from blood eliminating carbuncle;
Rhizoma Chuanxiong 5-10g: warm in nature, acrid in the mouth, has effect of blood-activating and qi-promoting, wind-expelling pain-stopping, is applicable to qi stagnation and blood stasis type, liver qi stagnation type neurastheniac, headache and dizzy, hypochondriac pain that effectively relieving neurasthenia causes can make the symptoms such as swollen, improve the emotions such as depression, fluctuation.
Above all medicines share then can effectively kidney calming, heat clearing and tranquillizing, suppressing the hyperactive liver resolving depression, to treatment, neurasthenia has significant curative effect, especially effectively can improve excessive thinking, lassitude, feel dizzy, dreaminess, the disease such as palpitation and amnesia.
embodiment 1:
The component be used for the treatment of in neurasthenic Chinese medicine preparation by described: Radix Polygoni Multiflori: 20g; Rhizoma Gastrodiae: 5g; Poria: 15g; Radix Polygalae: 10g; Cortex Albiziae: 10g; Caulis Polygoni Multiflori: 15g; Herba Ecliptae: 10g; Carapax Et Plastrum Testudinis: 20g; After Radix Salviae Miltiorrhizae: 10g mixes, after decocting with water 1.5h, filter, get filtrate taking, every day 1 dose, before morning, supper, half an hour takes at twice, 7 days each courses for the treatment of, takes 4 courses for the treatment of.
embodiment 2:
The component be used for the treatment of in neurasthenic Chinese medicine preparation by described: Radix Polygoni Multiflori: 15g; Rhizoma Gastrodiae: 3g; Poria: 10g; Radix Polygalae: 5g; Cortex Albiziae: 15g; Caulis Polygoni Multiflori: 20g; Herba Ecliptae: 15g; Carapax Et Plastrum Testudinis: 15g; After Radix Salviae Miltiorrhizae: 5g mixes, after decocting with water 2h, filter, get filtrate taking, every day 1 dose, before morning, supper, half an hour takes at twice, 7 days each courses for the treatment of, takes 4 courses for the treatment of.
embodiment 3:
The component be used for the treatment of in neurasthenic Chinese medicine preparation by described: Radix Polygoni Multiflori: 18g; Rhizoma Gastrodiae: 4g; Poria: 12g; Radix Polygalae: 8g; Cortex Albiziae: 12g; Caulis Polygoni Multiflori: 18g; Herba Ecliptae: 12g; Carapax Et Plastrum Testudinis: 18g; After Radix Salviae Miltiorrhizae: 8g mixes, after decocting with water 1.8h, filter, get filtrate taking, every day 1 dose, before morning, supper, half an hour takes at twice, 7 days each courses for the treatment of, takes 4 courses for the treatment of.
embodiment 4:
The component be used for the treatment of in neurasthenic Chinese medicine preparation by described: Radix Polygoni Multiflori: 20g; Rhizoma Gastrodiae: 3g; Poria: 15g; Radix Polygalae: 5g; Cortex Albiziae: 10g; Caulis Polygoni Multiflori: 20g; Herba Ecliptae: 10g; Carapax Et Plastrum Testudinis: 20g; Radix Salviae Miltiorrhizae: 5g; After Rhizoma Chuanxiong 5g mixes, after decocting with water 1.5h, filter, get filtrate taking, every day 1 dose, before morning, supper, half an hour takes at twice, 7 days each courses for the treatment of, takes 4 courses for the treatment of.
embodiment 5:
The component be used for the treatment of in neurasthenic Chinese medicine preparation by described: Radix Polygoni Multiflori: 18g; Rhizoma Gastrodiae: 4g; Poria: 12g; Radix Polygalae: 8g; Cortex Albiziae: 12g; Caulis Polygoni Multiflori: 18g; Herba Ecliptae: 12g; Carapax Et Plastrum Testudinis: 18g; Radix Salviae Miltiorrhizae: 8g; After Rhizoma Chuanxiong 8g mixes, after decocting with water 2h, filter, get filtrate taking, every day 1 dose, before morning, supper, half an hour takes at twice, 7 days each courses for the treatment of, takes 4 courses for the treatment of.
For verifying the clinical effectiveness of invention formulation, carry out clinical experiment.
1, case selection standard:
A, main suit's sleep quality is not good enough, difficulty of falling asleep;
B, there is the symptoms such as fatigue and weak on daytime, absentminded, giddy, hypomnesis.
2, diagnostic criteria
(1) or after requiring mental skill tired continuing and the main suit of misery is felt more; Or be slightly firmly rear physical weakness and tired the continuing and the main suit of misery of extreme;
(2) at least following two are had: 1. myalgia pain; 2. dizzy; 3. tension headache; 4. sleep disordered; 5. can not loosen; 6. irritability: 7. dyspepsia;
(3) any and the autonomic nerve symptom of depositing or depressive symptom, at severity be not enough in the persistent period meet other obstacle standards.
3, therapeutic scheme
Treatment group 48 example, man 26 example, female 22 example, maximum 50 years old, minimum 25 years old ,-3 years Mays of the course of disease were not etc., take the Chinese medicine preparation described in the embodiment of the present invention 3, every day potion, every day twice, it within 7 days, is a course for the treatment of, take 4 courses for the treatment of, matched group 46 example, man 29 example, female 17 example, maximum 46 years old, minimum 25 years old ,-2 years April of the course of disease was not etc., take estazolam 2mg, decoction being taken at a draught every night 7 days is a course for the treatment of, takes 4 courses for the treatment of, through statistical analysis, two groups of case-data there was no significant differences (P<0.05).
4, the course for the treatment of evaluation criteria:
Effective: symptom disappears substantially;
Effective: cardinal symptom disappears;
Invalid: before symptom and treatment, not have any improvement.
5, therapeutic effect:
Specifically in table 1.
Table 1 therapeutic effect compares
| Group | Number of cases | Effective | Effectively | Invalid | Total effective rate (%) |
| Treatment group | 48 | 15 | 30 | 3 | 93.8 |
| Matched group | 46 | 8 | 19 | 19 | 58.7 |
The present invention is by the medical value of each component in Chinese medicine preparation, and compatibility effect each other, can effectively kidney calming, heat clearing and tranquillizing, suppressing the hyperactive liver resolving depression, there is the advantage that good effect, cost are low, have no side effect.
Above detailed description of the invention does not limit the present invention in any form, and every technical scheme obtained in the mode of equivalent replacement or equivalent transformation, all drops in protection scope of the present invention.
Claims (6)
1. be used for the treatment of neurasthenic Chinese medicine preparation, it is characterized in that, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively:
Radix Polygoni Multiflori: 15-20g;
Rhizoma Gastrodiae: 3-5g;
Poria: 10-15g;
Radix Polygalae: 5-10g;
Cortex Albiziae: 10-15g;
Caulis Polygoni Multiflori: 15-20g;
Herba Ecliptae: 10-15g;
Carapax Et Plastrum Testudinis: 15-20g;
Radix Salviae Miltiorrhizae: 5-10g.
2. be according to claim 1ly used for the treatment of neurasthenic Chinese medicine preparation, it is characterized in that, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively: Radix Polygoni Multiflori: 18g; Rhizoma Gastrodiae: 4g; Poria: 12g; Radix Polygalae: 8g; Cortex Albiziae: 12g; Caulis Polygoni Multiflori: 18g; Herba Ecliptae: 12g; Carapax Et Plastrum Testudinis: 18g; Radix Salviae Miltiorrhizae: 8g.
3. be according to claim 1ly used for the treatment of neurasthenic Chinese medicine preparation, it is characterized in that, also comprise Rhizoma Chuanxiong 5-10g.
4. be according to claim 3ly used for the treatment of neurasthenic Chinese medicine preparation, it is characterized in that, the formula composition of every agent Chinese medicine preparation comprises following component and the quality of each component is respectively: Radix Polygoni Multiflori: 18g; Rhizoma Gastrodiae: 4g; Poria: 12g; Radix Polygalae: 8g; Cortex Albiziae: 12g; Caulis Polygoni Multiflori: 18g; Herba Ecliptae: 12g; Carapax Et Plastrum Testudinis: 18g; Radix Salviae Miltiorrhizae: 8g; Rhizoma Chuanxiong 8g.
5. the manufacture method being used for the treatment of neurasthenic Chinese medicine preparation according to claim 1, it is characterized in that, after by described being used for the treatment of, in neurasthenic Chinese medicine preparation, each component mixes according to the quality proportioning of every agent, after decocting with water 1.5-2h, filter, get filtrate taking.
6. the application of Chinese medicine preparation according to claim 5 on preparation treatment neurasthenia medicine.
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| CN201410791180.XA CN104435784A (en) | 2014-12-19 | 2014-12-19 | Traditional Chinese medicine preparation for treating neurasthenia and preparation method and application thereof |
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| CN201410791180.XA CN104435784A (en) | 2014-12-19 | 2014-12-19 | Traditional Chinese medicine preparation for treating neurasthenia and preparation method and application thereof |
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| CN104435784A true CN104435784A (en) | 2015-03-25 |
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005060357A (en) * | 2003-08-12 | 2005-03-10 | ▲張▼ ▲書▼廷 | Health food for promoting sleep and tranquirizing by using plant as raw material and method for producing the same |
| CN104173767A (en) * | 2014-08-19 | 2014-12-03 | 金先琦 | Traditional Chinese medicine capsule for treating neurasthenia |
-
2014
- 2014-12-19 CN CN201410791180.XA patent/CN104435784A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2005060357A (en) * | 2003-08-12 | 2005-03-10 | ▲張▼ ▲書▼廷 | Health food for promoting sleep and tranquirizing by using plant as raw material and method for producing the same |
| CN104173767A (en) * | 2014-08-19 | 2014-12-03 | 金先琦 | Traditional Chinese medicine capsule for treating neurasthenia |
Non-Patent Citations (3)
| Title |
|---|
| 杨卫平等: "《新编中草药图谱及经典配方1》", 31 May 2014 * |
| 王丽: "《中药配伍手册》", 30 June 2013 * |
| 苑振亭: "《新编中药400味速查手册》", 30 September 2014 * |
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