CN104434037A - Modified SD - OCT system based on multi-channel spectrometer - Google Patents
Modified SD - OCT system based on multi-channel spectrometer Download PDFInfo
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- CN104434037A CN104434037A CN201410770446.2A CN201410770446A CN104434037A CN 104434037 A CN104434037 A CN 104434037A CN 201410770446 A CN201410770446 A CN 201410770446A CN 104434037 A CN104434037 A CN 104434037A
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- channel spectrometer
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
- A61B5/0062—Arrangements for scanning
- A61B5/0066—Optical coherence imaging
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Abstract
The invention discloses a modified SD - OCT system based on a multi-channel spectrometer and belongs to medical imaging equipment field. The system comprises a broadband light source, a reference arm, a sample arm, a multi-channel spectrometer and a computer module. A wavelength division multiplexer installed inside the multi-channel spectrometer decomposes the interference light into many light signals of different wavelengths. The light spectrum of each light signal is received by the array CCD arranged inside the multi-channel spectrometer at the same time. The received spectral width is added, axial resolution of the system is increased, the mechanical scanning noise of the liner CCD is also avoided, and imaging speed and quality of the system is improved.
Description
Technical field
The present invention relates to medical imaging instruments industry, be specifically related to a kind of modified model SD-OCT system based on multi-channel spectrometer based.
Background technology
In human health Diagnosis and Treat field, biomedical imaging technology is one of medical diagnosis most important method the most directly perceived.Relative to traditional imaging technique, spectral domain optical coherent tomographic (Spectral DomainOptical Coherence Tomography, SD-OCT) system have high-resolution, hurtless measure, fast, the significant advantage such as live body real-time.Along with the progress of science and technology and the expansion of application, SD-OCT system is just towards image taking speed and higher image quality develop faster.The axial resolution of SD-OCT system is directly proportional to detectable spectral width, and the spectrum acquisition widths affect therefore in SD-OCT system the resolution of system, the spectrum acquisition time effects system imaging time.
At present, the spectral information receiving system in SD-OCT system generally uses single channel spectrogrph.The spectral width that the drawback that single channel spectrogrph exists in SD-OCT system mainly receives is limited by the size of line array CCD, therefore system axial resolution limitations system.To receive wider spectral region, needing line array CCD to carry out mechanical scanning, so just limiting the image taking speed of system, the vibrations simultaneously scanning generation can introduce more noises to signal, affect image quality.
The present invention designs to use and adopts area array CCD can increase detecting light spectrum width as the multi-channel spectrometer based of Signal reception device in SD-OCT system, thus improves system axial resolution.In addition, because interference signal can be decomposed into the optical signal of different wave length by wavelength division multiplexer, multi-channel spectrometer based can accept multiple signals simultaneously, with the use of the image taking speed that can improve system.
Summary of the invention
In order to overcome above-mentioned traditional SD-OCT intersystem problem, the invention provides a kind of modified model SD-OCT system based on multi-channel spectrometer based, the described modified model SD-OCT system based on multi-channel spectrometer based effectively can break through the restriction of line array CCD size, expand receiving spectrum scope, improve system axial resolution.And area array CCD is without the need to scanning, receives multiple signals, improves image taking speed and quality simultaneously.
For reaching above-mentioned purpose, the technical solution used in the present invention is: with plurality of LEDs light sources synthesis wideband light source, obtain the light source that bandwidth is wider, and design multi-channel spectrometer based instead of traditional single channel spectrogrph in systems in which.Add wavelength division multiplexer in the optical path, the interference light with sample depth information is resolved into the different optical signal of multichannel wavelength by wavelength division multiplexer.By the output channel parallel arranged of wavelength division multiplexer, these passages are equivalent to the slit of spectrogrph.After wavelength division multiplexer, adopt transmission-type grating as the beam splitter of spectrogrph, every road signal all can obtain corresponding spectral signal through grating.Area array CCD selected by spectrographic detection element, and the row of spectrum respectively corresponding to area array CCD of each road optical signal synchronously receive to pixel, finally signal are inputted computer and carry out inverse fourier transform, obtain sample interior information.
Compared with prior art, beneficial effect of the present invention is:
(1) the present invention adopts multi-channel spectrometer based to replace conventional one-channel spectrogrph, effectively breaks through the restriction of CCD size, expands receiving spectrum scope, improve systemic resolution.
(2) a kind of modified model SD-OCT system based on multi-channel spectrometer based of the present invention, adopts multi-channel spectrometer based, and its area array CCD, without the need to scanning, can receive multiple signals simultaneously, improve image taking speed and quality.
Below in conjunction with accompanying drawing and detailed description of the invention, the present invention is described further.
Accompanying drawing explanation
Fig. 1 is the described modified model SD-OCT system architecture diagram based on multi-channel spectrometer based.
Fig. 2 is the described modified model SD-OCT systematic schematic diagram based on multi-channel spectrometer based.
1. wideband light sources, 2. bonder, 3. wavelength division multiplexer, 4. transmission grating, 5. area array CCD, 6. computer, 7. plane mirror, 8. sample, 9. reference arm, 10. sample arm in figure, 11. multi-channel spectrometer baseds.
Detailed description of the invention
Below in conjunction with accompanying drawing, the invention will be further described.
As shown in Figure 1, the present invention mainly includes wideband light source (1), reference arm (9), sample arm (10), multi-channel spectrometer based (11), computer (6) five modules.System Working Principle is as follows: in Fig. 2, light source (1) is by the hybrid light source of plurality of LEDs combination of light sources, the broadband light sent is divided into two-way through 50:50 bonder (2), enters described reference arm (9) and sample arm (10) respectively.Two-way light reflects second time through plane mirror (7) and sample (8) respectively and enters bonder (2), and interferes.Interference light containing sample depth information resolves into the optical signal of different wave length through described wavelength division multiplexer (3), the transmission-type grating of light after wavelength division multiplexer (4) diffraction light splitting produces corresponding spectrum, the spectral information of every road optical signal is received by the pixel row that area array CCD (5) is corresponding, last and computer (6) of information being passed on a skill of craft to others, obtains sample faultage image through image reconstruction.
Claims (4)
1. the modified model SD-OCT system based on multi-channel spectrometer based, be made up of wideband light source, reference arm, sample arm, spectrogrph, computer, it is characterized in that: wideband light source is hybrid light source, and the interference light containing sample depth information obtains spectral information through multi-channel spectrometer based.
2. as claimed in claim 1 based on the modified model SD-OCT system of multi-channel spectrometer based, it is characterized in that: mixing wideband light source is combined by plurality of LEDs lamp, obtains the light source that bandwidth is wider.
3., as claimed in claim 1 based on the modified model SD-OCT system of multi-channel spectrometer based, it is characterized in that: wavelength division multiplexer output channel is equivalent to the slit of described multi-channel spectrometer based, interference light is broken down into the optical signal of multichannel different wave length.
4. as claimed in claim 1 based on the modified model SD-OCT system of multi-channel spectrometer based, it is characterized in that: described multi-channel spectrometer based spectral signal receiving device adopts area array CCD, avoids line array CCD mechanical scanning, receive multi-path light spectrum signal simultaneously.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410770446.2A CN104434037A (en) | 2014-12-12 | 2014-12-12 | Modified SD - OCT system based on multi-channel spectrometer |
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| CN201410770446.2A CN104434037A (en) | 2014-12-12 | 2014-12-12 | Modified SD - OCT system based on multi-channel spectrometer |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108514404A (en) * | 2018-03-28 | 2018-09-11 | 深圳市太赫兹科技创新研究院 | Optical coherence tomography system |
| CN110367941A (en) * | 2019-08-20 | 2019-10-25 | 东北大学秦皇岛分校 | A kind of detection light fusion Noncontact optoacoustic-optical coherence tomography double-mode imaging system |
| CN110477852A (en) * | 2019-08-02 | 2019-11-22 | 佛山科学技术学院 | A kind of iris vessels imaging system |
| CN110575142A (en) * | 2019-09-16 | 2019-12-17 | 南京波斯泰克光电科技有限公司 | Multi-beam optical coherence tomography instrument of single spectrometer |
| CN110686707A (en) * | 2019-09-06 | 2020-01-14 | 天津大学 | Multichannel polarization low-coherence interference demodulation system and demodulation method based on area array CCD |
| CN111044947A (en) * | 2019-12-24 | 2020-04-21 | 北京航天控制仪器研究所 | Multichannel SERF atomic magnetometer device for magnetoencephalography and application method |
| CN114217379A (en) * | 2021-12-14 | 2022-03-22 | 湖南卡睿知医疗科技有限公司 | Special optical fiber module and system for OCT |
| WO2024084295A1 (en) * | 2022-10-19 | 2024-04-25 | Ap Infosense Limited | Optical integrated chip and high resolution low-cost integrated handheld miniature spectrometer |
-
2014
- 2014-12-12 CN CN201410770446.2A patent/CN104434037A/en active Pending
Cited By (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108514404A (en) * | 2018-03-28 | 2018-09-11 | 深圳市太赫兹科技创新研究院 | Optical coherence tomography system |
| CN110477852A (en) * | 2019-08-02 | 2019-11-22 | 佛山科学技术学院 | A kind of iris vessels imaging system |
| CN110367941A (en) * | 2019-08-20 | 2019-10-25 | 东北大学秦皇岛分校 | A kind of detection light fusion Noncontact optoacoustic-optical coherence tomography double-mode imaging system |
| CN110367941B (en) * | 2019-08-20 | 2022-01-28 | 东北大学秦皇岛分校 | Detection light fusion non-contact photoacoustic-optical coherence tomography dual-mode imaging system |
| CN110686707A (en) * | 2019-09-06 | 2020-01-14 | 天津大学 | Multichannel polarization low-coherence interference demodulation system and demodulation method based on area array CCD |
| CN110575142A (en) * | 2019-09-16 | 2019-12-17 | 南京波斯泰克光电科技有限公司 | Multi-beam optical coherence tomography instrument of single spectrometer |
| CN111044947A (en) * | 2019-12-24 | 2020-04-21 | 北京航天控制仪器研究所 | Multichannel SERF atomic magnetometer device for magnetoencephalography and application method |
| CN111044947B (en) * | 2019-12-24 | 2022-05-24 | 北京航天控制仪器研究所 | Multichannel SERF atomic magnetometer device for magnetoencephalography and application method |
| CN114217379A (en) * | 2021-12-14 | 2022-03-22 | 湖南卡睿知医疗科技有限公司 | Special optical fiber module and system for OCT |
| CN114217379B (en) * | 2021-12-14 | 2022-07-26 | 湖南卡睿知医疗科技有限公司 | Optical fiber module and system special for OCT (optical coherence tomography) |
| WO2024084295A1 (en) * | 2022-10-19 | 2024-04-25 | Ap Infosense Limited | Optical integrated chip and high resolution low-cost integrated handheld miniature spectrometer |
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Application publication date: 20150325 |