WO2006116672A3 - Systems and methods for tomographic image reconstruction - Google Patents

Systems and methods for tomographic image reconstruction Download PDF

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Publication number
WO2006116672A3
WO2006116672A3 PCT/US2006/016210 US2006016210W WO2006116672A3 WO 2006116672 A3 WO2006116672 A3 WO 2006116672A3 US 2006016210 W US2006016210 W US 2006016210W WO 2006116672 A3 WO2006116672 A3 WO 2006116672A3
Authority
WO
WIPO (PCT)
Prior art keywords
systems
light
mammalian tissue
methods
tomographic image
Prior art date
Application number
PCT/US2006/016210
Other languages
French (fr)
Other versions
WO2006116672A2 (en
Inventor
Brian William Pogue
Daqing Piao
Keith D Paulsen
Shudong Jiang
Hamid Dehghani
Heng Xu
Roger Springett
Subha Srinivasan
Original Assignee
Dartmouth College
Brian William Pogue
Daqing Piao
Keith D Paulsen
Shudong Jiang
Hamid Dehghani
Heng Xu
Roger Springett
Subha Srinivasan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US11/115,865 external-priority patent/US7962198B2/en
Application filed by Dartmouth College, Brian William Pogue, Daqing Piao, Keith D Paulsen, Shudong Jiang, Hamid Dehghani, Heng Xu, Roger Springett, Subha Srinivasan filed Critical Dartmouth College
Priority to US12/088,845 priority Critical patent/US8000775B2/en
Publication of WO2006116672A2 publication Critical patent/WO2006116672A2/en
Publication of WO2006116672A3 publication Critical patent/WO2006116672A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0062—Arrangements for scanning
    • A61B5/0066—Optical coherence imaging
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0082—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes
    • A61B5/0091—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence adapted for particular medical purposes for mammography
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/43—Detecting, measuring or recording for evaluating the reproductive systems
    • A61B5/4306—Detecting, measuring or recording for evaluating the reproductive systems for evaluating the female reproductive systems, e.g. gynaecological evaluations
    • A61B5/4312—Breast evaluation or disorder diagnosis
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0218—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/0205—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows
    • G01J3/0218—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers
    • G01J3/0221—Optical elements not provided otherwise, e.g. optical manifolds, diffusers, windows using optical fibers the fibers defining an entry slit
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/02—Details
    • G01J3/10—Arrangements of light sources specially adapted for spectrometry or colorimetry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01J—MEASUREMENT OF INTENSITY, VELOCITY, SPECTRAL CONTENT, POLARISATION, PHASE OR PULSE CHARACTERISTICS OF INFRARED, VISIBLE OR ULTRAVIOLET LIGHT; COLORIMETRY; RADIATION PYROMETRY
    • G01J3/00—Spectrometry; Spectrophotometry; Monochromators; Measuring colours
    • G01J3/28—Investigating the spectrum
    • G01J3/2803—Investigating the spectrum using photoelectric array detector
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/72—Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235—Details of waveform analysis
    • A61B5/7239—Details of waveform analysis using differentiation including higher order derivatives
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N2021/178—Methods for obtaining spatial resolution of the property being measured
    • G01N2021/1785—Three dimensional
    • G01N2021/1787—Tomographic, i.e. computerised reconstruction from projective measurements

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biophysics (AREA)
  • Biomedical Technology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Reproductive Health (AREA)
  • Radiology & Medical Imaging (AREA)

Abstract

Optical tomography systems that provide light of multiple distinct wavelengths from a plurality of sources are described. The systems direct light into mammalian tissue, and light from the mammalian tissue is collected at a plurality of reception points. Collected light from each reception point is separated according to its wavelength, and received by a photodetector to produce path attenuation signals representing attenuation along paths between the source locations and the reception points. An image construction system generates a tomographic image of the mammalian tissue from the path attenuation signals. One embodiment of an optical imaging system includes an optical coherence tomography-near infrared probe. The systems and methods may utilize a spectral derivative approach that provides insensitivity to the boundary and boundary artifacts in the signal, thereby improving the quality of the reconstructed images.
PCT/US2006/016210 2005-04-27 2006-04-27 Systems and methods for tomographic image reconstruction WO2006116672A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US12/088,845 US8000775B2 (en) 2005-04-27 2006-04-27 Systems and methods for tomographic image reconstruction

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US11/115,865 2005-04-27
US11/115,865 US7962198B2 (en) 2005-04-27 2005-04-27 System and method for spectral-encoded high-rate hemodynamic tomography
US68972705P 2005-06-10 2005-06-10
US60/689,727 2005-06-10

Publications (2)

Publication Number Publication Date
WO2006116672A2 WO2006116672A2 (en) 2006-11-02
WO2006116672A3 true WO2006116672A3 (en) 2007-02-22

Family

ID=36763226

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2006/016210 WO2006116672A2 (en) 2005-04-27 2006-04-27 Systems and methods for tomographic image reconstruction

Country Status (1)

Country Link
WO (1) WO2006116672A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7357385B2 (en) 2018-10-15 2023-10-06 キョンブク ナショナル ユニヴァーシティ インダストリー－アカデミック コオペレーション ファウンデーション Optical coherence tomography device and image generation method using the same

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US8017927B2 (en) 2005-12-16 2011-09-13 Honeywell International Inc. Apparatus, system, and method for print quality measurements using multiple adjustable sensors
US7688447B2 (en) 2005-12-29 2010-03-30 Honeywell International Inc. Color sensor
US7880156B2 (en) 2006-12-27 2011-02-01 Honeywell International Inc. System and method for z-structure measurements using simultaneous multi-band tomography
WO2009077953A1 (en) * 2007-12-17 2009-06-25 Koninklijke Philips Electronics N.V. Method for reconstructing an image of an interior of a turbid medium and device for imaging the interior of turbid media
US8401809B2 (en) 2010-07-12 2013-03-19 Honeywell International Inc. System and method for adjusting an on-line appearance sensor system
US8618929B2 (en) 2011-05-09 2013-12-31 Honeywell International Inc. Wireless conveyor belt condition monitoring system and related apparatus and method
JP6813245B2 (en) 2014-10-14 2021-01-13 イースト カロライナ ユニバーシティ How to operate a system to combine anatomical and physiological data on a single image, a computer system, and a program to combine anatomical and physiological data on a single image. Recording medium on which
CA2963866C (en) 2014-10-14 2023-11-07 East Carolina University Methods, systems and computer program products for determining hemodynamic status parameters using signals derived from multispectral blood flow and perfusion imaging
US11553844B2 (en) 2014-10-14 2023-01-17 East Carolina University Methods, systems and computer program products for calculating MetaKG signals for regions having multiple sets of optical characteristics
US10058256B2 (en) 2015-03-20 2018-08-28 East Carolina University Multi-spectral laser imaging (MSLI) methods and systems for blood flow and perfusion imaging and quantification
US10390718B2 (en) 2015-03-20 2019-08-27 East Carolina University Multi-spectral physiologic visualization (MSPV) using laser imaging methods and systems for blood flow and perfusion imaging and quantification in an endoscopic design
CN107894204B (en) 2016-10-04 2020-02-21 财团法人工业技术研究院 Interferometer and imaging method thereof
WO2018076004A1 (en) * 2016-10-23 2018-04-26 Doseoptics Llc Advanced cherenkov-based imaging systems, tools, and methods of feedback control, temporal control sequence image capture, and quantification in high resolution dose images
US10832074B2 (en) 2019-03-08 2020-11-10 International Business Machines Corporation Uncertainty region based image enhancement
CN112330708B (en) * 2020-11-24 2024-04-23 沈阳东软智能医疗科技研究院有限公司 Image processing method, device, storage medium and electronic equipment

Citations (4)

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Publication number Priority date Publication date Assignee Title
US5349954A (en) * 1993-07-23 1994-09-27 General Electric Company Tumor tissue characterization apparatus and method
US5722407A (en) * 1993-09-08 1998-03-03 Siemens Aktiengesellschaft Apparatus and method for examining tissue with light of different wavelengths
WO2003012391A2 (en) * 2001-07-27 2003-02-13 The Regents Of The University Of California Broadband absorption spectroscopy in turbid media by combined frequency-domain and steady state methodologies
US20030085338A1 (en) * 2001-07-16 2003-05-08 David Hall Simultaneous multiwavelength TPSF-based optical imaging

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5349954A (en) * 1993-07-23 1994-09-27 General Electric Company Tumor tissue characterization apparatus and method
US5722407A (en) * 1993-09-08 1998-03-03 Siemens Aktiengesellschaft Apparatus and method for examining tissue with light of different wavelengths
US20030085338A1 (en) * 2001-07-16 2003-05-08 David Hall Simultaneous multiwavelength TPSF-based optical imaging
WO2003012391A2 (en) * 2001-07-27 2003-02-13 The Regents Of The University Of California Broadband absorption spectroscopy in turbid media by combined frequency-domain and steady state methodologies

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7357385B2 (en) 2018-10-15 2023-10-06 キョンブク ナショナル ユニヴァーシティ インダストリー－アカデミック コオペレーション ファウンデーション Optical coherence tomography device and image generation method using the same

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Publication number Publication date
WO2006116672A2 (en) 2006-11-02

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