CN104412160B - 生物活性剂递送装置以及其制备和使用方法 - Google Patents

生物活性剂递送装置以及其制备和使用方法 Download PDF

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Publication number
CN104412160B
CN104412160B CN201380035217.XA CN201380035217A CN104412160B CN 104412160 B CN104412160 B CN 104412160B CN 201380035217 A CN201380035217 A CN 201380035217A CN 104412160 B CN104412160 B CN 104412160B
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CN
China
Prior art keywords
microdevice
poly
drug
microdevices
bioactive agent
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Expired - Fee Related
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CN201380035217.XA
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English (en)
Chinese (zh)
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CN104412160A (zh
Inventor
T·A·德塞
H·D·基拉
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University of California San Diego UCSD
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University of California San Diego UCSD
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Publication of CN104412160A publication Critical patent/CN104412160A/zh
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
    • A61M31/002—Devices for releasing a drug at a continuous and controlled rate for a prolonged period of time
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0097—Medicinal compositions released by microdevices, e.g. microelectromechanical systems [MEMS], microdevices comprising chips or microdevices on silicon
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03F—PHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR
    • G03F7/00—Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printing surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
    • G03F7/0035—Multiple processes, e.g. applying a further resist layer on an already in a previously step, processed pattern or textured surface
    • G—PHYSICS
    • G03—PHOTOGRAPHY; CINEMATOGRAPHY; ANALOGOUS TECHNIQUES USING WAVES OTHER THAN OPTICAL WAVES; ELECTROGRAPHY; HOLOGRAPHY
    • G03F—PHOTOMECHANICAL PRODUCTION OF TEXTURED OR PATTERNED SURFACES, e.g. FOR PRINTING, FOR PROCESSING OF SEMICONDUCTOR DEVICES; MATERIALS THEREFOR; ORIGINALS THEREFOR; APPARATUS SPECIALLY ADAPTED THEREFOR
    • G03F7/00—Photomechanical, e.g. photolithographic, production of textured or patterned surfaces, e.g. printing surfaces; Materials therefor, e.g. comprising photoresists; Apparatus specially adapted therefor
    • G03F7/26—Processing photosensitive materials; Apparatus therefor
    • G03F7/40—Treatment after imagewise removal, e.g. baking

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  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Medicinal Preparation (AREA)
  • Materials For Medical Uses (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN201380035217.XA 2012-05-30 2013-05-24 生物活性剂递送装置以及其制备和使用方法 Expired - Fee Related CN104412160B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201261653119P 2012-05-30 2012-05-30
US61/653,119 2012-05-30
PCT/US2013/042710 WO2013181107A1 (en) 2012-05-30 2013-05-24 Bioactive agent delivery devices and methods of making and using the same

Publications (2)

Publication Number Publication Date
CN104412160A CN104412160A (zh) 2015-03-11
CN104412160B true CN104412160B (zh) 2019-09-20

Family

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CN201380035217.XA Expired - Fee Related CN104412160B (zh) 2012-05-30 2013-05-24 生物活性剂递送装置以及其制备和使用方法

Country Status (8)

Country Link
US (1) US9878137B2 (https=)
EP (1) EP2856259B1 (https=)
JP (1) JP6336442B2 (https=)
CN (1) CN104412160B (https=)
BR (1) BR112014029760A2 (https=)
CA (1) CA2875146C (https=)
IN (1) IN2014DN10765A (https=)
WO (1) WO2013181107A1 (https=)

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PL3574897T3 (pl) 2011-11-18 2022-05-09 Regeneron Pharmaceuticals, Inc. Postać użytkowa o przedłużonym uwalnianiu zawierająca mikrocząstki białka polimerowego do stosowania w ciele szklistym oka w leczeniu naczyniowych zaburzeń oczu
US9463177B2 (en) 2012-09-10 2016-10-11 The Regents Of The University Of California Compounds and methods for modulating vascular injury
MX2016007786A (es) 2013-12-16 2017-03-03 Massachusetts Inst Technology Formulaciones de sal de micronutrientes fortificadas.
AU2014364930B2 (en) 2013-12-16 2017-06-15 Massachusetts Institute Of Technology Micromolded or 3-D printed pulsatile release vaccine formulations
EP3233124B1 (en) * 2014-12-15 2020-11-18 The Regents of The University of California Nanowire-coated microdevice and method of making and using the same
WO2017066554A1 (en) 2015-10-16 2017-04-20 Regeneron Pharmaceuticals, Inc. Stable protein compositions
US10429387B2 (en) * 2016-07-27 2019-10-01 Universiteit Tweate Simple and affordable method for immuophenotyping using a microfluidic chip sample preparation with image cytometry
WO2019055613A1 (en) * 2017-09-13 2019-03-21 Massachusetts Institute Of Technology COMPLEX GEOMETRY MICRODISPOSITIVES
JP7287032B2 (ja) * 2019-03-20 2023-06-06 株式会社リコー シート、シート積層体、医薬品、シートの製造方法、及びシート積層体の製造方法
JP7776145B2 (ja) 2020-05-13 2025-11-26 マサチューセッツ インスティテュート オブ テクノロジー ポリマーマイクロデバイスの組成物およびがん免疫療法におけるその使用
CN113804667A (zh) * 2021-09-23 2021-12-17 上海交通大学 一种新型可膨胀生物样本的水凝胶及其应用
US20240077474A1 (en) * 2022-09-06 2024-03-07 Seagate Technology Llc System and methods for positioning biomaterial on a substrate

Citations (4)

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US5797898A (en) * 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
WO2000041740A2 (en) * 1999-01-11 2000-07-20 The Regents Of The University Of California Particles for oral delivery of peptides and proteins
WO2004006840A2 (en) * 2002-07-12 2004-01-22 The Regents Of The University Of California Three dimensional cell patterned bioploymer scaffolds and method of making the same
US7622081B2 (en) * 2000-06-05 2009-11-24 California Institute Of Technology Integrated active flux microfluidic devices and methods

Family Cites Families (12)

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US5410016A (en) 1990-10-15 1995-04-25 Board Of Regents, The University Of Texas System Photopolymerizable biodegradable hydrogels as tissue contacting materials and controlled-release carriers
JPH11507913A (ja) * 1995-06-07 1999-07-13 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 治療用マイクロデバイスならびにその製造方法および使用方法
US5567271A (en) 1995-07-26 1996-10-22 Chartered Semiconductor Manufacturing Pte Ltd Oxygen reactive ion etch (RIE) plasma method for removing oxidized organic residues from semiconductor substrates
US6391216B1 (en) 1997-09-22 2002-05-21 National Research Institute For Metals Method for reactive ion etching and apparatus therefor
US6770441B2 (en) 2000-02-10 2004-08-03 Illumina, Inc. Array compositions and methods of making same
EP1372602B1 (en) * 2001-01-09 2007-04-18 Microchips, Inc. Flexible microchip devices for ophthalmic and other applications
US20020115224A1 (en) 2001-02-16 2002-08-22 Ulrich Rudel Method for the preparation of optical (bio)chemical sensor devices
AU2005302484A1 (en) * 2004-10-28 2006-05-11 Microchips, Inc. Orthopedic and dental implant devices providing controlled drug delivery
EP2319558B1 (en) * 2006-03-14 2014-05-21 University Of Southern California Mems device for delivery of therapeutic agents
US20100318193A1 (en) 2007-03-08 2010-12-16 Desai Tejal A Topographically engineered structures and methods for using the same in regenerative medicine applications
EP2164425B1 (en) * 2007-03-16 2015-10-28 The Regents of The University of California Nanostructure surface coated medical implants and methods of using the same
US9023896B2 (en) 2009-05-04 2015-05-05 Psivida Us, Inc. Porous silicon drug-eluting particles

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5797898A (en) * 1996-07-02 1998-08-25 Massachusetts Institute Of Technology Microchip drug delivery devices
WO2000041740A2 (en) * 1999-01-11 2000-07-20 The Regents Of The University Of California Particles for oral delivery of peptides and proteins
US7622081B2 (en) * 2000-06-05 2009-11-24 California Institute Of Technology Integrated active flux microfluidic devices and methods
WO2004006840A2 (en) * 2002-07-12 2004-01-22 The Regents Of The University Of California Three dimensional cell patterned bioploymer scaffolds and method of making the same

Also Published As

Publication number Publication date
US20150119807A1 (en) 2015-04-30
CA2875146A1 (en) 2013-12-05
US9878137B2 (en) 2018-01-30
BR112014029760A2 (pt) 2017-06-27
IN2014DN10765A (https=) 2015-09-04
JP6336442B2 (ja) 2018-06-06
CA2875146C (en) 2022-03-22
EP2856259A4 (en) 2015-12-30
EP2856259A1 (en) 2015-04-08
WO2013181107A1 (en) 2013-12-05
EP2856259B1 (en) 2018-12-26
CN104412160A (zh) 2015-03-11
JP2015519366A (ja) 2015-07-09

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Granted publication date: 20190920