CN104398968A - Chinese medicinal preparation for treating hypnosia due to heavy dampness - Google Patents

Chinese medicinal preparation for treating hypnosia due to heavy dampness Download PDF

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CN104398968A
CN104398968A CN201410812422.9A CN201410812422A CN104398968A CN 104398968 A CN104398968 A CN 104398968A CN 201410812422 A CN201410812422 A CN 201410812422A CN 104398968 A CN104398968 A CN 104398968A
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hypnosia
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张国强
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/57Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/074Ganoderma
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/22Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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    • A61K36/60Moraceae (Mulberry family), e.g. breadfruit or fig
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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    • A61K36/88Liliopsida (monocotyledons)
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    • A61K9/48Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release

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Abstract

The invention discloses a Chinese medicinal preparation for treating hypnosia due to heavy dampness. The Chinese medicinal preparation is characterized by being prepared from the following raw materials in parts by weight: 15 parts of inner shell membranes of fowl's eggs, 20 parts of roots of climbing fig, 15 parts of herb of wilson passionflower, 15 parts of roots of petalformed meadowrue, 25 parts of tsaoko amomum fruit, 30 parts of all-grass of clustered knotweed, 12 parts of lucid ganoderma, 15 parts of Indian buead, 15 parts of roots of boxleaf syzygium, 15 parts of fructus alpiniae oxyphyllae, 10 parts of fruit of Indochina gragonplum, 18 parts of sweet Basil herb, 20 parts of stems and leaves of beechey fig and 5 parts of liquorice roots. The Chinese medicinal herbs for preparing the Chinese medicinal preparation interact mutually and take effect jointly, and the prepared Chinese medicinal preparation has the efficacies of eliminating dampness, strengthening the spleen and effectively treating hypnosia due to heavy dampness. The application of the Chinese medicinal preparation to 40 patients for years shows that the Chinese medicinal preparation can achieve an effective rate of 97.5%, has a good treatment effect and can ensure that the cured patient can not relapse into hypnosia.

Description

A kind of Chinese medicine preparation for the treatment of type of intense damp disorders of excessive sleepiness
Technical field
The present invention relates to a kind of Chinese medicine, particularly a kind of Chinese medicine preparation being used for the treatment of type of intense damp disorders of excessive sleepiness.
Background technology
Drowsinessly refer to day and night, sleepy constantly, that exhales can wake up, the disease of sleeping again after waking up.It is a kind of nervous system disease, it can cause can not inhibition sleep generation.These Sleep stages can often occur, and incident time contretemps, such as, when speaking, having a meal or drive.The traditional Chinese medical science is according to causing the reason of this disease the dialectical treatment of this disease to be divided into type of intense damp, spleen-deficient, blood stasis blocking type, deficiency of yang type four kinds of pattern of syndrome.The Therapeutic Method of disorders of excessive sleepiness has tcm therapy and western medicine therapy, acupuncture and moxibustion therapy etc., western medicine therapy mainly adopts to take stimulants and resembles modafinil(Provigil daytime), the medicines such as toluene salt (Ritalin and other brand names) or dextroamphetamine (Dexedrine), just respite sleepiness, after drug action subsides, enter Somnolence again at once, acupuncture and moxibustion therapy also can play certain effect, but onset is slower, cure rate is lower, tcm therapy is effective Therapeutic Method, because it can be treated from causing the basic reason of disorders of excessive sleepiness to start with, there is the effect reaching treating both the principal and secondary aspects of a disease.The Chinese medicine for the treatment of disorders of excessive sleepiness disclosed at present also exists the defects such as cure rate is lower.
Summary of the invention
The object of this invention is to provide a kind of Chinese medicine preparation for the treatment of type of intense damp disorders of excessive sleepiness, adopt Chinese medicine of the present invention, can effectively cure type of intense damp disorders of excessive sleepiness, therapeutic effect is good.
The technical scheme adopted for realizing above-mentioned purpose of the present invention is: a kind of Chinese medicine preparation for the treatment of type of intense damp disorders of excessive sleepiness, it is characterized in that being made up of the raw material of following weight proportion:
Membrana Follicularis ovi 15 parts, Radix Fici pumilae 20 parts, Herba Passiflorae Wilsonii 15 parts, Radix thalictri petaloidei 15 parts, Fructus Tsaoko 25 parts, Herba Polygoni caespitosi 30 parts, 15 parts, Poria, Radix Syzygii Buxifolii 15 parts, Fructus Alpiniae Oxyphyllae 15 parts, Fructus Dracontomeli Duperreani 10 parts, Herba Ocimi (Herba Ocimi Pilosi) 18 parts, Caulis et Folium Fici beecheyanae 20 parts, 5 parts, Radix Glycyrrhizae.
Source and the function of various medical materials involved in formula cure mainly as follows:
Membrana Follicularis ovi [source] medical material Ji Yuan: for Phasianidae animal man ovum gallinaceum incubates the egg membrane after chicken in eggshell.[nature and flavor] sweet in the mouth; Light; Property is put down.[return through] spleen; Stomach; Lung meridian.[function cures mainly] nourishing YIN and clearing away lung-heat; Sore; Removing nebula; Synthetism.Asthma is coughed outside main; Pharyngalgia aphonia; Lymphoid tuberculosis; Ulcer being unable to heal; The raw cataracta of order; The vertigo; Trauma fracture.
The root that Radix Fici pumilae [source] is moraceae plants Caulis fici pumilae (Fructus Fici Pumilae).[nature and flavor] are bitter, flat.[function cures mainly] expelling wind and removing dampness, channels sootheing and network vessel quickening.Control headache dizzy, articular rheumatic pain, puerperal exposure to wind.
The herb that Herba Passiflorae Wilsonii [source] is Passifloraceae plant Passiflora wilsonii.[nature and flavor] micro-hardship, temperature.[function cures mainly] relaxing muscles and tendons to promote blood circulation, removing dampness and killing parasites.Treating rheumatic arthritis, injury and bone fracture, hepatitis.Malaria, ascariasis.
Radix thalictri petaloidei [source] medical material Ji Yuan: be the root and rhizome of ranunculaceae plant Radix thalictri petaloidei.[nature and flavor] bitter in the mouth; Cold in nature.[return through] returns liver; Stomach; Large intestine channel.[function cures mainly] heat clearing away; Dampness; Removing toxic substances.Cure mainly damp-heat dysentery; Jaundice; Cough due to lung-heat; Conjunctival congestion and swelling pain; Carbuncle furuncle; Exudative dermatitis.
Fructus Tsaoko [source] medical material Ji Yuan: be the fruit of zingiberaceous plant Fructus Tsaoko.[nature and flavor] acrid in the mouth; Warm in nature.[return through] spleen; Stomach warp.[function cures mainly] dampness, warming middle-JIAO, eliminates the phlegm, preventing the attack (or recurrence) of malaria.Main coldness and pain in the epigastrium; Nausea and vomiting; Born of the same parents' diaphragm feeling of fullness; Have loose bowels and rush down; Dysentery; Malaria.
Herba Polygoni caespitosi [source] medical material Ji Yuan: be the herb of polygonaceae plant Herba Polygoni caespitosi.[nature and flavor] are pungent; Property is put down.[function cures mainly] heat clearing and damp drying; Spleen invigorating disappears infantile malnutrition; Promoting blood flow to regulate menstruation; Removing toxic substances and promoting subsidence of swelling.Master has loose bowels; Dysentery; Infantile malnutrition; Menoxenia; Eczema; Tinea pedis; Venom.
Poria [source] this product is the dry sclerotia of On Polyporaceae Poria Poria cocos (Schw.) Wolf.[nature and flavor] are sweet, light, flat.[return through] GUIXIN, lung, spleen, kidney channel.[function cures mainly] promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming.For edema oliguria, phlegm retention vertigo and palpitation, insufficiency of the spleen lack of appetite, have loose bowels in loose stool, irritability, palpitation with fear insomnia.
Radix Syzygii Buxifolii [source] medical material Ji Yuan: be root or the root bark of myrtle Radix Syzygii Buxifolii.[nature and flavor] sweet in the mouth; Micro-hardship; Pungent; Property is put down.[return through] returns kidney; Spleen; Liver Channel.[function cures mainly] invigorating spleen to remove dampness; Relieving asthma; Dissipating blood stasis for subsidence of swelling.Master breathes with cough; Edema; Stranguria with turbid discharge; Lithangiuria; Dysentery; Hepatitis; Uterine prolapse; Rheumatalgia; Hernia; Orchitis; Hemorrhoid; Carbuncle; Burn due to hot liquid or fire; Treating swelling and pain by traumatic injury
The fruit that Fructus Alpiniae Oxyphyllae [source] is zingiberaceous plant Fructus Alpiniae Oxyphyllae.[nature and flavor] are pungent, temperature.[return through] enters spleen, kidney channel.[function cures mainly] warming the spleen, warming the kidney, solid and gas, arresting seminal emission.Control cold air stomachache, invasion by pathogenic cold vomit and diarrhoea, many salivas, seminal emission, dribbling urination, night many urine.
Fructus Dracontomeli Duperreani [source] medical material Ji Yuan: be the fruit of Anacardiaceae plant man face.[nature and flavor] are sweet; Acid; Cool in nature.[return through] spleen; Stomach; Liver Channel.[function cures mainly] stomach invigorating; Promote the production of body fluid; Relieving alcoholic intoxication; Removing toxic substances.Main inappetence; Calentura is thirsty; Drunk; Laryngopharynx swelling and pain; Pathogenic wind-toxic sore is itched.
Herba Ocimi (Herba Ocimi Pilosi) [source] medical material Ji Yuan: be the herb of labiate Herba Ocimi (Herba Ocimi Pilosi).[nature and flavor] acrid in the mouth; Warm in nature.[function cures mainly] invigorating the spleen for eliminating dampness; Expelling wind and activating blood circulation.Main wet cloudy taste; Indigestion and loss of appetite stomachache; Vomiting and diarrhoea; Fever caused by exogenous pathogens; Menoxenia; Traumatic injury; Skin eczema.
Caulis et Folium Fici beecheyanae [source] medical material Ji Yuan: be stem, the leaf of moraceae plants Fructus Fici Beecheyanae.[nature and flavor] are sweet light, temperature, nontoxic.[return through] enters lung, spleen, kidney three warp.[function cures mainly] invigorating the spleen and replenishing QI, invigorating the spleen for eliminating dampness, bone and muscle strengthening, detumescence, promoting blood circulation and detoxication.Dispelling the wind and dampness pathogens arthralgia, the middle deficiency of vital energy is weak, and QI and blood is on the decline, and extremity are aching and limp, stiffness of the muscle and joint, traumatic injury, amenorrhea, galactostasis.
Radix Glycyrrhizae [source] this product is the dry root of glycyrrhizic legume Glycyrrhiza uralensis Fisch., Glycyrrhiza inflata Bat. Glycyrrhiza inflata Bat. or Glycyrrhiza glabra L. Glycyrrhiza glabra L..[nature and flavor] are sweet, flat.[return through] GUIXIN, lung, spleen, stomach warp.[function cures mainly] invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.For weakness of the spleen and stomach, fatigue and weakness, shortness of breath and palpitation, cough with copious phlegm, the anxious pain of gastral cavity abdomen, extremity contraction, carbuncle sore tumefacting virus, cushion toxicity, strong.
Type of intense damp disorders of excessive sleepiness is mainly in rain wet season, or plump people.Its clinical symptoms shows as: anorexia uncomfortable in chest, and heavy sensation of the body is drowsiness, and tongue is greasy in vain, relaxed and soft pulse.[method for the treatment of] is drying damp and strengthening spleen.The present invention adopts the formula of science, the Membrana Follicularis ovi energy nourishing YIN and clearing away lung-heat adopted in formula, sore, removing nebula; Radix Fici pumilae energy expelling wind and removing dampness, channels sootheing and network vessel quickening; Herba Passiflorae Wilsonii energy relaxing muscles and tendons to promote blood circulation, removing dampness and killing parasites; Radix thalictri petaloidei energy dampness, removing toxic substances; Fructus Tsaoko energy dampness, warming middle-JIAO, eliminates the phlegm, preventing the attack (or recurrence) of malaria; Herba Polygoni caespitosi energy heat clearing and damp drying, spleen invigorating disappears infantile malnutrition, promoting blood flow to regulate menstruation; Poria energy promoting diuresis to eliminate damp pathogen, spleen invigorating mind calming; Radix Syzygii Buxifolii energy invigorating spleen to remove dampness, relievings asthma, dissipating blood stasis for subsidence of swelling; Fructus Alpiniae Oxyphyllae energy warming the spleen, warming the kidney, solid and gas, arresting seminal emission; The stomach invigorating of Fructus Dracontomeli Duperreani energy; The invigorating the spleen for eliminating dampness of Herba Ocimi (Herba Ocimi Pilosi) energy, expelling wind and activating blood circulation; The invigorating the spleen and replenishing QI of Caulis et Folium Fici beecheyanae energy, invigorating the spleen for eliminating dampness, bone and muscle strengthening; Radix Glycyrrhizae energy invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, relieving spasm to stop pain, coordinating the actions of various ingredients in a prescription.Cooperatively interact between each medicine in formula, synergism, made Chinese medicine has drying damp and strengthening spleen effect, can effectively treat type of intense damp disorders of excessive sleepiness, for many years by showing the use of 40 patients, effective percentage reaches 97.5%, therapeutic effect is good, no longer recurs more.
Below in conjunction with clinical laboratory data, beneficial effect of the present invention is described:
1, sampling approach
Be diagnosed as the patient of type of intense damp disorders of excessive sleepiness from my unit over nearly 8 years, the routine patient of random selecting 80, wherein, man 38 example, female 42 example, age 17-36 year, the season patient that multiple rain is wet is relatively many, and obese patient is more, and clinical symptoms shows as: head covers as wrapped up in, anorexia uncomfortable in chest, heavy sensation of the body is drowsiness, and limbs are heavy, occasionally accompany edema, feeling of oppression and fullness in the chest and epigastrium, anorexia, nausea, greasy fur on tongue, relaxed and soft pulse.Be divided into matched group and treatment group at random, often organize each 40 people.The data there was no significant differences such as two groups of ages, have comparability.
2, test method
2.1 matched group patients take Pingwei San (Chen Shiwen etc. " formulary of peaceful benevolent dispensary ") and add taste.Prescription: Rhizoma Atractylodis 15 grams, Cortex Magnoliae Officinalis 12 grams, Pericarpium Citri Reticulatae 6 grams, Herba Pogostemonis 12 grams, Semen Coicis 18 grams, Rhizoma Pinelliae Preparatum 12 grams, Folium Microcoris paniculatae 12 grams, 6 grams, Radix Glycyrrhizae.Be decocted in water for oral dose.By specification is taken, 1 month course for the treatment of.
The oral the present invention of 2.2 treatment group according to the obtained capsule of specific embodiment 1, early, middle and late each once.1 month course for the treatment of.
3, criterion of therapeutical effect and therapeutic outcome
3.1 criterions of therapeutical effect:
Clinical recovery: clinical symptoms, the sign of type of intense damp disorders of excessive sleepiness disappear or substantially disappear; Effective: clinical symptoms, the sign of type of intense damp disorders of excessive sleepiness are obviously improved; Effective: clinical symptoms, the sign of type of intense damp disorders of excessive sleepiness all take a favorable turn; Invalid: clinical symptoms, the sign of type of intense damp disorders of excessive sleepiness are all not improved or increase the weight of.
3.2 treatment statistical results are in table 1.
Table 1 liang group comparitive study
As can be seen here, the medicine adopting prescription of the present invention obtained can safe and effective treatment type of intense damp disorders of excessive sleepiness.
Detailed description of the invention
Below in conjunction with the concrete example implemented, further detailed description is done to the present invention.
Embodiment 1
Take Membrana Follicularis ovi 15 grams, Radix Fici pumilae 20 grams, Herba Passiflorae Wilsonii 15 grams, Radix thalictri petaloidei 15 grams, Fructus Tsaoko 25 grams, Herba Polygoni caespitosi 30 grams, 15 grams, Poria, Radix Syzygii Buxifolii 15 grams, Fructus Alpiniae Oxyphyllae 15 grams, Fructus Dracontomeli Duperreani 10 grams, Herba Ocimi (Herba Ocimi Pilosi) 18 grams, Caulis et Folium Fici beecheyanae 20 grams, 5 grams, Radix Glycyrrhizae, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then after mixing homogeneously with 3 grams of Radix Phytolaccae pollen, incapsulate shell, the capsule of adult normal's 1 day consumption must be met.
Be used for the treatment of type of intense damp disorders of excessive sleepiness.Oral, every bu is taken for early, middle and late three times.
Specific embodiment 2
Take Membrana Follicularis ovi 15 grams, Radix Fici pumilae 20 grams, Herba Passiflorae Wilsonii 15 grams, Radix thalictri petaloidei 15 grams, Fructus Tsaoko 25 grams, Herba Polygoni caespitosi 30 grams, 15 grams, Poria, Radix Syzygii Buxifolii 15 grams, Fructus Alpiniae Oxyphyllae 15 grams, Fructus Dracontomeli Duperreani 10 grams, Herba Ocimi (Herba Ocimi Pilosi) 18 grams, Caulis et Folium Fici beecheyanae 20 grams, 5 grams, Radix Glycyrrhizae, add 10 times of water gagings, decoct 2 hours, filter; Filtering residue adds 8 times of water gagings, decocts 1.5 hours, filters; Merging filtrate, concentrated, dry, then after mixing homogeneously with 3 grams of Radix Phytolaccae pollen, packaging, must meet the powder of adult normal's 1 day consumption.
Be used for the treatment of type of intense damp disorders of excessive sleepiness.Oral, every bu is taken for early, middle and late three times.
Specific embodiment 3
Take Membrana Follicularis ovi 15 grams, Radix Fici pumilae 20 grams, Herba Passiflorae Wilsonii 15 grams, Radix thalictri petaloidei 15 grams, Fructus Tsaoko 25 grams, Herba Polygoni caespitosi 30 grams, 15 grams, Poria, Radix Syzygii Buxifolii 15 grams, Fructus Alpiniae Oxyphyllae 15 grams, Fructus Dracontomeli Duperreani 10 grams, Herba Ocimi (Herba Ocimi Pilosi) 18 grams, Caulis et Folium Fici beecheyanae 20 grams, 5 grams, Radix Glycyrrhizae, add 8 times of water gagings, decoct 1.5 hours, filter; Filtering residue adds 6 times of water gagings, decocts 1 hour, filters; Merging filtrate, concentrated, dry, then after mixing homogeneously with 3 grams of Radix Phytolaccae pollen, granulate according to this area common process, packaging, must meet the granule of adult normal's 1 day consumption.
Be used for the treatment of type of intense damp disorders of excessive sleepiness.Oral, every bu is taken for early, middle and late three times.

Claims (1)

1. treat a type of intense damp disorders of excessive sleepiness's Chinese medicine preparation, it is characterized in that being made up of the raw material of following weight proportion:
Membrana Follicularis ovi 15 parts, Radix Fici pumilae 20 parts, Herba Passiflorae Wilsonii 15 parts, Radix thalictri petaloidei 15 parts, Fructus Tsaoko 25 parts, Herba Polygoni caespitosi 30 parts, Ganoderma 12 parts, 15 parts, Poria, Radix Syzygii Buxifolii 15 parts, Fructus Alpiniae Oxyphyllae 15 parts, Fructus Dracontomeli Duperreani 10 parts, Herba Ocimi (Herba Ocimi Pilosi) 18 parts, Caulis et Folium Fici beecheyanae 20 parts, 5 parts, Radix Glycyrrhizae.
CN201410812422.9A 2014-12-24 2014-12-24 Chinese medicinal preparation for treating hypnosia due to heavy dampness Withdrawn CN104398968A (en)

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Application publication date: 20150311