CN104398967A - 一种治疗脾气虚弱证型嗜睡病的中药制剂 - Google Patents

一种治疗脾气虚弱证型嗜睡病的中药制剂 Download PDF

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CN104398967A
CN104398967A CN201410811403.4A CN201410811403A CN104398967A CN 104398967 A CN104398967 A CN 104398967A CN 201410811403 A CN201410811403 A CN 201410811403A CN 104398967 A CN104398967 A CN 104398967A
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张国强
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Abstract

本发明公开了一种治疗脾气虚弱证型嗜睡病的中药制剂，其特征是由下列重量配比的原料制成的：橹罟子15份、番荔枝12份、黄精15份、太子参12份、墨旱莲20份、女贞子20份、黄蜀葵子8份、九翅豆蔻12份、黄花蒿子10份、冬葵根12份、紫河车3份、冬虫夏草3份、旋花根10份、头发七12份、甘草5份。本发明配方合理，疗效可靠，是治疗脾气虚弱证型嗜睡病的理想药物。

Description

一种治疗脾气虚弱证型嗜睡病的中药制剂
技术领域
本发明涉及一种中药，特别是一种用于治疗脾气虚弱证型嗜睡病的中药制剂。 
背景技术
嗜睡是指不分昼夜，时时欲睡，呼之能醒，醒后复睡的病证。它是一种神经性疾病，它能引起不可抑制性睡眠的发生。这些睡眠阶段会经常发生，且易发生的时间不合适宜，例如当说话、吃饭或驾车时。中医依据引起该病的原因将该病的辩证治疗分为湿胜型、脾虚型、瘀阻型、阳虚型四种证型。嗜睡病的治疗方法有中医疗法及西医疗法、针灸治疗等，西医疗法主要采用白天服用兴奋剂象modafinil（Provigil）、甲苯盐（Ritalin和其他品牌名）或右旋安非他命（Dexedrine）等药物，只是暂时缓解睡意，药效消失后，马上又进入嗜睡状态，针灸治疗也可以起到一定的效果，但起效较慢，治愈率较低，中医疗法是行之有效的治疗方法，因为它可以从引起嗜睡病的根本原因入手进行治疗，具有达到标本兼治的效果。目前所公开的治疗嗜睡病的中药存在着治愈率较低等缺陷。 
发明内容
本发明的目的是提供一种治疗脾气虚弱证型嗜睡病的中药制剂，采用本发明的中药，能有效的治愈脾气虚弱证型嗜睡病，治疗效果好。 
为实现本发明的上述目的所采用的技术方案是：一种治疗脾气虚弱证型嗜睡病的中药制剂，其特征是由下列重量配比的原料制成的： 
橹罟子15份、番荔枝12份、黄精15份、太子参12份、墨旱莲20份、女贞子20份、黄蜀葵子8份、九翅豆蔻12份、黄花蒿子10份、冬葵根12份、紫河车3份、冬虫夏草3份、旋花根10份、头发七12份、甘草5份。
配方中所涉及到的各种药材的来源及功能主治如下: 
橹罟子【来源】药材基源：为露兜树科植物露兜树的核果。【性味】味辛；淡；性凉。【归经】肾；脾；肝；胃经。【功能主治】补脾益血；行气止痛；化痰利湿；明目。主痢疾；胃痛；咳嗽；疝气；睾丸炎；痔疮小便不利；目生翳障。
番荔枝【来源】药材基源：为番荔枝科植物番荔枝的果实。【性味】味甘；性寒。【功能主治】补脾胃；清热解毒；杀虫。主恶疮肿痛；肠寄生虫病。 
黄精【来源】本品为百合科植物滇黄精Polygonatum kingianum Coll.et Hemsl.、黄精Polygonatum sibiricum Red.或多花黄精Polygonatum cyrtonema Hua 的干燥根茎。【性味】甘，平。【归经】归脾、肺、肾经。【功能主治】补气养阴，健脾，润肺，益肾。用于脾胃虚弱，体倦乏力，口干食少，肺虚燥咳，精血不足，内热消渴。 
太子参【来源】本品为石竹科植物孩儿参Pseudostellaria heterophylla （Miq.）Pax ex Pax et Hoffm.的干燥块根。【性味】甘、微苦，平。【归经】归脾、肺经。【功能主治】益气健脾，生津润肺。用于脾虚体倦，食欲不振，病后虚弱，气阴不足，自汗口渴，肺燥干咳。 
墨旱莲【来源】本品为菊科植物鳢肠Eclipta prostrata L.的干燥地上部分。【性味】甘、酸，寒。【归经】归肾、肝经。【功能主治】滋补肝肾，凉血止血。用于牙齿松动，须发早白，眩晕耳鸣，腰膝酸软，阴虚血热、吐血、衄血、尿血，血痢，崩漏下血，外伤出血。 
女贞子【来源】本品为木犀科植物女贞Ligustrum lucidum Ait. 的干燥成熟果实。【性味】甘、苦，凉。【归经】归肝、肾经。【功能主治】滋补肝肾，明目乌发。用于眩晕耳鸣，腰膝酸软，须发早白，目暗不明。 
黄蜀葵子【来源】为锦葵科植物黄蜀葵的种子。【性味】甘，寒，滑。【功能主治】利水，消肿，通乳。治淋病，水肿，乳汁不通，痈肿，跌扑损伤，骨折。 
九翅豆蔻【来源】药材基源：为姜科植物九翅豆蔻的果实或根。【性味】味辛；性温。【归经】脾；胃经。【功能主治】温中止痛；开胃消食。主脘腹冷痛；腹胀；不思饮食；嗳腐吞酸。 
黄花蒿子【来源】为菊科植物黄花蒿的果实。【性味】凉，无毒。【功能主治】治劳，下气，开胃，止盗汗。 
冬葵根【来源】为锦葵科植物冬葵的根。【性味】甘辛，寒。【功能主治】清热，解毒，利窍，通淋。治消渴，淋病，二便不利，乳汁少，白带，虫螫伤。 
紫河车【来源】本品为健康人的干燥胎盘。【性味】甘、咸，温。【归经】归心、肺、肾经。【功能主治】温肾补精，益气养血。用于虚劳羸瘦，骨蒸盗汗，咳嗽气喘，食少气短，阳痿遗精，不孕少乳。 
冬虫夏草【来源】本品为麦角菌科真菌冬虫夏草菌Cordyceps sinensis （Berk.）Sacc. 寄生在蝙蝠蛾科昆虫幼虫上的子座及幼虫尸体的复合体。【性味】甘，平。【归经】归肺、肾经。【功能主治】补肺益肾，止血化痰。用于久咳虚喘，劳嗽咯血，阳痿遗精，腰膝酸痛。 
旋花根【来源】药材基源：为双子叶植物药旋花科植物篱天剑的根。【性味】甘；微苦；温。【归经】肺；肝；肾经。【功能主治】益气补虚；续筋接骨；解毒；杀虫。主丹毒；劳损；金疮；蛔虫病。 
头发七【来源】药材基源：为松萝科植物亚洲树发、双色树发、树发、沟树发的地衣体。【性味】淡；性平。【归经】肝；肾；膀胱经。【功能主治】滋肾养肝；涩精止汗；利水消肿；收湿敛疮。。主肾虚体弱；头目眩晕；心悸；遗精；盗汗；淋症；水肿；黄水疮。 
甘草【来源】 本品为豆科植物甘草 Glycyrrhiza uralensis Fisch.、胀果甘草 Glycyrrhiza inflata Bat. 或光果甘草 Glycyrrhiza glabra L. 的干燥根。【性味】 甘，平。【归经】 归心、肺、脾、胃经 。【功能主治】 补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药。用于脾胃虚弱，倦怠乏力，心悸气短，咳嗽痰多，脘腹、四肢挛急疼痛，痈肿疮毒，缓解药物毒性、烈性。 
脾气虚弱证型嗜睡病的临床症状表现为：嗜睡多卧,倦怠乏力,饭后尤甚,伴纳少便溏,面色萎黄,苔薄白,脉虚弱。治法:健脾益气。 
本发明采用科学的配方，配方中所采用的橹罟子具有补脾益血，行气止痛的功效；番荔枝具有补脾胃的功效；黄精具有补气养阴，健脾，润肺，益肾的功效；太子参具有益气健脾，生津润肺的功效；墨旱莲具有滋补肝肾，凉血止血的功效；女贞子具有滋补肝肾的功效；黄蜀葵子具有利水，消肿的功效；九翅豆蔻具有温中止痛，开胃消食的功效；黄花蒿子具有治劳，下气，开胃，止盗汗的功效；冬葵根具有利窍，通淋的功效；紫河车具有温肾补精，益气养血的功效；冬虫夏草具有补肺益肾的功效；旋花根具有益气补虚；续筋接骨的功效；头发七具有滋肾养肝，涩精止汗的功效；甘草具有补脾益气，清热解毒，祛痰止咳，缓急止痛，调和诸药的功效。配方中的各药物，相互配合，协同作用，共凑健脾益气的功效，能有效治疗脾气虚弱证型嗜睡病，多年来，通过对多名患者的使用表明，有效率达100%，治疗效果好，愈后不再复发。 
下面结合临床实验数据来说明本发明的有益效果： 
1、抽样方法
从我单位近8年来确诊为脾气虚弱证型嗜睡病的患者中，随机选取100例病人，其中，男50例，女50例，年龄22-50岁，临床症状表现为: 嗜睡多卧,倦怠乏力,饭后尤甚,伴纳少便溏,面色萎黄,苔薄白,脉虚弱。随机分为对照组和治疗组，每组各50人。两组年龄等资料无显著性差异，具有可比性。
2、试验方法 
2．1对照组患者服用六君子汤(虞抟《医学正传》)加减。处方：党参15克，白术12克，茯苓12克，法半夏12克，陈皮6克，黄芪15克，神曲10克，麦芽20克，甘草6克。水煎服。。水煎服。按说明书服用，疗程1个月。
2．2治疗组口服本发明按照具体实施例1制得的胶囊，早、中、晚各一次。疗程1个月。 
3、疗效标准及治疗结果 
3.1疗效标准：
临床痊愈：脾气虚弱证型嗜睡病的临床症状、体征消失或基本消失；显效：脾气虚弱证型嗜睡病的临床症状、体征明显改善；有效：脾气虚弱证型嗜睡病的临床症状、体征均有好转；无效：脾气虚弱证型嗜睡病的临床症状、体征均无明显改善或加重。
3.2治疗统计结果见表1。 
表1两组疗效比较 
由此可见，采用本发明的组方制得的药物能够安全有效治疗脾气虚弱证型嗜睡病。
具体实施方式
下面结合具体实施的例子对本发明做进一步详细的描述。 
实施例1 
称取橹罟子15克、番荔枝12克、黄精15克、太子参12克、墨旱莲20克、女贞子20克、黄蜀葵子8克、九翅豆蔻12克、黄花蒿子10克、冬葵根12克、旋花根10克、头发七12克、甘草5克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再与紫河车粉3克、冬虫夏草粉3克混合均匀后，装入胶囊壳，即得符合正常成人1天用量的胶囊剂。
用于治疗脾气虚弱证型嗜睡病。口服，每日分早、中、晚三次服用。 
具体实施例2 
称取橹罟子15克、番荔枝12克、黄精15克、太子参12克、墨旱莲20克、女贞子20克、黄蜀葵子8克、九翅豆蔻12克、黄花蒿子10克、冬葵根12克、旋花根10克、头发七12克、甘草5克，加10倍量水，煎煮2小时，过滤；滤渣加8倍量水，煎煮1.5小时，过滤；合并滤液，浓缩，干燥，再与紫河车粉3克、冬虫夏草粉3克混合均匀后，包装，即得符合正常成人1天用量的散剂。
用于治疗脾气虚弱证型嗜睡病。口服，每日分早、中、晚三次服用。 
具体实施例3 
称取橹罟子15克、番荔枝12克、黄精15克、太子参12克、墨旱莲20克、女贞子20克、黄蜀葵子8克、九翅豆蔻12克、黄花蒿子10克、冬葵根12克、旋花根10克、头发七12克、甘草5克，加8倍量水，煎煮1.5小时，过滤；滤渣加6倍量水，煎煮1小时，过滤；合并滤液，浓缩，干燥，再与紫河车粉3克、冬虫夏草粉3克混合均匀后，按照本领域常规工艺制粒，包装，即得符合正常成人1天用量的颗粒剂。
用于治疗脾气虚弱证型嗜睡病。口服，每日分早、中、晚三次服用。 

Claims (1)

1. 一种治疗脾气虚弱证型嗜睡病的中药制剂，其特征是由下列重量配比的原料制成的：
橹罟子15份、番荔枝12份、黄精15份、太子参12份、墨旱莲20份、女贞子20份、黄蜀葵子8份、九翅豆蔻12份、黄花蒿子10份、冬葵根12份、紫河车3份、冬虫夏草3份、旋花根10份、头发七12份、甘草5份。
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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105362814A (zh) * 2015-12-04 2016-03-02 孙世林 一种治疗肝肾两虚证型多寐病的中药
CN105816726A (zh) * 2016-05-24 2016-08-03 孙萌 一种治疗气虚的中药组合物

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105362814A (zh) * 2015-12-04 2016-03-02 孙世林 一种治疗肝肾两虚证型多寐病的中药
CN105816726A (zh) * 2016-05-24 2016-08-03 孙萌 一种治疗气虚的中药组合物

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