CN104398961A - Traditional Chinese medicine preparation for treating viral hepatitis - Google Patents
Traditional Chinese medicine preparation for treating viral hepatitis Download PDFInfo
- Publication number
- CN104398961A CN104398961A CN201410691400.1A CN201410691400A CN104398961A CN 104398961 A CN104398961 A CN 104398961A CN 201410691400 A CN201410691400 A CN 201410691400A CN 104398961 A CN104398961 A CN 104398961A
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Abstract
The invention discloses a traditional Chinese medicine preparation for treating viral hepatitis. The traditional Chinese medicine preparation is prepared from the following raw materials as effective components: ammonia ester, cornus capitata, radix bupleuri, oriental wormwood, isatis roots, angelica sinensis, astragalus membranaceus, schisandra chinensis, burdock, rabdosia rubescens, rhizoma anemarrhenae, cardamom and irisquinone capsules. As the raw materials are compatible with one another, the traditional Chinese medicine preparation disclosed by the invention can meet the traditional Chinese medicine and modern medical research theories, has the effecacies of removing heat from the liver and removing toxicity, smoothing the liver and removing depression, promoting blood circulation to remove blood stasis, removing summer-heat and removing evil as well as tonifying spleen and kidney, has the function of effectively improving the body immunity and reducing the complication, is safe and free of toxic or side effect, realizes the purpose of treating both symptoms and root causes, and is worthy of clinical popularization and application,.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation for the treatment of viral hepatitis.
Background technology
Viral hepatitis is the infectious disease caused by multiple hepatitis virus, there is infectiousness strong, popular wide general, propagate by way of complexity, sickness rate is high comparatively, main manifestations is weak, poor appetite, Nausea and vomiting, hepatomegaly and liver function injury clinically, and some patients can have jaundice and heating, and inapparent infection is more common.Viral hepatitis divides A type, B-mode, the third type and penta type etc., acute hepatitis, and mostly recovered in 6 months, B-mode, hepatitis C, mutability is chronic, and minority can develop into liver cirrhosis.Viral hepatitis is universal infectious disease, and the annual patient by hepatitis torment is hundreds of millions of, and wherein more than 200 ten thousand Crinis Carbonisatus life and death are died.
The various neuropathic condition that treatment viral hepatitis and viral hepatitis cause, generally comprise Western medicine Drug therapy and topical therapeutic, although this type of therapy prognosis bona, but because medicine is mostly Western medicine, Western medicine side effect is large, many patients have untoward reaction to Western medicine, and the therapeutic effect for viral hepatitis is not remarkable.
Summary of the invention
The invention provides a kind of Chinese medicine preparation for the treatment of viral hepatitis, it selects medical material compatibility suitable, meet Chinese medicine and modern medicine study theory, there is removing liver heat and toxic substances, soothing liver-QI reach strongly fragrant, blood circulation promoting and blood stasis dispelling, removing summer-heat is eliminating evil, effect of training spleen reinforcing kidney, and effectively can improve body's immunity, minimizing complication, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for viral hepatitis, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are: Fructus Cudraniae Cochinchinensis 5 ~ 9 parts, Radix Bupleuri 9 ~ 13 parts, Herba Artemisiae Scopariae 20 ~ 24 parts, Radix Isatidis 15 ~ 19 parts, Radix Angelicae Sinensis 9 ~ 13 parts, the Radix Astragali 10 ~ 14 parts, Fructus Schisandrae Chinensis 15 ~ 19 parts, Fructus Arctii 6 ~ 10 parts, Rabdosia rubescens 4 ~ 8 parts, Radix seu Herba Gymnopteris vestitae 6 ~ 10 parts, Elettaria cardamomum (L.) Maton 5 ~ 9 parts, Semen Iridis 4 ~ 8 parts, ammoniac 3 ~ 7 parts.
As preferably, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are: Fructus Cudraniae Cochinchinensis 5 ~ 7 parts, Radix Bupleuri 9 ~ 11 parts, Herba Artemisiae Scopariae 20 ~ 22 parts, Radix Isatidis 15 ~ 17 parts, Radix Angelicae Sinensis 9 ~ 11 parts, the Radix Astragali 10 ~ 12 parts, Fructus Schisandrae Chinensis 15 ~ 17 parts, Fructus Arctii 6 ~ 8 parts, Rabdosia rubescens 4 ~ 6 parts, Radix seu Herba Gymnopteris vestitae 6 ~ 8 parts, Elettaria cardamomum (L.) Maton 5 ~ 7 parts, Semen Iridis 4 ~ 6 parts, ammoniac 3 ~ 5 parts.
As preferably, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are: Fructus Cudraniae Cochinchinensis 7 parts, Radix Bupleuri 11 parts, Herba Artemisiae Scopariae 22 parts, Radix Isatidis 17 parts, Radix Angelicae Sinensis 11 parts, the Radix Astragali 12 parts, Fructus Schisandrae Chinensis 17 parts, Fructus Arctii 8 parts, Rabdosia rubescens 6 parts, Radix seu Herba Gymnopteris vestitae 8 parts, Elettaria cardamomum (L.) Maton 7 parts, Semen Iridis 6 parts, ammoniac 5 parts.
As preferably, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are: Fructus Cudraniae Cochinchinensis 5 parts, Radix Bupleuri 9 parts, Herba Artemisiae Scopariae 20 parts, Radix Isatidis 15 parts, Radix Angelicae Sinensis 9 parts, the Radix Astragali 10 parts, Fructus Schisandrae Chinensis 15 parts, Fructus Arctii 6 parts, Rabdosia rubescens 4 parts, Radix seu Herba Gymnopteris vestitae 6 parts, Elettaria cardamomum (L.) Maton 5 parts, Semen Iridis 4 parts, ammoniac 3 parts.
A kind of preparation method for the treatment of the Chinese medicine preparation of viral hepatitis, comprise following processing step: Fructus Cudraniae Cochinchinensis, Radix Bupleuri, Herba Artemisiae Scopariae, Radix Isatidis, Radix Angelicae Sinensis, the Radix Astragali, Fructus Schisandrae Chinensis, Fructus Arctii, Rabdosia rubescens, Radix seu Herba Gymnopteris vestitae, Elettaria cardamomum (L.) Maton, Semen Iridis are cleaned by (1), put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) ammoniac is put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of viral hepatitis of the present invention.
The property of medicine of the present invention's Chinese medicine used is as follows:
The resin of ammoniac [source] samphire ammonia grindelia.[nature and flavor] bitter in the mouth and pungent.[function cures mainly] opens liver resistance, dissolves calculus, and warm brain is except insane, and strong muscle is good for flesh, strengthens consciousness etc.The dirty retardance for the treatment of the liver, kidney stone, serious sinusitis with purulent discharge is insane silly, paralysis, numb limbs and tense tendons etc.
Fructus Cudraniae Cochinchinensis [source] Cornaceae Macrocarpium plant head Dendronenthamia japonica var.chinensis, is used as medicine with leaf, fruit.Fruit picking in autumn, using fresh herb or dry; The leaf four seasons can adopt, and dry levigation.[function cures mainly] heat-clearing and toxic substances removing, the capable water of function of gallbladder promoting, eliminating stagnated food and killing intestinal worms.For food stagnation flatulence, infantile malnutrition, hepatitis, ascariasis.
The dry root of Radix Bupleuri [source] umbelliferae bupleurum or Radix Bupeuri Scorzonerfolii..[function cures mainly] reconciling superficies and interior, soothing the liver, yang invigorating.For cold, fever, alternate attack of chill and fever, distending pain in the chest and hypochondrium, menoxenia, sub-official's prolapsus, proctoptosis.
The dry aerial parts that Herba Artemisiae Scopariae [source] is feverfew Artemisia scoparia Waldst. et Kit..[nature and flavor] are bitter, pungent, are slightly cold.[return through] returns spleen, stomach, liver, gallbladder meridian.[function cures mainly] clearing away damp-heat, jaundice eliminating subcutaneous ulcer.For jaundice oliguria, eczema pruritus; Infectious jaundice type hepatitis.
The dry root of Radix Isatidis [source] cruciferae isatis.[nature and flavor] are bitter, cold.[return through] GUIXIN, stomach warp.[function cures mainly] heat-clearing and toxic substances removing, removing heat from blood sore-throat relieving.For maculae caused by violent heat pathogen, crimson tongue is purple dark, mumps, sore throat, scarlet fever, major part pestilence, erysipelas, carbuncle.
The dry root of Radix Angelicae Sinensis [source] umbelliferae angelica.[nature and flavor] sweet, acrid, warm.[return through] returns liver, the heart, spleen channel.[function cures mainly] is enriched blood and is invigorated blood circulation, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For blood deficiency and yellow complexion, dizzy cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, dryness of the intestine constipation, rheumatic arthralgia, injury from falling down, ulcer sores.Radix Angelicae Sinensis (processed with wine) promoting blood circulation to restore menstrual flow.For amenorrhea dysmenorrhea, rheumatic arthralgia, injury from falling down.
The dry root of the Radix Astragali [source] leguminous plant Radix Astagali.[nature and flavor] are sweet, temperature.[return through] returns lung, spleen channel.[function cures mainly] invigorating QI to consolidate the body surface resistance, diuresis poison holding, evacuation of pus, expelling pus and promoting granulation.
The dry mature fruit of Fructus Schisandrae Chinensis [source] magnoliaceae schisandra.[nature and flavor] are sour, sweet, temperature.[return through] returns lung, the heart, kidney channel.[function cures mainly] restrains astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia.
Fructus Arctii [source] this product is the dry mature fruit of feverfew Fructus Arctii.[nature and flavor] are pungent, bitter, cold.[return through] attaches to the lung and stomach meridians.[function cures mainly] dispelling wind and heat pathogens, lung qi dispersing rash, resolving toxin and disinhibiting the throat.
Rabdosia rubescens [source] Labiatae Rabdosia plant is cracked rice fork, is used as medicine with Herb.[function cures mainly] this product Herb crude preparation by using clinical observation on the therapeutic effect, to esophagocardial carcinoma, hepatocarcinoma, breast carcinoma, rectal cancer have certain mitigation.Radiocurable side reaction can be prevented and treated, acute, chronic pharyngitis, tonsillitis, parotitis, tracheitis, chronic persistent hepatitis etc.
Radix seu Herba Gymnopteris vestitae [source] is the rhizome of Ying Wei section plant Oriolus chinensis diffusus tail.[nature and flavor] bitter in the mouth, pungent, property is cold; Mild toxicity.[function cures mainly] removing food stagnancy, purges heat, sore-throat relieving, relieving constipation.Cure mainly food stagnation distension.Laryngopharynx swelling and pain, constipation, tooth swelling around the eyes pain, traumatic injury wound is swollen, furuncle toxic swelling, Serpentis lyssodexis.
The dry mature fruit of Elettaria cardamomum (L.) Maton [source] zingiberaceous plant Elettaria cardamomum (L.) Maton.[nature and flavor] taste micro-pungent, gas is fragrant.[function cures mainly] dampness heat-dissipating, the vigorous liquid matter of dysregulation, mend the fragrant mouth of stomach, help digestion loose gas, sending down the abnormal ascending QI pain relieving, the calm refreshing heart.Cure mainly raw property or eat liquid matter disease, as insufficiency of stomach halitosis, dyspepsia abdominal distention, dyspepsia, nausea and vomiting, stomachache poor appetite, cold cardiopalmus etc." note doctor allusion quotation ": " cold relieving tonifying liver, warming middle-JIAO helps digestion, sending down the abnormal ascending QI emesis etc.; Control cold deficiency of the liver, cold syndrome of the stomach food stagnation, nausea and vomiting etc.”
The seed that Semen Iridis [source] is Ying Wei section plant Chinese small iris.[nature and flavor] sweet in the mouth.[function cures mainly] diuretic detumescent, logical resistance is except yellow, and cold-dispelling pain-relieving, softening the hard mass antiinflammatory, logical urine stimulates the menstrual flow.Cure mainly raw property or private liquid matter disease, as moist edema, yellow cellulitis, paralysis, cold arthralgia, cervical region and axillary lymph tuberculosis, pleuritis, urinary obstruction, under menstruation not.
The present invention compared with prior art, has following beneficial effect:
1, Chinese medicine preparation of the present invention has removing liver heat and toxic substances, soothing liver-QI reaches strongly fragrant, blood circulation promoting and blood stasis dispelling, removing summer-heat is eliminating evil, effect of training spleen reinforcing kidney, and effectively can improve body's immunity.Adjust with Radix Bupleuri in side and reach irritability, the removing summer-heat dampness removings such as Herba Artemisiae Scopariae, Radix Isatidis, Poria, suppress virus; Radix Angelicae Sinensis etc. nourish blood and adjust liver, to expand liver vessel; The strengthening the body resistance such as the Radix Astragali, Fructus Schisandrae Chinensis, enhancing human body immunity function, and the effect that Fructus Cudraniae Cochinchinensis, Radix seu Herba Gymnopteris vestitae etc. have removing food stagnancy eliminating evil, mutually benefit is helped between above-mentioned medical herbs and the ammoniac selected especially, Rabdosia rubescens, Fructus Arctii, all medicines share, not only can receive supplementing QI and nourishing YIN, detoxification and promoting urination, tune liver reason spleen effect, and for prevent disease progress, in invade internal organs also have good preventive effect, very valuable on clinical application.
2, Chinese medicine preparation of the present invention selects high-quality Chinese crude drug to make, and selected medical material compatibility is suitable, meets Chinese medicine and modern medicine study theory, and utilize modern medicine pharmaceutical technology to make, safe without toxic side effect, reach the object for the treatment of both the principal and secondary aspects of a disease, clinic is applied.
Detailed description of the invention
In order to understand better and implement the present invention, further illustrate the present invention below in conjunction with specific embodiment.
Embodiment 1
Treat a Chinese medicine preparation for viral hepatitis, the raw material composition of its effective ingredient and weight are: Fructus Cudraniae Cochinchinensis 9 grams, Radix Bupleuri 13 grams, Herba Artemisiae Scopariae 24 grams, Radix Isatidis 19 grams, Radix Angelicae Sinensis 13 grams, the Radix Astragali 14 grams, Fructus Schisandrae Chinensis 19 grams, Fructus Arctii 10 grams, Rabdosia rubescens 8 grams, Radix seu Herba Gymnopteris vestitae 10 grams, Elettaria cardamomum (L.) Maton 9 grams, Semen Iridis 8 grams, ammoniac 7 grams.
Preparation method, comprises following processing step:
(1) Fructus Cudraniae Cochinchinensis, Radix Bupleuri, Herba Artemisiae Scopariae, Radix Isatidis, Radix Angelicae Sinensis, the Radix Astragali, Fructus Schisandrae Chinensis, Fructus Arctii, Rabdosia rubescens, Radix seu Herba Gymnopteris vestitae, Elettaria cardamomum (L.) Maton, Semen Iridis are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use; (2) ammoniac is put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use; (3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of viral hepatitis of the present invention.
Usage and dosage: oral, every day 1 time, each 1, warm water delivery service after meal; Within 30 days, be 1 course for the treatment of, 2 ~ 3 courses for the treatment of can fully recover.
Embodiment 2
Treat a Chinese medicine preparation for viral hepatitis, the raw material composition of its effective ingredient and weight are: Fructus Cudraniae Cochinchinensis 8 grams, Radix Bupleuri 12 grams, Herba Artemisiae Scopariae 23 grams, Radix Isatidis 18 grams, Radix Angelicae Sinensis 12 grams, the Radix Astragali 13 grams, Fructus Schisandrae Chinensis 18 grams, Fructus Arctii 9 grams, Rabdosia rubescens 7 grams, Radix seu Herba Gymnopteris vestitae 9 grams, Elettaria cardamomum (L.) Maton 8 grams, Semen Iridis 7 grams, ammoniac 6 grams.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
Treat a Chinese medicine preparation for viral hepatitis, the raw material composition of its effective ingredient and weight are: Fructus Cudraniae Cochinchinensis 7 grams, Radix Bupleuri 11 grams, Herba Artemisiae Scopariae 22 grams, Radix Isatidis 17 grams, Radix Angelicae Sinensis 11 grams, the Radix Astragali 12 grams, Fructus Schisandrae Chinensis 17 grams, Fructus Arctii 8 grams, Rabdosia rubescens 6 grams, Radix seu Herba Gymnopteris vestitae 8 grams, Elettaria cardamomum (L.) Maton 7 grams, Semen Iridis 6 grams, ammoniac 5 grams.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
Treat a Chinese medicine preparation for viral hepatitis, the raw material composition of its effective ingredient and weight are: Fructus Cudraniae Cochinchinensis 5 grams, Radix Bupleuri 9 grams, Herba Artemisiae Scopariae 20 grams, Radix Isatidis 15 grams, Radix Angelicae Sinensis 9 grams, the Radix Astragali 10 grams, Fructus Schisandrae Chinensis 15 grams, Fructus Arctii 6 grams, Rabdosia rubescens 4 grams, Radix seu Herba Gymnopteris vestitae 6 grams, Elettaria cardamomum (L.) Maton 5 grams, Semen Iridis 4 grams, ammoniac 3 grams.
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
As the Chinese medicine preparation for the treatment of viral hepatitis, select the routine clinical observation of Patients with Viral Hepatitis 108, patient is divided into treatment group and matched group two groups at random, treatment group 54 example, 4 ~ 62 years old age, 41.5 years old mean age.Matched group 54 example, 3 ~ 68 years old age, 40.8 years old mean age.The course of disease, the degrees of symptoms for the treatment of group and matched group two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes embodiment of the present invention 1-4 either a program gained Chinese medicine preparation, oral, every day 1 time, each 1, warm water delivery service after meal; It within 30 days, is 1 course for the treatment of.2 ~ 3 courses for the treatment of of continuous injection.
Matched group takes lamivudine, and every day, 100mg, 90 days was 1 course for the treatment of, took 2 ~ 3 courses for the treatment of continuously.
3, efficacy determination:
(1) effective: clinical symptoms disappears completely; Hepatosplenomegaly is stablized constant, without kowtowing pain and tenderness, has ascites person's ascites to disappear completely; Liver function recovery is normal.
(2) take a turn for the better: cardinal symptom is clearly better; Hepatosplenomegaly is stablized constant, without obviously kowtowing pain and tenderness, has ascites person's ascites to alleviate more than 50% and do not disappear completely; Liver function index fall is completely abnormal more than 50%.
(3) do not heal: do not reach improvement standard or state of an illness continuation deterioration.
4, result:
Select in the treatment group of Chinese medicine preparation of the present invention, cure 38 examples, take a turn for the better 12 examples, and do not heal 4 examples, cure rate 70.4%, total effective rate 92.6%.
Cure 22 examples in matched group, take a turn for the better 20 examples, and do not heal 12 examples, cure rate 40.7%, total effective rate 77.8%.
Above result display, the cure rate for the treatment of group and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Zhu, man, 42 years old, time medical, liver function continued abnormal, and readme suffers from hepatitis B more than 2 years, and Western medicine diagnosis and treatment do not have obvious curative effects.After taking Chinese medicine preparation of the present invention 30 doses, symptom is clearly better, and after taking 2 courses for the treatment of continuously, liver function recovery is normal, can normally work.
2, Lee, man, 55 years old, time medical, two coerced distending pain, bitter taste and dryness in the mouth, yellow urine constipation, red tongue yellow fur, pulse condition stringy and rapid pulse etc.Viral hepatitis is diagnosed as through checking comprehensively.After taking Chinese medicine preparation of the present invention 30 doses, symptom is clearly better, and after taking 2 courses for the treatment of continuously, liver function recovery is normal, can normally work.
It should be noted that, the above embodiment of the present invention is only for example of the present invention is clearly described, and is not the restriction to embodiments of the present invention.For those of ordinary skill in the field, can also make other changes in different forms on the basis of the above description.Here cannot give exhaustive to all embodiments.Every belong to technical scheme of the present invention the apparent change of extending out or variation be still in the row of protection scope of the present invention.
Claims (5)
1. treat a Chinese medicine preparation for viral hepatitis, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are: Fructus Cudraniae Cochinchinensis 5 ~ 9 parts, Radix Bupleuri 9 ~ 13 parts, Herba Artemisiae Scopariae 20 ~ 24 parts, Radix Isatidis 15 ~ 19 parts, Radix Angelicae Sinensis 9 ~ 13 parts, the Radix Astragali 10 ~ 14 parts, Fructus Schisandrae Chinensis 15 ~ 19 parts, Fructus Arctii 6 ~ 10 parts, Rabdosia rubescens 4 ~ 8 parts, Radix seu Herba Gymnopteris vestitae 6 ~ 10 parts, Elettaria cardamomum (L.) Maton 5 ~ 9 parts, Semen Iridis 4 ~ 8 parts, ammoniac 3 ~ 7 parts.
2. according to a kind of Chinese medicine preparation for the treatment of viral hepatitis described in claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are: Fructus Cudraniae Cochinchinensis 5 ~ 7 parts, Radix Bupleuri 9 ~ 11 parts, Herba Artemisiae Scopariae 20 ~ 22 parts, Radix Isatidis 15 ~ 17 parts, Radix Angelicae Sinensis 9 ~ 11 parts, the Radix Astragali 10 ~ 12 parts, Fructus Schisandrae Chinensis 15 ~ 17 parts, Fructus Arctii 6 ~ 8 parts, Rabdosia rubescens 4 ~ 6 parts, Radix seu Herba Gymnopteris vestitae 6 ~ 8 parts, Elettaria cardamomum (L.) Maton 5 ~ 7 parts, Semen Iridis 4 ~ 6 parts, ammoniac 3 ~ 5 parts.
3. according to a kind of Chinese medicine preparation for the treatment of viral hepatitis described in claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are: Fructus Cudraniae Cochinchinensis 7 parts, Radix Bupleuri 11 parts, Herba Artemisiae Scopariae 22 parts, Radix Isatidis 17 parts, Radix Angelicae Sinensis 11 parts, the Radix Astragali 12 parts, Fructus Schisandrae Chinensis 17 parts, Fructus Arctii 8 parts, Rabdosia rubescens 6 parts, Radix seu Herba Gymnopteris vestitae 8 parts, Elettaria cardamomum (L.) Maton 7 parts, Semen Iridis 6 parts, ammoniac 5 parts.
4. according to a kind of Chinese medicine preparation for the treatment of viral hepatitis described in claim 1, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are: Fructus Cudraniae Cochinchinensis 5 parts, Radix Bupleuri 9 parts, Herba Artemisiae Scopariae 20 parts, Radix Isatidis 15 parts, Radix Angelicae Sinensis 9 parts, the Radix Astragali 10 parts, Fructus Schisandrae Chinensis 15 parts, Fructus Arctii 6 parts, Rabdosia rubescens 4 parts, Radix seu Herba Gymnopteris vestitae 6 parts, Elettaria cardamomum (L.) Maton 5 parts, Semen Iridis 4 parts, ammoniac 3 parts.
5. as described in any one of claim 1 ~ 4, treat a preparation method for the Chinese medicine preparation of viral hepatitis, it is characterized in that: comprise following processing step:
(1) Fructus Cudraniae Cochinchinensis, Radix Bupleuri, Herba Artemisiae Scopariae, Radix Isatidis, Radix Angelicae Sinensis, the Radix Astragali, Fructus Schisandrae Chinensis, Fructus Arctii, Rabdosia rubescens, Radix seu Herba Gymnopteris vestitae, Elettaria cardamomum (L.) Maton, Semen Iridis are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate for subsequent use;
(2) ammoniac is put into container, add strong Chinese liquor, and add a small amount of Mel, stir, through seal of vessel, water proof heating 15 ~ 25min, takes out, obtains mastic for subsequent use;
(3) by the filtrate obtained by above-mentioned steps (1) ~ (2) and mastic mixing, utilize modern advanced pharmacy science and technology, make capsule, obtain the Chinese medicine preparation for the treatment of viral hepatitis of the present invention.
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Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106110212A (en) * | 2016-08-11 | 2016-11-16 | 亳州市益众堂保健食品有限公司 | A kind of Herba Artemisiae Scopariae tea preventing hepatitis and preparation method thereof |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1095283A (en) * | 1993-05-20 | 1994-11-23 | 李永光 | " Sancao " medicine powder for hepatitis B |
CN1233487A (en) * | 1998-04-24 | 1999-11-03 | 汪东平 | Medicine for treating hepatitis B |
CN1559493A (en) * | 2004-02-22 | 2005-01-05 | 通化方大药业股份有限公司 | Medicine for treating hapatitis |
-
2014
- 2014-11-27 CN CN201410691400.1A patent/CN104398961A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1095283A (en) * | 1993-05-20 | 1994-11-23 | 李永光 | " Sancao " medicine powder for hepatitis B |
CN1233487A (en) * | 1998-04-24 | 1999-11-03 | 汪东平 | Medicine for treating hepatitis B |
CN1559493A (en) * | 2004-02-22 | 2005-01-05 | 通化方大药业股份有限公司 | Medicine for treating hapatitis |
Non-Patent Citations (3)
Title |
---|
严艳: "柔肝健脾养阴,活血解毒法治疗慢性乙型肝炎初探", 《中国优秀硕士学位论文全文数据库 医药卫生科技辑》 * |
国家中医药管理局《中华本草》编委会: "《中华本草 维吾尔药卷》", 31 December 2005 * |
奚建英: "护肝片治疗慢性乙型肝炎临床疗效分析", 《现代中西医结合杂志》 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106110212A (en) * | 2016-08-11 | 2016-11-16 | 亳州市益众堂保健食品有限公司 | A kind of Herba Artemisiae Scopariae tea preventing hepatitis and preparation method thereof |
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