CN104398866A - 一种治疗十二指肠溃疡的中药制剂 - Google Patents

一种治疗十二指肠溃疡的中药制剂 Download PDF

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CN104398866A
CN104398866A CN201410580144.9A CN201410580144A CN104398866A CN 104398866 A CN104398866 A CN 104398866A CN 201410580144 A CN201410580144 A CN 201410580144A CN 104398866 A CN104398866 A CN 104398866A
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duodenal ulcer
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万鹏波
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Abstract

本发明公开了一种治疗十二指肠溃疡的中药制剂，属于中药领域。其是由下述重量份的原料药制成：赤小豆10、蒲公英10、千金子8、乌梅10、玉竹8、石榴皮8、乌药6、玫瑰花10、薤白8、小茴香8、积雪草8、草乌叶6、北豆根8、黑芝麻10、太子参10、上茯苓8、竹茹8、紫河车8、厚朴8、莱菔子8、瓦楞子6。本发明采用天然中药为原料，疗效确切且无毒副作用，能有效治愈十二指肠溃疡且不易复发，有效率达97％。

Description

一种治疗十二指肠溃疡的中药制剂
技术领域
本发明涉及一种治疗十二指肠溃疡的中药制剂，属于中药领域。
背景技术
十二指肠溃疡是我国人群中常见病、多发病之一，是消化性溃疡的常见类型，是由于多种因素引起的十二指肠黏膜层和肌层的缺损。好发于气候变化较大的冬春两季。男性发病率明显高于女性。与胃酸分泌异常、幽门螺杆菌(H.pylori)感染、非甾体抗炎药(NSAID)、生活及饮食不规律、工作及外界压力、吸烟、饮酒以及精神心理因素密切相关。主要临床表现为上腹部疼痛，可为钝痛、灼痛、胀痛或剧痛，也可表现为仅在饥饿时隐痛不适。典型者表现为轻度或中度剑突下持续性疼痛，可被制酸剂或进食缓解。
目前，治疗慢性胃炎的方法主要是以西医治疗为主，西医采取抗溃疡与抗幽门螺杆菌药同用，或在溃疡愈合后采用小剂量H2受体拮抗剂维持治疗来降低复发率，但这些药物只能缓解患者病痛，很难根治病患，而且具有一定毒副作用。
发明内容
本发明的目的在于提供一种治疗十二指肠溃疡的中药制剂，该中药制剂疗效确切、见效快且无毒副作用。
本发明的技术方案是：
一种治疗十二指肠溃疡的中药制剂，是由下述重量份的原料药制成：赤小豆10、蒲公英10、千金子8、乌梅10、玉竹8、石榴皮8、乌药6、玫瑰花10、薤白8、小茴香8、积雪草8、草乌叶6、北豆根8、黑芝麻10、太子参10、上茯苓8、竹茹8、紫河车8、厚朴8、莱菔子8、瓦楞子6。
配制及服用方法：水煎服，每日一剂，分早晚两次饭后服用。
各中药的药理作用：
赤小豆：甘、酸，平。归心、小肠经。功效与主治：利水消肿，解毒排脓。用于水肿胀满，脚气肢肿，黄疸尿赤，风湿热痹，痈肿疮毒，肠痈腹痛。
蒲公英：苦、甘，寒。归肝、胃经。功效与主治：清热解毒，消肿散结，利尿通淋。用于疔疮肿毒，乳痈，瘰疬，目赤，咽痛，肺痈，肠痛，湿热黄疸，热淋涩痛。
千金子：辛，温；有毒。归肝、肾、大肠经。功效与主治：逐水消肿，破血消癥。用于水肿，痰饮，积滞胀满，二便不通，血瘀经闭；外治顽癣，疣赘。
乌梅：酸、涩，平。归肝、脾、肺、大肠经。功效与主治：敛肺，涩肠，生津，安蛔。用于肺虚久咳，久痢滑肠，虚热消渴，蛔厥呕吐腹痛；胆道蛔虫症。
玉竹：甘，微寒。归肺、胃经。功效与主治：养阴润燥，生津止渴。用于肺胃阴伤，燥热咳嗽，咽于口渴，内热消渴。
石榴皮：酸、涩，温。归大肠经。功效与主治：涩肠止泻，止血，驱虫。用于久泻、久痢。便血，脱肛，崩漏，白带，虫积腹痛。
乌药：辛，渴。归肺、脾、肾、膀胱经。功效与主治：顺气止痛，温肾散寒。用于胸腹胀痛，气逆喘急，膀胱虚冷，遗尿尿频，疝气，痛经。
玫瑰花：甘、微苦，温。归肝、脾经。功效与主治：行气解郁，和血，止痛。用于肝胃气痛，食少呕恶，月经不调，跌扑伤痛。
薤白：辛、苦，温。归肺、胃、大肠经。功效与主治：通阳散结，行气导滞。用于胸痹疼痛，痰饮咳喘，泄痢后重。
小茴香：辛，温。归肝、肾、脾、胃经。功效与主治：散寒止痛，理气和胃。用于寒疝腹痛，睾丸偏坠，痛经，少腹冷痛，院腹胀痛，食少吐泻，睾丸鞘膜积液。盐小茴香暖肾散寒止痛。用于寒疝腹痛，睾丸偏坠，经寒腹痛。
积雪草：苦、辛，寒。归肝、脾、肾经。功效与主治：清热利湿，解毒消肿。用于湿热黄疸，中暑腹泻，砂淋血淋，痈肿疮毒，跌扑损伤。
草乌叶：辛、涩，平；有小毒。功效与主治：清热，解毒，止痛。用于热病发热，泄泻腹痛，头痛，牙痛。
北豆根：苦，寒；有小毒。归肺、胃、大肠经。功效与主治：清热解毒，祛风止痛。用于咽喉肿痛，肠炎痢疾，风湿痹痛。
黑芝麻：甘，平。归肝、肾、大肠经。功效与主治：补肝肾，益精血，润肠燥。用于头晕眼花，耳鸣耳聋，须发早白，病后脱发.肠燥便秘。
太子参：甘、微苦，平。归脾、肺经。功效与主治：益气健脾，生津润肺。用于脾虚体倦，食欲不振，病后虚弱，气阴不足，自汗口渴，肺燥干咳。
上茯苓：甘、淡，平。归肝、胃经。功效与主治：除湿，解毒，通利关节。用于湿热淋浊，带下，痈肿，瘰病，疥癣，梅毒及汞中毒所致的肢体拘挛，筋骨疼痛。
竹茹：甘，微寒。归肺、胃经。功效与主治：清热化痰，除烦止呕。用于痰热咳嗽，胆火挟痰，烦热呕吐，惊悸失眠，中风痰迷，舌强不语，胃热呕吐，妊娠恶阻，胎动不安。
紫河车：甘、咸，温。归心、肺、肾经。功效与主治：温肾补精，益气养血。用于虚劳赢瘦，骨蒸盗汗，咳嗽气喘，食少气短，阳痿遗精，不孕少乳。
厚朴：苦、辛，温。归脾、胃、肺、大肠经。功效与主治：燥湿消痰，下气除满。用于湿滞伤中，脘痞吐泻，食积气滞，腹胀便秘，痰饮喘咳。
莱菔子：辛、甘，平。归肺、脾、胃经。功效与主治：消食除胀，降气化痰。用于饮食停滞，脘腹胀痛，大便秘结，积滞泻痢，痰壅喘咳。
瓦楞子：咸，平。归肺、胃、肝经。功效与主治：消痰化瘀，软坚散结，制酸止痛。用于顽痰积结，黏稠难咯，瘿瘤，瘰疬，癥瘕痞块，胃痛泛酸。
本发明的有益效果是：本发明采用天然中药为原料，疗效确切且无毒副作用，能有效治愈十二指肠溃疡且不易复发，有效率达97％。
以下结合临床试验对本发明进一步说明。
一、临床试验
1、临床资料：2012年6月至2014年6月两年间，共观察22-59岁的十二指肠溃疡患者100例，其平均年龄为33.5岁。
2、诊断标准：(1)长期反复发作的周期性、节律性慢性上腹部疼痛；(2)上腹部有局限性深在压痛；(3)X线钡餐造影见溃疡龛影；(4)内窥镜镜检可见到活动期溃疡。
3、治疗方法：其中治疗组服用本发明中药，水煎服，每日一剂，分早晚两次饭后服用，3天为1个疗程。
4、疗效判定标准：
痊愈：主要症状与次要症状全部消失，胃镜检查溃疡完全消失，局部轻度充血，但无明显水肿；
有效：主症与次症均有明显改善，胃镜检查溃疡面缩小50％以上；
无效：主症与次症均无改善，胃镜检查溃疡面缩小不及50％。
5、治疗结果：在临床使用本发明药物，服药的100例患者，服药1个疗程后，症状明显缓解，继续服药2个疗程后，痊愈82例，有效15例，总有效率为97％。
具体实施方式
实施例1
配比(单位：重量份)：
赤小豆10、蒲公英10、千金子8、乌梅10、玉竹8、石榴皮8、乌药6、玫瑰花10、薤白8、小茴香8、积雪草8、草乌叶6、北豆根8、黑芝麻10、太子参10、上茯苓8、竹茹8、紫河车8、厚朴8、莱菔子8、瓦楞子6。
配制及服用方法：水煎服，每日一剂，分早晚两次饭后服用。

Claims (1)

1.一种治疗十二指肠溃疡的中药制剂，其特征在于，是由下述重量份的原料药制成：赤小豆10、蒲公英10、千金子8、乌梅10、玉竹8、石榴皮8、乌药6、玫瑰花10、薤白8、小茴香8、积雪草8、草乌叶6、北豆根8、黑芝麻10、太子参10、上茯苓8、竹茹8、紫河车8、厚朴8、莱菔子8、瓦楞子6。
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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1785359A (zh) * 2005-08-03 2006-06-14 蔡青 一种治疗胃肠病的中药制剂
CN101081289A (zh) * 2007-04-13 2007-12-05 唐奎芳 奇仙消胀胃痛灵
CN103041280A (zh) * 2013-01-22 2013-04-17 陈振卯 一种消炎、止泻、止痛的复方中药

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1785359A (zh) * 2005-08-03 2006-06-14 蔡青 一种治疗胃肠病的中药制剂
CN101081289A (zh) * 2007-04-13 2007-12-05 唐奎芳 奇仙消胀胃痛灵
CN103041280A (zh) * 2013-01-22 2013-04-17 陈振卯 一种消炎、止泻、止痛的复方中药

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