CN104398837A - Prickly-heat powder for treating miliaria rubra - Google Patents
Prickly-heat powder for treating miliaria rubra Download PDFInfo
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- CN104398837A CN104398837A CN201410630396.8A CN201410630396A CN104398837A CN 104398837 A CN104398837 A CN 104398837A CN 201410630396 A CN201410630396 A CN 201410630396A CN 104398837 A CN104398837 A CN 104398837A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/355—Lonicera (honeysuckle)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention relates to the field of traditional Chinese medicine composition, and more specifically relates to a prickly-heat powder for treating miliaria rubra. The powder is composed of the following components: borneol, honeysuckle flower, cortex lycii, lotus leaf, purslane, poria cocos, potentilla discolor, safflower, cordate houttuynia, dendrobium, andrographis paniculata, oriental waterplantain rhizome, sambucus chinensis, licorice, dwarf lilyturf tuber, Chinese pulsatilla root, and Japanese honeysuckle stem. The prickly-heat powder has a quick effect, can relieve the itching within 24 hours, and is capable of curing the patients in 3 to 7 days. The cure rate in three days is 57.91%, and the effective rate is 41.67% in three days. The cure rate can reach 96.67% after 7 days, and the total effective rate is 100%.
Description
Technical field
The present invention relates to Chinese medicine composition field, more specifically a kind of prickly-heat powder being used for the treatment of red miliaria.
Background technology
Miliaria is the shallow property of table, inflammatory dermatoses common under summer or hot environment, because temperature in environment is high, high humidity, excessive sweating, not easily evaporate, perspiration makes horny layer of epidermis flood, cause sudoriferous duct mouth narrow or block, break in sudoriferous duct after perspiration retention because of intrinsic pressure increasing, excessive perspiration infiltrates and stimulates surrounding tissue and occur pimple, papulovesicle and phlysis in pore place.Bacterial reproduction, generation toxin, can exacerbate inflammation reaction.Someone thinks, the obturation of pore is due to constitutional staphy lococcus infection, and also someone thinks that the generation of miliaria and excessive sweating have nothing to do, and relevant with the prolific micrococcus luteus of skin surface.
Overflow the difference at position according to sudoriferous duct damage and perspiration, be divided into following several types clinically:
1. miliaria crystallina
Also known as miliaria alba, due to perspiration in horny layer or under horny layer antiperspirant pipe overflow cause.Be common in a large amount of perspiration of high heat, long-term bed, excessively weak patient.Skin lesion is needle point extremely pinhead-sized shallow phlysis, and wall is thin, limpid, around without blush, dabs easily broken, leaves tiny squama after dry.There is self limiting, general no conscious sympton.
2. miliaria rubra
Also known as red miliaria, because perspiration causes in spinous layer place antiperspirant pipe spilling.Acute onset, skin lesion is occur round and pointed pinhead-sized intensive pimple or papulovesicle in batch, has slight blush around.Slight desquamation is had after skin lesion disappears.Consciously slightly to burn, prodding and itching feeling.
3. miliaria pustulosa
Also known as pus miliaria.How to be developed by miliaria rubra.Skin lesion is that intensive papular top has the shallow table pustule of syringe needle size.Pustule content is often aseptic or nonpathogenic cocci.
4. miliaria profunda
Also known as dark miliaria, because perspiration particularly causes in corium-epidermal junction antiperspirant pipe spilling at dermis.Be common in the patient that miliaria rubra occurs seriously and repeatedly.Skin lesion is intensive color of the leather phlysis, and content is limpid, not easily frays, and increases during perspiration, reduces when not perspiring.When general of erythra, whole skin is perspired and to be reduced or lossless, and face, axillary fossa, brothers can have compensatory sweating to increase, and can cause tropical anhidrosis sexual exhaustion or heat exhaustion, and the General Symptomies such as unable, sleepy, dizzy, headache can appear in patient.
And the probability that child obtains miliaria is greater than adult, because miliaria is very itched hard to bear, cause the declines such as patient's appetite, have a strong impact on the life of patient, the Therapeutic Method of current most convenient is namely to affected part coating prickly-heat powder, but the wide variety of current miliaria, and also the kind of prickly-heat powder is numerous and diverse especially, therefore how patient selects suitable prickly-heat powder to become difficulty, is more than weak point of the prior art.
Summary of the invention
Goal of the invention of the present invention is for deficiency of the prior art, provides the prickly-heat powder being applicable to red miliaria that a kind of instant effect, therapeutic effect are good.
The present invention is achieved by the following technical solutions:
Be used for the treatment of a prickly-heat powder for red miliaria, be made up of following component: Borneolum Syntheticum, Flos Lonicerae, Cortex Lycii, Folium Nelumbinis, Herba Portulacae, Poria, Herba Potentillae Discoloris, Flos Carthami, Herba Houttuyniae, Herba Dendrobii, Herba Andrographis, Rhizoma Alismatis, Herba Sambuci Chiensis, Radix Glycyrrhizae, Radix Ophiopogonis door, the Radix Pulsatillae, Caulis Lonicerae.
Above-mentioned a kind of prickly-heat powder being used for the treatment of red miliaria, is made up of following component by weight: Borneolum Syntheticum 2-6 part, Flos Lonicerae 10-15 part, Cortex Lycii 2-6 part, Folium Nelumbinis 2-6 part, Herba Portulacae 5-10 part, Poria 2-6 part, Herba Potentillae Discoloris 5-10 part, Flos Carthami 5-10 part, Herba Houttuyniae 2-6 part, Herba Dendrobii 2-6 part, Herba Andrographis 5-10 part, Rhizoma Alismatis 2-6 part, Herba Sambuci Chiensis 2-6 part, Radix Glycyrrhizae 2-6 part, Radix Ophiopogonis door 2-6 part, Radix Pulsatillae 2-6 part, Caulis Lonicerae 2-6 part.
Above-mentioned a kind of prickly-heat powder being used for the treatment of red miliaria, is made up of following component by weight: Borneolum Syntheticum 3 parts, Flos Lonicerae 12 parts, Cortex Lycii 3 parts, 3 parts, Folium Nelumbinis, Herba Portulacae 6 parts, 3 parts, Poria, Herba Potentillae Discoloris 6 parts, 6 parts, Flos Carthami, Herba Houttuyniae 3 parts, Herba Dendrobii 3 parts, Herba Andrographis 6 parts, Rhizoma Alismatis 3 parts, Herba Sambuci Chiensis 3 parts, 3 parts, Radix Glycyrrhizae, Radix Ophiopogonis 3 parts, door, the Radix Pulsatillae 3 parts, Caulis Lonicerae 3 parts.
Above-mentioned a kind of prickly-heat powder being used for the treatment of red miliaria, is made up of following component by weight: Borneolum Syntheticum 5 parts, Flos Lonicerae 14 parts, Cortex Lycii 4 parts, 4 parts, Folium Nelumbinis, Herba Portulacae 8 parts, 4 parts, Poria, Herba Potentillae Discoloris 8 parts, 8 parts, Flos Carthami, Herba Houttuyniae 4 parts, Herba Dendrobii 4 parts, Herba Andrographis 8 parts, Rhizoma Alismatis 4 parts, Herba Sambuci Chiensis 4 parts, 4 parts, Radix Glycyrrhizae, Radix Ophiopogonis 4 parts, door, the Radix Pulsatillae 4 parts, Caulis Lonicerae 4 parts.
Above-mentioned a kind of preparation method being used for the treatment of the prickly-heat powder of red miliaria, comprise the steps: Borneolum Syntheticum, Flos Lonicerae, Cortex Lycii, Folium Nelumbinis, Herba Portulacae, Poria, Herba Potentillae Discoloris, Flos Carthami, Herba Houttuyniae, Herba Dendrobii, Herba Andrographis, Rhizoma Alismatis, Herba Sambuci Chiensis, Radix Glycyrrhizae, Radix Ophiopogonis door, the Radix Pulsatillae, Caulis Lonicerae decocts with water extraction three times, first time adds the water boiling and extraction 2 hours of Chinese medicinal components gross mass 5 times, second time adds Chinese medicinal components gross mass 3 times amount water boiling and extraction 1.5 hours, third time adds Chinese medicinal components gross mass 2 times amount water boiling and extraction 1 hour, 3 times are decocted the decocting liquid extracted to merge, in the decocting liquid after merging, add the aqueous solution after above-mentioned distillation, filter, it is 1.07 ~ 1.10 that filtrate is concentrated into relative density 60 DEG C time, lets cool to room temperature, adds ethanol and reach 60% to alcohol content, stir evenly, at 6 ~ 9 DEG C, leave standstill 24 hours, filters, it is 1.07 ~ 1.10 that filtrate is concentrated into relative density 60 DEG C time, and reclaims ethanol in concentration process, then add with concentrated after filtrate isopyknic water dilute, stir evenly, leave standstill lower 24 hours at 6 ~ 9 DEG C, filtration, put into drying baker after adding hot filtrate to pasty state to dry, pulverize after cooling.
Clinical trial
Using method
The article of swab stick or other clean hygienes are used prickly-heat powder of the present invention to be applied to affected part, uniform fold, every day 1-2 time.
Therapeutic effect
Cure: antipruritic, skin recovers normal; Effective: substantially antipruritic, skin is necessarily recovered; Invalid: the symptoms such as skin pruritus are without improvement.
Therapeutic effect
Case 240 people, wherein less than 10 years old 33 people, 11-20 year 62 people, 21-30 year 85 people, 31-40 year 33 people, 41-50 year 19 people, more than 51 years old 8 people.Treatment antipruritic person 226 people on the same day, treat 3 days healing person 139 people, account for 57.91%, effective person 100 people, accounts for 41.67%, nonresponder 1 people, and 7 days healing person 232 people, account for 96.67%, effective person 8 people, nonresponder 0 people.
Model case
1, Zhang, man, 10 years old, miliaria was more and be evident as red miliaria, and treatment was antipruritic for the same day, within 3 days, cured;
2, Liu, man, 39 miliarias are more and be evident as red miliaria, antipruritic for the same day with a small amount of blush treatment, within 3 days, cure;
3, Zhao, female 55, and forehead, back cover with miliaria, are evident as red miliaria, and treatment was effective for the same day, recovery from illness in 7 days;
The invention has the beneficial effects as follows: prickly-heat powder instant effect of the present invention, the same day can be antipruritic, and recovery from illness in 3-7 days, wherein 3 days healing persons 57.91%, effective person 41.67%, 7 days healing persons reach 96.67%, total effective rate 100%.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described, so that those skilled in the art better can understand the present invention, but therefore do not limit the present invention.
Embodiment 1
Be used for the treatment of a prickly-heat powder for red miliaria, be made up of following component by weight: Borneolum Syntheticum 2 parts, Flos Lonicerae 10 parts, Cortex Lycii 2 parts, 2 parts, Folium Nelumbinis, Herba Portulacae 5 parts, 2 parts, Poria, Herba Potentillae Discoloris 5 parts, 5 parts, Flos Carthami, Herba Houttuyniae 2 parts, Herba Dendrobii 2 parts, Herba Andrographis 5 parts, Rhizoma Alismatis 2 parts, Herba Sambuci Chiensis 2 parts, 2 parts, Radix Glycyrrhizae, Radix Ophiopogonis 6 parts, door, the Radix Pulsatillae 2 parts, Caulis Lonicerae 2 parts.
Embodiment 2
Be used for the treatment of a prickly-heat powder for red miliaria, be made up of following component by weight: Borneolum Syntheticum 3 parts, Flos Lonicerae 12 parts, Cortex Lycii 3 parts, 3 parts, Folium Nelumbinis, Herba Portulacae 6 parts, 3 parts, Poria, Herba Potentillae Discoloris 6 parts, 6 parts, Flos Carthami, Herba Houttuyniae 3 parts, Herba Dendrobii 3 parts, Herba Andrographis 6 parts, Rhizoma Alismatis 3 parts, Herba Sambuci Chiensis 3 parts, 3 parts, Radix Glycyrrhizae, Radix Ophiopogonis 3 parts, door, the Radix Pulsatillae 3 parts, Caulis Lonicerae 3 parts.
Embodiment 3
Be used for the treatment of a prickly-heat powder for red miliaria, be made up of following component by weight: Borneolum Syntheticum 5 parts, Flos Lonicerae 14 parts, Cortex Lycii 4 parts, 4 parts, Folium Nelumbinis, Herba Portulacae 8 parts, 4 parts, Poria, Herba Potentillae Discoloris 8 parts, 8 parts, Flos Carthami, Herba Houttuyniae 4 parts, Herba Dendrobii 4 parts, Herba Andrographis 8 parts, Rhizoma Alismatis 4 parts, Herba Sambuci Chiensis 4 parts, 4 parts, Radix Glycyrrhizae, Radix Ophiopogonis 4 parts, door, the Radix Pulsatillae 4 parts, Caulis Lonicerae 4 parts.
Embodiment 4
Be used for the treatment of a prickly-heat powder for red miliaria, be made up of following component by weight: Borneolum Syntheticum 6 parts, Flos Lonicerae 15 parts, Cortex Lycii 6 parts, lotus 6 parts, Herba Portulacae 10 parts, 6 parts, Poria, Herba Potentillae Discoloris 10 parts, 10 parts, Flos Carthami, Herba Houttuyniae 6 parts, Herba Dendrobii 6 parts, Herba Andrographis 10 parts, Rhizoma Alismatis 6 parts, Herba Sambuci Chiensis 6 parts, 6 parts, Radix Glycyrrhizae, Radix Ophiopogonis 6 parts, door, the Radix Pulsatillae 6 parts, Caulis Lonicerae 6 parts.
Claims (5)
1. be used for the treatment of a prickly-heat powder for red miliaria, be made up of following component: Borneolum Syntheticum, Flos Lonicerae, Cortex Lycii, Folium Nelumbinis, Herba Portulacae, Poria, Herba Potentillae Discoloris, Flos Carthami, Herba Houttuyniae, Herba Dendrobii, Herba Andrographis, Rhizoma Alismatis, Herba Sambuci Chiensis, Radix Glycyrrhizae, Radix Ophiopogonis door, the Radix Pulsatillae, Caulis Lonicerae.
2. a kind of prickly-heat powder being used for the treatment of red miliaria according to claim 1, is characterized in that: be made up of following component by weight: Borneolum Syntheticum 2-6 part, Flos Lonicerae 10-15 part, Cortex Lycii 2-6 part, Folium Nelumbinis 2-6 part, Herba Portulacae 5-10 part, Poria 2-6 part, Herba Potentillae Discoloris 5-10 part, Flos Carthami 5-10 part, Herba Houttuyniae 2-6 part, Herba Dendrobii 2-6 part, Herba Andrographis 5-10 part, Rhizoma Alismatis 2-6 part, Herba Sambuci Chiensis 2-6 part, Radix Glycyrrhizae 2-6 part, Radix Ophiopogonis door 2-6 part, Radix Pulsatillae 2-6 part, Caulis Lonicerae 2-6 part.
3. a kind of prickly-heat powder being used for the treatment of red miliaria according to claim 2, is characterized in that: be made up of following component by weight: Borneolum Syntheticum 3 parts, Flos Lonicerae 12 parts, Cortex Lycii 3 parts, 3 parts, Folium Nelumbinis, Herba Portulacae 6 parts, 3 parts, Poria, Herba Potentillae Discoloris 6 parts, 6 parts, Flos Carthami, Herba Houttuyniae 3 parts, Herba Dendrobii 3 parts, Herba Andrographis 6 parts, Rhizoma Alismatis 3 parts, Herba Sambuci Chiensis 3 parts, 3 parts, Radix Glycyrrhizae, Radix Ophiopogonis 3 parts, door, the Radix Pulsatillae 3 parts, Caulis Lonicerae 3 parts.
4. a kind of prickly-heat powder being used for the treatment of red miliaria according to claim 2, is characterized in that: be made up of following component by weight: Borneolum Syntheticum 5 parts, Flos Lonicerae 14 parts, Cortex Lycii 4 parts, 4 parts, Folium Nelumbinis, Herba Portulacae 8 parts, 4 parts, Poria, Herba Potentillae Discoloris 8 parts, 8 parts, Flos Carthami, Herba Houttuyniae 4 parts, Herba Dendrobii 4 parts, Herba Andrographis 8 parts, Rhizoma Alismatis 4 parts, Herba Sambuci Chiensis 4 parts, 4 parts, Radix Glycyrrhizae, Radix Ophiopogonis 4 parts, door, the Radix Pulsatillae 4 parts, Caulis Lonicerae 4 parts.
5. a kind of preparation method being used for the treatment of the prickly-heat powder of red miliaria according to claim 1, comprise the steps: Borneolum Syntheticum, Flos Lonicerae, Cortex Lycii, Folium Nelumbinis, Herba Portulacae, Poria, Herba Potentillae Discoloris, Flos Carthami, Herba Houttuyniae, Herba Dendrobii, Herba Andrographis, Rhizoma Alismatis, Herba Sambuci Chiensis, Radix Glycyrrhizae, Radix Ophiopogonis door, the Radix Pulsatillae, Caulis Lonicerae decocts with water extraction three times, first time adds the water boiling and extraction 2 hours of Chinese medicinal components gross mass 5 times, second time adds Chinese medicinal components gross mass 3 times amount water boiling and extraction 1.5 hours, third time adds Chinese medicinal components gross mass 2 times amount water boiling and extraction 1 hour, 3 times are decocted the decocting liquid extracted to merge, in the decocting liquid after merging, add the aqueous solution after above-mentioned distillation, filter, it is 1.07 ~ 1.10 that filtrate is concentrated into relative density 60 DEG C time, lets cool to room temperature, adds ethanol and reach 60% to alcohol content, stir evenly, at 6 ~ 9 DEG C, leave standstill 24 hours, filters, it is 1.07 ~ 1.10 that filtrate is concentrated into relative density 60 DEG C time, and reclaims ethanol in concentration process, then add with concentrated after filtrate isopyknic water dilute, stir evenly, leave standstill lower 24 hours at 6 ~ 9 DEG C, filtration, put into drying baker after adding hot filtrate to pasty state to dry, pulverize after cooling.
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