CN104383423B - A kind of Chinese medicine for treating sitophobia disease - Google Patents

A kind of Chinese medicine for treating sitophobia disease Download PDF

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Publication number
CN104383423B
CN104383423B CN201410750320.9A CN201410750320A CN104383423B CN 104383423 B CN104383423 B CN 104383423B CN 201410750320 A CN201410750320 A CN 201410750320A CN 104383423 B CN104383423 B CN 104383423B
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medicine
decoction liquor
cooked
sitophobia
slow fire
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CN104383423A (en
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黄可丹
王雅丽
刘湘花
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Henan University of Traditional Chinese Medicine HUTCM
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Henan University of Traditional Chinese Medicine HUTCM
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Abstract

The present invention relates to the Chinese medicine for the treatment of sitophobia disease, effectively solve that children sitophobia disease treatment cycle is long, effect is poor, easily repeatedly the problem of, by by weight:The 10g of Radix Codonopsis 8, the 13g of Chinese yam 11, the 7g of fructus amomi 5, the 13g of coix seed 11, the 13g of the membrane of a chicken's gizzard 11, the 10g of Fructus Aurantii 8, the 13g of the bighead atractylodes rhizome 11, the 10g of Poria cocos 8, the 10g of dried orange peel 8, the 13g of coloured malt 11, the 13g of hawthorn 11, the 13g of Divine Comedy 11, the 13g of oyster 11, the 10g of pangolin 8 and the 10g of tortoiseshell 8 are made as material medicine, above-mentioned raw materials medicine is mixed, add water to submerge material medicine, decoct, first boil with high heat, again with being cooked by slow fire, filter, obtain first time decoction liquor;The dregs of a decoction are added water to submerge, and are boiled by intense fire, then with being cooked by slow fire, are filtered, and are obtained second of decoction liquor, are merged decoction liquor twice, produce, compatibility science of the present invention, method is simple, and treatment cycle is short, and effect is good, not repeatedly, has no side effect, and are the big creation on traditional Chinese medicine.

Description

A kind of Chinese medicine for treating sitophobia disease
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of Chinese medicine for treating sitophobia disease.
Background technology
Children's sitophobia disease refers to longer anorexia or disappearance, and appetite is reduced to for cardinal symptom.Main disease Shape has vomiting, anorexia, diarrhoea, constipation, abdominal distension, suffers from abdominal pain and have blood in stool.Serious children's sitophobia can cause children growth to be sent out Educate, height, body weight are below normal children of same age average level.It is most common to be caused by poor eating habits, with bad drink Food structure, it is particular about food, do not eat that vegetables, happiness before meals eat the snacks such as candy and the reason such as not timing of having a meal is relevant.Recently as micro- The detection of secondary element and the understanding of effect are goed deep into, and find the food of zinc-deficiency, many of which trace element, it is necessary to and it is nonessential , when each trace element amount of daily intaking is less than excretion, organism is the trace element stored in vivo by employing Method compensate, under so-called " negative balance " state, remain to maintain needs by a long duration, but end can lack Weary state.
Zinc is a kind of the essential trace elements of the human body, is also intracellular most abundant trace element.Normal person's in-vivo content About the 0.0033% of percentage of liveweight, is 2~2.5g.Adult needs 10~15mg/d, and children about need 10mg/d.Zinc be distributed in human body each In histoorgan, at most, pancreas, liver, kidney, muscle also contain more zinc to the organ such as retina, choroid, prostate content.
Zinc-deficiency refers to that body zinc level or zinc reserves can not meet the state of physiological requirements amount.Zinc-deficiency often causes mucous membrane of mouth Hyperplasia and dyskeratosis, epithelial cell are easy to come off and cover and block taste bud aperture, make taste function low, then reduction food It is intended to;On the other hand make the zinc enzyme activity reduction of nucleic acid and protein metabolism needs, cause the obstacle of taste bud 26S Proteasome Structure and Function, make Taste function is further reduced, fungiform papillae of tongue hypertrophy or atrophy;Zinc-deficiency reduces carboxyl phthalein enzyme A vigor, makes digestive function Substantially reduction.
The children's sitophobia disease caused at present for this zinc-deficiency, therapeutic scheme is varied, but can not fundamentally treat Children's sitophobia disease, some are only to rely on simple zinc supplementation, the symptom for suffering from the digestive discomfort triggered after children's sitophobia disease, and Do not obtain the effective treatment, and the cycle is long, effect is poor, easily repeatedly.
The content of the invention
For above-mentioned situation, to overcome prior art defect, the purpose of the present invention, which is just to provide, a kind of treats sitophobia disease Chinese medicine, can effectively solve that children's sitophobia disease treatment cycle is long, and effect is poor, easily repeatedly the problem of.
The technical scheme that the present invention is solved is, by by weight:Radix Codonopsis 8-10g, Chinese yam 11-13g, fructus amomi 5-7g, the heart of a lotus seed Seed of jog's tears 11-13g, the membrane of a chicken's gizzard 11-13g, Fructus Aurantii 8-10g, bighead atractylodes rhizome 11-13g, Poria cocos 8-10g, dried orange peel 8-10g, coloured malt 11- 13g, hawthorn 11-13g, Divine Comedy 11-13g, oyster 11-13g, pangolin 8-10g and tortoiseshell 8-10g are made as material medicine, its In, above-mentioned raw materials medicine is mixed, material medicine is added water to submerge, decocted, is first boiled with high heat, then with being cooked by slow fire 30-40 minutes, Filtering, obtains first time decoction liquor;The dregs of a decoction are added water to submerge, and are boiled by intense fire, then with being cooked by slow fire 20-30 minutes, are filtered, and are obtained second and are decocted Boil liquid, merges decoction liquor twice, produces.
Compatibility science of the present invention, method is simple, and treatment cycle is short, and effect is good, not repeatedly, has no side effect, and is on traditional Chinese medicine One big create.
Embodiment
The embodiment to the present invention elaborates with reference to embodiments.
Embodiment 1
The present invention is by following weight meter:Radix Codonopsis 8g, Chinese yam 11g, fructus amomi 5g, coix seed 11g, the membrane of a chicken's gizzard 11g, Fructus Aurantii 8g, bighead atractylodes rhizome 11g, Poria cocos 8g, dried orange peel 8-10g, coloured malt 11g, hawthorn 11g, Divine Comedy 11g, oyster 11g, pangolin 8g and tortoiseshell 8g is made as material medicine, wherein, above-mentioned raw materials medicine is mixed, material medicine is added water to submerge, decocted, is first boiled with high heat, Again with being cooked by slow fire 30 minutes, filter, obtain first time decoction liquor;The dregs of a decoction are added water to submerge, and are boiled by intense fire, then with being cooked by slow fire 20 minutes, Filtering, obtains second of decoction liquor, merges decoction liquor twice, produces.
Embodiment 2
The present invention is by following weight meter:Radix Codonopsis 9g, Chinese yam 12g, fructus amomi 6g, coix seed 12g, the membrane of a chicken's gizzard 12g, Fructus Aurantii 9g, bighead atractylodes rhizome 12g, Poria cocos 9g, dried orange peel 9g, coloured malt 12g, hawthorn 12g, Divine Comedy 12g, oyster 12g, pangolin 9g and tortoiseshell 9g make Material medicine is made, wherein, above-mentioned raw materials medicine is mixed, material medicine is added water to submerge, decocted, is first boiled with high heat, then use It is cooked by slow fire 35 minutes, filters, obtain first time decoction liquor;The dregs of a decoction are added water to submerge, and are boiled by intense fire, then with being cooked by slow fire 25 minutes, are filtered, Second of decoction liquor is obtained, merges decoction liquor twice, produces.
Embodiment 3
The present invention is by following weight meter:Radix Codonopsis 10g, Chinese yam 13g, fructus amomi 7g, coix seed 13g, the membrane of a chicken's gizzard 13g, Fructus Aurantii 10g, bighead atractylodes rhizome 13g, Poria cocos 10g, dried orange peel 10g, coloured malt 13g, hawthorn 13g, Divine Comedy 13g, oyster 13g, pangolin 10g and tortoiseshell 10g is made as material medicine, wherein, above-mentioned raw materials medicine is mixed, material medicine is added water to submerge, decocted, is first boiled with high heat, Again with being cooked by slow fire 40 minutes, filter, obtain first time decoction liquor;The dregs of a decoction are added water to submerge, and are boiled by intense fire, then with being cooked by slow fire 30 minutes, Filtering, obtains second of decoction liquor, merges decoction liquor twice, produces.
Medicine described above, wherein:
Radix Codonopsis:Impurity is removed, is cleaned, is run through, cut sheet, is dried.Strengthening spleen and tonifying lung, nourishes blood and promotes the production of body fluid, for spleen-lung Qi deficiency, food Few burnout, false asthma cough, insufficiency of vital energy and blood, sallow complexion, palpitation, injury thirst, Heat Diabetes.
Chinese yam:Size is separated, is cleaned, tertia is scraped off, bubble profit is cut sheet to saturating, dried.Tonifying spleen nourishing the stomach, engender liquid and benefic lung, For spleen eating less, endless diarrhea, the deficiency syndrome of the lung is breathed with cough, and frequent micturition, abnormal heat is quenched one's thirst.
Fructus amomi:Decontamination, is dried, and is smashed.Promoting the circulation of qi middle benefit gas, and stomach, are amusing, and control stomachache swollen ruffian, and loss of appetite food stagnation is dysphagic to vomit Tell, it is cold to rush down cold dysentery.
Coix seed:Dry, except decapsidate and kind skin, sharp water penetration is wet, invigorating the spleen to arrest diarrhea, eliminating impediment, detoxicating and resolving a mass, for water It is swollen, tinea pedis, difficult urination, splenasthenic diarrhea, arthritis with fixed pain caused by dampness contraction.
The membrane of a chicken's gizzard:Clean, dry, grind.Stomach strengthening and digestion promoting, changes hard niter.For dyspepsia, vomiting dysentery, children's infantile malnutrition due to digestive disturbances or intestinalparasites Product, the enuresis, the puckery pain of urolithiasis, hypochondriac pain that courage is swollen.
Fructus Aurantii:Weeded out after drying it is broken fall flesh core.Regulating the flow of QI to ease the stomach, the stagnant dissipate-swelling of row, for the chest side of body stagnation of the circulation of vital energy, turgor pain, food Product is not changed, and stops in phlegm and retained fluid, visceral organ ptosis.
The bighead atractylodes rhizome:Impurity is removed, is cleaned, is run through, cut sheet, is dried.Strengthening the spleen and replenishing qi, eliminate dampness and have diuretic effect, hidroschesis, for insufficiency of the spleen food It is few, abdominal distention diarrhea, phlegm retention anti-dazzle nervous, oedema, spontaneous perspiration.
Poria cocos:Dry in the air to dry tack free, cutting is blocking or cuts sheet.Clearing damp and promoting diuresis, invigorating the spleen, calming heart, for oedema oliguria, phlegm Drink feel dizzy and heart palpitations, spleen eating less, loose stool diarrhea, confused and worried, insomnia of palpitating with fear.
Dried orange peel:Impurity is removed, shower water is run through, chopping, dried, regulating qi-flowing for strengthening spleen is eliminating dampness and eliminating phlegm, for abdominal fullness and distention, food It is few to vomit and diarrhoea, coughing with a lot of sputum.
Coloured malt:Net malt is taken, slow fire in pot is put and fries to brown color, cool, weed out grey bits, promoting the circulation of qi helps digestion, spleen benefiting and stimulating the appetite. For dyspepsia, abdominal distention, spleen eating less, stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach.
Hawthorn:Impurity and the core come off are removed, food digesting stomach fortifying, scattered stasis changes turbid lipid-loweringing, for meat stagnation, gastral cavilty Turgor, diarrhea dysentery abdominal pain, confidant sting, chest impediment and cardialgia, hernia pain.
Divine Comedy:Promoting digestion and removing indigestion, strengthening the spleen and stomach, inducing diaphoresis.Flu food stagnation, epigastric distension and distress, indigestion, diarrhoea are cured mainly, arrogates to oneself and disappears Starch, melon and fruit class stagnate.
Oyster:Cleaning, drying, pulverize, transquilization with heavy material, checking exuberance of yang tonifying yin, softening and resolving hard mass, for insomnia of palpitating with fear, dizziness and tinnitus, Scrofula subcutaneous nodule , abdominal lump of mass in abdomen.
Pangolin:Scale and shell is collected, cleans, dries, activating blood to eliminate diseases, detumescence and apocenosis search wind and removing obstruction in channels, for carbuncle sore tumefacting virus, wind Arthritis with fixed pain caused by dampness pain, numbness contracture.
Tortoiseshell:Clean and dry, smash to pieces, control the deficiency of the kidney yin, hectic fever due to yin labor heat is spitted blood, bleeding from five sense organs or subcutaneous tissue, chronic cough, the atrophic debility of bones, wind formation from yin deficiency, Protracted dysentery, chronic malaria, hemorrhoid.
From said medicine, all medicine phases 5 of the invention, with invigorating the spleen, stomach, softening and resolving hard mass, effect of promoting the circulation of qi helps digestion, sheet Invention can be effectively used for the treatment of children's sitophobia disease, curative effect affirmative, and by clinic application, achieve good curative effect, relevant examination Certification of registered capital material is as follows:
1 data and method
The standard of 1.1 selection cases:Selector closes the zinc-deficiency sitophobia disease infant 281 of inclusion criteria, wherein young girl 148 Example, boy 133,1~13 years old age, average age 2.9 years old.
1.2 diagnostic criteria:Children's sitophobia disease Western medicine diagnostic criteria:According to Zhu Futang《Practical paidonosology》Poor appetite > is just Normal 1/2, continue more than 2 weeks, with abdominal distension or stomachache, Nausea and vomiting, halitosis, defecate dilute or constipated, it is sour smelly, exclude organic Disease, spirit, drug factors.Children's sitophobia disease Chinese medical disease diagnostic criteria:Long-term poor appetite and without other diseases person;Complexion Few China, body is partially thin, but spiritual fair, no abdominal distention;There is improper feeding history, such as feed not timing is quantified, eating cold and uncooked food excessively, sweetness Savoury, snacks partial eclipse etc.;Laboratory examination blood zinc value is substantially less than normal value and (adopts fasting blood 2ml, normal value is 9.8~16.80 μmol/L);9.8 μm of ol/L of blood zinc < are zinc-deficiency standard.
1.3 therapeutic scheme
1.3.1 281 zinc deficiency in children sitophobia disease infants are randomly divided into combination of Chinese tradiational and Western medicine group 178, Western medicine group 103 by packet Example, two groups of indifferences on age, sex, disease degree, clinic has comparativity.
1.3.2 Western medicine group was using oral zinc gluconate .1~3 year old daily 50mg, 4~7 years old daily 100mg, 8~13 years old Daily 150mg, continuous application 20 days is 1 course for the treatment of.Combination of Chinese tradiational and Western medicine group:Western medicine group and Chinese medicine group therapeutic alliance of the present invention are taken, In addition to being taken by Western medicine group, while the oral present invention, 3 times a day, 1~3 years old each 20ml, 4~7 years old each 30ml, 8~13 years old Each 50ml, 15 days is 1 course for the treatment of.
2 therapeutic evaluatioies
2.1 criterion of therapeutical effect references《Chinese medical disease Standardization of diagnosis and curative effect》Main evaluation criteria is improved as with appetite to draft.Fully recover from an illness More:Appetite is significantly enhanced, and appetite is dramatically increased up to normal health children's level, and original symptom disappears substantially, every experimental index Return to normal.It is effective:Appetite takes a turn for the better, and appetite increase, original symptom turns for the better by and large, and every experimental index has improvement;Have Effect:Appetite takes a turn for the better, and appetite increase, original symptom mitigation, every experimental index slightly improves or changed less;It is invalid:Sitophobia master Disease and every experimental index are without improvement.
3 statistical procedures:Two groups of equal finished chemoradiotherapies of case for the treatment of results, halfway without exiting, without case lost to follow-up, treatment According to evaluation of clinical curative effect standard after end, to two groups of carry out therapeutic evaluatioies, specifically it see the table below.
Note:Through statistical analysis, two groups of total effective rates compare, there were significant differences the property of P < 0.05.
4 conclusions
Children's sitophobia disease belongs to the categories such as traditional Chinese medicine " disliking food ", " getting ill from overeating ", " dyspepsia ", " infantile malnutrition due to digestive disturbances or intestinalparasites ".It is due to pediatric diet Do not know to control " asthenic susceptibility of spleen ", often by breast food too or not as good as being hindered.Too refer to that breast food is forfeited one's integrity, famine is full immoderate.Overfeeding delicious food The unclean thing of thick greasy product, raw food, so that stopping in dyspepsia, accumulates into infantile malnutrition due to digestive disturbances or intestinalparasites, just so-called " product is the mother of infantile malnutrition due to digestive disturbances or intestinalparasites, and no product is not into infantile malnutrition due to digestive disturbances or intestinalparasites " in the course of time.This Invention thinks disease position in taste, rules for the treatment of invigorating the spleenization product, and promoting the circulation of qi helps digestion softening hard masses are led stagnant, and above infant there are no during taking medicine Any adverse reaction.And by observing two groups of cases, combination of Chinese tradiational and Western medicine group total effective rate 98.9%, hence it is evident that better than Western medicine Group total effective rate 79.61%, absolutely proving can promote the enteron aisle of zinc to inhale using therapy of combing traditional Chinese and Western medicine zinc deficiency in children sitophobia disease Receive, improve digestive function, improve body integral status, promote rehabilitation, the present invention is compared compared with similar drugs, and treatment cycle is bright Aobvious to shorten, cure rate is improved, effect stability, to the infant follow-up through present invention treatment and rehabilitation, there are no one repeatedly.
In summary, the present invention is the active drug for treating children's sitophobia disease, has actual clinical meaning, is on Chinese medicine One big creation, makes beneficial to society.

Claims (4)

1. a kind of Chinese medicine for treating sitophobia disease, it is characterised in that by by weight:Radix Codonopsis 8-10g, Chinese yam 11-13g, fructus amomi 5-7g, coix seed 11-13g, the membrane of a chicken's gizzard 11-13g, Fructus Aurantii 8-10g, bighead atractylodes rhizome 11-13g, Poria cocos 8-10g, dried orange peel 8-10g, stir-fry wheat Bud 11-13g, hawthorn 11-13g, Divine Comedy 11-13g, oyster 11-13g, pangolin 8-10g and tortoiseshell 8-10g make material medicine system Into, wherein, above-mentioned raw materials medicine is mixed, material medicine is added water to submerge, decocted, is first boiled with high heat, then with being cooked by slow fire 30-40 Minute, filtering obtains first time decoction liquor;The dregs of a decoction are added water to submerge, and are boiled by intense fire, then with being cooked by slow fire 20-30 minutes, are filtered, and obtain the Secondary decoction liquor, merges decoction liquor twice, produces.
2. the Chinese medicine for the treatment of sitophobia disease according to claim 1, it is characterised in that by following weight meter:Radix Codonopsis 8g, mountain Medicine 11g, fructus amomi 5g, coix seed 11g, the membrane of a chicken's gizzard 11g, Fructus Aurantii 8g, bighead atractylodes rhizome 11g, Poria cocos 8g, dried orange peel 8-10g, coloured malt 11g, mountain Short, bristly hair or beard 11g, Divine Comedy 11g, oyster 11g, pangolin 8g and tortoiseshell 8g are made as material medicine, wherein, above-mentioned raw materials medicine is mixed, Material medicine is added water to submerge, is decocted, is first boiled with high heat, then with being cooked by slow fire 30 minutes, filters, obtains first time decoction liquor;The dregs of a decoction Add water to submerge, boil by intense fire, then with being cooked by slow fire 20 minutes, filter, obtain second of decoction liquor, merge decoction liquor twice, produce.
3. the Chinese medicine for the treatment of sitophobia disease according to claim 1, it is characterised in that by following weight meter:Radix Codonopsis 9g, mountain Medicine 12g, fructus amomi 6g, coix seed 12g, the membrane of a chicken's gizzard 12g, Fructus Aurantii 9g, bighead atractylodes rhizome 12g, Poria cocos 9g, dried orange peel 9g, coloured malt 12g, hawthorn 12g, Divine Comedy 12g, oyster 12g, pangolin 9g and tortoiseshell 9g are made as material medicine, wherein, above-mentioned raw materials medicine is mixed, plus Water logging there is not material medicine, decocts, and first boils with high heat, then with being cooked by slow fire 35 minutes, filters, obtain first time decoction liquor;The dregs of a decoction add Water logging does not have, and boils by intense fire, then with being cooked by slow fire 25 minutes, filters, and obtains second of decoction liquor, merges decoction liquor twice, produce.
4. the Chinese medicine for the treatment of sitophobia disease according to claim 1, it is characterised in that by following weight meter:Radix Codonopsis 10g, Chinese yam 13g, fructus amomi 7g, coix seed 13g, the membrane of a chicken's gizzard 13g, Fructus Aurantii 10g, bighead atractylodes rhizome 13g, Poria cocos 10g, dried orange peel 10g, coloured malt 13g, Hawthorn 13g, Divine Comedy 13g, oyster 13g, pangolin 10g and tortoiseshell 10g are made as material medicine, wherein, by above-mentioned raw materials medicine Mixing, adds water to submerge material medicine, decocts, and first boils with high heat, then with being cooked by slow fire 40 minutes, filters, obtain first time decoction liquor; The dregs of a decoction are added water to submerge, and are boiled by intense fire, then with being cooked by slow fire 30 minutes, are filtered, and are obtained second of decoction liquor, are merged decoction liquor twice, i.e., .
CN201410750320.9A 2014-12-10 2014-12-10 A kind of Chinese medicine for treating sitophobia disease Expired - Fee Related CN104383423B (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102370931A (en) * 2011-11-25 2012-03-14 刘德忠 Medicament for stimulating appetite of children
CN103356989A (en) * 2013-07-24 2013-10-23 赵世明 Traditional Chinese medicine composition for treating incoordination between spleen and stomach

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102370931A (en) * 2011-11-25 2012-03-14 刘德忠 Medicament for stimulating appetite of children
CN103356989A (en) * 2013-07-24 2013-10-23 赵世明 Traditional Chinese medicine composition for treating incoordination between spleen and stomach

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
参苓白术散加减治疗小儿厌食症60例;曾秀池;《实用中医药杂志》;20080731;第24卷(第7期);第431页左栏第1,4-5段 *

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