CN104383395A - Traditional Chinese medicine composition for treating diabetic foot - Google Patents
Traditional Chinese medicine composition for treating diabetic foot Download PDFInfo
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/708—Rheum (rhubarb)
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
- A61K36/744—Gardenia
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/904—Stemonaceae (Stemona family), e.g. croomia
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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Abstract
The invention discloses a traditional Chinese medicine composition for treating a diabetic foot. The traditional Chinese medicine composition is prepared from the following components in parts by mass: 10-20 parts of rhubarb, 5-10 parts of tree peony bark, 10-20 parts of Chinese gall, 10-20 parts of prepared cape jasmine fruit, 5-10 parts of red peony root, 10-20 parts of golden cypress, 10-20 parts of light yellow sophora root, 10-20 parts of sessile stemona root and 10-20 parts of glabrous greenbrier rhizome; the rhubarb, the golden cypress and the prepared cape jasmine fruit are taken as monarch drugs and mainly used for clearing away heat and purging fire for removing toxin and leading the whole prescription; the light yellow sophora root and the sessile stemona root are taken as ministerial drugs and mainly used for clearing away heat and drying dampness; the red peony root is taken as an adjuvant drug to be matched with the rhubarb and mainly used for promoting blood circulation to remove blood stasis; the Chinese gall is taken as a conductant drug to be matched with the sessile stemona root and mainly used for astringing and promoting tissue regeneration; all the materials are combined together to achieve the effects of purging fire for removing toxin, dissipating stasis and promoting tissue regeneration; proven by clinical treatments, the effective rate of the traditional Chinese medicine composition for treating the diabetic foot is 100%, the cure rate is 51%, the effective rate is 38% and the improvement rate is 11%; and as a result, the traditional Chinese medicine composition has a good curative effect on the diabetic foot.
Description
Technical field
The present invention relates to the field of Chinese medicines, particularly a kind of Chinese medicine composition being used for the treatment of diabetic foot.
Background technology
Diabetic foot refers to because of diabetic angiopathy or the factor such as neuropathy and infection, causes a kind of pathological changes of diabetics foot or lower limb disorganization, often causes patients feet's sensory deprivation or attenuating and is subject to wound, so that amputation of having to.This disease is the severe diabetes mellitus complication threatening diabetics, to patient and family thereof.Society causes and has a strong impact on and bear.
Chinese medicine has greater advantage in treatment diabetic foot, and along with deepening continuously of research, the treatment of the traditional Chinese medical science to diabetic foot obtains very large progress.Because Chinese medicine has the advantage of the low and treating both the principal and secondary aspects of a disease of side effect, therefore become the preferred non-defective unit of diabetic foot.
Summary of the invention
The object of the present invention is to provide a kind of Chinese medicine composition for the treatment of diabetic foot.
In view of this, object of the present invention is achieved by the following technical programs, a kind of Chinese medicine composition for the treatment of diabetic foot, composed of the following components: according to the mass fraction, 10-20 part Radix Et Rhizoma Rhei, 5-10 part Cortex Moutan, 10-20 part Galla Chinensis, 10-20 part Fructus Gardeniae (parched), 5-10 part Radix Paeoniae Rubra, 10-20 part Cortex Phellodendri, 10-20 part Radix Sophorae Flavescentis, 10-20 part Radix Stemonae, 10-20 part Rhizoma Smilacis Glabrae, the source of described component is Chinese medicinal material or the Chinese medicine extract being equivalent to above-mentioned Chinese medicine crude drug amount.
The present invention also provides a kind of preparation method of above-mentioned Chinese medicine composition, comprises the following steps: by decocting after the mixing of the Chinese medicinal material of described component; By the mixture filter cleaner obtained after decocting, obtain Chinese medicine composition.
The present invention also provides a kind of Chinese medicine lotion prepared by above-mentioned Chinese medicine composition.
The present invention also provides a kind of preparation method of above-mentioned Chinese medicine lotion, comprise the following steps: by decocting after described Radix Et Rhizoma Rhei, Cortex Moutan, Galla Chinensis, Fructus Gardeniae (parched), Radix Paeoniae Rubra, Cortex Phellodendri, Radix Sophorae Flavescentis, the Radix Stemonae and Rhizoma Smilacis Glabrae mixing, after filter cleaner, then sterilizing, subpackage and sealing, obtain Chinese medicine lotion.
The present invention formulates in summary theory of Chinese medical science and clinical practice basis, is with Radix Et Rhizoma Rhei, Cortex Phellodendri, Fructus Gardeniae (parched) for monarch drug, main clearing away heat-fire removing toxic substances, the full side of commander; With Radix Sophorae Flavescentis, the Radix Stemonae for ministerial drug, main heat clearing and damp drying; Radix Paeoniae Rubra is adjuvant drug, joins Radix Et Rhizoma Rhei, main promoting blood circulation to remove blood stasis; Galla Chinensis, for making medicine, joins the Radix Stemonae, main convergence granulation promoting.All medicines are harmonious, and play the merit of eliminating fire and detoxication, dissipating blood stasis granulation promoting altogether.Diabetes foot of 0-grade, without open wound person, can put into about 40 DEG C of medicinal liquids and embathe by suffering limb with Chinese medicine lotion washout (1 bag/day) every day.There is open wound person, should wound be avoided, constantly dip in antiseptic gauze and spread in affected part soak while hot, note water temperature, avoid scalding, a course for the treatment of on the 15th.The present invention shows through clinical treatment, effective percentage 100%, recovery from illness 51%, effective 38%, takes a turn for the better 11%.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail.
The invention discloses a kind of Chinese medicine composition for the treatment of hyperglycemia, hyperlipidemia, composed of the following components: according to the mass fraction, 10-20 part Radix Et Rhizoma Rhei, 5-10 part Cortex Moutan, 10-20 part Galla Chinensis, 10-20 part Fructus Gardeniae (parched), 5-10 part Radix Paeoniae Rubra, 10-20 part Cortex Phellodendri, 10-20 part Radix Sophorae Flavescentis, 10-20 part Radix Stemonae, 10-20 part Rhizoma Smilacis Glabrae, the source of described component is Chinese medicinal material or the Chinese medicine extract being equivalent to above-mentioned Chinese medicine crude drug amount.
In above-mentioned Chinese medicine composition provided by the invention, Radix Et Rhizoma Rhei, Cortex Phellodendri, Fructus Gardeniae (parched) are monarch drug, main clearing away heat-fire removing toxic substances, the full side of commander; With Radix Sophorae Flavescentis, the Radix Stemonae for ministerial drug, main heat clearing and damp drying; Radix Paeoniae Rubra is adjuvant drug, joins Radix Et Rhizoma Rhei, main promoting blood circulation to remove blood stasis; Galla Chinensis, for making medicine, joins the Radix Stemonae, main convergence granulation promoting.All medicines are harmonious, and play the merit of eliminating fire and detoxication, dissipating blood stasis granulation promoting altogether.To diabetic foot, there is good curative effect.
Medicine has the speciality of individual character, and there is gregarious magical effect side, with Radix Et Rhizoma Rhei, Cortex Phellodendri, Fructus Gardeniae (parched) for monarch drug, and main clearing away heat-fire removing toxic substances, the full side of commander; With Radix Sophorae Flavescentis, the Radix Stemonae for ministerial drug, main heat clearing and damp drying; Radix Paeoniae Rubra is adjuvant drug, joins Radix Et Rhizoma Rhei, main promoting blood circulation to remove blood stasis; Galla Chinensis, for making medicine, joins the Radix Stemonae, main convergence granulation promoting.All medicines are harmonious, and play the merit of eliminating fire and detoxication, dissipating blood stasis granulation promoting altogether.
The present invention also provides a kind of preparation method of aforementioned pharmaceutical compositions, comprising: by decocting after the mixing of the Chinese medicinal material of described component; By the mixture filter cleaner obtained after decocting, obtain Chinese medicine composition.
The Chinese medicine lotion that the present invention also provides a kind of above-mentioned Chinese medicine composition to prepare.
The present invention also provides a kind of preparation method of above-mentioned Chinese medicine composition Chinese medicine lotion, comprise the following steps: by decocting after described Radix Et Rhizoma Rhei, Cortex Moutan, Galla Chinensis, Fructus Gardeniae (parched), Radix Paeoniae Rubra, Cortex Phellodendri, Radix Sophorae Flavescentis, the Radix Stemonae and Rhizoma Smilacis Glabrae mixing, after filter cleaner, sterilizing again, subpackage and sealing, obtain Chinese medicine lotion.
Embodiment one:
Radix Et Rhizoma Rhei 2Kg, Cortex Moutan 1 Kg, Galla Chinensis 2Kg, Fructus Gardeniae (parched) 2Kg, Radix Paeoniae Rubra 1 Kg, Cortex Phellodendri 2Kg, Radix Sophorae Flavescentis 2Kg, Radix Stemonae 2Kg, Rhizoma Smilacis Glabrae 2Kg, the source of described component is Chinese medicinal material or the Chinese medicine extract being equivalent to above-mentioned Chinese medicine crude drug amount, adds 30L decocting to 20L after mixing; By the mixture filter cleaner obtained after decocting, obtain Chinese medicine composition.
Embodiment two:
30L decocting is added to 20L by after Radix Et Rhizoma Rhei 2Kg, Cortex Moutan 1Kg, Galla Chinensis 2 Kg, Fructus Gardeniae (parched) 2 Kg, Radix Paeoniae Rubra 1Kg, Cortex Phellodendri 2 Kg, Radix Sophorae Flavescentis 2 Kg, the Radix Stemonae 2 Kg, Rhizoma Smilacis Glabrae 2 Kg mixing, after filter cleaner, sterilizing again, subpackage and sealing, obtain Chinese medicine lotion, make the Chinese medicine lotion of 200ml/ bag.
Embodiment three:
Radix Et Rhizoma Rhei 2Kg, Cortex Moutan 1.5 Kg, Galla Chinensis 2 Kg, Fructus Gardeniae (parched) 2 Kg, Radix Paeoniae Rubra 1.5 Kg, Cortex Phellodendri 2 Kg, Radix Sophorae Flavescentis 2 Kg, the Radix Stemonae 2 Kg, Rhizoma Smilacis Glabrae 2 Kg are added 30L decocting to 20L after mixing, after filter cleaner, sterilizing again, subpackage and sealing, obtain Chinese medicine lotion, make the Chinese medicine lotion of 200ml/ bag.
Embodiment four:
Radix Et Rhizoma Rhei 2Kg, Cortex Moutan 0.5 Kg, Galla Chinensis 2 Kg, Fructus Gardeniae (parched) 2 Kg, Radix Paeoniae Rubra 0.5 Kg, Cortex Phellodendri 2 Kg, Radix Sophorae Flavescentis 2 Kg, the Radix Stemonae 2 Kg, Rhizoma Smilacis Glabrae 2 Kg are added 30L decocting to 20L after mixing, after filter cleaner, sterilizing again, subpackage and sealing, obtain Chinese medicine lotion, make the Chinese medicine lotion of 200ml/ bag.
Embodiment five:
Radix Et Rhizoma Rhei 1Kg, Cortex Moutan 1Kg, Galla Chinensis 1 Kg, Fructus Gardeniae (parched) 1 Kg, Radix Paeoniae Rubra 1Kg, Cortex Phellodendri 1Kg, Radix Sophorae Flavescentis 1 Kg, Radix Stemonae 1Kg, Rhizoma Smilacis Glabrae 1 Kg are added 30L decocting to 20L after mixing, after filter cleaner, sterilizing again, subpackage and sealing, obtain Chinese medicine lotion, make the Chinese medicine lotion of 200ml/ bag.
The clinical efficacy of Chinese medicine composition provided by the invention is added up, chooses 100 patient with diabetic feet cases.Wherein male 61 example, women 39 example, 20 years old age-40 years old 10 example 41 years old-60 years old is 55 examples, within more than 61 years old, is 35 examples.Diabetes foot of 0-grade, without open wound person, can put into about 40 DEG C of medicinal liquids and invade and wash by suffering limb with Chinese medicine lotion washout (1 bag/day) every day.There is open wound person, should wound be avoided, constantly dip in antiseptic gauze and spread in affected part soak while hot, note water temperature, avoid scalding, a course for the treatment of on the 15th.Check curative effect after 15 days, curative effect statistical result sees the following form.
Recovery from illness refers to that ulcer surface heals completely, has formed crust or cicatrix; Effectively refer to that decline 2 grades or ulcer surface of classification reduces >50%; Improvement refers to that decline 1 grade or ulcer surface of classification reduces <50%; Invalidly refer to that wound surface is without obvious reduction, local is without significant change, or sb.'s illness took a turn for the worse.
The clinical efficacy statistical result of Chinese medicine lotion provided by the invention
| Add up to (example) | Recovery from illness (example) | Effective (example) | Take a turn for the better (example) | Invalid (example) |
| 100 | 51 | 38 | 11 | 0 |
Liu, female, 62 years old, in more than 10 years of diabetes mellitus's medical history, subcutaneous insulin controlled blood glucose usually, and glycemic control still can.Medical disease sees left heel portion ulceration, and diameter is about 6cm, and pain is obvious, and Pi Wen increases, xerostomia, weak, receive can, frequent micturition, stool still can.Give Chinese medicine lotion, every day 1 bag of washout, after January ulceration place incrustation, without obvious pain.
Lee, female, 71 years old, in more than 15 years of diabetes mellitus's medical history, subcutaneous insulin controlled blood glucose usually, and glycemic control still can.Medical disease sees the swelling of right foot swelling fourth, fifth toe, necrosis is festered, the black pus of Huang that wound secretion is stench, obvious pain.Give Chinese medicine lotion, every day 1 bag of washout, after 7 days, symptom is clearly better, after January ulceration place incrustation.
Wang, man, 57 years old, in more than 5 years of diabetes mellitus's medical history, subcutaneous insulin controlled blood glucose usually, and glycemic control still can.The left sufficient ulceration of medical disease meeting, ooze out a small amount of ichor sexual secretion, pain is obvious.Give Chinese medicine lotion, every day 1 bag of washout, after 7 days, topical ulcers reduction of area is little by 30%, after 15 days ulceration place incrustation.
The above is only preferred embodiment of the present invention, not does any pro forma restriction to the present invention; Any those of ordinary skill in the art, do not departing under technical solution of the present invention ambit, the Method and Technology content of above-mentioned announcement all can be utilized to make many possible variations and modification to technical solution of the present invention, or be revised as the Equivalent embodiments of equivalent variations.Therefore, every content not departing from technical solution of the present invention, according to technical spirit of the present invention to any simple modification made for any of the above embodiments, equivalent replacement, equivalence change and modification, all still belongs in the scope of technical solution of the present invention protection.
Claims (4)
1. treat the Chinese medicine composition of diabetic foot for one kind, it is characterized in that, composed of the following components: according to the mass fraction, 10-20 part Radix Et Rhizoma Rhei, 5-10 part Cortex Moutan, 10-20 part Galla Chinensis, 10-20 part Fructus Gardeniae (parched), 5-10 part Radix Paeoniae Rubra, 10-20 part Cortex Phellodendri, 10-20 part Radix Sophorae Flavescentis, 10-20 part Radix Stemonae, 10-20 part Rhizoma Smilacis Glabrae, the source of described component is Chinese medicinal material or the Chinese medicine extract being equivalent to above-mentioned Chinese medicine crude drug amount.
2. the preparation method of Chinese medicine composition according to claim 1, is characterized in that, comprises the following steps: by decocting after described Radix Et Rhizoma Rhei, Cortex Moutan, Galla Chinensis, Fructus Gardeniae (parched), Radix Paeoniae Rubra, Cortex Phellodendri, Radix Sophorae Flavescentis, the Radix Stemonae and Rhizoma Smilacis Glabrae mixing; By the mixture filter cleaner obtained after decocting, obtain Chinese medicine composition.
3. the Chinese medicine lotion prepared by Chinese medicine composition described in claim 1.
4. the preparation method of Chinese medicine lotion according to claim 3, it is characterized in that, comprise the following steps: by decocting after described Radix Et Rhizoma Rhei, Cortex Moutan, Galla Chinensis, Fructus Gardeniae (parched), Radix Paeoniae Rubra, Cortex Phellodendri, Radix Sophorae Flavescentis, the Radix Stemonae and Rhizoma Smilacis Glabrae mixing, after filter cleaner, sterilizing again, subpackage and sealing, obtain Chinese medicine lotion.
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| CN201410656253.4A CN104383395A (en) | 2014-11-18 | 2014-11-18 | Traditional Chinese medicine composition for treating diabetic foot |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN107551054A (en) * | 2017-10-31 | 2018-01-09 | 广东省中医院 | Sugared numbness washout side composition, its preparation method and its application |
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| 方晴: "糖尿病足的病因病机与外治近况", 《中医外治杂志》 * |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107551054A (en) * | 2017-10-31 | 2018-01-09 | 广东省中医院 | Sugared numbness washout side composition, its preparation method and its application |
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