CN104383353B - A kind of preparation method of medicine ink - Google Patents

A kind of preparation method of medicine ink Download PDF

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Publication number
CN104383353B
CN104383353B CN201410800967.8A CN201410800967A CN104383353B CN 104383353 B CN104383353 B CN 104383353B CN 201410800967 A CN201410800967 A CN 201410800967A CN 104383353 B CN104383353 B CN 104383353B
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medicinal material
gelatin
extraction
tung oil
cornus bubali
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CN104383353A (en
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张礼春
胡中
胡一中
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ANHUI MOYAO PHARMACEUTICAL Co Ltd
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ANHUI MOYAO PHARMACEUTICAL Co Ltd
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/32Bones; Osteocytes; Osteoblasts; Tendons; Tenocytes; Teeth; Odontoblasts; Cartilage; Chondrocytes; Synovial membrane
    • AHUMAN NECESSITIES
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    • A61K35/56Materials from animals other than mammals
    • A61K35/60Fish, e.g. seahorses; Fish eggs
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K35/56Materials from animals other than mammals
    • A61K35/65Amphibians, e.g. toads, frogs, salamanders or newts
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236Ligusticum (licorice-root)
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
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    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
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    • A61K36/62Nymphaeaceae (Water-lily family)
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    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
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    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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Abstract

The present invention discloses a kind of preparation method of medicine ink, it is medicinal material that this method, which chooses 20 kinds of traditional Chinese medicines such as PULVIS CORNUS BUBALI CONCEN TRATUS, antelope's horn, Moschus, borneol, pearl, the dried venom of toads, it is made by the process such as the extraction of medicinal material, ultra-fine grinding, stirring mixing, sterilizing, drying, compressing, present invention process is fine, the medicinal material of making is evident in efficacy for various skin oral cavity and throat persistent ailments, such as ichthyosis, chronic eczema, chronic urticaria, herpes zoster, neurodermatitis, stubborn dermatitis, acne, acne rosacea nameless sores or boils, chronic pharyngitis, recurrence canker sore.

Description

A kind of preparation method of medicine ink
Technical field
Make field the present invention relates to Chinese medicine, more particularly to it is a kind of treat chronic eczema, the medicine ink of the persistent ailment such as chronic pharyngitis Preparation method.
Background technology
For various skin oral cavity and throat persistent ailment such as ichthyosis, chronic eczema, chronic urticaria, herpes zoster, nerves Dermatitis, stubborn dermatitis, acne, acne rosacea nameless sores or boils, chronic pharyngitis, recurrence canker sore these persistent ailments perplex many patients always, Its healing process is numerous and diverse, high cost, and never a kind of effectively simple medicine can replace, it is a kind of with bear gall, antelope's horn, The courage of the eight treasures (choice ingredients of certain special dishes) such as pearl five is that the medicine ink that main components matching gelatin and prepared Chinese ink are fabricated to is produced therewith.
The content of the invention
It is an object of the invention to provide a kind of eliminating inflammation and expelling toxin, promoting blood circulation and stopping pain, for having blood in stool, under dysentery, ulcer sores, Nameless sores or boils, the black preparation method of medicine of the disease such as stubborn dermatitis, dermatitis, eczema.
The present invention can be achieved through the following technical solutions:
A kind of preparation method of medicine ink, this method specifically includes following steps:
1)Medicinal material is chosen:Choose PULVIS CORNUS BUBALI CONCEN TRATUS 15g, antelope's horn 30g, Moschus 100g, borneol 100g, pearl 120g, Dried venom of toads 15g, cow-bezoar 15g, cinnabar 24g, 5, ox courage, bear gall 10g, snake gall 10, pig gall 15, rhizome of chuanxiong 100g, swertia mileensis 10 Individual, rhizoma nelumbinis 150g, safflower 70g, field thistle 150g, setose thistle 150g, rhizoma imperatae 400g, selfheal 200g, moutan bark 100g, fourth Fragrant 70g, gelatin 20g, water chestnut starch 200g, tung oil cigarette 200g;
2)The extraction of medicinal material:Unit is concentrated using traditional Chinese medicine extraction, except PULVIS CORNUS BUBALI CONCEN TRATUS, gelatin, water chestnut starch, tung oil cigarette etc. Outside, Ligusticum wallichii, safflower, rhizoma nelumbinis, setose thistle, selfheal, cogongrass grass, cloves, moutan bark is taken to add water, first normal temperature ultrasonic wave extraction, so Temperature control carries out pressurized treatments at 100 DEG C afterwards, and finally decompression is -800Mpt, and temperature control concentrates out concoction at 75 DEG C, is decocted Boil three times, every time 3 hours;
3)Ultra-fine grinding:Practical superfine pulverizer carries out ultra-fine grinding, and sieving adds PULVIS CORNUS BUBALI CONCEN TRATUS and Ligusticum wallichii etc. nine The concentrate of taste is mixed so that supplementary material granularity reaches nanoscale;
4)Stirring mixing:Concoction after crushing is stirred into mixing, gelatin 20g is separately taken, adds water and water chestnut starch is added after evaporating 200g, is well mixed using high-speed mixing equipment;
5)Sterilizing, drying:Medicinal material is dried using automatic sterilizing thermostatic control device, temperature control is added at 75-80 DEG C Tung oil cigarette 200g, it is to avoid the volatilization containing fragrant ingredient is lost in prescription;
6)It is compressing:Use operating pressure compressing, last outer packing for the ingot pressing machine of 150,000 newton.
Beneficial effects of the present invention:The present invention is not cured skin oral cavity and throat persistent ailment, such as ichthyosis, chronic for many years for various Eczema, chronic urticaria, herpes zoster, neurodermatitis, stubborn dermatitis, acne, acne rosacea nameless sores or boils, chronic pharyngitis, recurrence mouth The clinical effective rates such as chamber ulcer are up to 99%, and cure rate is that recurrence rate is only 3% in 89%, 3 years, except few patients need Long-term taking medicine Outside relief of symptoms, Most patients are in the 2-4 courses for the treatment of(The 1-2 months)Thoroughly cure.
Embodiment
The present invention is described in further detail with reference to specific embodiment.
Embodiment 1
1)Take following medicinal material:PULVIS CORNUS BUBALI CONCEN TRATUS 15g, antelope's horn 30g, Moschus 100g, borneol 100g, pearl 120g, toad Crisp 15g, cow-bezoar 15g, cinnabar 24g, 5, ox courage, bear gall 10g, snake gall 10, pig gall 15, rhizome of chuanxiong 100g, swertia mileensis 10, Rhizoma nelumbinis 150g, safflower 70g, field thistle 150g, setose thistle 150g, rhizoma imperatae 400g, selfheal 200g, moutan bark 100g, cloves 70g, gelatin 20g, water chestnut starch 200g, tung oil cigarette 200g.
2)The extraction of medicinal material:Unit is concentrated using traditional Chinese medicine extraction, except PULVIS CORNUS BUBALI CONCEN TRATUS, gelatin, water chestnut starch, tung oil cigarette etc. Outside, Ligusticum wallichii, safflower, rhizoma nelumbinis, setose thistle, selfheal, cogongrass grass, cloves, moutan bark is taken to add water, first normal temperature ultrasonic wave extraction, so Temperature control carries out pressurized treatments at 100 DEG C afterwards, and finally decompression is -800Mpt, and temperature control concentrates out concoction at 75 DEG C, is decocted Boil three times, every time 3 hours;
3)Ultra-fine grinding:Practical superfine pulverizer carries out ultra-fine grinding, and sieving adds PULVIS CORNUS BUBALI CONCEN TRATUS and Ligusticum wallichii etc. nine The concentrate of taste is mixed so that supplementary material granularity reaches nanoscale;
4)Stirring mixing:Concoction after crushing is stirred into mixing, gelatin 20g is separately taken, adds water and water chestnut starch is added after evaporating 200g, is well mixed using high-speed mixing equipment;
5)Sterilizing, drying:Medicinal material is dried using automatic sterilizing thermostatic control device, temperature control is added at 75-80 DEG C Tung oil cigarette 200g, it is to avoid the volatilization containing fragrant ingredient is lost in prescription;
6)It is compressing:Use operating pressure compressing, last outer packing for the ingot pressing machine of 150,000 newton.
Clinical test 1:
Lin, man, 40 years old, Suburbs of Hefei peasant, medical history summary:On 2 10th, 2010 to treat when, two legs are all There is 200mm small papule, scratched by hand, there is liquid to ooze out, clearly write in the diagnosis records sheet of other hospital diagnosis and be Eczema, patient's readme suffers from eczema 15 years, sees the doctor for treatment everywhere, never cures, and all breaks out every year several times.Through going through, category Subacute eczema, starts to take medicine of the present invention, takes 3 days, affected part is clearly better, and affected part is not in itch;Take 15 days, affected part Incrustation, the skin exfoliation of lesion;It is continuous to take a thoroughly healing in month;Follow-up, does not recur so far.
Clinical trial 2:
Huang, female, 19 years old, middle school student.Medical history is made a summary, and the pale red tubercle thing of soya bean size is suffered from groin, really Examine as scabies tubercle, with violent itch, add water to smash to pieces using the medicine ink of the present invention is applied to affected part, medicine thickness degree 1 for paste Millimeter, daily 2 times, one week be a course for the treatment of, and two courses for the treatment of are cured.
Above-mentioned specific embodiment is only the specific case of the present invention, and scope of patent protection of the invention includes but is not limited to State specific embodiment, it is any to meet claims of the present invention and any person of an ordinary skill in the technical field is done to it Appropriate change or modification, should all fall into the present invention scope of patent protection.

Claims (1)

1. a kind of preparation method of medicine ink, it is characterised in that this method specifically includes following steps:
1)Medicinal material is chosen:Choose PULVIS CORNUS BUBALI CONCEN TRATUS 15g, antelope's horn 30g, Moschus 100g, borneol 100g, pearl 120g, the dried venom of toads 15g, cow-bezoar 15g, cinnabar 24g, 5, ox courage, bear gall 10g, snake gall 10, pig gall 15, rhizome of chuanxiong 100g, swertia mileensis 10, lotus root Save 150g, safflower 70g, field thistle 150g, setose thistle 150g, rhizoma imperatae 400g, selfheal 200g, moutan bark 100g, cloves 70g, Gelatin 20g, water chestnut starch 200g, tung oil cigarette 200g;
2)The extraction of medicinal material:Unit is concentrated using traditional Chinese medicine extraction, in addition to PULVIS CORNUS BUBALI CONCEN TRATUS, gelatin, water chestnut starch, tung oil cigarette etc., Ligusticum wallichii, safflower, rhizoma nelumbinis, setose thistle, selfheal, cogongrass grass, cloves, moutan bark is taken to add water, first normal temperature ultrasonic wave extraction, Ran Houwen Degree control carries out pressurized treatments at 100 DEG C, and finally decompression is -800Mpt, and temperature control concentrates out concoction at 75 DEG C, decocts three It is secondary, 3 hours every time;
3)Ultra-fine grinding:Practical superfine pulverizer carries out ultra-fine grinding, and sieving adds the taste of PULVIS CORNUS BUBALI CONCEN TRATUS and Ligusticum wallichii etc. nine Concentrate is mixed so that supplementary material granularity reaches nanoscale;
4)Stirring mixing:Concoction after crushing is stirred into mixing, gelatin 20g is separately taken, adds water and water chestnut starch 200g is added after evaporating, adopt It is well mixed with high-speed mixing equipment;
5)Sterilizing, drying:Medicinal material is dried using automatic sterilizing thermostatic control device, temperature control adds tung oil at 75-80 DEG C Cigarette 200g, it is to avoid the volatilization containing fragrant ingredient is lost in prescription;
6)It is compressing:Use operating pressure compressing, last outer packing for the ingot pressing machine of 150,000 newton.
CN201410800967.8A 2014-12-22 2014-12-22 A kind of preparation method of medicine ink Active CN104383353B (en)

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