CN104383053A - Traditional Chinese medicine preparation for treating urinary tract infection and production method of traditional Chinese medicine preparation - Google Patents

Traditional Chinese medicine preparation for treating urinary tract infection and production method of traditional Chinese medicine preparation Download PDF

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CN104383053A
CN104383053A CN201410719206.XA CN201410719206A CN104383053A CN 104383053 A CN104383053 A CN 104383053A CN 201410719206 A CN201410719206 A CN 201410719206A CN 104383053 A CN104383053 A CN 104383053A
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herba
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CN104383053B (en
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江志强
卢玲玲
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/57Magnoliaceae (Magnolia family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/233Bupleurum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/79Schisandraceae (Schisandra family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/10Preparation or pretreatment of starting material
    • A61K2236/15Preparation or pretreatment of starting material involving mechanical treatment, e.g. chopping up, cutting or grinding
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

Abstract

The invention discloses a traditional Chinese medicine preparation for treating urinary tract infection and a production method of the traditional Chinese medicine preparation, and belongs to the field of traditional Chinese medicine. The active ingredients of the traditional Chinese medicine preparation are obtained from such raw materials as flower of bailan, herb of sword brake, medicinal fatheadtree, Chinese brake herb, ciliatenerve knotweed root, tuberous sword fern, japan clover herb, lotus stamen, Chinese magnoliavine fruit, gordon enryale seed, all-grass of dwarf clearweed, kirilow groundsel herb, twelve stamen melastoma herb, herb of common rue, radix bupleuri and greater celandine herb; the traditional Chinese medicine preparation is appropriate in material selection and compatibility, conforms to the traditional Chinese medicine theory and the modern medicine theory, and has the effects of clearing away heat and toxic materials, excreting dampness and inducing diuresis, diminishing inflammation and relieving pain, and supplementing qi and promoting the production of body fluid; besides, the traditional Chinese medicine preparation is convenient to use, good in absorption effect, and free from adverse and toxic and side effects; as being clinically verified, the traditional Chinese medicine preparation is capable of harmonizing the exterior and interior, dispelling wind-evil and bringing down a fever, inducing diuresis and activating blood, and improving the internal and external environments of the organism, thereby treating or attenuating various symptoms of the urinary tract infection, and is suitable for popularization and application to the clinical treatment and nursing of the urinary tract infection.

Description

A kind of Chinese medicine preparation and preparation method for the treatment of urinary tract infection
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of Chinese medicine preparation and preparation method for the treatment of urinary tract infection.
Background technology
Urinary tract infection, also known as urinary system infection, is that urothelium invades the inflammatory reaction caused to antibacterial, is usually attended by bacteriuria and pyuria.Urinary tract infection is divided into upper urinary tract infection and lower urinary tract infection according to infection site; Can be divided into isolated or sporadic infection and recurrent infection according to the relation between two subinfections, the latter can be divided into again and infecting and antibacterial sustainable existence again, and antibacterial sustainable existence is also referred to as recurrence; Pure urinary tract infection, complexity urinary tract infection and urine pyemia can be divided into again according to urinary tract state when infecting outbreak.Urinary tract infection is often mainly in women, is especially mainly in sexual life active phase and postmenopausal women.
The clinical manifestation of urinary tract infection has:
1. acute simplex cystitis, suddenly, female patient morbidity is how relevant with sexual activity in morbidity.Main manifestations is that bladder irritation is levied, i.e. frequent micturition, urgent micturition, dysurea, the uncomfortable and urethra burn feeling of bladder area or perineal position; Frequent micturition degree varies, can urge incontinence be there is in severe patient; There is leukocyte, common terminal hematuria in urine muddiness, urine, be total hematuria sometimes, even see that clot is discharged.General without obvious systemic infection symptom, body temperature is normal or have low grade fever.
2. acute simplex pyelonephritis: (1) urinary system symptom.Comprise the bladder irritations such as frequent micturition, urgent micturition, dysurea to levy, hematuria, Ipsilateral or bilateral lumbago, Ipsilateral costovertebral angle has obvious tenderness or percussion pain etc.;
(2) symptom of systemic infection.As shiver with cold, high heat, headache, Nausea and vomiting, inappetence etc., often speed with Leukocyte Counts rising and erythrocyte sedimentation rate.
3. asymptomatic bacteriuria, asymptomatic bacteriuria is a kind of invisible urinary tract infection, is more common in old women and pregnancy women, and patient is without any urinary tract infection symptom, and sickness rate increases with the age and increases.
4. complexity urinary tract infection, the clinical manifestation of complexity urinary tract infection is widely different, often with the other diseases having increased access to infection or Endodontic failure risk, can accompany or without clinical symptoms (as frequent micturition, urgent micturition, dysurea, dysuria, low-back pain, costovertebral angle tenderness, suprapubic region pain and heating etc.).Complexity urinary tract infection is normal with other diseases, as diabetes and renal failure.
Urinary tract infection very harmful, its sequela caused is also more, and the most serious and the most fatal situation comprises urine pyemia and renal failure, and renal failure can be divided into acute and chronic, and reversible and irreversible etc., harm should not be underestimated.The medicine of current treatment urinary tract infection has a lot, such as antibiotic, ofloxacin, ofloxacin etc., this kind of poisonous side effect of medicine is strong, long-term effect is not good, and it is expensive, have a strong impact on the intestines and stomach etc. of patient, so to the necessary safety of the medicine for the treatment of urinary tract infection, effectively, have no side effect, and Chinese materia medica is as the traditional medicine of China, there is effect strong, instant effect, the advantages such as lasting medicine, and there is no dependency, drug resistance and toxic and side effects, therefore a kind of Chinese medicine preparation is selected to treat urinary tract infection, to there is very important clinical meaning for urinary tract infection.
Summary of the invention
The invention provides a kind of Chinese medicine preparation and preparation method for the treatment of urinary tract infection; Chinese medicine preparation of the present invention selected medical material compatibility is suitable, meet Chinese medicine and modern medicine theory, there is effect of heat-clearing and toxic substances removing, eliminating dampness by diuresis diuresis, anti-inflammatory analgetic, supplementing QI for promoting the production of body fluid, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, can reconciling superficies and interior, dispel the wind bring down a fever, diuresis invigorates blood circulation, and improves body internal and external environment, thus treatment or alleviate the various symptoms of urinary tract infection, be suitable for urinary tract infection clinical treatment and nursing is applied.
For achieving the above object, technical scheme of the present invention is implemented as follows:
Treat a Chinese medicine preparation for urinary tract infection, raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Treat a preparation method for the Chinese medicine preparation of urinary tract infection, comprise following processing step:
(1) Flos micheliae Albae, Herba Pteridis Multifidae, Semen Euryales, Herba Senecionis Kirilowi and Herba rutae are removed impurity, clean, surface uniform sprays vinegar liquid, vexed, and put interior the slow fire of pot and add and propagandize hotly to tack-free, microwave drying, is placed in mortar and grinds into powder, mistake 120 order fine powders, for subsequent use;
(2) by CUIYUNCAO, Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae), Stamen Nelumbinis, tongue spray and Herba Chelidonii decontamination, clean, microwave drying, is placed in mortar and grinds into powder, crosses 140 order fine powders, for subsequent use;
(3) Lignum et Radix Naucleae, Radix Polygoni Ciliinerve, Herba Kummerowiae Striatae, Herba Melastomatis Dodecandri and Radix Bupleuri decontamination are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, under simmer down to 60 DEG C of environment, relative density is the thick paste of 1.12 ~ 1.15, for subsequent use;
(4) Fructus Schisandrae Chinensis is cleaned, add a small amount of vinegar liquid, silently, put in pot and steam, until blackening, take out, dry, be placed in mortar and smash to pieces, get fine powder, cross 170 order fine powders, for subsequent use;
(5) fine powder obtained by above-mentioned steps (1), step (2), step (4) and the thick paste obtained by step (3) are stirred, make tablet, be the Chinese medicine preparation of described treatment urinary tract infection.
The property of medicine of the present invention's Chinese medicine used is as follows:
Flos micheliae Albae: bitter in the mouth, pungent, slightly warm in nature.Removing dampness by means of aromatics, diuresis, relieving cough and resolving phlegm.For urinary system infection, dysuria, bronchitis, pertussis, uncomfortable in chest, thirsty, prostatitis, leucorrhea." conventional Chinese herbal medicine handbook " carries: " activating QI and resolving turbid pathogen, cough-relieving.Control prostatitis, women leucorrhea, infantile bronchitis, asthenia chronic cough.”
CUIYUNCAO: sweet in the mouth, light, cool in nature; GUIXIN warp.Clearing away heat-damp and promoting diuresis, hemostasis cough-relieving.For acute icteric infectious hepatitis, cholecystitis, enteritis and dysentery, oedema due to nephritis, urinary system infection, rheumatic arthritis, hemoptysis of pulmonary tuberculosis, traumatic hemorrhage, traumatic injury.
Lignum et Radix Naucleae: bitter in the mouth, cold in nature; Return lung, large intestine, gallbladder, urinary bladder channel.Heat-clearing and toxic substances removing, reducing swelling and alleviating pain.For cold, fever, acute tonsillitis, pharyngolaryngitis, bronchitis, pneumonia, urinary system infection, cholecystitis." conventional Chinese herbal medicine handbook " carries: " heat-clearing and toxic substances removing, reducing swelling and alleviating pain.Treating acute tonsillitis, pharyngolaryngitis, mastitis, enteritis, bacillary dysentery, urinary tract infection, cholecystitis, ulcer of the lower limb, tinea pedis infects, furuncle and phyma pus infections, dermatitis and eczema.”
Herba Pteridis Multifidae: lightly seasoned, micro-hardship, cool in nature; Return kidney, stomach warp.Clearing away heat-damp and promoting diuresis, removing toxic substances dysentery relieving, cooling blood for hemostasis.For dysentery, gastroenteritis, hepatitis, urinary system infection, cat fever, laryngopharynx swelling and pain, leucorrhea, metrorrhagia, pesticide intoxication." Guizhou side among the people medicine collection " carries: " antipyretic, diuresis.Control infantile convulsion, night cries.”
Radix Polygoni Ciliinerve: sour in the mouth, hardship, puckery, cool in nature; Return lung, large intestine, Liver Channel.Heat-clearing and toxic substances removing, removing heat from blood and promoting blood circulation.For respiratory tract infection, tonsillitis, acute bacillary dysentery, acute enteritis, urinary system infection, multiple hemorrhage, traumatic injury, menoxenia." Japan hanako materia medica " carries: " tonify deficiency labor, helps waist knee joint, beneficial color for strengthening bone and muscle, aid yang qi.”
Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae): sweet in the mouth, light, micro-puckery, cool in nature; Return liver, kidney, stomach, small intestine meridian.Clearing away heat-damp and promoting diuresis, peaceful lung cough-relieving, softening the hard mass removing food stagnancy.For cold, fever, cough, hemoptysis of pulmonary tuberculosis, dysentery, acute enteritis, infantile malnutrition, toxic indigestion, urinary system infection; Mastitis are controlled in external, lymphadenitis." Quanzhou book on Chinese herbal medicine " carries: " heat-clearing and toxic substances removing, diuresis.Control jaundice due to damp-heat, dysuria, regurgitation is dysphagic, hernia.”
Herba Kummerowiae Striatae: sweet in the mouth, light, cold nature; Return liver, spleen, lung, kidney channel.Heat-clearing and toxic substances removing, activating blood and eliminatng dampness, antidiarrheal.For gastroenteritis, dysentery, hepatitis, nyctalopia, urinary system infection, traumatic injury, furuncle furuncle and phyma." Chinese herbal medicine is commonly used in Shanghai " carries: " cure cold heating, cough chest pain, urinary tract infection, enteritis, dysentery.”
Stamen Nelumbinis: sweet in the mouth, puckery, property is put down; GUIXIN, kidney channel.Clear away heart-fire kidney tonifying, unsmoothing the sperm and stopping bleeding.For seminal emission, frequent micturition, the enuresis, leukorrhagia, spits blood, metrorrhagia." detailed outline " carries: " clear away heart-fire logical kidney, controlling nocturnal emission with astringent drugs gas, black beard and hair, improving healthy complexion, beneficial blood, and hemostasis is collapsed, spitted blood.”
Fructus Schisandrae Chinensis: sour in the mouth, sweet, warm in nature; Return lung, the heart, kidney channel.Restrain astringent or styptic treatment for spontaneous sweating, supplementing QI for promoting the production of body fluid, kidney calming.For chronic cough dyspnea due to deficiency, emission, enuresis frequent micturition, incessant chronic diarrhea, spontaneous perspiration, night sweat, Tianjin wound is thirsty, and deficient pulse of losing heart, interior-heat is quenched one's thirst, palpitation and insomnia." herbal classic " carries: " main QI invigorating, cough with dyspnea, the thin degree of impairment caused by overstrain, tonifying for the deficiency, reinforcing YIN-essence, beneficial man's essence.”
Semen Euryales: sweet in the mouth, puckery, property is put down; Return spleen, kidney channel.Supplementing the kidney to control the nocturnal, spleen reinforcing antidiarrheal, damp eliminating leukorrhagia stopping.For emission, enuresis frequent micturition, insufficiency of the spleen chronic diarrhea, nebulousurine, leukorrhagia." detailed outline " carries: " quench the thirst kidney tonifying.Control incontinence of urine, seminal emission, nebulousurine, leukorrhagia.”
Tongue spray: sweet in the mouth, cool in nature.Heat-clearing and toxic substances removing, eliminating dampness by diuresis diuresis.For tonsillitis, urinary tract infection, cervicitis, leucorrhea with red and white discharge.
Herba Senecionis Kirilowi: bitter in the mouth, micro-sweet, cold in nature; GUIXIN warp.Heat clearing away, removing toxic substances, diuresis.For lung abscess, urinary tract infection, dysuria, leukemia, stomatitis, furuncle and phyma." Zhejiang conventional medical herbs among the people " carries: " removing toxic substances, diuretic, promoting blood circulation and detumescence.”
Herba Melastomatis Dodecandri: sweet in the mouth, puckery, property is put down; Return liver,kidney,spleen, lung meridian.Heat-clearing and toxic substances removing, expelling wind and removing dampness, tonifying blood and arresting bleeding.For preventing the lonely inflammation of epidemic cerebrospinal, enteritis and dysentery, pelvic inflammatory disease, metrorrhagia, anemia leucorrhea, lumbago and skelalgia, rheumatic ostalgia, traumatic hemorrhage, venom." the south of Fujian Province traditional herbal medicine " carries: " heat-clearing and toxic substances removing, the hernia that disappears of invigorating blood circulation.Control dysentery with red and white feces, puerperal abdonimal pain.”
Herba rutae: acrid in the mouth, hardship, cold in nature.Dispel the wind and bring down a fever, diuresis is invigorated blood circulation, removing toxic substances and promoting subsidence of swelling.For cold, fever, rheumatic ostalgia, infantile convulsion, dysuria, hernia of having loose bowels, women's amenorrhea, traumatic injury, pathopyretic ulcer." Nanning City's medicine will " carries: " bring down a fever and dispel the wind, inducing diuresis to remove edema.Control fever of children infantile convulsion, rheumatic ostalgia.”
Radix Bupleuri: bitter in the mouth, is slightly cold, warm in nature; Return liver, gallbladder meridian.Reconciling superficies and interior, soothing the liver yang invigorating.For alternate attack of chill and fever, fullness in the chest and hypochondriac pain, bitter taste is deaf, headache and dizziness, malaria, lower sharp proctoptosis, menoxenia, uterine prolapse." not Lu " carries: " except dysphoria with smothery sensation under the typhoid fever heart, all expectorant accumulation of heats are real, evil inverse in the heart, five hide between faint breath, large intestine stops amassing, watery distension, and arthralgia chiefly caused by damp pathogen contracture.Also can do to bathe soup.”
Herba Chelidonii: bitter in the mouth, cool in nature, poisonous; GUIXIN, lung, spleen, stomach warp.Heat-clearing and toxic substances removing, pain relieving cough-relieving.For gastritis, gastric ulcer, stomachache, enteritis and dysentery, jaundice, chronic tracheitis, pertussis." Shanxi Chinese medicinal herbal " carries: " lower heart-fire, brings down a fever antipyretic, anti-inflammation and sterilization, antalgic and sedative.”
The present invention compared with prior art, has following beneficial effect:
Selected by Chinese medicine preparation of the present invention, medical material compatibility is suitable, meet Chinese medicine and modern medicine theory, there is effect of heat-clearing and toxic substances removing, eliminating dampness by diuresis diuresis, anti-inflammatory analgetic, supplementing QI for promoting the production of body fluid, easy to use, good absorbing effect, without bad and toxic and side effects, through clinical verification, can reconciling superficies and interior, dispel the wind bring down a fever, diuresis invigorates blood circulation, and improves body internal and external environment, thus treatment or alleviate the various symptoms of urinary tract infection, be suitable for urinary tract infection clinical treatment and nursing is applied.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The preparation method of Chinese medicine preparation of the present invention, comprises following processing step:
(1) Flos micheliae Albae, Herba Pteridis Multifidae, Semen Euryales, Herba Senecionis Kirilowi and Herba rutae are removed impurity, clean, surface uniform sprays vinegar liquid, vexed, and put interior the slow fire of pot and add and propagandize hotly to tack-free, microwave drying, is placed in mortar and grinds into powder, mistake 120 order fine powders, for subsequent use;
(2) by CUIYUNCAO, Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae), Stamen Nelumbinis, tongue spray and Herba Chelidonii decontamination, clean, microwave drying, is placed in mortar and grinds into powder, crosses 140 order fine powders, for subsequent use;
(3) Lignum et Radix Naucleae, Radix Polygoni Ciliinerve, Herba Kummerowiae Striatae, Herba Melastomatis Dodecandri and Radix Bupleuri decontamination are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, under simmer down to 60 DEG C of environment, relative density is the thick paste of 1.12 ~ 1.15, for subsequent use;
(4) Fructus Schisandrae Chinensis is cleaned, add a small amount of vinegar liquid, silently, put in pot and steam, until blackening, take out, dry, be placed in mortar and smash to pieces, get fine powder, cross 170 order fine powders, for subsequent use;
(5) fine powder obtained by above-mentioned steps (1), step (2), step (4) and the thick paste obtained by step (3) are stirred, make tablet, be the Chinese medicine preparation of described treatment urinary tract infection.
Usage and dosage: oral, every day 3 times, each 1 time of morning, noon and afternoon, each 3; Within 7 days, be 1 course for the treatment of, 1 ~ 2 course for the treatment of of the lighter, 3 ~ 4 courses for the treatment of of severe one, or follow the doctor's advice and to increase by amount.
Embodiment 2
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 3
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Embodiment 4
The raw material composition of Chinese medicine preparation effective ingredient of the present invention and weight are:
The Chinese medicine preparation preparation method processing step of the present embodiment and usage and dosage identical with embodiment 1.
Clinical data:
1, case selection:
Select my institute or outer court to make a definite diagnosis the routine clinical observation of patients of urinary tract infection 400, patient is divided into two groups at random, treatment group 200 example, 5 years old ~ 60 years old age, 49 years old mean age, the course of disease 2 months ~ 2 years, average 1 year.Matched group 200 example, 9 years old ~ 55 years old age, 45 years old mean age, the course of disease 1 month ~ 1.5 years, average 10 months.The course of disease, the degrees of symptoms of two groups of cases are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group takes Chinese medicine preparation of the present invention, oral, every day 3 times, each 1 time of morning, noon and afternoon, each 3; Within 7 days, be 1 course for the treatment of, 1 ~ 2 course for the treatment of of the lighter, 3 ~ 4 courses for the treatment of of severe one, or follow the doctor's advice and to increase by amount.
Matched group takes levofloxacin, oral, acute simplex lower urinary tract infection, a 0.1g, 2 times on the one, 5 ~ 7 days courses for the treatment of; Complexity urinary tract infection a: 0.2g, 2 times on the one, or a 0.1g, 3 times on the one, 10 ~ 14 days courses for the treatment of.
3, efficacy determination:
(1) cure: urgent micturition dysurea, dysuria, high heat such as to be felt sick at the transference cure.
(2) effective: above-mentioned symptom is alleviated to some extent, physical recovery is healthy.
(3) invalid: disease is unchanged.
4, result:
Take in the treatment group of medicine of the present invention, cure 145 examples, effective 34 examples, invalid 21 examples, cure rate 72.5%, total effective rate 89.5%.
130 examples are cured, effective 29 examples, invalid 41 examples, cure rate 65%, total effective rate 79.5% in matched group.
Above result display, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Cao, female, 6 years old, student, Luoyang, henan people.Because entering new environmental inadequacies, there is frequent micturition, urgent micturition in patient, within 1 ~ 2 hour, urinates once, and urine volume is few, and with the symptom such as inappetence, nausea and vomiting.After taking 1 course for the treatment of of Chinese medicine preparation of the present invention, the symptoms such as urgent micturition frequent micturition are obviously alleviated, after continuing to take 2 courses for the treatment of, full of vitality, and health is fully recovered.
2, what certain, man, 35 years old, peasant, people from Jiujiang.Patient's frequent micturition, urgent micturition, dysurea, bladder area is uncomfortable, and urethra has burn feeling, occurs urge incontinence time serious.Urinary tract infection is diagnosed as by my institute.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, health is rehabilitation gradually, and the symptom such as frequent micturition, dysurea is obviously alleviated, and continues to take 2 courses for the treatment of, and physical recovery is healthy.
3, Lu, female, 38 years old, workman, people from Xining, Qinghai.Patient recent right side lumbago one day, companion shiver all overs with cold, and rear appearance right side lumbago, companion shiver all overs with cold, and has urine urgency-frequency simultaneously, and the symptoms such as cloudy urine once suffered from urethritis.After taking 3 courses for the treatment of of Chinese medicine preparation of the present invention, the transference cures such as pain, health is fully recovered.
4, certain is executed, female, 41 years old, private owner, people from Lanzhou, Gansu.Patient once suffered from urinary tract infection, slight uterine erosion.Recent appearance is fat, frequent micturition hypodynia, and the soreness of waist is profound, alternate attacks of chills and fever, time have sweating, two side of body distensions, the symptoms such as corpulent tongue is large.Once took various medicine, effect is all not good.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, above symptom is clearly better, and continues to take 2 courses for the treatment of, and the state of an illness is fully recovered, and follows up a case by regular visits to and does not recur.
5, Zhang, man, 45 years old, builder, people from Xi'an, Shaanxi.There is rapid breathing in patient, the symptom of frequent micturition, frequent micturition in the recent period, took various medicine, and effect is all not good.Later stage bilateral lumbago, costovertebral angle has obvious tenderness and percussion pain, and with the symptom of fear of cold, high heat, vomiting.Urinary tract infection is diagnosed as by my institute.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, symptom obviously alleviates, and after continuing to take 3 courses for the treatment of, physical recovery is normal.
6, hole, man, 51 years old, businessman, Taiyuan, Shanxi people.Feel shiver with cold, high heat, headache, nauseating, urgent micturition, inappetence etc. during patient, check that Leukocyte Counts obviously raises through my institute, erythrocyte sedimentation rate speeds, and is diagnosed as urinary tract infection.After taking 2 courses for the treatment of of Chinese medicine preparation of the present invention, symptom obviously alleviates, and after continuing to take 2 courses for the treatment of, physical recovery is normal.

Claims (5)

1. treat a Chinese medicine preparation for urinary tract infection, it is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Flos micheliae Albae 60 ~ 90 parts of CUIYUNCAO 59 ~ 89 portions of Lignum et Radix Naucleae 57 ~ 87 portions of Herba Pteridis Multifidaes 56 ~ 86 parts
Radix Polygoni Ciliinerve 54 ~ 84 parts of Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 52 ~ 82 portions of Herba Kummerowiae Striatae 50 ~ 80 parts of Stamen Nelumbiniss 48 ~ 78 parts
Fructus Schisandrae Chinensis 46 ~ 76 portions of Semen Euryaless 45 ~ 75 parts of tongue sprays 44 ~ 74 parts of Herba Senecionis Kirilowis 43 ~ 73 parts
Herba Melastomatis Dodecandri 41 ~ 71 parts of Herba rutaes 39 ~ 69 parts of Radix Bupleuri 37 ~ 67 portions of Herba Chelidoniis 34 ~ 64 parts.
2. a kind of Chinese medicine preparation for the treatment of urinary tract infection according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Flos micheliae Albae 83 parts of CUIYUNCAO 82 portions of Lignum et Radix Naucleae 80 portions of Herba Pteridis Multifidaes 79 parts
Radix Polygoni Ciliinerve 77 parts of Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 75 portions of Herba Kummerowiae Striatae 73 parts of Stamen Nelumbiniss 71 parts
Fructus Schisandrae Chinensis 69 portions of Semen Euryaless 68 parts of tongue sprays 67 parts of Herba Senecionis Kirilowis 66 parts
Herba Melastomatis Dodecandri 64 parts of Herba rutaes 62 parts of Radix Bupleuri 60 portions of Herba Chelidoniis 57 parts.
3. a kind of Chinese medicine preparation for the treatment of urinary tract infection according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Flos micheliae Albae 76 parts of CUIYUNCAO 75 portions of Lignum et Radix Naucleae 73 portions of Herba Pteridis Multifidaes 72 parts
Radix Polygoni Ciliinerve 70 parts of Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 68 portions of Herba Kummerowiae Striatae 66 parts of Stamen Nelumbiniss 64 parts
Fructus Schisandrae Chinensis 62 portions of Semen Euryaless 61 parts of tongue sprays 60 parts of Herba Senecionis Kirilowis 59 parts
Herba Melastomatis Dodecandri 57 parts of Herba rutaes 55 parts of Radix Bupleuri 53 portions of Herba Chelidoniis 50 parts.
4. a kind of Chinese medicine preparation for the treatment of urinary tract infection according to claim 1, is characterized in that: raw material composition and the parts by weight of making described Chinese medicine preparation effective ingredient are:
Flos micheliae Albae 69 parts of CUIYUNCAO 68 portions of Lignum et Radix Naucleae 66 portions of Herba Pteridis Multifidaes 65 parts
Radix Polygoni Ciliinerve 63 parts of Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae) 61 portions of Herba Kummerowiae Striatae 59 parts of Stamen Nelumbiniss 57 parts
Fructus Schisandrae Chinensis 55 portions of Semen Euryaless 54 parts of tongue sprays 53 parts of Herba Senecionis Kirilowis 52 parts
Herba Melastomatis Dodecandri 50 parts of Herba rutaes 47 parts of Radix Bupleuri 45 portions of Herba Chelidoniis 43 parts.
5. as described in any one of Claims 1 to 4, treat a preparation method for the Chinese medicine preparation of urinary tract infection, it is characterized in that: comprise following processing step:
(1) Flos micheliae Albae, Herba Pteridis Multifidae, Semen Euryales, Herba Senecionis Kirilowi and Herba rutae are removed impurity, clean, surface uniform sprays vinegar liquid, vexed, and put interior the slow fire of pot and add and propagandize hotly to tack-free, microwave drying, is placed in mortar and grinds into powder, mistake 120 order fine powders, for subsequent use;
(2) by CUIYUNCAO, Rhizoma Nephrolepis Cordifoliae (Herba Nephrolepis Cordifoliae), Stamen Nelumbinis, tongue spray and Herba Chelidonii decontamination, clean, microwave drying, is placed in mortar and grinds into powder, crosses 140 order fine powders, for subsequent use;
(3) Lignum et Radix Naucleae, Radix Polygoni Ciliinerve, Herba Kummerowiae Striatae, Herba Melastomatis Dodecandri and Radix Bupleuri decontamination are cleaned, put into container, add the distilled water of 8 ~ 10 times amount, soak after 5 ~ 6 hours, boil 3 ~ 4 hours, extract; Again add 6 ~ 8 times amount distilled water, boil 2 ~ 3 hours, extract; Finally, add 4 ~ 6 times amount distilled water, heated and boiled 1 ~ 2 hour, extract; Merge three extracting solution, filter, obtain filtrate, under simmer down to 60 DEG C of environment, relative density is the thick paste of 1.12 ~ 1.15, for subsequent use;
(4) Fructus Schisandrae Chinensis is cleaned, add a small amount of vinegar liquid, silently, put in pot and steam, until blackening, take out, dry, be placed in mortar and smash to pieces, get fine powder, cross 170 order fine powders, for subsequent use;
(5) fine powder obtained by above-mentioned steps (1), step (2), step (4) and the thick paste obtained by step (3) are stirred, make tablet, be the Chinese medicine preparation of described treatment urinary tract infection.
CN201410719206.XA 2014-11-29 2014-11-29 Traditional Chinese medicine preparation for treating urinary tract infection and production method of traditional Chinese medicine preparation Expired - Fee Related CN104383053B (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104940563A (en) * 2015-07-15 2015-09-30 龚灿锋 Veterinary drug for treating poultry urinary system infection
CN105031177A (en) * 2015-07-09 2015-11-11 青岛华仁技术孵化器有限公司 Traditional Chinese medicine composition for treating urinary tract infection and preparation method of traditional Chinese medicine composition
CN105560745A (en) * 2016-01-04 2016-05-11 侯涛 Traditional Chinese medicine composition for treating urinary tract infection
CN106075308A (en) * 2016-07-29 2016-11-09 李华 A kind of Chinese medicine preparation for treating acute cystitis and preparation method

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1559535A (en) * 2004-03-09 2005-01-05 陈玲玲 Chinese medicine oral preparaton for treating urinary system infestation and its preparation method
CN104027617A (en) * 2014-05-15 2014-09-10 当涂县科辉商贸有限公司 Traditional Chinese medicine composition for treating urinary tract infection

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1559535A (en) * 2004-03-09 2005-01-05 陈玲玲 Chinese medicine oral preparaton for treating urinary system infestation and its preparation method
CN104027617A (en) * 2014-05-15 2014-09-10 当涂县科辉商贸有限公司 Traditional Chinese medicine composition for treating urinary tract infection

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105031177A (en) * 2015-07-09 2015-11-11 青岛华仁技术孵化器有限公司 Traditional Chinese medicine composition for treating urinary tract infection and preparation method of traditional Chinese medicine composition
CN104940563A (en) * 2015-07-15 2015-09-30 龚灿锋 Veterinary drug for treating poultry urinary system infection
CN105560745A (en) * 2016-01-04 2016-05-11 侯涛 Traditional Chinese medicine composition for treating urinary tract infection
CN106075308A (en) * 2016-07-29 2016-11-09 李华 A kind of Chinese medicine preparation for treating acute cystitis and preparation method

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