CN104382961A - Aike capsule for enhancing immunity and preparation method of Aike capsule - Google Patents
Aike capsule for enhancing immunity and preparation method of Aike capsule Download PDFInfo
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- CN104382961A CN104382961A CN201410730641.2A CN201410730641A CN104382961A CN 104382961 A CN104382961 A CN 104382961A CN 201410730641 A CN201410730641 A CN 201410730641A CN 104382961 A CN104382961 A CN 104382961A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/062—Ascomycota
- A61K36/066—Clavicipitaceae
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/074—Ganoderma
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/4841—Filling excipients; Inactive ingredients
- A61K9/4866—Organic macromolecular compounds
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Abstract
The invention discloses an Aike capsule for enhancing the immunity. The Aike capsule comprises a capsule content and a capsule shell, wherein the capsule content is prepared from the following raw and auxiliary materials in parts by weight: 90-110 parts of cordyceps militaris fruiting bodies, 45-55 parts of lucid ganoderma extractives, 45-55 parts of mushroom extractives and 50 parts of microcrystalline cellulose. A preparation method of the Aike capsule comprises the following main steps of 1, sieving; 2, mixing, 3, filling, and 4, polishing and screening. The Aike capsule for enhancing the immunity, disclosed by the invention, is prepared by taking cordyceps militaris, the lucid ganoderma extractives and the mushroom extractives as main raw materials and is reasonable and effective in compatibility, extremely-high in nutrient value and capable of enhancing the immunity of a human body and effectively relieving symptoms such as physical weakness and the like.
Description
Technical field
the present invention relates to field of health care food, particularly a kind of Ai Ke capsule increasing immunity and preparation method thereof.
Background technology
immunity is the defense mechanism of human body self, is human bioequivalence and any foreign body (virus, antibacterial etc.) eliminating external intrusion; Process is old and feeble, damage, the ability of mutant cell and virus infected cell in the own cells of dead, degeneration and identification and handling body.Immunology Today is thought, immunity is the physiological reaction of human bioequivalence and eliminating " dissident ".
" immunity " word, sees ming dynasty of china medical book " immune class side " the earliest, refers to " release epidemic disease ", namely prevent and treat the meaning of infectious disease." immunity " one word also have the ability meaning of body from viral, severe external environment, also can refer to spiritual resistance.
immunity refers to that body resists external invasion and attack, safeguards the ability of homoiostasis.Various microorganism is filled with: antibacterial, virus, mycoplasma, chlamydia, fungus etc. in air.In the hypodynamic situation of human immunity, they can become the pathogen of class as early as possible.Although human body can produce corresponding antibody to different pathogen; to resist subinfection again; but antibody has specificity and time-bounded, such as streptococcus antibody compared with protecting body again not invade by streptococcic in short-term, also can only can not resist the infection of other viruses.The people of hypoimmunity cannot resist the invasion and attack of cold virus at all, and this is only the true cause that he frequently catches a cold.
modern medicine scientific discovery, immunity is one has the factor of substantial connection with aging, and immunocyte decline is one of most important reason of aging.Some special cells of body immune system can by the antibacterial in invasion body, virus and body aging death cell, the cell suddenlyd change and cause allergic material, engulfed wholly and eliminated, thus maintain the stable of internal milieu, keep body health.But body's immunity just started at about 30 years old to subtract late, and this change quietly, slowly, constantly carries out.
the performance of hypoimmunity:
the health of hypoimmunity is easy to infected or cancer stricken; Immunity is extraordinary also can produce the immunity how insalubrious result improves child, as caused anaphylaxis, autoimmune disease etc.
a variety of causes makes immune system normally can not play protective effect, and in the case, very easily cause the infection such as antibacterial, virus, fungus, therefore hypoimmunity the most directly shows is exactly liable to illness.Because of often ill, increased the weight of the consumption of body, thus generally have a delicate constitution, the reduction of malnutrition, lethargy, fatigue and weak, appetite, the performance such as sleep disorder, sick, have an injection and take medicine the normal potluck that just gets married.At every turn sickly all to could to recover for a long time, and usually recurrent exerbation.If things go on like this can cause health and intelligent development bad, also easily bring out major disease.
underlying causes is that hypoimmunity or immunity are unsound.When immune function of human body imbalance, or when immune system is unsound, following point will recurrent exerbation: flu recurrent exerbation, tonsillitis recurrent exerbation, asthma recurrent exerbation, bronchitis recurrent exerbation, pneumonia recurrent exerbation, diarrhoea recurrent exerbation.
often feel tired, work is often felt tired spiritless, and slightly do something and just felt tired, go examination in hospital also not find what organic disease, after rest a period of time, your energy is alleviated again, and not sustainable several days, feeling of fatigue occurred again.
flu constantly, has been caught a cold into your homely food, weather has been turned cold a little, cooled off, had little time to put on more clothes you with regard to sneeze, and will experience long a period of time after flu and just can cure.
wound easily infects, and after which position of health is scratched because of carelessness, wound will be red and swollen within these few days, and even suppurate, normal person can get well soon, and therefore you will drag for a long time; Or your certain position, such as buttocks minister not only pain but also the little furuncle of itching, long again on head in a few days.
fragile the intestines and stomach, a common dish has been eaten in restaurant outside, and other people is safe and sound, and your vomiting and dirarrhea.
in the market by medicine or the health product of many enhancing immunity, but the effect of most drug is not very well, and with side effect, threatens health, therefore, market is badly in need of a kind of Ai Ke capsule increasing immunity and preparation method thereof.
Summary of the invention
the object of this invention is to provide and a kind ofly make the Ai Ke capsule and preparation method thereof having and increase immunity with Cordyceps militaris (L.) Link., Ganoderma extract, Lentinus Edodes extract for primary raw material compatibility.
object of the present invention is achieved through the following technical solutions: a kind of Ai Ke capsule increasing immunity, comprise capsule 's content and capsule shell, in capsule 's content, supplementary material by weight, Cordyceps militaris (L.) Link.sporophore 90-110 part, Ganoderma extract 45-55 part, Lentinus Edodes extract 45-55 part, microcrystalline Cellulose 50 parts.
described a kind of Ai Ke capsule increasing immunity, in capsule 's content, supplementary material is by preferred weight number, Cordyceps militaris (L.) Link.sporophore 100 parts, Ganoderma extract 50 parts, Lentinus Edodes extract 50 parts, microcrystalline Cellulose 50 parts.
described a kind of Ai Ke capsule increasing immunity, in capsule 's content, supplementary material is by preferred weight number, Cordyceps militaris (L.) Link.sporophore 90 parts, Ganoderma extract 55 parts, Lentinus Edodes extract 55 parts, microcrystalline Cellulose 50 parts.
described a kind of Ai Ke capsule increasing immunity, in capsule 's content, supplementary material is by preferred weight number, Cordyceps militaris (L.) Link.sporophore 110 parts, Ganoderma extract 45 parts, Lentinus Edodes extract 45 parts, microcrystalline Cellulose 50 parts.
described a kind of Ai Ke capsule increasing immunity, the key step of its preparation method is:
step 1. is sieved: by weight, chooses the Cordyceps militaris (L.) Link.sporophore of high-quality, Ganoderma extract, Lentinus Edodes extract, microcrystalline Cellulose, crosses 80 mesh sieves respectively, obtains each supplementary material fine powder;
step 2. mixes: by weight, and be placed in mixer by the Cordyceps militaris (L.) Link.sporophore after sieving, Ganoderma extract, Lentinus Edodes extract, microcrystalline Cellulose fine powder, mix homogeneously, obtains mixed powder;
step 3. is filled: by mixed powder filled capsules, capsule 's content 0.25g/ grain;
step 4. polishing, screening: populated capsule is carried out polishing, selects and discard defective work, obtain a kind of Ai Ke capsule increasing immunity.
cordyceps militaris (L.) Link. is also known as Cordyceps militaris (L.) Link., and wild Cordyceps militaris (L.) Link. is the one of Cordyceps, is the traditional rare Chinese medicine of China, has multiple pharmacological function.Cordyceps militaris (L.) Link. has calmness, antifatigue effect, and colleague also has antiinflammatory, improves hypoxia-bearing capability, increases immunomodulating, antitumor, the multiple medical value such as antibacterial.Wild Cordyceps militaris (L.) Link. is the one of Cordyceps, and tame Cordyceps militaris (L.) Link. and Cordyceps have similar nutritional labeling and functional component, and its food medicine is worth identical.At present, Cordyceps militaris (L.) Link. is classified as new resource food by health ministry.
ganoderma, represents luckiness, wealth and rank since ancient times, and chinese tradition medical science is considered as nourishing and fit keeping function for a long time always, consolidates the precious Chinese herbal medicine of righting.Ganoderma has become genuine food medicine dual-purpose bacterium, and Inpharm circle also pays much attention to the research and development of Ganoderma.Ganoderma has calmness, pain relieving, adjusting immunity of human body, antiinflammatory, antioxidation and anti-ageing plurality kinds of health care and the medicinal efficacy of waiting for a long time.Research shows: the chemical composition of Ganoderma mainly contains, ganoderan, triterpenoid compound, Ganoderma adenosine, trace element and organic germanium, amino acid polypeptide class, enzyme, alkaloid and small protein etc., wherein Ganoderma adenosine can improve the support capacity of blood, the heart, brain, is human immunity regulator.
lentinus Edodes is the basidiomycetes of Pleurotaceae Lentinus, and it contains multiple effective Pharmaceutical ingredients, and for thousands of years, Lentinus Edodes, already by as abundant medicinal source, treats various disease.Have the title of " delicacy from mountain " in China, it is delicious fresh and tender, containing polysaccharide, protein, aminoacid, fat, carbohydrate, vitamin and trace element etc.Recent study shows that the extract of Lentinus Edodes has the multinomial biological functions such as antiviral, antitumor and immunity moderation function.Lentinus Edodes extract is as a kind of immunomodulator, its effect is similar to host immune reinforcing agent, can maturation, the Differentiation and proliferation of immune stimulatory cell, improve host individual balance, reach and recover or improve the reactivity effect of host cell to lymphokine, stimulation and other bioactie agent.
beneficial effect of the present invention: a kind of Ai Ke capsule increasing immunity of the present invention, with Cordyceps militaris (L.) Link., Ganoderma extract, Lentinus Edodes extract for primary raw material, compatibility is rationally effective, high nutritive value, can body immunity be strengthened, effectively improve symptoms such as having a delicate constitution.
the present invention is through two groups of clinical verifications, wherein one group is that treatment group drinks the present invention, eat the present invention every day once, it within 7 days, is a course for the treatment of, another group matched group takes Yupingfeng Koufuye, every day uses once, it within 7 days, is a course for the treatment of, every group selection outpatient 110 example, wherein man 40 example, female 70 example, max age 75 years old, minimal ages 35 years old, clinical manifestation for having a delicate constitution, malnutrition, lethargy, fatigue and weak, flu are continuous, wound easily infects, the intestines and stomach is weak, table one is for taking the contrasting data after the course for the treatment of:
table 1 is taken front and back and is compared (unit: people) two groups of courses for the treatment of
there were significant differences for treatment group and matched group, thus can find out that the present invention's application clinically has significant curative effect.
Detailed description of the invention
embodiment 1
increase a Ai Ke capsule for immunity, comprise capsule 's content and capsule shell, in capsule 's content, supplementary material by weight, Cordyceps militaris (L.) Link.sporophore 90-110 part, Ganoderma extract 45-55 part, Lentinus Edodes extract 45-55 part, microcrystalline Cellulose 50 parts.
embodiment 2
increase a Ai Ke capsule for immunity, in capsule 's content, supplementary material is by preferred weight number, Cordyceps militaris (L.) Link.sporophore 100 parts, Ganoderma extract 50 parts, Lentinus Edodes extract 50 parts, microcrystalline Cellulose 50 parts.
embodiment 3
increase a Ai Ke capsule for immunity, in capsule 's content, supplementary material is by preferred weight number, Cordyceps militaris (L.) Link.sporophore 90 parts, Ganoderma extract 55 parts, Lentinus Edodes extract 55 parts, microcrystalline Cellulose 50 parts.
embodiment 4
increase a Ai Ke capsule for immunity, in capsule 's content, supplementary material is by preferred weight number, Cordyceps militaris (L.) Link.sporophore 110 parts, Ganoderma extract 45 parts, Lentinus Edodes extract 45 parts, microcrystalline Cellulose 50 parts.
embodiment 5
increase a Ai Ke capsule for immunity, the key step of its preparation method is:
step 1. is sieved: by weight, chooses the Cordyceps militaris (L.) Link.sporophore of high-quality, Ganoderma extract, Lentinus Edodes extract, microcrystalline Cellulose, crosses 80 mesh sieves respectively, obtains each supplementary material fine powder;
step 2. mixes: by weight, and be placed in mixer by the Cordyceps militaris (L.) Link.sporophore after sieving, Ganoderma extract, Lentinus Edodes extract, microcrystalline Cellulose fine powder, mix homogeneously, obtains mixed powder;
step 3. is filled: by mixed powder filled capsules, capsule 's content 0.25g/ grain;
step 4. polishing, screening: populated capsule is carried out polishing, selects and discard defective work, obtain a kind of Ai Ke capsule increasing immunity.
embodiment 6
by continuous for the capsule powders of embodiment 1 gavage mice after 30 days, the body weight of mice, internal organs/body weight ratio are had no significant effect; The paw swelling of three dosage treated animals compares with negative control group, and middle and high dosage has pole significant difference (p < 0.01, p < 0.01), positive to mouse cell immunity test result; The antibody product of three dosage treated animals compares with negative control group, and middle and high dosage group has significant difference (p < 0.01, p < 0.01), positive to mouse humoral immune result of the test; Negative to the huge function test result of biting of mouse monokaryon one; Negative to NK cells in mice activity test result.Can judge according to " health food inspection and assessment technical specification " (2003 editions), this health food Ai Ke capsule compatible combination has the function increasing immunity.
Claims (5)
1. one kind increases the Ai Ke capsule of immunity, comprise capsule 's content and capsule shell, it is characterized in that: in capsule 's content, supplementary material by weight, Cordyceps militaris (L.) Link.sporophore 90-110 part, Ganoderma extract 45-55 part, Lentinus Edodes extract 45-55 part, microcrystalline Cellulose 50 parts.
2. a kind of Ai Ke capsule increasing immunity according to claim 1, is characterized in that: in capsule 's content, supplementary material is by preferred weight number, Cordyceps militaris (L.) Link.sporophore 100 parts, Ganoderma extract 50 parts, Lentinus Edodes extract 50 parts, microcrystalline Cellulose 50 parts.
3. a kind of Ai Ke capsule increasing immunity according to claim 1, is characterized in that: in capsule 's content, supplementary material is by preferred weight number, Cordyceps militaris (L.) Link.sporophore 90 parts, Ganoderma extract 55 parts, Lentinus Edodes extract 55 parts, microcrystalline Cellulose 50 parts.
4. a kind of Ai Ke capsule increasing immunity according to claim 1, is characterized in that: in capsule 's content, supplementary material is by preferred weight number, Cordyceps militaris (L.) Link.sporophore 110 parts, Ganoderma extract 45 parts, Lentinus Edodes extract 45 parts, microcrystalline Cellulose 50 parts.
5. a kind of Ai Ke capsule increasing immunity according to claim 1-4, is characterized in that: the key step of its preparation method is:
Step 1. is sieved: by weight, chooses the Cordyceps militaris (L.) Link.sporophore of high-quality, Ganoderma extract, Lentinus Edodes extract, microcrystalline Cellulose, crosses 80 mesh sieves respectively, obtains each supplementary material fine powder;
Step 2. mixes: by weight, and be placed in mixer by the Cordyceps militaris (L.) Link.sporophore after sieving, Ganoderma extract, Lentinus Edodes extract, microcrystalline Cellulose fine powder, mix homogeneously, obtains mixed powder;
Step 3. is filled: by mixed powder filled capsules, capsule 's content 0.25g/ grain;
Step 4. polishing, screening: populated capsule is carried out polishing, selects and discard defective work, obtain a kind of Ai Ke capsule increasing immunity.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201410730641.2A CN104382961A (en) | 2014-12-05 | 2014-12-05 | Aike capsule for enhancing immunity and preparation method of Aike capsule |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201410730641.2A CN104382961A (en) | 2014-12-05 | 2014-12-05 | Aike capsule for enhancing immunity and preparation method of Aike capsule |
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| CN104382961A true CN104382961A (en) | 2015-03-04 |
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| CN201410730641.2A Pending CN104382961A (en) | 2014-12-05 | 2014-12-05 | Aike capsule for enhancing immunity and preparation method of Aike capsule |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106361781A (en) * | 2016-10-28 | 2017-02-01 | 芜湖市诺康生物科技有限公司 | Composition for enhancing immunity and preparation method of composition |
| CN107260768A (en) * | 2017-06-21 | 2017-10-20 | 云南多糖生物科技有限公司 | A kind of mushroom complex polysaccharide composition and its preparation method and application |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1101265A (en) * | 1993-10-07 | 1995-04-12 | 西北师范大学应用科技研究所 | Cordyceps and cornucervi pantotrichum extracts |
| CN102657327A (en) * | 2012-05-09 | 2012-09-12 | 韩德征 | Three-treasure shredded powder and preparation method thereof |
| KR20120114904A (en) * | 2011-04-08 | 2012-10-17 | 조선대학교산학협력단 | Preparation method of immunity-boosting kimchi |
-
2014
- 2014-12-05 CN CN201410730641.2A patent/CN104382961A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1101265A (en) * | 1993-10-07 | 1995-04-12 | 西北师范大学应用科技研究所 | Cordyceps and cornucervi pantotrichum extracts |
| KR20120114904A (en) * | 2011-04-08 | 2012-10-17 | 조선대학교산학협력단 | Preparation method of immunity-boosting kimchi |
| CN102657327A (en) * | 2012-05-09 | 2012-09-12 | 韩德征 | Three-treasure shredded powder and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 姚静等: "《药用辅料应用指南》", 31 August 2011 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106361781A (en) * | 2016-10-28 | 2017-02-01 | 芜湖市诺康生物科技有限公司 | Composition for enhancing immunity and preparation method of composition |
| CN107260768A (en) * | 2017-06-21 | 2017-10-20 | 云南多糖生物科技有限公司 | A kind of mushroom complex polysaccharide composition and its preparation method and application |
| CN107260768B (en) * | 2017-06-21 | 2018-06-22 | 云南多糖生物科技有限公司 | A kind of mushroom complex polysaccharide composition and its preparation method and application |
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Application publication date: 20150304 |