CN104381664A - Pig feed for promoting intestinal development of piglets and application of pig feed - Google Patents

Abstract

The invention discloses a pig feed for promoting intestinal development of piglets and application of the pig feed. According to the pig feed, a reasonable and scientific formula is adopted, digestive physiological characteristics and nutritional requirement of intestinal development of the piglets are considered fully, ingredients of whey powder, cane sugar, glucose, soybean oil and the like are added, the relevant property and the digestibility are improved, sufficient energy substances are provided for intestinal growth, inadequate energy supply of intestine during stress is relieved, internal cause of intestinal injury is considered, promotion of advanced intestinal maturation is considered, functional amino acids are utilized to promote intestinal growth, and proline provides a precursor of polyamine synthesis in a piglet intestine and can promote intestinal maturation to advance weaning day-old of the piglets.

Description

A kind of promote intestine of young pigs to grow pig feed and application

Technical field

The present invention relates to the application of feed addictive, be specifically related to a kind of promote intestine of young pigs to grow pig feed and application.

Background technology

Enteron aisle growth is the core of Piglet Development and the basis of growth fast.Enteron aisle is body digestion, absorbs the place of nutriment, and has important defense function.Wean a difficult problem that piglet appetite is poor, the disorders of digestion, diarrhoea, poor growth etc. are puzzlement pig industry always caused.Because the intestinal growth of piglet is not well established, early weaning very easily causes Small Intestine of Piglets Mucosa Morphology, 26S Proteasome Structure and Function changes a lot, the performance completely of Developing restraint potentiality, is the maximum technology barrier implementing early weaning.

Nutrition is the most effective means that regulation and control intestinal tract injury is repaired.Domestic and international researcher has carried out large quantifier elimination, improves intestine of young pigs environment, enhanced machine body immunity function by adding the nutrition regulation means such as enzyme preparation, acidulant, oligosaccharides and antibacterials.As passed through to add acidulant in wean daily ration, degraded stomach and intestine intestines and stomach pH value, regulates gastrointestinal bacterial flora, not only can reduce the grice diarrhoea incidence of disease, can also improve weanling pig daily gain, feed feed intake, feed conversion rate, effectively alleviate ablactation stress; Add the compositions such as Organic Selenium, vitamin E, plant extracts to be conducive to improving weanling pig immunity; Add the electrolyte balance agent such as sodium acid carbonate to be conducive to alleviating ablactation stress.

Mainly concentrate on for the regulation and control alleviating ablactation stress above and regulate gastrointestinal bacterial flora, improve body's immunity etc., but less for the consideration of the jejune alimentary canal of early-weaned piglets and intestinal tract injury internal cause.The maturity state of enteron aisle self may be the deciding factor of early weaning piglet acute stage intestinal tract injury degree.By promoting that intestine of young pigs is reached maturity in advance, it will be the nourishing regulate and control technique effectively promoting intestinal mucosa injury reparation, play growth potential.

Summary of the invention

The object of the present invention is to provide a kind of pig feed promoting intestine of young pigs to grow, this feed takes into full account the nutritional need of piglet digestive physiological characteristics and intestinal growth, add whey powder, sucrose, glucose and soybean wet goods and provide sufficient energy substance for enteron aisle grows, utilize the facilitation that functional amino grows enteron aisle simultaneously, abundant promotion enteron aisle ripen in advance, to slow down the intestinal tract injury weaning and cause, weaned piglet age in days can be advanceed to 14 ages in days.

Another object of the present invention is that a kind of pig feed promoting intestine of young pigs to grow repairs the application in intestine of young pigs preparation in preparation.

In order to achieve the above object, the present invention takes following technical measures:

Promote the pig feed that intestine of young pigs is grown, its formula is as follows:

The component of described premix is (weight portion): retinol, 0.005-0.01; Vitamine D3,0.0004-0.001; Vitamin E, 0.1-0.2; Vitamin K3,0.02-0.05; Cobastab ₁₂, 0.0001-0.0005; Riboflavin, 0.01-0.05; Nicotinic acid, 0.2-0.5; Pantothenic acid, 0.05-0.2; Choline Chloride, 4-8; Folic acid, 0.001-0.005; Vitamin B1,0.005-0.03; Vitamin B6,0.01-0.05; Biotin, 0.0005-0.002; ZnSO ₄7H ₂o, 1-4; MnSO ₄5H ₂o, 0.5-2; Iron (FeSO ₄h ₂o), 1-4; Copper CuSO ₄5H ₂o, 0.5-2; KI, 0.005-0.01; Na ₂seO ₃5H ₂o, 0.002-0.01; Carrier, 60-95.

Described acidulant and antioxidant, the acidulant for feed commercially available at present and antioxidant all can be used for the present invention.

Described carrier is the mixture of one or more in medical stone, defatted rice bran, secondary powder, powdered rice hulls, zeolite powder.

Promote the pig feed that intestine of young pigs is grown, its formula following (optimum value):

Described premix component is (weight portion): retinol, 0.0076; Vitamine D3,0.0006; Vitamin E, 0.16; Vitamin K3,0.03; Cobastab ₁₂, 0.0002; Riboflavin, 0.04; Nicotinic acid, 0.3; Pantothenic acid, 0.12; Choline Chloride, 6; Folic acid, 0.003; Vitamin B1,0.015; Vitamin B6,0.03; Biotin, 0.001; ZnSO ₄7H ₂o, 3.6; MnSO ₄5H ₂o, 0.9586; FeSO ₄h ₂o, 2.52; CuSO ₄5H ₂o, 1; KI, 0.006; Na ₂seO ₃5H ₂o, 0.008; Carrier, 85.2;

Described carrier be medical stone and defatted rice bran in mass ratio 7:3 mix.

Compared with prior art, the present invention has the following advantages:

1. the present invention fills a prescription reasonable science, take into full account the nutritional need of piglet digestive physiological characteristics and intestinal growth, add whey powder, sucrose, glucose and soybean oil and not only improve suitable moral character and digestibility, simultaneously for enteron aisle growth provides sufficient energy substance, alleviate enteron aisle stress time energy under-supply.

2. the present invention is from intestinal tract injury internal cause, considers from promotion enteron aisle ripen in advance, and utilize functional amino to promote enteron aisle growth, wherein proline provides the precursor that polyamines synthesizes in intestine of young pigs, can promote gut maturation, ahead of time weaned piglet age in days.

3. from growth performance and intestinal growth and function, the feed of feeding under this formula technique 14 days, significantly can promote 14 age in days piglet protection of intestinal mucosal barrier cells propagation, differentiation, significantly promote piglet growth, reduce diarrhoea, slow down ablactation stress damage (see Fig. 1 and Fig. 2); The feed of feeding under this formula technique 18 days, 14 ages in days wean latter 7 days intestine of young pigs structure functions are not with remarkable with age in days suckling pig difference.

Accompanying drawing explanation

Fig. 1 contrasts schematic diagram for formula and commercially available same valency groove feed for pigling described in the embodiment of the present invention 1 affect piglet growth performance.

Fig. 2 contrasts schematic diagram for formula and commercially available same valency groove feed for pigling described in the embodiment of the present invention 1 affect Small Intestine of Piglets mucosal cell proliferation.

Fig. 3 expresses to affect on Jejunum of Piglets tight junction protein for formula and commercially available same valency groove feed for pigling described in the embodiment of the present invention 1 and contrasts schematic diagram.

Fig. 4 to search for food described in the embodiment of the present invention 1 piglet of formula at the contrast schematic diagram of 14 ages in days wean latter 7 days growth performances with the not weanling pig 21 age in days growth performance of commercially available same valency creep feed of searching for food.

Detailed description of the invention

Technical scheme described in the embodiment of the present invention, if not otherwise specified, is the ordinary skill in the art, the equal available from commercial channel of described raw material.

Embodiment 1:

Promote the pig feed that intestine of young pigs is grown, its formula is as follows:

Described acidulant is the benzoic acid that in DSM, Co., Ltd produces, purity 99.5%.

Antioxidant is red No. 2, the quinoline spirit that Jiangsu Zhongdan Group Co., Ltd. produces, and Main Ingredients and Appearance is ethoxyquinoline.

The component of described premix is (by weight): retinol, 0.0076; Vitamine D3,0.0006; Vitamin E, 0.16; Vitamin K3,0.03; Cobastab ₁₂, 0.0002; Riboflavin, 0.04; Nicotinic acid, 0.3; Pantothenic acid, 0.12; Choline Chloride, 6; Folic acid, 0.003; Vitamin B1,0.015; Vitamin B6,0.03; Biotin, 0.001; ZnSO ₄7H ₂o, 3.6; MnSO ₄5H ₂o, 0.9586; FeSO ₄h ₂o, 2.52; CuSO ₄5H ₂o, 1; KI, 0.006; Na ₂seO ₃5H ₂o, 0.008; Carrier (medical stone of 70% mass ratio and the defatted rice bran of 30% mass ratio), 85.2

The preparation method of the pig feed that described promotion intestine of young pigs is grown, the steps include:

A. first popcorn and fermented bean dregs are pulverized, cross 1.0mm sieve;

B. after soybean oil fully mixes with popcorn, then mix with other raw materials, obtain powder;

C. step is gathered the powder that B obtains to granulate under 60-70 DEG C of condition, obtain particulate material;

D. step is gathered the powder that B obtains to mix in the ratio of 7 ﹕ 3 with the particulate material that the poly-C of step obtains, to obtain final product, for following examples.

Embodiment 2:

The pig feed promoting intestine of young pigs to grow repairs the application in intestine of young pigs preparation in preparation, and its application process is as follows:

Choose 16 from 4 nest piglets, be divided into 2 groups, the feed from piglet 3 age in days described in additional embodiment 1 according to the pairing of the brood principle close with body weight, control group is searched for food certain commercially available same valency groove feed for pigling, equal free choice feeding.Piglet is weaned at 14 ages in days, within the 3rd day, butchers sampling, detection experiment pig growth performance and enteron aisle structure function after wean.

Piglet growth performance is shown in Fig. 1, test group and control group birth weight are respectively 1.32 ± 0.21kg and 1.32 ± 0.24kg, and during DIFFERENT FEED to 17 of searching for food age in days, body weight is respectively 4.81kg and 5.37kg, the average last anharmonic ratio control group of test group exceeds 0.56kg, and average daily gain exceeds 0.033kg/d.

Small Intestine of Piglets fluff structures is in table 1, and Jejunum of Piglets and the ileum height of naps of the commercially available same valency groove feed for pigling of the feed ratio described in embodiment of searching for food 1 significantly improve, and the Jejunum Crypt degree of depth significantly reduces.

Jejunum of Piglets tight junction protein is expressed and is seen Fig. 3, and Jejunum of Piglets tight junction protein ZO-1, Occludin, Claudin3 and Claudin1 expression of the commercially available same valency groove feed for pigling of the feed ratio described in embodiment of searching for food 1 are significantly increased.

Visible, described in the embodiment of the present invention 1, formula significantly can promote that piglet protection of intestinal mucosal barrier cells is bred, and promotes gut maturation; Can promote that tight junction protein is expressed, and improves intestinal structure, promote intestinal tract injury reparation.

Table 1 Small Intestine of Piglets fluff structures

Embodiment 3:

The pig feed promoting intestine of young pigs to grow repairs the application in intestine of young pigs preparation in preparation, and its application process is as follows:

Choose 160 from 20 nest piglets, be divided into 2 groups according to the brood principle close with body weight pairing.

The commercially available same valency groove feed for pigling of control group piglet free choice feeding from 3 ages in days, does not wean, to 21 ages in days;

The feed of test group piglet from 3 ages in days described in additional embodiment 1, free choice feeding, until 14 age in days wean latter 7 days (21 age in days).

Detect growth performance during 21 age in days, choose 8 respectively at control group and test group and butcher sampling, detect enteron aisle structure function.

Piglet growth performance is shown in Fig. 4, the piglet 14 age in days wean of feed described in embodiment of searching for food 1, when 21 age in days, average weight is 5.87kg, daily gain is 0.270kg/d, search for food not weanling pig 21 age in days of commercially available same valency creep feed time average weight be 5.89kg, daily gain is 0.271kg/d, difference is not remarkable.Point out under guarantee piglet normal growth behavior pattern, weaned piglet age in days can be advanceed to 14 ages in days.

Claims (3)

1. promote the pig feed that intestine of young pigs is grown, its formula is as follows:

The component of described premix is, by weight: retinol, and 0.005-0.01; Vitamine D3,0.0004-0.001; Vitamin E, 0.1-0.2; Vitamin K3,0.02-0.05; Cobastab ₁₂, 0.0001-0.0005; Riboflavin, 0.01-0.05; Nicotinic acid, 0.2-0.5; Pantothenic acid, 0.05-0.2; Choline Chloride, 4-8; Folic acid, 0.001-0.005; Vitamin B1,0.005-0.03; Vitamin B6,0.01-0.05; Biotin, 0.0005-0.002; ZnSO ₄7H ₂o, 1-4; MnSO ₄5H ₂o, 0.5-2; Iron (FeSO ₄h ₂o), 1-4; Copper CuSO ₄5H ₂o, 0.5-2; KI, 0.005-0.01; Na ₂seO ₃5H ₂o, 0.002-0.01; Carrier, 60-95;

Described acidulant and antioxidant, the acidulant for feed commercially available at present and antioxidant all can use;

Described carrier is the mixture of one or more in medical stone, defatted rice bran, secondary powder, powdered rice hulls, zeolite powder.

2. pig feed according to claim 1, is characterized in that:

Described premix component is: retinol, 0.0076; Vitamine D3,0.0006; Vitamin E, 0.16; Vitamin K3,0.03; Cobastab ₁₂, 0.0002; Riboflavin, 0.04; Nicotinic acid, 0.3; Pantothenic acid, 0.12; Choline Chloride, 6; Folic acid, 0.003; Vitamin B1,0.015; Vitamin B6,0.03; Biotin, 0.001; ZnSO ₄7H ₂o, 3.6; MnSO ₄5H ₂o, 0.9586; FeSO ₄h ₂o, 2.52; CuSO ₄5H ₂o, 1; KI, 0.006; Na ₂seO ₃5H ₂o, 0.008; Carrier, 85.2;

Described carrier be medical stone and defatted rice bran in mass ratio 7:3 mix.

3. in preparation, feed according to claim 1 promotes that intestine of young pigs grows the application in feed.